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Author Yuanchao Li

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The value of lymphocyte count in determining the severity of COVID-19 and estimating the time for nucleic acid test results to turn negative.

Yuanchao Li, Tuoyun Yang, Sicong Wang, Junbo Zheng, Jing Zhou, Min Jiang, Tong Zhou, Yang Cao, Hongliang Wang,

Peripheral blood lymphocyte count is shown to be decreased in patients with COVID-19 in the early stage of the disease. The degree of lymphocyte count reduction is related to COVID-19 severity and could be used as an indicator to reflect the disease severity. Our aim was to investigate the value ... Read more >>

Bosn J Basic Med Sci (Bosnian journal of basic medical sciences)
[2020, :]

Cited: 0 times

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An in situ chemically and physically confined sulfur-polymer composite for lithium-sulfur batteries with carbonate-based electrolytes.

Jingjing Ma, Guangri Xu, Yuanchao Li, Chuangye Ge, Xiaobo Li,

An in situ chemically and physically confined sulfur-polymer composite (denoted as SPANI) is synthesized by sulfurizing PANI through a one-step thermal treatment. The SPANI cathode exhibits excellent cycling stability in commercial carbonate-based electrolytes. It offers a new insight into sulfur cathode design for high performance Li-S batteries. ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2018, 54(100):14093-14096]

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A retrospective study on comparing the surgery and microneedles radiofrequency and microwaves treatment in axillary osmidrosis.

Yuanchao Li, Zhenggen Huang, Lei Ran, Wei Wang, Xiaoqin Yu, Rupeng Wang,

Objective: To compare the traditional treatment of minimally invasion surgery with the evolving treatments of microneedles radiofrequency and microwaves, this study mainly focused on the clinical efficacy and the incidence rate (IR) of complications among three treatments.Methods: From August 2017 to August 2018, a total of 76 patients with bilateral ... Read more >>

J Dermatolog Treat (The Journal of dermatological treatment)
[2020, :1-7]

Cited: 0 times

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The application of strong matrix management and PDCA cycle in the management of severe COVID-19 patients.

Yuanchao Li, Hongliang Wang, Jundong Jiao,

Crit Care (Critical care (London, England))
[2020, 24(1):157]

Cited: 1 time

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A rational design of excellent light-absorbing dyes with different N-substituents at the phenothiazine for high efficiency solar cells.

Yuanchao Li, Xin Li, Yanling Xu,

Dye-sensitized solar cells (DSSCs) have attracted great interest due to their simple fabrication process and low cost. However, most organic dyes with D-π-A configuration usually exhibit narrow absorption band, leading to poor light harvesting ability and great loss on photon conversion efficiency. In this research, a series of excellent light-absorbing ... Read more >>

Spectrochim Acta A Mol Biomol Spectrosc (Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy)
[2020, 234:118241]

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Inhibitory Effect of Curcumin on Artery Restenosis Following Carotid Endarterectomy and Its Associated Mechanism in vitro and in vivo.

Dapeng Zhang, Yanhui Yang, Yuanchao Li, Guodong Zhang, Zhenguo Cheng,

Objective:The present study aimed to assess the effect of curcumin (Cur) on carotid artery restenosis following carotid endarterectomy (CEA) and its associated mechanism in vivo and in vitro. Methods:Ang II was used to induce excessive proliferation of rabbit aortic smooth muscle cells (CCC-SMC-1) in order to establish a hemadostenosis cell ... Read more >>

Drug Des Devel Ther (Drug design, development and therapy)
[2020, 14:855-866]

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Carbon nanotube hollow polyhedrons derived from [email protected] coupled to electro-deposited gold nanoparticles for voltammetric determination of acetaminophen.

Yafeng Jin, Xiaobo Li, Chuangye Ge, Jingjing Ma, Yuanchao Li, Erqing Zhao, Shuwen Yao, Guangri Xu, Donghao Li,

A comparative study was carried out on the electrochemical behavior of three carbonized zeolitic imidazolate frameworks (ZIFs) synthesized through solvothermal pyrolysis. An electrochemical sensor for acetaminophen (ACT) was subsequently developed. The sensor was made by coating the glassy carbon electrode (GCE) with cobalt-nitrogen co-doped carbon nanotube hollow polyhedron (Co-NCNHP), which ... Read more >>

Mikrochim Acta (Mikrochimica acta)
[2019, 187(1):6]

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Mechanochemical Degrafting of a Surface-Tethered Poly(acrylic acid) Brush Promoted Etching of Its Underlying Silicon Substrate.

Yuanchao Li, Yiliang Lin, Yunkai Dai, Yeongun Ko, Jan Genzer,

The stability of surface-tethered polyelectrolyte brushes has been investigated during the past few years. We have previously reported on the degrafting of poly(acrylic acid) (PAA) polymer brushes from flat silicon substrates. Here, we present a detailed study on the effects of NaCl concentration and the grafting density and molecular weight ... Read more >>

Langmuir (Langmuir : the ACS journal of surfaces and colloids)
[2019, 35(42):13693-13699]

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Separation and recovery of carbon powder in anodes from spent lithium-ion batteries to synthesize graphene.

Li Yang, Liu Yang, Guangri Xu, Qigao Feng, Yuanchao Li, Erqing Zhao, Jingjing Ma, Shumin Fan, Xiaobo Li,

Based on the structural characteristics of the anodes of lithium-ion batteries, an improved Hummers' method is proposed to recycle the anode materials of spent lithium-ion batteries into graphene. In order to effectively separate the active material from the copper foil, water was selected as an ultrasonic solvent in this experiment. ... Read more >>

Sci Rep (Scientific reports)
[2019, 9(1):9823]

Cited: 1 time

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(5R)-5-hydroxytriptolide ameliorates liver lipid accumulation by suppressing lipid synthesis and promoting lipid oxidation in mice.

Yunxia Dong, Henglei Lu, Qiang Li, Xinming Qi, Yuanchao Li, Zean Zhang, Jing Chen, Jin Ren,

AIMS:(5R)-5-hydroxytriptolide (LLDT-8) is a triptolide analog with excellent capability against cancers, cerebral ischemic injury and rheumatoid arthritis. Here, we discovered its hepatoprotective effects in a mouse model of non-alcoholic fatty liver disease (NAFLD) by ameliorating liver lipid accumulation. MAIN METHODS:Male C57BL/6J mice were fed with a high-fat/high-fructose (HFHFr) diet for ... Read more >>

Life Sci. (Life sciences)
[2019, 232:116644]

Cited: 2 times

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Design, Electron Transfer Process, and Opto-Electronic Property of Solar Cell Using Triphenylamine-Based D-π-A Architectures.

Yuanchao Li, Lu Mi, Haibin Wang, Yuanzuo Li, Jianping Liang,

A series of D-π-A type dyes were designed based on the experimentally synthesized A1 by introducing different functional groups on the donor and π-spacer, and the optical and electrical properties were calculated by using density functional theory (DFT) and time-dependent DFT (TD-DFT). P1⁻P6 present highest light harvesting efficiency (LHE), driving ... Read more >>

(Materials (Basel, Switzerland))
[2019, 12(1):]

Cited: 1 time

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Glucocorticoid insensitivity by staphylococcal enterotoxin B in keratinocytes of allergic dermatitis is associated with impaired nuclear translocation of the Glucocorticoid Receptor α.

Ke Huang, Lei Ran, Wei Wang, Rong Zhou, Xiaowei Cai, Ran Li, Yuanchao Li, Chunli Zhou, Wei He, Rupeng Wang,

BACKGROUND:staphylococcal enterotoxin plays an important role in patients with glucocorticoid (GC)-resistant atopic dermatitis (AD), but the exact mechanism is not fully understood. OBJECTIVE:The aim of this study was to investigate the mechanisms underlying the ability of staphylococcal enterotoxin B (SEB) to induce steroid insensitivity through impaired nuclear translocation of GRα ... Read more >>

J. Dermatol. Sci. (Journal of dermatological science)
[2018, 92(3):272-280]

Cited: 1 time

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Biomechanical evaluation of cervical disc replacement with a novel prosthesis based on the physiological curvature of endplate.

Jigang Lou, Yuanchao Li, Beiyu Wang, Yang Meng, Quan Gong, Hao Liu,

Most of the current available cervical disc prostheses present a flat surface instead of an arcuate surface which is most similar to the morphology of cervical endplate. Therefore, we designed a novel prosthesis (Pretic-I, Trauson) based on the physiological curvature of the cervical endplate. Biomechanical evaluation of cervical disc replacement ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2018, 13(1):41]

Cited: 1 time

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Temperature-Driven Local Acclimatization of Symbiodnium Hosted by the Coral Galaxea fascicularis at Hainan Island, China.

Guowei Zhou, Lin Cai, Yuanchao Li, Haoya Tong, Lei Jiang, Yuyang Zhang, Xinming Lei, Minglan Guo, Sheng Liu, Pei-Yuan Qian, Hui Huang,

The success of coral reef ecosystems largely depends on mutualistic symbiosis between scleractinian corals and the dinoflagellate photosymbiont Symbiodinium spp. However, further investigation is needed to elucidate the flexibility of coral-algae associations in response to environmental changes. In this study, we applied a molecular method (high-throughput internal transcribed spacer 2 ... Read more >>

(Frontiers in microbiology)
[2017, 8:2487]

Cited: 3 times

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In vitro biomechanical comparison after fixed- and mobile-core artificial cervical disc replacement versus fusion.

Jigang Lou, Yuanchao Li, Beiyu Wang, Yang Meng, Tingkui Wu, Hao Liu,

In vitro biomechanical analysis after cervical disc replacement (CDR) with a novel artificial disc prosthesis (mobile core) was conducted and compared with the intact model, simulated fusion, and CDR with a fixed-core prosthesis. The purpose of this experimental study was to analyze the biomechanical changes after CDR with a novel ... Read more >>

(Medicine)
[2017, 96(41):e8291]

Cited: 2 times

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LLDT-288, a novel triptolide analogue exhibits potent antitumor activity in vitro and in vivo.

Hongtao Xu, Xiaoting Fan, Guanjun Zhang, Xiaoyu Liu, Zhihong Li, Yuanchao Li, Biao Jiang,

(14S)-14β-(1-(2-morpholinoethyl)-1H-indazol-5-ylamino)mthylepitriptolide (LLDT-288) was a novel C14β-heterocycle aminomethyl substituent triptolide analogue, which showed comparable cytotoxicity to triptolide. Here we demonstrated that LLDT-288 displayed broad-spectrum, potent antitumor activity, effectively against drug-resistance cancer cells, and induced apoptosis in vitro, but exerted low toxicity. Moreover, it exhibited a remarkable microsomal stability, and showed no ... Read more >>

Biomed. Pharmacother. (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie)
[2017, 93:1004-1009]

Cited: 4 times

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Identification of a diverse synthetic abietane diterpenoid library for anticancer activity.

Hongtao Xu, Lili Liu, Xiaoting Fan, Guanjun Zhang, Yuanchao Li, Biao Jiang,

A diverse natural-product-like synthetic abietane diterpenoid library contains about 56 compounds were obtained, and evaluated for their potential in vitro cytotoxic or antitumor activity against A549, PC-3 and SKOV-3 tumor cell lines by SRB assay. Treatment of A549 cells with the most potent compound ketone 19 showed induction of apoptosis, ... Read more >>

Bioorg. Med. Chem. Lett. (Bioorganic & medicinal chemistry letters)
[2017, 27(3):505-510]

Cited: 6 times

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The 2nd International Conference on Water Resource and Environment (WRE 2016).

Zhouli Liu, Wei Chen, Xingyuan He, Shuai Yu, Weihang Ding, Jianjun Liu, Yuliang Wu, Kaixiang Fan, Yuanchao Li, Xinqing Zheng, Shiquan Chen, Haiqun Xie, Jie Li, Zhuomin Wang, Li Xue, Zhiyang Lie, Weilong Huang, Tongtong Zhou, Kai Gao, Tiexia Zhu, Weiteng Mao, Pei Yu, Xinfang Lv, Yunchun Li, Peixi Su, Rui Shi, Yong Jiang, Xingbin Chen, Shichu liang, Junfeng Xu, Jiwei Zhu, Zhao Zhai, Linan Zhou, Yun Le, Li Cao, Ping Lu, Zhiqian Huang, Bei Zhou, Zhirong Zheng, Shihai Lv, Chaoyang Feng, Nan Song, Yan Liu, Xinxin Lu, Yawen Fan, Jianfei Guan, Jihua Wang, Xueping Zhang,

Table of contents01 The eco-toxicological effects of cadmium stress on five ornamental plantsZhouli Liu, Wei Chen, Xingyuan He, Shuai Yu, Weihang Ding02 Study on the formation and release mechanisms of hydrogen sulfide in Longtan coal mineJianjun Liu, Yuliang Wu, Kaixiang Fan03 Coral bleaching in the North Reef of China’s Xisha ... Read more >>

BMC Ecol. (BMC ecology)
[2016, 16(Suppl 2):71-74]

Cited: 0 times

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Identification of novel small-molecule inhibitors targeting menin-MLL interaction, repurposing the antidiarrheal loperamide.

Liyan Yue, Juanjuan Du, Fei Ye, Zhifeng Chen, Lianchun Li, Fulin Lian, Bidong Zhang, Yuanyuan Zhang, Hualiang Jiang, Kaixian Chen, Yuanchao Li, Bing Zhou, Naixia Zhang, Yaxi Yang, Cheng Luo,

Leukemia with a mixed lineage leukemia (MLL) rearrangement, which harbors a variety of MLL fusion proteins, has a poor prognosis despite the latest improved treatment options. Menin has been reported to be a required cofactor for the leukemogenic activity of MLL fusion proteins. Thus, the disruption of the protein-protein interactions ... Read more >>

Org Biomol Chem (Organic & biomolecular chemistry)
[2016, 14(36):8503-8519]

Cited: 3 times

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Rhodium(iii)-catalyzed alkylation of primary C(sp(3))-H bonds with α-diazocarbonyl compounds.

Wei Hou, Yaxi Yang, Yunxiang Wu, Huijin Feng, Yuanchao Li, Bing Zhou,

Rh(iii)-catalyzed intermolecular chelation-assisted insertion of carbenes derived from α-diazocarbonyl compounds into non-acidic primary sp(3) C-H bonds, for the first time, is reported under mild reaction conditions, thus affording a good complement to previous metal-carbenoid-induced primary C(sp(3))-H insertion reactions. We believe that this method will open up a new avenue for ... Read more >>

Chem. Commun. (Camb.) (Chemical communications (Cambridge, England))
[2016, 52(62):9672-9675]

Cited: 9 times

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LLDT-8 protects against cerebral ischemia/reperfusion injury by suppressing post-stroke inflammation.

Yanke Chen, Li Zhang, Jingshu Ni, Xiaoyu Wang, Jian Cheng, Yuanchao Li, Xuechu Zhen, Ting Cao, Jia Jia,

(5R)-5-Hydroxytriptolide (LLDT-8), an analogue of triptolide, displays lower toxicity compared to triptolide and has comparable immunosuppressive effects. We investigated the anti-inflammatory and neuroprotective effects of LLDT-8 on cerebral ischemia/reperfusion injury.Nitric oxide production from microglia was assessed by measuring the nitrite concentration in the culture medium with Griess reagent. Microglial cells ... Read more >>

J. Pharmacol. Sci. (Journal of pharmacological sciences)
[2016, 131(2):131-137]

Cited: 10 times

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Valproate ameliorates nitroglycerin-induced migraine in trigeminal nucleus caudalis in rats through inhibition of NF-кB.

Yuanchao Li, Qin Zhang, Dandan Qi, Li Zhang, Lian Yi, Qianqian Li, Zhongling Zhang,

As a complex nervous system disease, migraine causes severe healthy and social issues worldwide. Valproate (VPA) is a widely used treatment agent against seizures and bipolar disorder, and its function to alleviate damage due to migraine has also been verified in clinical investigations. However, the mechanism underlying the protective effect ... Read more >>

J Headache Pain (The journal of headache and pain)
[2016, 17:49]

Cited: 10 times

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A biomechanical comparison of 3 different posterior fixation techniques for 2-level lumbar spinal disorders.

Fubing Liu, Zhenzhou Feng, Tianze Liu, Qinming Fei, Chun Jiang, Yuanchao Li, Xiaoxing Jiang, Jian Dong,

This study sought to make a biomechanical comparison of 3 different posterior fixation techniques for 2-level lumbar spinal disorders.Eight fresh-frozen human cadaver lumbar spines (4 from L-1 to L-5, 4 from L-1 to S-1) were tested by applying pure moments of ± 8 Nm. Each specimen was first tested intact, ... Read more >>

J Neurosurg Spine (Journal of neurosurgery. Spine)
[2016, 24(3):375-380]

Cited: 1 time

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A [4+1] Cyclative Capture Approach to 3H-Indole-N-oxides at Room Temperature by Rhodium(III)-Catalyzed CH Activation.

Yaxi Yang, Xuan Wang, Yuanchao Li, Bing Zhou,

The rhodium(III)-catalyzed [3+2] CH cyclization of aniline derivatives and internal alkynes represents a useful contribution to straightforward synthesis of indoles. However, there is no report on the more challenging synthesis of pharmaceutically important N-hydroxyindoles and 3H-indole-N-oxides. Reported herein is the first rhodium(III)-catalyzed [4+1] CH oxidative cyclization of nitrones with diazo ... Read more >>

Angew. Chem. Int. Ed. Engl. (Angewandte Chemie (International ed. in English))
[2015, 54(51):15400-15404]

Cited: 12 times

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Redox-neutral rhodium-catalyzed C-H functionalization of arylamine N-oxides with diazo compounds: primary C(sp(3))-H/C(sp(2))-H activation and oxygen-atom transfer.

Bing Zhou, Zhaoqiang Chen, Yaxi Yang, Wen Ai, Huanyu Tang, Yunxiang Wu, Weiliang Zhu, Yuanchao Li,

An unprecedented rhodium(III)-catalyzed regioselective redox-neutral annulation reaction of 1-naphthylamine N-oxides with diazo compounds was developed to afford various biologically important 1H-benzo[g]indolines. This coupling reaction proceeds under mild reaction conditions and does not require external oxidants. The only by-products are dinitrogen and water. More significantly, this reaction represents the first example ... Read more >>

Angew. Chem. Int. Ed. Engl. (Angewandte Chemie (International ed. in English))
[2015, 54(41):12121-12126]

Cited: 26 times

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