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Perovskite superlattices with efficient carrier dynamics

Sheng Xu, Yusheng Lei, Yuheng Li, Chengchangfeng Lu, Qizhang Yan, Huaxin Gong, Song Zhang, Jiayun Zhou, Ruiqi Zhang, Yimu Chen, Hsinhan Tsai, Yue Gu, Hongjie Hu, Yu-Hwa Lo, Wanyi Nie, Taeyoon Lee, Jian Luo, Kesong Yang, Kyung-In Jang,

Compared with their three-dimensional counterparts, low-dimensional metal halide perovskites with periodic inorganic/organic structures have shown promising stability and hysteresis-free electrical performance, which paves the way for next-generation optoelectronic devices. However, when integrated in devices, they have relatively limited efficiencies because devices usually require carrier transport through the film thickness direction. ... Read more >>

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Dopant-Free Hole Transporting Material Based on Nonconjugated Adamantane for High-Performance Perovskite Solar Cells.

Dongyu Fan, Ren Zhang, Yuheng Li, Chengwei Shan, Wenhui Li, Yunhao Wang, Feiyang Xu, Hua Fan, Zonghao Sun, Xuehui Li, Mengshuai Zhao, Aung Ko Ko Kyaw, Gongqiang Li, Jianpu Wang, Wei Huang,

A new dopant-free hole transporting material (HTM) 4',4‴,4‴'',4‴''''-(adamantane-1,3,5,7-tetrayl)tetrakis(N,N-bis(4-methoxyphenyl)-[1,1'-biphenyl]-4-amine) (Ad-Ph-OMeTAD) (named FDY for short), which consists of a nonconjugated 3D bulky caged adamantane (Ad) as the core, triphenyl amines as side arms, and phenyl units as a linking bridge, is synthesized and applied in an inverted planar perovskite solar cell (PSC). ... Read more >>

Front Chem (Frontiers in chemistry)
[2021, 9:746365]

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Strategy of efficient estimation of soil organic content at the local scale based on the national spectral database

Hongyi Li, Yuheng Li, Meihua Yang, Songchao Chen, Shi Zhou,

The aim of this paper was to compare the prediction performance of three strategies: general global Partial least squares regression (PLSR) using CSSL with and without spiking samples, memory-based learning (MBL) using CSSL with and without spiking samples and general PLSR using only spiking samples to predict soil organic matter ... Read more >>

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3' untranslated region of Ckip-1 inhibits cardiac hypertrophy independently of its cognate protein.

Yinlong Zhao, Shukuan Ling, Jianwei Li, Guohui Zhong, Ruikai Du, Youyou Li, Yanqing Wang, Caizhi Liu, Xiaoyan Jin, Wei Liu, Tong Liu, Yuheng Li, Dingsheng Zhao, Weijia Sun, Zizhong Liu, Zifan Liu, Junjie Pan, Xinxin Yuan, Xingcheng Gao, Wenjuan Xing, Yan-Zhong Chang, Yingxian Li,

<h4>Aims</h4>3' untranslated region (3' UTR) of mRNA is more conserved than other non-coding sequences in vertebrate genomes, and its sequence space has substantially expanded during the evolution of higher organisms, which substantiates their significance in biological regulation. However, the independent role of 3' UTR in cardiovascular disease was largely unknown.<h4>Methods ... Read more >>

Eur Heart J (European heart journal)
[2021, 42(36):3786-3799]

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Targeting E3 Ubiquitin Ligase WWP1 Prevents Cardiac Hypertrophy Through Destabilizing DVL2 via Inhibition of K27-Linked Ubiquitination.

Dingsheng Zhao, Guohui Zhong, Jianwei Li, Junjie Pan, Yinlong Zhao, Hailin Song, Weijia Sun, Xiaoyan Jin, Yuheng Li, Ruikai Du, Jielin Nie, Tong Liu, Junmeng Zheng, Yixin Jia, Zifan Liu, Wei Liu, Xinxin Yuan, Zizhong Liu, Jinping Song, Guanghan Kan, Youyou Li, Caizhi Liu, Xingcheng Gao, Wenjuan Xing, Yan-Zhong Chang, Yingxian Li, Shukuan Ling,

<h4>Background</h4>Without adequate treatment, pathological cardiac hypertrophy induced by sustained pressure overload eventually leads to heart failure. WWP1 (WW domain-containing E3 ubiquitin protein ligase 1) is an important regulator of aging-related pathologies, including cancer and cardiovascular diseases. However, the role of WWP1 in pressure overload-induced cardiac remodeling and heart failure is ... Read more >>

Circulation (Circulation)
[2021, 144(9):694-711]

Cited: 2 times

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Casein Kinase-2 Interacting Protein-1 Regulates Physiological Cardiac Hypertrophy via Inhibition of Histone Deacetylase 4 Phosphorylation.

Yinlong Zhao, Shukuan Ling, Guohui Zhong, Yuheng Li, Jianwei Li, Ruikai Du, Xiaoyan Jin, Dingsheng Zhao, Zizhong Liu, Guanghan Kan, Yan-Zhong Chang, Yingxian Li,

Different kinds of mechanical stimuli acting on the heart lead to different myocardial phenotypes. Physiological stress, such as exercise, leads to adaptive cardiac hypertrophy, which is characterized by a normal cardiac structure and improved cardiac function. Pathological stress, such as sustained cardiac pressure overload, causes maladaptive cardiac remodeling and, eventually, ... Read more >>

Front Physiol (Frontiers in physiology)
[2021, 12:678863]

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Effect of electroacupuncture on postoperative cognitive dysfunction for patients undergoing total knee arthroplasty: A protocol for systematic review and meta-analysis of randomized controlled trials.

Zixuan Ye, Mingjing Ke, Tao Wang, Yingxin Guan, Liang Ou, Linbiao Zheng, Zehua Chen, Zhen Shen, Liuyi Zheng, Changfei Yuan, Wenyao Li, Jinqing Liu, Yuheng Li, Shaodan Zhang, Huai Wu, Wengang Liu, Xuemeng Xu,

<h4>Background</h4>Electroacupuncture is increasingly used in rehabilitation for postoperative cognitive dysfunction (POCD), but relevant evidence remains unclear for patients receiving total knee arthroplasty (TKA).<h4>Methods</h4>The databases research of PubMed, EMBASE, CINAHL, and China National Knowledge Infrastructure (CNKI) will be conducted from inception to December 31, 2020. The relevant randomized controlled trials (RCTs) ... Read more >>

Medicine (Baltimore) (Medicine)
[2021, 100(4):e23891]

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A selected small molecule prevents inflammatory osteolysis through restraining osteoclastogenesis by modulating PTEN activity.

Yueqi Chen, Wenhui Hu, Yiran Wang, Yuheng Li, Xiaoming Li, Haibo Li, Yong Tang, Lincheng Zhang, Yutong Dong, Xiaochao Yang, Ye Wei, Shiwu Dong,

<h4>Background</h4>Inflammatory osteolysis is a severe infectious bone disorder that occurs during orthopaedic surgery and is caused by disruptions in the dynamic balance of bone matrix homeostasis, which makes this condition a burden on surgical procedures. Developing novel therapeutic drugs about inhibiting excessive osteoclastogenesis acts as an efficient approach to preventing ... Read more >>

Clin Transl Med (Clinical and translational medicine)
[2020, 10(8):e240]

Cited: 2 times

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Global poverty dynamics and resilience building for sustainable poverty reduction

Yuheng Li, Wenhao Wu, Yongsheng Wang,

There is less than a decade left to accomplish the goal of ending global poverty by 2030. This paper investigates global poverty dynamics and finds a shift in the world’s poverty gravity center from South Asia to Africa in the period 1990–2015. Sub-Saharan Africa has become the main battlefield for ... Read more >>

(Journal of Geographical Sciences)
[2021, 31(8):1159-1170]

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The coupling of reduced type H vessels with unloading-induced bone loss and the protection role of Panax quinquefolium saponin in the male mice.

Shuai Liang, Shukuan Ling, Ruikai Du, Yuheng Li, Caizhi Liu, Junhe Shi, Jie Gao, Weijia Sun, Jianwei Li, Guohui Zhong, Zizhong Liu, Dingsheng Zhao, Huiyuan Sun, Yang Li, Xinxin Yuan, Hua Qu, Xiaoyan Jin, Dong Li, Dazhuo Shi, Yingxian Li,

Unloading-induced bone loss is a critical complication characterized by the imbalance of bone formation and resorption induced by long-term confinement in bed or spaceflight. CD31<sup>hi</sup>Emcn<sup>hi</sup> (type H) vessel is a specific subtype of capillary, which was coupled with osteogenesis. However, the change of type H vessel and its contributions to ... Read more >>

Bone (Bone)
[2021, 143:115712]

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Ginsenoside Re Treatment Attenuates Myocardial Hypoxia/Reoxygenation Injury by Inhibiting HIF-1α Ubiquitination.

Huiyuan Sun, Shukuan Ling, Dingsheng Zhao, Jianwei Li, Yang Li, Hua Qu, Ruikai Du, Ying Zhang, Feng Xu, Yuheng Li, Caizhi Liu, Guohui Zhong, Shuai Liang, Zizhong Liu, Xingcheng Gao, Xiaoyan Jin, Yingxian Li, Dazhuo Shi,

Previous studies have shown an attenuating effect of ginsenoside Re on myocardial injury induced by hypoxia/reoxygenation (H/R). However, the underlying mechanism remains unclear. This study was designed to determine the underlying mechanism by which ginsenoside Re protects from myocardial injury induced by H/R. HL-1 cells derived from AT-1 mouse atrial ... Read more >>

Front Pharmacol (Frontiers in pharmacology)
[2020, 11:532041]

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A fabrication process for flexible single-crystal perovskite devices.

Yusheng Lei, Yimu Chen, Ruiqi Zhang, Yuheng Li, Qizhang Yan, Seunghyun Lee, Yugang Yu, Hsinhan Tsai, Woojin Choi, Kaiping Wang, Yanqi Luo, Yue Gu, Xinran Zheng, Chunfeng Wang, Chonghe Wang, Hongjie Hu, Yang Li, Baiyan Qi, Muyang Lin, Zhuorui Zhang, Shadi A Dayeh, Matt Pharr, David P Fenning, Yu-Hwa Lo, Jian Luo, Kesong Yang, Jinkyoung Yoo, Wanyi Nie, Sheng Xu,

Organic-inorganic hybrid perovskites have electronic and optoelectronic properties that make them appealing in many device applications<sup>1-4</sup>. Although many approaches focus on polycrystalline materials<sup>5-7</sup>, single-crystal hybrid perovskites show improved carrier transport and enhanced stability over their polycrystalline counterparts, due to their orientation-dependent transport behaviour<sup>8-10</sup> and lower defect concentrations<sup>11,12</sup>. However, the fabrication ... Read more >>

Nature (Nature)
[2020, 583(7818):790-795]

Cited: 4 times

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miR-214 stimulated by IL-17A regulates bone loss in patients with ankylosing spondylitis.

Zizhong Liu, Feng Huang, Gui Luo, Yiwen Wang, Ruikai Du, Weijia Sun, Jianwei Li, Xinxin Yuan, Dengchao Cao, Yuheng Li, Caizhi Liu, Shuai Liang, Xiaoyan Jin, Shukuan Ling, Deqing Wang, Yingxian Li,

<h4>Objective</h4>Bone loss is common in AS, and miR-214 plays an important role in regulating bone formation. The aim of this study was to investigate the effect of miR-214, the production of which is stimulated by IL-17A, on bone loss in AS.<h4>Methods</h4>Peripheral blood was obtained from 32 patients with AS and ... Read more >>

Rheumatology (Oxford) (Rheumatology (Oxford, England))
[2020, 59(5):1159-1169]

Cited: 4 times

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Alteration of calcium signalling in cardiomyocyte induced by simulated microgravity and hypergravity.

Caizhi Liu, Guohui Zhong, Yuezhang Zhou, Yuchen Yang, Yingjun Tan, Yuheng Li, Xingcheng Gao, Weijia Sun, Jianwei Li, Xiaoyan Jin, Dengchao Cao, Xinxin Yuan, Zizhong Liu, Shuai Liang, Youyou Li, Ruikai Du, Yinlong Zhao, Jianqi Xue, Dingsheng Zhao, Jinping Song, Shukuan Ling, Yingxian Li,

<h4>Objectives</h4>Cardiac Ca<sup>2+</sup> signalling plays an essential role in regulating excitation-contraction coupling and cardiac remodelling. However, the response of cardiomyocytes to simulated microgravity and hypergravity and the effects on Ca<sup>2+</sup> signalling remain unknown. Here, we elucidate the mechanisms underlying the proliferation and remodelling of HL-1 cardiomyocytes subjected to rotation-simulated microgravity and ... Read more >>

Cell Prolif (Cell proliferation)
[2020, 53(3):e12783]

Cited: 4 times

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Stability diagrams, defect tolerance, and absorption coefficients of hybrid halide semiconductors: High-throughput first-principles characterization.

Yuheng Li, Daniel Maldonado-Lopez, Valeria Ríos Vargas, Jingning Zhang, Kesong Yang,

On the basis of the screened 29 hybrid halide compounds from our prior study [Y. Li and K. Yang, Energy Environ. Sci. 12, 2233-2243 (2019)], here, we reported a systematic computational study of the stability diagram, defect tolerance, and optical absorption coefficients for these candidate materials using high-throughput first-principles calculations. ... Read more >>

J Chem Phys (The Journal of chemical physics)
[2020, 152(8):084106]

Cited: 1 time

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Effects of spaceflight on the composition and function of the human gut microbiota.

Zizhong Liu, Gui Luo, Ruikai Du, Weijia Sun, Jianwei Li, Haiyun Lan, Pu Chen, Xinxin Yuan, Dengchao Cao, Yuheng Li, Caizhi Liu, Shuai Liang, Xiaoyan Jin, Ruifu Yang, Yujing Bi, Yanping Han, Ping Cao, Wei Zhao, Shukuan Ling, Yingxian Li,

Interaction between humans and the gut microbiota is important for human physiology. Here, the gut microbiota was analyzed via metagenomic sequencing, and the fluctuations in the gut microbiota under the conditions of spaceflight were characterized. The composition and function of the gut microbiota were substantially affected by spaceflight; however, individual ... Read more >>

Gut Microbes (Gut microbes)
[2020, 11(4):807-819]

Cited: 5 times

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Strain engineering and epitaxial stabilization of halide perovskites.

Yimu Chen, Yusheng Lei, Yuheng Li, Yugang Yu, Jinze Cai, Ming-Hui Chiu, Rahul Rao, Yue Gu, Chunfeng Wang, Woojin Choi, Hongjie Hu, Chonghe Wang, Yang Li, Jiawei Song, Jingxin Zhang, Baiyan Qi, Muyang Lin, Zhuorui Zhang, Ahmad E Islam, Benji Maruyama, Shadi Dayeh, Lain-Jong Li, Kesong Yang, Yu-Hwa Lo, Sheng Xu,

Strain engineering is a powerful tool with which to enhance semiconductor device performance<sup>1,2</sup>. Halide perovskites have shown great promise in device applications owing to their remarkable electronic and optoelectronic properties<sup>3-5</sup>. Although applying strain to halide perovskites has been frequently attempted, including using hydrostatic pressurization<sup>6-8</sup>, electrostriction<sup>9</sup>, annealing<sup>10-12</sup>, van der Waals force<sup>13</sup>, ... Read more >>

Nature (Nature)
[2020, 577(7789):209-215]

Cited: 6 times

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Dual-mode emission and transmission microscopy for virtual histochemistry using hematoxylin- and eosin-stained tissue sections.

Farzad Fereidouni, Austin Todd, Yuheng Li, Che-Wei Chang, Keith Luong, Avi Rosenberg, Yong-Jae Lee, James W Chan, Alexander Borowsky, Karen Matsukuma, Kuang-Yu Jen, Richard Levenson,

In the clinical practice of pathology, trichrome stains are commonly used to highlight collagen and to help evaluate fibrosis. Such stains do delineate collagen deposits but are not molecularly specific and can suffer from staining inconsistencies. Moreover, performing histochemical stain evaluation requires the preparation of additional sections beyond the original ... Read more >>

Biomed Opt Express (Biomedical optics express)
[2019, 10(12):6516-6530]

Cited: 5 times

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AAV-Anti-miR-214 Prevents Collapse of the Femoral Head in Osteonecrosis by Regulating Osteoblast and Osteoclast Activities.

Cheng Wang, Weijia Sun, Shukuan Ling, Yu Wang, Xin Wang, Haoye Meng, Yuheng Li, Xueling Yuan, Jianwei Li, Ruoxi Liu, Dingsheng Zhao, Qiang Lu, Aiyuan Wang, Quanyi Guo, Shibi Lu, Hua Tian, Yingxian Li, Jiang Peng,

Osteonecrosis of the femoral head, an intractable but common disease that eventually triggers collapse of the femoral head, is characterized by increased osteoclast activity and markedly decreased osteoblast activity in the necrotic region of the femoral head. MicroRNA (miRNA)-214 (miR-214) may play important roles in vertebrate skeletal development by inhibiting ... Read more >>

Mol Ther Nucleic Acids (Molecular therapy. Nucleic acids)
[2019, 18:841-850]

Cited: 5 times

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Inhibition of chemokine CX3CL1 in spinal cord mediates the electroacupuncture-induced suppression of inflammatory pain.

Yuheng Li, Zongping Fang, Nan Gu, Fuhai Bai, Yongyuan Ma, Hailong Dong, Qianzi Yang, Lize Xiong,

<h4>Purpose</h4>Chemokine CX3CL1 and its receptor CX3CR1 in the lumbar spinal cord play crucial roles in pain processing. Electroacupuncture (EA) is recognized as an alternative therapy in pain treatment due to its efficacy and safety. However, the analgesic mechanism of EA remains unclear. The aim of this study was to investigate ... Read more >>

J Pain Res (Journal of pain research)
[2019, 12:2663-2672]

Cited: 5 times

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The mechanosensitive Piezo1 channel is required for bone formation.

Weijia Sun, Shaopeng Chi, Yuheng Li, Shukuan Ling, Yingjun Tan, Youjia Xu, Fan Jiang, Jianwei Li, Caizhi Liu, Guohui Zhong, Dengchao Cao, Xiaoyan Jin, Dingsheng Zhao, Xingcheng Gao, Zizhong Liu, Bailong Xiao, Yingxian Li,

Mechanical load of the skeleton system is essential for the development, growth, and maintenance of bone. However, the molecular mechanism by which mechanical stimuli are converted into osteogenesis and bone formation remains unclear. Here we report that Piezo1, a bona fide mechanotransducer that is critical for various biological processes, plays ... Read more >>

Elife (eLife)
[2019, 8:]

Cited: 39 times

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TMCO1-mediated Ca2+ leak underlies osteoblast functions via CaMKII signaling.

Jianwei Li, Caizhi Liu, Yuheng Li, Qiaoxia Zheng, Youjia Xu, Beibei Liu, Weijia Sun, Yuan Li, Shuhui Ji, Mingwei Liu, Jing Zhang, Dingsheng Zhao, Ruikai Du, Zizhong Liu, Guohui Zhong, Cuiwei Sun, Yanqing Wang, Jinping Song, Shu Zhang, Jun Qin, Shukuan Ling, Xianhua Wang, Yingxian Li,

Transmembrane and coiled-coil domains 1 (TMCO1) is a recently identified Ca<sup>2+</sup> leak channel in the endoplasmic reticulum. TMCO1 dysfunction in humans is associated with dysmorphism, mental retardation, glaucoma and the occurrence of cancer. Here we show an essential role of TMCO1 in osteogenesis mediated by local Ca<sup>2+</sup>/CaMKII signaling in osteoblasts. ... Read more >>

Nat Commun (Nature communications)
[2019, 10(1):1589]

Cited: 10 times

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Spinal Cord Glycine Transporter 2 Mediates Bilateral ST35 Acupoints Sensitization in Rats with Knee Osteoarthritis.

Fuhai Bai, Yongyuan Ma, Haiyun Guo, Yuheng Li, Feifei Xu, Ming Zhang, Hailong Dong, Jiao Deng, Lize Xiong,

The concept of "acupoint sensitization" refers to the functional status of acupoint switches from silent to active under pathological conditions. In clinic, acupoint sensitization provides important guidance for acupoints selection in different diseases. However, the mechanism behind this phenomenon remains unclear. We generated a model of knee osteoarthritis (KOA) by ... Read more >>

Evid Based Complement Alternat Med (Evidence-based complementary and alternative medicine : eCAM)
[2019, 2019:7493286]

Cited: 4 times

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Hematopoietic stem cells and lineage cells undergo dynamic alterations under microgravity and recovery conditions.

Dengchao Cao, Jinping Song, Shukuan Ling, Shuaishuai Niu, Liang Lu, Zhengzhi Cui, Yuheng Li, Shanshan Hao, Guohui Zhong, Zhihong Qi, Weijia Sun, Xinxin Yuan, Hongxing Li, Dingsheng Zhao, Xiaoyan Jin, Caizhi Liu, Xiaorui Wu, Guanghan Kan, Hongqing Cao, Youmin Kang, Shuyang Yu, Yingxian Li,

Spaceflight leads to health risks including bone demineralization, skeletal muscle atrophy, cardiovascular dysfunction, and disorders of almost all physiologic systems. However, the impacts of microgravity on blood lineage cells and hematopoietic stem cells (HSCs) in vivo are largely unknown. In this study, we analyzed peripheral blood samples from 6 astronauts ... Read more >>

FASEB J (FASEB journal : official publication of the Federation of American Societies for Experimental Biology)
[2019, 33(6):6904-6918]

Cited: 7 times

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Sevoflurane preconditioning induces tolerance to brain ischemia partially via inhibiting thioredoxin-1 nitration.

Shiquan Wang, Yuheng Li, Jinlong Wei, Pei Li, Qianzi Yang,

<h4>Background</h4>Sevoflurane preconditioning induces brain ischemic tolerance, but the mechanism remains poorly elucidated. Nitration is an important form of post-translational modification in pathological signaling. This study was to investigate the role of thioredoxin-1 (Trx-1) nitration in neuroprotection effect induced by sevoflurane preconditioning in a transient stroke model in rats.<h4>Methods</h4>Adult male Sprague-Dawley ... Read more >>

BMC Anesthesiol (BMC anesthesiology)
[2018, 18(1):171]

Cited: 2 times

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