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Author Yoshinori Doi

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Prediction model for hepatocellular carcinoma occurrence in patients with hepatitis C in the era of direct-acting anti-virals.

Yuki Tahata, Ryotaro Sakamori, Ryoko Yamada, Takahiro Kodama, Hayato Hikita, Hideki Hagiwara, Yasuharu Imai, Naoki Hiramatsu, Shinji Tamura, Keiji Yamamoto, Masahide Oshita, Kazuyoshi Ohkawa, Taizo Hijioka, Hiroyuki Fukui, Toshifumi Ito, Yoshinori Doi, Yukinori Yamada, Takayuki Yakushijin, Yuichi Yoshida, Tomohide Tatsumi, Tetsuo Takehara, ,

<h4>Background</h4>Several factors associated with hepatocellular carcinoma (HCC) occurrence after sustained virological response (SVR) in patients with hepatitis C have been reported. However, few validation studies have been performed in the era of direct-acting anti-virals (DAAs).<h4>Aims</h4>To develop a prediction model for HCC occurrence after DAA-mediated SVR and validate its usefulness.<h4>Methods</h4>We analysed ... Read more >>

Aliment Pharmacol Ther (Alimentary pharmacology & therapeutics)
[2021, :]

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Clinical significance of new-onset atrial fibrillation in patients with hypertrophic cardiomyopathy.

Toru Kubo, Yuichi Baba, Yuri Ochi, Takayoshi Hirota, Naohito Yamasaki, Kazuya Kawai, Katsuhito Yamamoto, Fumiaki Kondo, Kanji Bando, Eisuke Yamada, Takashi Furuno, Toshikazu Yabe, Yoshinori L Doi, Hiroaki Kitaoka,

<h4>Aims</h4>There is limited information about the clinical significance of atrial fibrillation (AF), particularly new-onset AF, in patients with hypertrophic cardiomyopathy (HCM) in a community-based patient cohort. This study was carried out to clarify the prevalence and prognostic impact of AF in Japanese HCM patients.<h4>Methods and results</h4>In 2004, we established a ... Read more >>

ESC Heart Fail (ESC heart failure)
[2021, :]

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Progressive deterioration of frailty is associated with poor outcomes in patients with transthyretin cardiac amyloidosis.

Makoto Takahashi, Nao Okamoto, Koji Nishida, Yoko Nakaoka, Ryu-Ichiro Imai, Shu-Ichi Seki, Toru Kubo, Naohito Yamasaki, Hiroaki Kitaoka, Sho-Ichi Kubokawa, Kazuya Kawai, Naohisa Hamashige, Yoshinori Doi,

Geriatr Gerontol Int (Geriatrics & gerontology international)
[2021, 21(10):967-969]

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JCS/JHFS 2018 Guideline on the Diagnosis and Treatment of Cardiomyopathies.

Hiroaki Kitaoka, Hiroyuki Tsutsui, Toru Kubo, Tomomi Ide, Taishiro Chikamori, Keiichi Fukuda, Noboru Fujino, Taiki Higo, Mitsuaki Isobe, Chizuko Kamiya, Seiya Kato, Yasuki Kihara, Koichiro Kinugawa, Shintaro Kinugawa, Shigetoyo Kogaki, Issei Komuro, Nobuhisa Hagiwara, Minoru Ono, Yuichiro Maekawa, Shigeru Makita, Yoshiro Matsui, Shouji Matsushima, Yasushi Sakata, Yoshiki Sawa, Wataru Shimizu, Kunihiko Teraoka, Miyuki Tsuchihashi-Makaya, Hatsue Ishibashi-Ueda, Masafumi Watanabe, Michihiro Yoshimura, Arata Fukusima, Satoshi Hida, Shungo Hikoso, Teruhiko Imamura, Hiroko Ishida, Makoto Kawai, Toshiro Kitagawa, Takashi Kohno, Satoshi Kurisu, Yoji Nagata, Makiko Nakamura, Hiroyuki Morita, Hitoshi Takano, Tsuyoshi Shiga, Yasuyoshi Takei, Shinsuke Yuasa, Teppei Yamamoto, Tetsu Watanabe, Takashi Akasaka, Yoshinori Doi, Takeshi Kimura, Masafumi Kitakaze, Masami Kosuge, Morimasa Takayama, Hitonobu Tomoike, ,

Circ J (Circulation journal : official journal of the Japanese Circulation Society)
[2021, 85(9):1590-1689]

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Importance of Paroxysmal Atrial Fibrillation and Sex Differences in the Prevention of Embolic Stroke in Hypertrophic Cardiomyopathy.

Junya Komatsu, Ryu-Ichiro Imai, Yoko Nakaoka, Koji Nishida, Shu-Ichi Seki, Toru Kubo, Naohito Yamasaki, Hiroaki Kitaoka, Sho-Ichi Kubokawa, Kazuya Kawai, Naohisa Hamashige, Yoshinori L Doi,

<b><i>Background:</i></b> Although atrial fibrillation (AF) is a well-known risk factor for embolic stroke in hypertrophic cardiomyopathy (HCM), there is a paucity of information derived from HCM patients who have experienced embolic stroke. <b><i>Methods and Results:</i></b> From 141 consecutive HCM patients who had been hospitalized between 2000 and 2018, the clinical characteristics and ... Read more >>

Circ Rep (Circulation reports)
[2021, 3(5):273-278]

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Clinical course of hepatitis C virus-positive patients with decompensated liver cirrhosis in the era of direct-acting antiviral treatment.

Kazuki Maesaka, Ryotaro Sakamori, Ryoko Yamada, Yuki Tahata, Masahide Oshita, Hideki Hagiwara, Mitsuru Sakakibara, Shinji Tamura, Naoki Hiramatsu, Masami Inada, Sadaharu Iio, Toshifumi Ito, Takayuki Yakushijin, Yoshinori Doi, Takahiro Kodama, Hayato Hikita, Tomohide Tatsumi, Tetsuo Takehara,

<h4>Aim</h4>The aim of the present study was to investigate the clinical course in hepatitis C virus (HCV)-positive patients with decompensated liver cirrhosis after direct-acting antivirals (DAAs) have been used for HCV infection.<h4>Methods</h4>This multicenter study prospectively analyzed a registered cohort composed of 73 HCV-positive patients with decompensated cirrhosis who attended our ... Read more >>

Hepatol Res (Hepatology research : the official journal of the Japan Society of Hepatology)
[2021, 51(5):517-527]

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A Validation Study of the Mayo Clinic Phenotype-Based Genetic Test Prediction Score for Japanese Patients With Hypertrophic Cardiomyopathy.

Toshihiro Moriki, Toru Kubo, Kenta Sugiura, Yuri Ochi, Yuichi Baba, Takayoshi Hirota, Naohito Yamasaki, Akinori Kimura, Yoshinori L Doi, Hiroaki Kitaoka,

<h4>Background</h4>Hypertrophic cardiomyopathy (HCM) is a primary myocardial disorder with an autosomal-dominant disorder mainly caused by mutations in sarcomere genes. Recently, a phenotype-based genetic test prediction score for patients with HCM was introduced by Mayo Clinic. The genotype score was derived on the basis of the predictive effect of 6 clinical ... Read more >>

Circ J (Circulation journal : official journal of the Japanese Circulation Society)
[2021, 85(5):669-674]

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Elevation of high-sensitivity cardiac troponin T and left ventricular remodelling in hypertrophic cardiomyopathy.

Toru Kubo, Yuri Ochi, Yuichi Baba, Kenta Sugiura, Asa Takahashi, Takayoshi Hirota, Shigeo Yamanaka, Naohito Yamasaki, Yoshinori L Doi, Hiroaki Kitaoka,

<h4>Aims</h4>Hypertrophic cardiomyopathy (HCM) is generally associated with mild disability and normal life expectancy. On the other hand, once the end-stage phase of HCM characterized by left ventricular (LV) ejection fraction < 50% is established, patients with this subtype have a poor prognosis. This study clarifies the clinical parameters associated with progression to ... Read more >>

ESC Heart Fail (ESC heart failure)
[2020, :]

Cited: 3 times

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Lifelong Clinical Impact of the Presence of Sarcomere Gene Mutation in Japanese Patients With Hypertrophic Cardiomyopathy.

Yasuteru Nakashima, Toru Kubo, Kenta Sugiura, Yuri Ochi, Asa Takahashi, Yuichi Baba, Takayoshi Hirota, Naohito Yamasaki, Akinori Kimura, Yoshinori L Doi, Hiroaki Kitaoka,

<h4>Background</h4>Hypertrophic cardiomyopathy (HCM) is mainly caused by mutations in sarcomere genes. Regarding the clinical implications of genetic information, little is known about the lifelong clinical effect of sarcomere mutations in Japanese HCM patients.Methods and Results:We studied 211 consecutive Japanese patients with HCM who had agreed to genetic testing between 2003 and 2013. ... Read more >>

Circ J (Circulation journal : official journal of the Japanese Circulation Society)
[2020, 84(10):1846-1853]

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A Novel Disease Entity in Search of Its Own Identity - Takotsubo Syndrome. Is It Really "Cardiomyopathy"?

Yoshinori L Doi, Toru Kubo, Hiroaki Kitaoka,

<b><i>Background:</i></b> The term "takotsubo cardiomyopathy" is commonly used in clinical practice. However, there is conceptual problem with the term "cardiomyopathy" in this context because "cardiomyopathy" implies a primary and chronic myocardial disease of unknown etiology. In this study we reviewed the literature related to takotsubo cardiomyopathy to investigate whether it ... Read more >>

Circ Rep (Circulation reports)
[2020, 2(8):446-448]

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Premature Onset Aortic Stenosis in Systemic Sclerosis: A Report of a Series of Cases.

Ayaka Machida, Takashi Funaki, Koji Nishida, Ryu-Ichiro Imai, Yoko Nakaoka, Shu-Ichi Seki, Yu-Ichi Baba, Toru Kubo, Naohito Yamasaki, Hiroaki Kitaoka, Sho-Ichi Kubokawa, Hiroshi Sakaeda, Kazuya Kawai, Naohisa Hamashige, Yoshinori Doi,

Although cardiovascular involvement is a well-known complication correlated with a poor prognosis in patients with systemic sclerosis, there are few reports on valvular heart disease. Forty patients with systemic sclerosis were retrospectively analyzed. Valvular heart disease was found in six patients, five of whom had severe tri-leaflet aortic stenosis. Three ... Read more >>

Intern Med (Internal medicine (Tokyo, Japan))
[2020, 59(24):3177-3181]

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Sudden Cardiac Death-Relevant Events of Hypertrophic Cardiomyopathy in a Regional Japanese Cohort - Results From the Kochi RYOMA Study.

Toru Kubo, Yuichi Baba, Yuri Ochi, Asa Takahashi, Takayoshi Hirota, Naohito Yamasaki, Naohisa Hamashige, Katsuhito Yamamoto, Fumiaki Kondo, Kanji Bando, Eisuke Yamada, Takashi Furuno, Toshikazu Yabe, Yoshinori L Doi, Hiroaki Kitaoka,

<b><i>Background:</i></b> Sudden cardiac death (SCD) is a most devastating complication of hypertrophic cardiomyopathy (HCM). The aim of this study was to clarify the clinical features of HCM in patients who experienced SCD-relevant events in an aged Japanese community. <b><i>Methods and Results:</i></b> In 2004, we established a cardiomyopathy registration network in Kochi Prefecture, ... Read more >>

Circ Rep (Circulation reports)
[2020, 2(8):433-439]

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Pre-existing minor variants with NS5A L31M/V-Y93H double substitution are closely linked to virologic failure with asunaprevir plus daclatasvir treatment for genotype 1b hepatitis C virus infection.

Naoki Morishita, Ryotaro Sakamori, Tomomi Yamada, Yugo Kai, Yuki Tahata, Ayako Urabe, Ryoko Yamada, Takahiro Kodama, Hayato Hikita, Yoshinori Doi, Shinji Tamura, Hideki Hagiwara, Yasuharu Imai, Sadaharu Iio, Tomohide Tatsumi, Tetsuo Takehara,

<h4>Background</h4>L31 and Y93 in the NS5A region of the hepatitis C virus (HCV) are the most important substitution positions associated with resistance to direct-acting antiviral (DAA) treatment.<h4>Methods</h4>We analyzed the frequency of NS5A L31M/V and Y93/H in NS5A inhibitor-naive HCV genotype 1 patients who received asunaprevir plus daclatasvir combination treatment using ... Read more >>

PLoS One (PloS one)
[2020, 15(6):e0234811]

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Hypertrophic Cardiomyopathy - A Heterogeneous and Lifelong Disease in the Real World.

Hiroaki Kitaoka, Toru Kubo, Yoshinori L Doi,

Hypertrophic cardiomyopathy (HCM) is the most frequent hereditary cardiomyopathy, showing an autosomal-dominant f inheritance. A great deal of attention has been paid to genetics, left ventricular tract obstruction and the prediction and prevention of sudden cardiac death in HCM. Needless to say, these are very important, but we should recognize ... Read more >>

Circ J (Circulation journal : official journal of the Japanese Circulation Society)
[2020, 84(8):1218-1226]

Cited: 2 times

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Eosinophilic myocarditis associated with hypereosinophilic syndromes.

Junya Komatsu, Ryota Kida, Sho-Ichi Kubokawa, Yoshihiro Ohkawa, Hiroshi Sakaeda, Daisuke Kuzume, Masahiro Yamasaki, Kazuya Kawai, Naohisa Hamashige, Yoshinori Doi,

Geriatr Gerontol Int (Geriatrics & gerontology international)
[2020, 20(7):727-729]

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Dual-Chamber pacing for postoperative residual left ventricular gradient after aortic valve replacement and concomitant septal myectomy for severe aortic stenosis and subvalvular obstruction.

Hikaru Imafuku, Junya Komatsu, Ryuichiro Imai, Naoto Ohsawa, Yoko Nakaoka, Sho-Ichi Kubokawa, Kazuya Kawai, Naohisa Hamashige, Yoshinori Doi,

Background:Aortic stenosis is occasionally associated with subvalvular obstruction and remaining obstruction may at times be found after aortic valve replacement. Case report:A 69-year-old woman with a history of several episodes of unconsciousness was admitted because of exertional chest oppression. The echocardiography revealed severe aortic stenosis (flow velocity 6.2 m/sec, maximum ... Read more >>

J Cardiol Cases (Journal of cardiology cases)
[2020, 22(1):15-18]

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Death education for future physicians.

Taku Tajiri, Syun Matoba, Masanori Kuwabara, Yu-Ichi Baba, Toru Kubo, Naohito Yamasaki, Takashi Furuno, Hiroaki Kitaoka, Naohisa Hamashige, Yoshinori Doi,

Geriatr Gerontol Int (Geriatrics & gerontology international)
[2020, 20(1):5-6]

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Clinical Profile of Thromboembolic Events in Patients With Hypertrophic Cardiomyopathy in a Regional Japanese Cohort - Results From Kochi RYOMA Study.

Takayoshi Hirota, Toru Kubo, Yuichi Baba, Yuri Ochi, Asa Takahashi, Naohito Yamasaki, Naohisa Hamashige, Katsuhito Yamamoto, Fumiaki Kondo, Kanji Bando, Eisuke Yamada, Takashi Furuno, Toshikazu Yabe, Yoshinori L Doi, Hiroaki Kitaoka,

BACKGROUND:There is limited information about the clinical profiles of patients with hypertrophic cardiomyopathy (HCM) and thromboembolic events in a community-based Japanese patient cohort.Methods and Results:In 2004, we established a cardiomyopathy registration network in Kochi Prefecture that comprised 9 hospitals, and finally 293 patients with HCM were followed. The mean age at registration ... Read more >>

Circ J (Circulation journal : official journal of the Japanese Circulation Society)
[2019, 83(8):1747-1754]

Cited: 1 time

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A prospective multicenter observational study evaluating the risk of periendoscopic events in patients using anticoagulants: the Osaka GIANT Study.

Takuya Inoue, Hideki Iijima, Takuya Yamada, Yuji Okuyama, Kanae Takahashi, Tsutomu Nishida, Ryu Ishihara, Tomofumi Akasaka, Ichizo Kobayashi, Toshio Kuroshima, Yuichi Yasunaga, Katsumi Yamamoto, Masanori Nakahara, Yoshinori Doi, Sachiko Nakajima, Akira Mukai, Eiji Masuda, Shunsuke Yoshii, Yoshito Hayashi, Hitoshi Minamiguchi, Yasushi Sakata, Kouji Yamamoto, Masahiko Tsujii, Tetsuo Takehara,

Background and study aims  An increasing number of patients have been using anticoagulants including anti-vitamin K antagonists (VKAs) and direct oral anticoagulants (DOACs); however, in patients using anticoagulants, limited data are available with regard to the risks of gastrointestinal bleeding and thromboembolic events during the peri-endoscopic period. We aimed to ... Read more >>

Endosc Int Open (Endoscopy international open)
[2019, 7(2):E104-E114]

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Primary Cardiac Lymphoma: A Lesson Learned from an Unsuccessful Experience.

Izumi Ito, Yoko Nakaoka, Sho-Ichi Kubokawa, Hiroki Sugane, Takahiro Kusume, Hideyuki Matsuda, Ryu-Ichiro Imai, Koji Nishida, Toru Kubo, Naohito Yamasaki, Hiroaki Kitaoka, Kazuya Kawai, Naohisa Hamashige, Yoshinori Doi,

A 79-year-old man was admitted because of complete heart block. Echocardiograms showed an abnormal mass adjacent to the sinus of Valsalva. Subsequent surgical resection was not successful. Despite chemotherapy, the patient died from multiple organ failure. It is important to recognize that approximately 80% of cases of cardiac lymphoma are ... Read more >>

Intern Med (Internal medicine (Tokyo, Japan))
[2018, 57(24):3569-3574]

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Usefulness of Screening for Abdominal Aortic Aneurysm During Transthoracic Echocardiography in Women ≥50 Years of Age.

Yoshihisa Matsumura, Yuri Ochi, Michiko Wada, Daigo Hirakawa, Shigeo Yamanaka, Mikio Kamioka, Hiroaki Kitaoka, Kazumasa Orihashi, Yoko Nakaoka, Yoshinori Doi, Tetsuro Sugiura,

Usefulness of screening for abdominal aortic aneurysm (AAA) during transthoracic echocardiography (TTE) in women is uncertain. The aim of the present study was to clarify the clinical usefulness of screening for AAA during TTE and to identify important TTE indices associated with AAA in women in a routine clinical setting. ... Read more >>

Am J Cardiol (The American journal of cardiology)
[2018, 122(12):2147-2150]

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Patients' Characteristics and Clinical Course of Hypertrophic Cardiomyopathy in a Regional Japanese Cohort - Results From Kochi RYOMA Study.

Toru Kubo, Takayoshi Hirota, Yuichi Baba, Yuri Ochi, Asa Takahashi, Naohito Yamasaki, Naohisa Hamashige, Katsuhito Yamamoto, Fumiaki Kondo, Kanji Bando, Eisuke Yamada, Takashi Furuno, Toshikazu Yabe, Yoshinori L Doi, Hiroaki Kitaoka,

BACKGROUND:There have been few studies on the clinical course of hypertrophic cardiomyopathy (HCM) in a community-based patient cohort in Japan.Methods and Results:In 2004, we established a cardiomyopathy registration network in Kochi Prefecture (the Kochi RYOMA study) that consisted of 9 hospitals, and finally, 293 patients with HCM were followed. The ages at ... Read more >>

Circ J (Circulation journal : official journal of the Japanese Circulation Society)
[2018, 82(3):824-830]

Cited: 4 times

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Unilateral cardiogenic pulmonary edema.

Satoshi Inotani, Sho-Ichi Kubokawa, Yoko Nakaoka, Toshiaki Kotani, Hideyuki Matsuda, Satoshi Yamamoto, Shu-Ichi Seki, Kazuya Kawai, Naohisa Hamashige, Yoshinori Doi,

A 45-year-old man presented with fatigue for the previous two days. Because of severe hypoxemia and chest radiograph showing severe consolidation only in the right lung field, he was admitted to a near-by district hospital under the diagnosis of acute pneumonia. Since his respiratory condition rapidly deteriorated, he was transferred ... Read more >>

J Cardiol Cases (Journal of cardiology cases)
[2018, 17(3):85-88]

Cited: 2 times

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Multifactorial etiology of heart failure in older adults.

Yoko Hirakawa, Nana Takenaka, Miho Nishiyama, Kanji Bando, Hiroki Sugane, Koichi Asaba, Toru Kubo, Naohito Yamasaki, Hiroaki Kitaoka, Kazuya Kawai, Naohisa Hamashige, Yoshinori Doi,

Geriatr Gerontol Int (Geriatrics & gerontology international)
[2017, 17(9):1328-1329]

Cited: 0 times

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Subacute effusive-constrictive pericarditis: Echocardiography-guided diagnosis and management.

Naoto Ohsawa, Yoko Nakaoka, Sho-Ichi Kubokawa, Toru Kubo, Naohito Yamasaki, Hiroaki Kitaoka, Kazuya Kawai, Naohisa Hamashige, Yoshinori Doi,

A 49-year-old man presented with flu-like symptoms of two weeks. Electrocardiogram showed diffuse ST elevation. Blood samples revealed severe renal failure and moderate inflammatory results. Echocardiogram showed large pericardial effusion, dilated inferior vena cava, but no right ventricular collapse. The patient underwent hemodialysis, after which he developed clinical signs of ... Read more >>

J Cardiol Cases (Journal of cardiology cases)
[2017, 16(1):14-17]

Cited: 0 times

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