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Author Yu Jing Fang

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Educational level and colorectal cancer risk: the mediating roles of lifestyle and dietary factors.

Lei Li, Yu-Jing Fang, Alinuer Abulimiti, Chu-Yi Huang, Kai-Yan Liu, Yu-Ming Chen, Cai-Xia Zhang,

<h4>Objective</h4>The association between the educational level and colorectal cancer risk was controversial in developed countries and evidence was limited in Chinese population. This study aimed to investigate the association between the educational level and colorectal cancer risk in Guangdong Province, China.<h4>Methods</h4>From July 2010 to April 2019, 2502 newly diagnosed colorectal ... Read more >>

Eur J Cancer Prev (European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP))
[2021, :]

Cited: 0 times

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Dietary Polyamines Intake and Risk of Colorectal Cancer: A Case-Control Study.

Chu-Yi Huang, Yu-Jing Fang, Alinuer Abulimiti, Xia Yang, Lei Li, Kai-Yan Liu, Xin Zhang, Xiao-Li Feng, Yu-Ming Chen, Cai-Xia Zhang,

Polyamines (including putrescine, spermidine, and spermine) are small, cationic molecules that are necessary for cell proliferation and differentiation. Few studies have examined the association of dietary polyamines intake with colorectal cancer risk. The aim of this study was to evaluate total polyamines, putrescine, spermidine, and spermine intake in relation to ... Read more >>

Nutrients (Nutrients)
[2020, 12(11):]

Cited: 0 times

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Interactions Between Vitamin D and Calcium Intake, Vitamin D Receptor Genetic Polymorphisms, and Colorectal Cancer Risk.

Xin Zhang, Yu-Jing Fang, Xiao-Li Feng, Alinuer Abulimiti, Chu-Yi Huang, Hong Luo, Cai-Xia Zhang,

<h4>Background</h4>Vitamin D has anticarcinogenic properties and acts through vitamin D receptor (VDR) to carry out its functions.<h4>Aims</h4>This study explored the independent and combined effects of dietary vitamin D and calcium, and VDR genetic polymorphisms on colorectal cancer risk in a Chinese population.<h4>Methods</h4>This ongoing case-control study recruited 488 cases with histologically ... Read more >>

Dig Dis Sci (Digestive diseases and sciences)
[2021, 66(6):1895-1905]

Cited: 2 times

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Association between Dietary Zinc and Selenium Intake, Oxidative Stress-Related Gene Polymorphism, and Colorectal Cancer Risk in Chinese Population - A Case-Control Study.

Hong Luo, Yu-Jing Fang, Xin Zhang, Xiao-Li Feng, Nai-Qi Zhang, Alinuer Abulimiti, Chu-Yi Huang, Cai-Xia Zhang,

Zinc and selenium may protect against colorectal cancer (CRC) progression through their anti-oxidative effects. This study examined the independent and combined effect of dietary zinc and selenium intake, and polymorphisms of the oxidative stress-related genes (superoxide dismutase 1, superoxide dismutase 2, glutathione peroxidase, and catalase) on CRC risk in a ... Read more >>

Nutr Cancer (Nutrition and cancer)
[2020, :1-10]

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Dietary B vitamin and methionine intakes and risk for colorectal cancer: a case-control study in China.

Chu-Yi Huang, Alinuer Abulimiti, Xin Zhang, Xiao-Li Feng, Hong Luo, Yu-Ming Chen, Yu-Jing Fang, Cai-Xia Zhang,

B vitamins (including folate, vitamin B2, vitamin B6 and vitamin B12) and methionine are essential for methylation reactions, nucleotide synthesis, DNA stability and DNA repair. However, epidemiological evidence among Chinese populations is limited. The objective of this study was to evaluate B vitamins and methionine in relation to colorectal cancer ... Read more >>

Br J Nutr (The British journal of nutrition)
[2020, 123(11):1277-1289]

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Higher intakes of dietary vitamin D, calcium and dairy products are inversely associated with the risk of colorectal cancer: a case-control study in China.

Xin Zhang, Yu-Jing Fang, Xiao-Li Feng, Alinuer Abulimiti, Chu-Yi Huang, Hong Luo, Nai-Qi Zhang, Yu-Ming Chen, Cai-Xia Zhang,

The effects of dietary vitamin D, Ca and dairy products intakes on colorectal cancer risk remain controversial. The present study investigated the association between these dietary intakes and the risk of colorectal cancer in Guangdong, China. From July 2010 to December 2018, 2380 patients with colorectal cancer and 2389 sex- ... Read more >>

Br J Nutr (The British journal of nutrition)
[2020, 123(6):699-711]

Cited: 4 times

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The Dietary Inflammatory Index Is Positively Associated with Colorectal Cancer Risk in a Chinese Case-Control Study.

Alinuer Abulimiti, Xin Zhang, Nitin Shivappa, James R Hébert, Yu-Jing Fang, Chu-Yi Huang, Xiao-Li Feng, Yu-Ming Chen, Cai-Xia Zhang,

Diet may modulate chronic inflammation. The aim of this study is to investigate whether the dietary inflammatory index (DII®) was associated with the risk of colorectal cancer in a Chinese population. A case-control study was conducted from July 2010 to April 2019, in Guangzhou, China. A total of 2502 eligible ... Read more >>

Nutrients (Nutrients)
[2020, 12(1):]

Cited: 1 time

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Dietary and serum vitamins A and E and colorectal cancer risk in Chinese population: a case-control study.

Hong Luo, Yu-Jing Fang, Min-Shan Lu, Zhi-Zhong Pan, Jing Huang, Yu-Ming Chen, Cai-Xia Zhang,

The effect of vitamin A (VA) and vitamin E (VE) on colorectal cancer (CRC) risk is controversial. The aim of this study is to examine the association between serum concentrations and dietary intakes of VA and VE and the risk of CRC in Guangdong, China. A total of 535 cases ... Read more >>

Eur J Cancer Prev (European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP))
[2019, 28(4):268-277]

Cited: 2 times

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Different forms and sources of iron in relation to colorectal cancer risk: a case-control study in China.

Hong Luo, Nai-Qi Zhang, Jing Huang, Xin Zhang, Xiao-Li Feng, Zhi-Zhong Pan, Yu-Ming Chen, Yu-Jing Fang, Cai-Xia Zhang,

Few studies have examined the association of various types of Fe with colorectal cancer risk. The aim of this study was to investigate different forms and sources of Fe in relation to colorectal cancer risk in a Chinese population. A total of 2138 patients with colorectal cancer and 2144 sex- ... Read more >>

Br J Nutr (The British journal of nutrition)
[2019, 121(7):735-747]

Cited: 2 times

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Dihydroartemisinin inhibits colon cancer cell viability by inducing apoptosis through up-regulation of PPARγ expression.

Zhen-Hai Lu, Jian-Hong Peng, Rong-Xin Zhang, Fulong Wang, Hui-Ping Sun, Yu-Jing Fang, De-Sen Wan, Zhi-Zhong Pan,

The present study was aimed to investigate the effect of dihydroartemisinin on the colon cancer cell proliferation and apoptosis. The results from MTT assay revealed a concentration and time dependent relation between the inhibition of SW 948 cell viability and dihydroartemisinin addition. The viability of SW 948 cells was reduced ... Read more >>

Saudi J Biol Sci (Saudi journal of biological sciences)
[2018, 25(2):372-376]

Cited: 4 times

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Carbohydrate, dietary glycaemic index and glycaemic load, and colorectal cancer risk: a case-control study in China.

Jing Huang, Yu-Jing Fang, Ming Xu, Hong Luo, Nai-Qi Zhang, Wu-Qing Huang, Zhi-Zhong Pan, Yu-Ming Chen, Cai-Xia Zhang,

A carbohydrate-rich diet results in hyperglycaemia and hyperinsulinaemia; it may further induce the carcinogenesis of colorectal cancer. However, epidemiological evidence among Chinese population is quite limited. The aim of this study was to investigate total carbohydrate, non-fibre carbohydrate, total fibre, starch, dietary glycaemic index (GI) and glycaemic load (GL) in ... Read more >>

Br J Nutr (The British journal of nutrition)
[2018, 119(8):937-948]

Cited: 5 times

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CD169 identifies an activated CD8(+) T cell subset in regional lymph nodes that predicts favorable prognosis in colorectal cancer patients.

Jiali Zhang, Jing Xu, Rong-Xin Zhang, Yi Zhang, Qing-Jian Ou, Jin-Qing Li, Ze-Zhou Jiang, Xiao-Jun Wu, Yu-Jing Fang, Limin Zheng,

<h4>Purpose</h4>CD169 was first identified on macrophages (Mϕ) and linked to antigen presentation. Here, we showed CD169 expression on some CD8(+) T lymphocytes in regional lymph nodes (LNs) and investigated the function and clinical relevance of CD169(+)CD8(+) T cells in tumor-draining LNs of colorectal cancer (CRC) patients.<h4>Experimental design</h4>Fresh tumor-draining LN tissues ... Read more >>

Oncoimmunology (Oncoimmunology)
[2016, 5(7):e1177690]

Cited: 5 times

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Endocrine therapy inhibits proliferation and migration, promotes apoptosis and suppresses survivin protein expression in colorectal cancer cells.

Qing-Jian Ou, Xiao-Jun Wu, Jian-Hong Peng, Rong-Xin Zhang, Zhen-Hai Lu, Wu Jiang, Lin Zhang, Zhi-Zhong Pan, De-Sen Wan, Yu-Jing Fang,

The majority of colorectal cancers (CRCs) are hormone‑dependent. Thus, endocrine therapy has become an attractive strategy to treat CRC. The aim of the present study was to investigate the inhibitory effect of combined tamoxifen (TAM) plus β‑estradiol (E2) treatment on human DLD‑1 CRC cells. The human DLD‑1 CRC cell line ... Read more >>

Mol Med Rep (Molecular medicine reports)
[2017, 16(5):5769-5778]

Cited: 0 times

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Programmed death-ligand 1 expression correlates with diminished CD8+ T cell infiltration and predicts poor prognosis in anal squamous cell carcinoma patients.

Yu-Jie Zhao, Wei-Peng Sun, Jian-Hong Peng, Yu-Xiang Deng, Yu-Jing Fang, Jun Huang, Hui-Zhong Zhang, De-Sen Wan, Jun-Zhong Lin, Zhi-Zhong Pan,

Objective:Increased expression of programmed death-ligand 1 (PD-L1) on tumor cells can be found in various malignancies; however, very limited information is known about its role in anal squamous cell carcinoma (ASCC). This study explored PD-L1 expression in ASCC patients and its association with patients' clinicopathological features, CD8+ T cell infiltration, ... Read more >>

Cancer Manag Res (Cancer management and research)
[2018, 10:1-11]

Cited: 8 times

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Serum carotenoids and colorectal cancer risk: A case-control study in Guangdong, China.

Jing Huang, Min-Shan Lu, Yu-Jing Fang, Ming Xu, Wu-Qing Huang, Zhi-Zhong Pan, Yu-Ming Chen, Cai-Xia Zhang,

<h4>Scope</h4>Previous epidemiological studies on the association between circulating carotenoids and the risk of colorectal cancer drew inconclusive conclusions. This study aimed to examine serum carotenoids in relation to colorectal cancer risk in a Chinese population.<h4>Methods and results</h4>One case-control study beginning from July 2010, consecutively recruited 538 eligible colorectal cancer cases ... Read more >>

Mol Nutr Food Res (Molecular nutrition & food research)
[2017, 61(10):]

Cited: 4 times

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Association between phytosterol intake and colorectal cancer risk: a case-control study.

Jing Huang, Ming Xu, Yu-Jing Fang, Min-Shan Lu, Zhi-Zhong Pan, Wu-Qing Huang, Yu-Ming Chen, Cai-Xia Zhang,

A study in rodent models showed that phytosterols protected against colon carcinogenesis, probably by inhibiting dysregulated cell cycle progression and inducing cellular apoptosis. However, epidemiological studies on the relationship between phytosterols and colorectal cancer risk are quite limited. The aim of this study was to investigate dietary phytosterol intake in ... Read more >>

Br J Nutr (The British journal of nutrition)
[2017, 117(6):839-850]

Cited: 4 times

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A scoring system based on artificial neural network for predicting 10-year survival in stage II A colon cancer patients after radical surgery.

Jian-Hong Peng, Yu-Jing Fang, Cai-Xia Li, Qing-Jian Ou, Wu Jiang, Shi-Xun Lu, Zhen-Hai Lu, Pei-Xing Li, Jing-Ping Yun, Rong-Xin Zhang, Zhi-Zhong Pan, De Sen Wan,

Nearly 20% patients with stage II A colon cancer will develop recurrent disease post-operatively. The present study aims to develop a scoring system based on Artificial Neural Network (ANN) model for predicting 10-year survival outcome. The clinical and molecular data of 117 stage II A colon cancer patients from Sun ... Read more >>

Oncotarget (Oncotarget)
[2016, 7(16):22939-22947]

Cited: 8 times

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Flavonoid intake from vegetables and fruits is inversely associated with colorectal cancer risk: a case-control study in China.

Ming Xu, Yu-Ming Chen, Jing Huang, Yu-Jing Fang, Wu-Qing Huang, Bo Yan, Min-Shan Lu, Zhi-Zhong Pan, Cai-Xia Zhang,

Flavonoids may play an important role in the protective effects of vegetables, fruits and tea against colorectal cancer. However, associations between flavonoids and colorectal cancer risk are inconsistent, and a few studies have evaluated the effect of flavonoids from different dietary sources separately. This study aimed to evaluate associations of ... Read more >>

Br J Nutr (The British journal of nutrition)
[2016, 116(7):1275-1287]

Cited: 18 times

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Higher freshwater fish and sea fish intake is inversely associated with colorectal cancer risk among Chinese population: a case-control study.

Ming Xu, Yu-Jing Fang, Yu-Ming Chen, Min-Shan Lu, Zhi-Zhong Pan, Bo Yan, Xiao Zhong, Cai-Xia Zhang,

The association between specific fish intake and colorectal cancer risk remains controversial. This study aimed to examine the association between specific fish intake and colorectal cancer risk in Chinese population in a large case control study. During July 2010 to November 2014, 1189 eligible colorectal cancer cases and 1189 frequency-matched ... Read more >>

Sci Rep (Scientific reports)
[2015, 5:12976]

Cited: 4 times

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High consumption of vegetable and fruit colour groups is inversely associated with the risk of colorectal cancer: a case-control study.

Wei-Ping Luo, Yu-Jing Fang, Min-Shan Lu, Xiao Zhong, Yu-Ming Chen, Cai-Xia Zhang,

The colour of the edible portion of vegetables and fruit reflects the presence of specific micronutrients and phytochemicals. No existing studies have examined the relationship between the intake of vegetable and fruit colour groups and the risk of colorectal cancer. The present study, therefore, aimed to investigate these associations in ... Read more >>

Br J Nutr (The British journal of nutrition)
[2015, 113(7):1129-1138]

Cited: 12 times

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Choline and betaine intake and colorectal cancer risk in Chinese population: a case-control study.

Min-Shan Lu, Yu-Jing Fang, Zhi-Zhong Pan, Xiao Zhong, Mei-Chun Zheng, Yu-Ming Chen, Cai-Xia Zhang,

<h4>Background</h4>Few studies have examined the association of choline and betaine intake with colorectal cancer risk, although they might play an important role in colorectal cancer development because of their role as methyl donors. The aim of this study was to examine the relationship between consumption of choline and betaine and ... Read more >>

PLoS One (PloS one)
[2015, 10(3):e0118661]

Cited: 8 times

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Higher intake of carotenoid is associated with a lower risk of colorectal cancer in Chinese adults: a case-control study.

Min-Shan Lu, Yu-Jing Fang, Yu-Ming Chen, Wei-Ping Luo, Zhi-Zhong Pan, Xiao Zhong, Cai-Xia Zhang,

<h4>Purpose</h4>The associations between specific carotenoid intake and colorectal cancer risk remain inconsistent. The aim of this study was to examine the association between specific dietary carotenoid intake with colorectal cancer risk in Chinese adults.<h4>Method</h4>From July 2010 to October 2013, 845 eligible colorectal cancer cases and 845 frequency-matched controls (age and ... Read more >>

Eur J Nutr (European journal of nutrition)
[2015, 54(4):619-628]

Cited: 14 times

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Dietary fiber and fiber fraction intakes and colorectal cancer risk in Chinese adults.

Xiao Zhong, Yu-Jing Fang, Zhi-Zhong Pan, Min-Shan Lu, Mei-Chun Zheng, Yu-Ming Chen, Cai-Xia Zhang,

Few studies have been conducted in Chinese adults to investigate the effect of fiber intake on colorectal cancer risk. The present study aimed to examine the associations of dietary fiber and fiber fraction intakes with colorectal cancer risk in Chinese adults. A total of 613 cases with colorectal cancer were ... Read more >>

Nutr Cancer (Nutrition and cancer)
[2014, 66(3):351-361]

Cited: 12 times

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Hospital-based colorectal cancer survival trend of different tumor locations from 1960s to 2000s.

Yu-Jing Fang, Xiao-Jun Wu, Qian Zhao, Li-Ren Li, Zhen-Hai Lu, Pei-Rong Ding, Rong-Xin Zhang, Ling-Heng Kong, Fu-Long Wang, Jun-Zhong Lin, Gong Chen, Zhi-Zhong Pan, De-Sen Wan,

<h4>Background</h4>Our aim is to explore the trend of association between the survival rates of colorectal cancer (CRC) and the different clinical characteristics in patients registered from 1960s to 2000s. We hypothesized that the survival rate of CRC increases over time and varies according to anatomic subsites.<h4>Methods</h4>Information from a total of ... Read more >>

PLoS One (PloS one)
[2013, 8(9):e73528]

Cited: 18 times

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Dietary fat, fatty acid intakes and colorectal cancer risk in Chinese adults: a case-control study.

Xiao Zhong, Yu-Jing Fang, Zhi-Zhong Pan, Bin Li, Lian Wang, Mei-Chun Zheng, Yu-Ming Chen, Cai-Xia Zhang,

The associations between dietary fat intakes and the risk of colorectal cancer have been examined in many epidemiological studies, but the results have remained inconsistent. This study aimed to examine the associations of total fat and fatty acid intakes with the risk of colorectal cancer in Guangzhou, China. A case-control ... Read more >>

Eur J Cancer Prev (European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP))
[2013, 22(5):438-447]

Cited: 14 times

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