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Author Yueming Zhang

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Huaiqihuang (HQH) granule alleviates cyclophosphamide-induced nephrotoxicity via suppressing the MAPK/NF-κB pathway and NLRP3 inflammasome activation.

Yueming Zhang, Jian Chang, Huan Gao, Xiaoyu Qu, Jinghui Zhai, Lina Tao, Jingmeng Sun, Yanqing Song,

<h4>Context</h4>Severe nephrotoxicity greatly limits the clinical use of the common effective chemotherapeutic agent cyclophosphamide (CYP). Huaiqihuang (HQH) is a Chinese herbal complex with various pharmacological activities, widely used for treating kidney disease.<h4>Objective</h4>This study estimates the protective effect of HQH against CYP-induced nephrotoxicity in rats.<h4>Materials and methods</h4>Four groups of 10 Sprague-Dawley ... Read more >>

Pharm Biol (Pharmaceutical biology)
[2021, 59(1):1425-1431]

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High-sensitivity optical fiber hydrogen sensor based on the metal organic frameworks of UiO-66-NH2.

Hongchen Chen, Changyu Shen, Xiaoman Chen, Zhenlin Huang, Zhihao Wang, Yueming Zhang,

A hydrogen sensor with high sensitivity was demonstrated by coating the metal organic frameworks of ${\rm{UiO}}\! -\! {\rm{66 \!-\! N}}{{\rm{H}}_2}$ on an optical fiber Mach-Zehnder interferometer (MZI). The MZI was made of a fiber mismatch structure by using a core-offset fusion splicing method. The effective refractive index of the ${\rm{UiO}}\! ... Read more >>

Opt Lett (Optics letters)
[2021, 46(21):5405-5408]

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Self-Powered High-Responsivity Photodetectors Enhanced by the Pyro-Phototronic Effect Based on a BaTiO3/GaN Heterojunction.

Yueming Zhang, Jie Chen, Laipan Zhu, Zhong Lin Wang,

Perovskite and semiconductor materials are always the focus of research because of their excellent properties, including pyroelectric, photovoltaic effects, and high light absorption. On basis of this, the design of combining BaTiO<sub>3</sub> (BTO) thin films with a GaN layer to form a heterojunction structure with a pyro-phototronic effect has achieved ... Read more >>

Nano Lett (Nano letters)
[2021, 21(20):8808-8816]

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Polypharmacy and potentially inappropriate medications among elderly patients in the geriatric department at a single-center in China: A retrospective cross-sectional study.

Lina Tao, Xiaoyu Qu, Huan Gao, Jinghui Zhai, Yueming Zhang, Yanqing Song,

<h4>Abstract</h4>The aging of the population has become a worldwide concern, especially in China. Polypharmacy and potentially inappropriate medications (PIMs) are prominent issues in elderly patients. Therefore, the aim of this study was to investigate the prevalence of polypharmacy and PIMs in older inpatients and further to explore the factors associated ... Read more >>

Medicine (Baltimore) (Medicine)
[2021, 100(42):e27494]

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Characterization of the Oral and Esophageal Microbiota in Esophageal Precancerous Lesions and Squamous Cell Carcinoma.

Zhengqi Li, Lizhou Dou, Yueming Zhang, Shun He, Deli Zhao, Changqing Hao, Guohui Song, Wei Zhang, Yong Liu, Guiqi Wang,

Important evidence indicates that the microbiota plays a key role in esophageal squamous cell carcinoma (ESCC). Here, paired saliva and brush specimens were obtained from 276 participants undergoing upper gastrointestinal endoscopic examination before or during screening for upper gastrointestinal (UGI) cancer. The esophageal microbiota was investigated by 16S rRNA gene ... Read more >>

Front Cell Infect Microbiol (Frontiers in cellular and infection microbiology)
[2021, 11:714162]

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Endoscopic submucosal dissection of a neoplastic lesion in the epiglottis.

Zhengqi Li, Yong Liu, Lizhou Dou, Yueming Zhang, Guiqi Wang,

Endoscopy (Endoscopy)
[2021, :]

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Glycogen Metabolism Predicts the Efficacy of Immunotherapy for Urothelial Carcinoma.

Yueming Zhang, Xuechun Li, Rui Zhou, Anqi Lin, Manming Cao, Qingwen Lyu, Peng Luo, Jian Zhang,

Urothelial cancer (UC) is one of the common refractory tumors and chemotherapy is the primary treatment for it. The advent of immune checkpoint inhibitors (ICI) has facilitated the development of treatment strategies for UC patients. To screen out UC patients sensitive to ICI, researchers have proposed that PD-L1, tumor mutation ... Read more >>

Front Pharmacol (Frontiers in pharmacology)
[2021, 12:723066]

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The value of endoscopic resection for non-ampullary duodenal lesions: A single-center experience.

Zhengqi Li, Lizhou Dou, Yong Liu, Yueming Zhang, Shun He, Jiqing Zhu, Yan Ke, Xudong Liu, Yumeng Liu, Hoiloi Ng, Guiqi Wang,

<h4>Background</h4>To observe and preliminarily evaluate the efficacy and safety of endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) in the treatment of non-ampullary duodenal lesions (NADLs).<h4>Methods</h4>This retrospective observational study included 84 patients who underwent endoscopic resection (ER) with non-ampullary duodenal lesions, between March 2010 and November 2020, at the ... Read more >>

Saudi J Gastroenterol (Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association)
[2021, 27(5):302-308]

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The effects of smoking and drinking on the oral and esophageal microbiota of healthy people.

Zhengqi Li, Yong Liu, Lizhou Dou, Yueming Zhang, Shun He, Deli Zhao, Wei Zhang, Guiqi Wang,

<h4>Background</h4>To explore the effects of smoking and drinking on the microbiota in the saliva and three segments of the esophagus (upper, middle, and lower) in healthy individuals.<h4>Methods</h4>Paired saliva and brush specimens were obtained from 76 participants who underwent upper gastrointestinal (UGI) endoscopic examination for UGI cancer screening. The esophageal microbiota ... Read more >>

Ann Transl Med (Annals of translational medicine)
[2021, 9(15):1244]

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Ginsenoside Rg3 attenuates cisplatin-induced kidney injury through inhibition of apoptosis and autophagy-inhibited NLRP3.

Jinghui Zhai, Huan Gao, Shuo Wang, Sixi Zhang, Xiaoyu Qu, Yueming Zhang, Lina Tao, Jingmeng Sun, Yanqing Song, Li Fu,

The NOD-like receptor family pyrin domain-containing (NLRP3) inflammasomes is centrally implicated in cisplatin (CP)-induced kidney injury. Autophagy is critical for inhibiting production of NLRP3 protein that effectively reduces the inflammatory response. Ginsenoside Rg3 (SY), an active component extracted from ginseng, is reported to protect against CP-induced nephrotoxicity. However, the mechanisms ... Read more >>

J Biochem Mol Toxicol (Journal of biochemical and molecular toxicology)
[2021, 35(11):e22896]

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D-dimer: The Risk Factor and Predictive Indicator of Necrotizing Pneumonia in Children.

Yueming Zhang, Lihong Xin, Zhen Wang, Wen Zhang, Dong Wang,

<h4>Background</h4>Necrotizing pneumonia (NP) is a severe complication of community-acquired pneumonia in children. This article assesses the risk factors and the diagnostic value of D-dimer for NP in children.<h4>Methods</h4>The selected patients with lobar pneumonia were divided into two groups, namely: the NP group and the pneumonia only group. This article conducted ... Read more >>

Clin Lab (Clinical laboratory)
[2021, 67(7):]

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Mid-Infrared Luminescence of the High Stability Perovskite CsPb1-xErxBr3-ZrF4-BaF2-LaF3-AlF3-NaF Fluoride Glass.

Hao Yin, Xiaosong Zhang, Lan Li, Zhaowei Zhang, Xiaokai Gong, Rukun Ding, Chao Li, Yueming Zhang,

Perovskites have been studied because of their adjustable wavelength range, high color purity, and wide color gamut. However, they still face some problems such as poor stability and insufficient infrared luminescence. The perovskite glass can improve the stability and luminescence properties of the perovskite. In this paper, a highly stable ... Read more >>

ACS Appl Mater Interfaces (ACS applied materials & interfaces)
[2021, 13(25):30008-30019]

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Positive Impact of Intraoperative Epidural Ropivacaine Infusion on Oncologic Outcomes in Pancreatic Cancer Patients Undergoing Pancreatectomy: A Retrospective Cohort Study.

Wannan Chen, Yaolin Xu, Yueming Zhang, Wenhui Lou, Xiaodan Han,

<b>Background:</b> Previous literatures have demonstrated that regional anesthesia such as epidural anesthesia may affect long-term survival of cancer patients. In the present study, we conducted a retrospective cohort study to investigate the survival impact of intraoperatively epidural ropivacaine infusion on pancreatic ductal adenocarcinoma (PDAC) patients. <b>Methods:</b> PDAC patients who underwent ... Read more >>

J Cancer (Journal of Cancer)
[2021, 12(15):4513-4521]

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The efficacy of the application of the curative criteria of the 5rd edition Japanese gastric cancer treatment guidelines for early adenocarcinoma of the esophagogastric junction treated by endoscopic submucosal dissection.

Zhihao Chen, Yong Liu, Lizhou Dou, Yueming Zhang, Shun He, Guiqi Wang,

<h4>Background</h4>The curative criteria after endoscopic submucosal dissection for early gastric carcinoma were updated by the Japanese Gastric Cancer Association. No study has shown promising results with endoscopic submucosal dissection for early adenocarcinoma of esophagogastric junction based on the new curative criteria. The purpose of this study was to validate clinical ... Read more >>

Saudi J Gastroenterol (Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association)
[2021, 27(2):97-104]

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Autologous esophageal mucosa with polyglycolic acid transplantation and temporary stent implantation can prevent stenosis after circumferential endoscopic submucosal dissection.

Yong Liu, Zhengqi Li, Lizhou Dou, Yueming Zhang, Shun He, Jiqing Zhu, Yan Ke, Xudong Liu, Yumeng Liu, Hoiloi Ng, Guiqi Wang,

<h4>Background</h4>This research aimed at investigating the safety and efficacy of autologous esophageal mucosa (AEM) with polyglycolic acid (PGA) transplantation and temporary stent implantation (TSI) in preventing esophageal stenosis (ES) after early esophageal cancer (EC) surgery.<h4>Methods</h4>Between April 2019 and October 2020, patients scheduled for circumferential endoscopic submucosal dissection (ESD) were prospectively ... Read more >>

Ann Transl Med (Annals of translational medicine)
[2021, 9(7):546]

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Submucosal tunneling endoscopic resection of an exogenic esophageal mass in the mediastinum (with video).

Zhengqi Li, Yong Liu, Lizhou Dou, Yueming Zhang, Guiqi Wang,

Gastroenterol Rep (Oxf) (Gastroenterology report)
[2021, 9(3):272-273]

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Comparing long-term outcomes between endoscopic submucosal dissection (ESD) and endoscopic mucosal resection (EMR) for type II esophagogastric junction neoplasm.

Yong Liu, Shun He, Yueming Zhang, Lizhou Dou, Xiao Liu, Xinying Yu, Ning Lu, Liyan Xue, Guiqi Wang,

<h4>Background</h4>Endoscopic submucosal dissection (ESD) and endoscopic mucosal resection (EMR) are used to remove esophagogastric junction (EGJ) neoplasm. This study aimed to compare feasibility, safety, and effectiveness between ESD and EMR to help endoscopists choose treatment methods.<h4>Methods</h4>A total of 130 patients with EGJ neoplasm underwent endoscopic resection, including 52 patients with ... Read more >>

Ann Transl Med (Annals of translational medicine)
[2021, 9(4):322]

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Age and Mutations as Predictors of the Response to Immunotherapy in Head and Neck Squamous Cell Cancer.

Yueming Zhang, Anqi Lin, Yonghe Li, Weimin Ding, Hui Meng, Peng Luo, Jian Zhang,

The immunosuppressive tumor microenvironment plays an essential role in the treatment of head and neck squamous cell carcinoma (HNSC). Compared to traditional chemoradiotherapy, immune checkpoint inhibitors (ICIs) have become increasingly important in HNSC therapy. Prior studies linked the efficacy of ICIs to PD-L1, microsatellite instability (MSI), HPV infection, tumor mutation ... Read more >>

Front Cell Dev Biol (Frontiers in cell and developmental biology)
[2020, 8:608969]

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Altered metabolic profiles and biomarkers associated with astragaloside IV-mediated protection against cisplatin-induced acute kidney injury in rats: An HPLC-TOF/MS-based untargeted metabolomics study.

Yanqing Song, Tingting Hu, Huan Gao, Jinghui Zhai, Jiawei Gong, Yueming Zhang, Lina Tao, Jingmeng Sun, Zhiyuan Li, Xiaoyu Qu,

Cisplatin (CDDP)-induced acute kidney injury (AKI) limits the therapeutic use of CDDP, which urgently needs to be addressed. Our previous study demonstrated that astragaloside IV (AS IV), an active compound of the traditional Chinese herb Astragalus membranaceus, alleviated CDDP-induced AKI. To explore the mechanism, we performed a metabolomics study to ... Read more >>

Biochem Pharmacol (Biochemical pharmacology)
[2021, 183:114299]

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miRNA-486-5p Promotes COPD Progression by Targeting HAT1 to Regulate the TLR4-Triggered Inflammatory Response of Alveolar Macrophages.

Jie Zhang, Zhongneng Xu, Lianhua Kong, Hong Gao, Yueming Zhang, Yulong Zheng, Yufeng Wan,

<h4>Purpose</h4>The aim of this study was to investigate the role of <i>miRNA-486-5p</i> in chronic obstructive pulmonary disease (COPD) progression and the underlying molecular mechanisms.<h4>Materials and methods</h4>Aberrant miRNA expression profiles between smokers and nonsmokers, and those between COPD patients and normal subjects were analyzed using microarray datasets and reverse-transcriptase quantitative polymerase ... Read more >>

Int J Chron Obstruct Pulmon Dis (International journal of chronic obstructive pulmonary disease)
[2020, 15:2991-3001]

Cited: 1 time

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Prognostic value of preoperative glucose to lymphocyte ratio in patients with resected pancreatic cancer.

Yueming Zhang, Yaolin Xu, Dansong Wang, Tiantao Kuang, Wenchuan Wu, Xuefeng Xu, Dayong Jin, Wenhui Lou,

<h4>Background</h4>Inflammatory factors and fasting blood glucose were verified to be associated with the prognosis of pancreatic ductal adenocarcinoma. The goal of this study is to confirm the prognostic role of preoperative blood glucose to lymphocyte ratio for patients with resected pancreatic ductal adenocarcinoma.<h4>Methods</h4>A total of 259 pancreatic ductal adenocarcinoma patients ... Read more >>

Int J Clin Oncol (International journal of clinical oncology)
[2021, 26(1):135-144]

Cited: 3 times

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Minimally invasive photothermal ablation assisted by laparoscopy as an effective preoperative neoadjuvant treatment for orthotopic hepatocellular carcinoma.

Qiaolin Li, Kang Chen, Wenchao Huang, Haosong Ma, Xingyang Zhao, Jinde Zhang, Yueming Zhang, Chihua Fang, Liming Nie,

Nanoparticle-based photothermal ablation (PTA) has been intensively investigated recently. However, the poor biocompatibility of most PTA agents and potential long-term toxicity obstruct their clinical translation. Meanwhile, previous PTA studies are limited to surface tumors because of insufficient light penetration depth of near-infrared (NIR) light for deep abdominal tumors. Therefore, minimally ... Read more >>

Cancer Lett (Cancer letters)
[2021, 496:169-178]

Cited: 3 times

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Safety and efficacy of endoscopic submucosal dissection for metachronous early cancer or precancerous lesions emerging at the anastomotic site after curative surgical resection of colorectal cancer.

Zhihao Chen, Lizhou Dou, Yueming Zhang, Shun He, Yong Liu, Huizi Lei, Guiqi Wang,

<h4>Background</h4>The incidence of metachronous early cancer or precancerous lesions (MECPL) emerging at the anastomotic site (AS) after curative surgical resection of colorectal cancer (CRC) is so low that few study have been conducted to explore the clinical characteristics, diagnosis and treatment of these lesions. Endoscopic submucosal dissection (ESD) is technically ... Read more >>

Ann Transl Med (Annals of translational medicine)
[2020, 8(21):1411]

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Investigation of a simple coded-aperture based multi-narrow beam x-ray luminescence computed tomography system.

Yueming Zhang, Qingwei Guo, Limin Zhang, Jiao Li, Feng Gao, Jingying Jiang, Zhongxing Zhou,

The purpose of this paper is to introduce and study a multi-narrow beam X-ray Luminescence Computed Tomography (XLCT) system based on a simple coded aperture. The proposed XLCT system is studied through simulations of x rays and diffuse light propagation and the implementation of the multi-narrow beam XLCT reconstruction algorithm. ... Read more >>

Rev Sci Instrum (The Review of scientific instruments)
[2020, 91(9):093101]

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miRNA-486-5p Promotes COPD Progression by Targeting HAT1 to Regulate the TLR4-Triggered Inflammatory Response of Alveolar Macrophages

Jie Zhang, Zhongneng Xu, Lianhua Kong, Hong Gao, Yueming Zhang, Yulong Zheng, Yufeng Wan,

<h4>Background: </h4> The aim of this study is to investigate the key regulatory miRNA-486-5p and underlying molecular mechanisms in chronic obstructive pulmonary disease (COPD) progression. <h4>Methods: </h4>: Aberrant miRNA expression in smokers compared to non-smokers and COPD compared to normal was analyzed using microarray datasets and reverse-transcriptase quantitative polymerase chain ... Read more >>

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