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Thermo-mechanical correlation in two-dimensional materials.

Yuan Cheng, Xing Wu, Zijian Zhang, Yao Sun, Yunshan Zhao, Yingyan Zhang, Gang Zhang,

Two-dimensional (2D) materials have received tremendous attention from the research community in the past decades, because of their numerous striking physical, chemical and mechanical properties and promising potential in a wide range of applications. This field is strongly interdisciplinary, requiring efficient integration of knowledge with different insights. In this review, ... Read more >>

Nanoscale (Nanoscale)
[2021, 13(3):1425-1442]

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A direct Z-scheme PtS2/arsenene van der Waals heterostructure with high photocatalytic water splitting efficiency.

Kai Ren, Wencheng Tang, Minglei Sun, Yongqing Cai, Yuan Cheng, Gang Zhang,

To overcome current serious energy and environmental issues, photocatalytic water splitting holds great promise because it requires only solar energy as an energy input to produce hydrogen. In this work, based on first-principle calculations, we studied the van der Waals heterostructure formed by PtS2 and arsenene (Are) monolayers that were ... Read more >>

Nanoscale (Nanoscale)
[2020, 12(33):17281-17289]

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Microstructural Regulation, Oxidation Resistance and Mechanical Properties of Cf/SiC/SiHfBOC Composites Prepared By Chemical Vapor Infiltration With Precursor Infiltration Pyrolysis

Yang LYU, Baihe DU, Guiqing CHEN, Guangdong ZHAO, Yuan CHENG, Shanbao ZHOU, Qingrong LV, Xinghong ZHANG, W.B. Han,

To further improve the oxidation resistance of PDC (Polymer Derived Ceramic) composites in harsh environments, C f /SiC/SiHfBOC composites were prepared by CVI (Chemical Vapor Infiltration) and PIP (Precursor Impregnation Pyrolysis) methods. The weight retention change, mechanical properties, and microstructure of C f /SiC/SiHfBOC before and after oxidation in air ... Read more >>

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Are medical record front page data suitable for risk adjustment in hospital performance measurement? Development and validation of a risk model of in-hospital mortality after acute myocardial infarction.

Chaoqun Wu, Danwei Zhang, Xueke Bai, Tiannan Zhou, Yongfei Wang, Zhenqiu Lin, Guangda He, Xi Li, ,

<h4>Objectives</h4>To develop a model of in-hospital mortality using medical record front page (MRFP) data and assess its validity in case-mix standardisation by comparison with a model developed using the complete medical record data.<h4>Design</h4>A nationally representative retrospective study.<h4>Setting</h4>Representative hospitals in China, covering 161 hospitals in modelling cohort and 156 hospitals in ... Read more >>

BMJ Open (BMJ open)
[2021, 11(4):e045053]

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Physiological clearance of amyloid-beta by the kidney and its therapeutic potential for Alzheimer's disease.

Ding-Yuan Tian, Yuan Cheng, Zhen-Qian Zhuang, Chen-Yang He, Qian-Guang Pan, Mao-Zhi Tang, Xue-Lian Hu, Ying-Ying Shen, Ye-Ran Wang, Si-Han Chen, Hao-Lun Sun, Pu-Yang Sun, Zhong-Yuan Yu, Dong-Yu Fan, Xian-Le Bu, Cheng-Rong Tan, Gui-Hua Zeng, Jun Wang, Hong-Wen Zhao, Yan-Jiang Wang,

Amyloid-β (Aβ) accumulation in the brain is a pivotal event in the pathogenesis of Alzheimer's disease (AD), and its clearance from the brain is impaired in sporadic AD. Previous studies suggest that approximately half of the Aβ produced in the brain is cleared by transport into the periphery. However, the ... Read more >>

Mol Psychiatry (Molecular psychiatry)
[2021, :]

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A community study of the risk for obstructive sleep apnea and respiratory inflammation in an adult Chinese population.

Cheng Zhang, Yuan Cheng, Liu Feng, Jing Ma, Guangfa Wang,

<b>Objectives</b>: We aimed to investigate the relationship between obstructive sleep apnea (OSA) risk and respiratory inflammation evaluated by the exhaled breath condensate (EBC) interleukin-6 (IL-6) and plasma surfactant protein-D (SP-D), based on the Berlin questionnaire (BQ) screening values in an adult, urban community in Beijing, China.<b>Methods</b>: Volunteers aged >40 years were ... Read more >>

Postgrad Med (Postgraduate medicine)
[2021, :1-10]

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Using PyC modified 3D carbon fiber to reinforce UHTC under low temperature sintering without pressure

Baihe DU, Yuan Cheng, Liancai XUN, Shuchang ZHANG, Jing TONG, Qingrong LV, Shanbao ZHOU, Ping Hu, Xinghong ZHANG,

To find the optimum balance between strength and toughness, as well as acquiring reliable thermal shock resistance and oxidation resistance, has always been the most concerned topic in the discussion of ultra-high temperature ceramic composites. Herein, PyC modified 3D carbon fiber is used to reinforce ultra-high temperature ceramic. The macroscopic ... Read more >>

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Targeting CXCR2 inhibits the progression of lung cancer and promotes therapeutic effect of cisplatin.

Yuan Cheng, Fei Mo, Qingfang Li, Xuejiao Han, Houhui Shi, Siyuan Chen, Yuquan Wei, Xiawei Wei,

<h4>Background</h4>Drug-resistance and severe side effects of chemotherapeutic agents result in unsatisfied survival of patients with lung cancer. CXCLs/CXCR2 axis plays an important role in progression of cancer including lung cancer. However, the specific anti-cancer mechanism of targeting CXCR2 remains unclear.<h4>Methods</h4>Immunohistochemical analysis of CXCR2 was performed on the microarray of tumor ... Read more >>

Mol Cancer (Molecular cancer)
[2021, 20(1):62]

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Diffuse Large B-cell Lymphoma Segmentation in PET-CT Images via Hybrid Learning for Feature Fusion.

Cheng Yuan, Miao Zhang, Xinyun Huang, Wei Xie, Xiaozhu Lin, Weili Zhao, Biao Li, Dahong Qian,

<h4>Purpose</h4>Diffuse large B-cell lymphoma (DLBCL) is an aggressive type of lymphoma with high mortality and poor prognosis that especially has a high incidence in Asia. Accurate segmentation of DLBCL lesions is crucial for clinical radiation therapy. However, manual delineation of DLBCL lesions is tedious and time-consuming. Automatic segmentation provides an ... Read more >>

Med Phys (Medical physics)
[2021, :]

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Hydrogen sulfide ameliorates high glucose-induced pro-inflammation factors in HT-22 cells: Involvement of SIRT1-mTOR/NF-κB signaling pathway.

Xinrui Li, Peiquan Yu, Yinghua Yu, Ting Xu, Jiao Liu, Yuan Cheng, Xia Yang, Xiaoying Cui, Cui Yin, Yi Liu,

Hyperglycemia-induced neuroinflammation promotes the progression of diabetic encephalopathy. Hydrogen sulfide (H<sub>2</sub>S) exerts anti-inflammatory and neuroprotective activities against neurodegenerative diseases. However, the effects of H<sub>2</sub>S on hyperglycemia-induced neuroinflammation has not been investigated in neurons. Herein, by using HT-22 neuronal cells, we found that high glucose decreased the levels of endogenous H<sub>2</sub>S ... Read more >>

Int Immunopharmacol (International immunopharmacology)
[2021, 95:107545]

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The complete chloroplast genome sequence of Nicotiana debneyi (Solanaceae).

Jianmin Zeng, Changjun Huang, Yong Liu, Cheng Yuan, Haiqin Yu, Biqing Song,

In present study, we report the complete chloroplast genome of <i>Nicotiana debneyi</i>, a species endemic to eastern coast of Australia. The total genome size of <i>N.debneyi</i> is 156,073 bp in length, containing a large single-copy region of 86,672 bp, a small single-copy region of 18,581 bp, and two inverted repeat regions of 25,410 bp. ... Read more >>

Mitochondrial DNA B Resour (Mitochondrial DNA. Part B, Resources)
[2021, 6(3):1042-1043]

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Feasibility and long-term safety of Ho:YAG laser lithotripsy in broncholithiasis patients.

Yuan Cheng, Guangfa Wang, Wei Zhang, Hong Zhang, Xi Wang,

<h4>Background</h4>Treatment of broncholithiasis is complex, especially in the case of a large or transbronchial broncholith. Holmium-yttrium aluminum garnet (Ho:YAG) laser lithotripsy may be a useful treatment in broncholithiasis; however, as it is not yet common practice, the optimal parameters are unknown.<h4>Methods</h4>We performed a single-center retrospective analysis of the clinical data ... Read more >>

BMC Pulm Med (BMC pulmonary medicine)
[2021, 21(1):81]

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Sanjie Yiliu Formula Inhibits Colorectal Cancer Growth by Suppression of Proliferation and Induction of Apoptosis.

Rong Zhu Tang, Zhang Zhi Li, Dan Hu, Fariha Kanwal, Cheng Bin Yuan, Muhammad Mustaqeem, Aima Iram Batool, Muhammad Fayyaz Ur Rehman,

Colorectal cancer (CRC) is one of the most common malignancies worldwide. As current therapies toward CRC, including chemotherapy and radiotherapy, pose limitations, such as multidrug resistance (MDR) as well as the intrinsic and potential cytotoxic effects, necessitating to find more effective treatment options with fewer side effects, traditional Chinese medicine ... Read more >>

ACS Omega (ACS omega)
[2021, 6(11):7761-7770]

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Correction to: Glomerulosclerosis predicts poor renal outcome in patients with idiopathic membranous nephropathy.

Cuimei Wei, Yongcheng He, Tong Li, Haofei Hu, Haiying Song, Dongli Qi, Yuan Cheng, Jia Chen, Mijie Guan, Xiaohua Xiao, Junyi Li,

Int Urol Nephrol (International urology and nephrology)
[2021, 53(3):601]

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Signaling through the type 2 cannabinoid receptor regulates the severity of acute and chronic graft-versus-host disease.

Cheng Yin Yuan, Vivian Zhou, Garrett Sauber, Todd Stollenwerk, Richard Komorowski, Alicia López, Rosa María Tolón, Julian Romero, Cecilia J Hillard, William R Drobyski,

Graft-versus-host disease (GVHD) pathophysiology is a complex interplay between cells that comprise the adaptive and innate arms of the immune system. Effective prophylactic strategies are therefore contingent upon approaches that address contributions from both immune cell compartments. In the current study, we examined the role of the type 2 cannabinoid ... Read more >>

Blood (Blood)
[2021, 137(9):1241-1255]

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Long-term prognostic factors of clinical success after interventional bronchoscopy in patients with scarring central airway stenosis.

Kunyan Sun, Hong Zhang, Wei Zhang, Yuan Cheng, Guangfa Wang,

<h4>Background</h4>Scarring central airway stenosis (SCAS) is a potentially life-threatening condition with debilitating symptoms. Interventional bronchoscopy is increasingly used to relieve symptoms in patients with SCAS, but recurrent stenosis is frequently observed. Little data exist on the long-term prognosis of interventional bronchoscopy for SCAS. We aimed to assess the prognostic factors ... Read more >>

BMC Pulm Med (BMC pulmonary medicine)
[2021, 21(1):73]

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Coding Recognition of the Dose-Effect Interdependence of Small Biomolecules Encrypted on Paired Chromatographic-Based Microassay Arrays

Yifeng Deng, Zhenpeng Lin, Yuan Cheng,

The discovery of new small molecular entities in diverse compounds suffers from the lack of a correlation recognition method between bioactivity and molecular characteristics such as DNA base pairing recognition in biomacromolecules. Here, by mapping a sample’s 2DHPTLC fingerprint into microplates to create paired chromatographic-based microassay arrays, on which the ... Read more >>

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Co-amplification of Genes in Chromosome 8q24: a Robust Prognostic Marker in Hepatocellular Carcinoma

Yuan Cheng, Yongjian Zheng, Cheng Zhang, Shunjun Fu, Guolin He, Lei Cai, Ling Qiu, Huakun Huang, Qunhui Chen, Wenzhuan Xie, Tingting Chen, Mengli Huang, Yuezong Bai, Mingxin Pan,

<h4>Background: </h4> Hepatocellular carcinoma (HCC) is one of the majorcause of cancer related deaths worldwide, due tohigh 5 yearpostoperativerecurrence rate and individualheterogeneity.Thus, prognostic modelhas dramaticallyurgently neededon HCCin recent years.Serval research have reported that copy number amplificationof the 8q24 chromosomalregion is associated with lowsurvival in many cancers. The objectiveof this study ... Read more >>

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Self-Assembled DNA Nanostructure as a Carrier for Targeted siRNA Delivery in Glioma Cells.

Yanghao Zhou, Qiang Yang, Feng Wang, Zunjie Zhou, Jing Xu, Si Cheng, Yuan Cheng,

<h4>Introduction</h4>RNA interference is a promising therapy in glioma treatment. However, the application of RNA interference has been limited in glioma therapy by RNA instability and the lack of tumor targeting. Here, we report a novel DNA tetrahedron, which can effectively deliver small interfering RNA to glioma cells and induce apoptosis.<h4>Methods</h4>siRNA, ... Read more >>

Int J Nanomedicine (International journal of nanomedicine)
[2021, 16:1805-1817]

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Impact of climate change on "evaporation paradox" in province of Jiangsu in southeastern China.

Mengsheng Qin, Yuan Zhang, Shiquan Wan, Yuan Yue, Yuan Cheng, Bo Zhang,

Contrary to the common expectation that the reference evapotranspiration (ETo), which is an indicator of the atmospheric evaporation capability, increases in warming climate, the decline of the ETo has been reported worldwide, and this contradiction between the expected increasing ETo and the observed decreasing one is now termed the "evaporation ... Read more >>

PLoS One (PloS one)
[2021, 16(2):e0247278]

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A multicenter clinical study: personalized medication for advanced gastrointestinal carcinomas with the guidance of Patient-Derived Tumor Xenograft (PDTX)

Yuan Cheng, Shu-kui Qin, Jin Li, Guang-hai Dai, Bai-yong Shen, Jie-er Shen, Yi Ba, Xin-bo Wang, Ye Xu, Lin Zhou, Ke-feng Ding, Yan-ru Qin, Shu-jun Yang, Yan-ping Zhu,

<h4>Background: </h4> Establish patient-derived tumor xenograft (PDTX) from advanced GICs and assess the clinical value and applicability of PDTX for the treatment of advanced GICs. Method: Patients with advanced GICs were enrolled in a registered multi-center clinical study (ChiCTR-OOC-17012731). The performance of PDTX were evaluated includes: analyzing factors that affect ... Read more >>

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Activin A activation drives renal fibrosis through the STAT3 signaling pathway.

Cheng Yuan, Lihua Ni, Xiaoyan Wu,

The present study investigated whether TGF-β1 promotes fibrotic changes in HK-2 cells through the Activin A and STAT3 signaling pathways in vitro. Bioinformatics analysis of microarray profiles (GSE20247 and GSE23338) and a protein-protein interaction (PPI) analysis were performed to select hub genes. For the in vitro study, HK-2 cells were ... Read more >>

Int J Biochem Cell Biol (The international journal of biochemistry & cell biology)
[2021, 134:105950]

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Overexpression of two CDPKs from wild Chinese grapevine enhances powdery mildew resistance in Vitis vinifera and Arabidopsis.

Yang Hu, Yuan Cheng, Xuena Yu, Jie Liu, Lushan Yang, Yurong Gao, Guihua Ke, Min Zhou, Bo Mu, Shunyuan Xiao, Yuejin Wang, Ying-Qiang Wen,

Calcium-dependent protein kinases (CDPKs) play vital roles in metabolic regulations and stimuli responses in plants. However, little is known about their function in grapevine. Here, we report that VpCDPK9 and VpCDPK13, two paralogous CDPKs from Vitis pseudoreticulata accession Baihe-35-1, appear to positively regulate powdery mildew resistance. The transcription of them ... Read more >>

New Phytol (The New phytologist)
[2021, :]

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High expression of vinculin predicts poor prognosis and distant metastasis and associates with influencing tumor-associated NK cell infiltration and epithelial-mesenchymal transition in gastric cancer.

Huafu Li, Chunming Wang, Linxiang Lan, Axel Behrens, Mona Tomaschko, Josue Ruiz, Qiao Su, Guangying Zhao, Cheng Yuan, Xing Xiao, Bo Li, Leping Yan, Wang Wu, Wuguo Li, Junzong Chen, Yulong He, Changhua Zhang,

In the process of epithelial-mesenchymal transition (EMT), epithelial cancer cells transdifferentiate into mesenchymal-like cells with high motility and aggressiveness, resulting in the spread of tumor cells. Immune cells and inflammation in the tumor microenvironment are the driving factors of EMT, but few studies have explored the core targets of the ... Read more >>

Aging (Albany NY) (Aging)
[2021, 13(4):5197-5225]

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Co-infection of influenza A virus and SARS-CoV-2: A retrospective cohort study.

Yuan Cheng, Jing Ma, He Wang, Xi Wang, Zhanwei Hu, Haichao Li, Hong Zhang, Xinmin Liu,

The coronavirus 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread across the world and is responsible for over 1,686,267 deaths worldwide. Co-infection with influenza A virus (IFV-A) during the upcoming flu season may complicate diagnosis and treatment of COVID-19. Little is known about epidemiology ... Read more >>

J Med Virol (Journal of medical virology)
[2021, 93(5):2947-2954]

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