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Low blood sodium increases risk and severity of COVID-19: a systematic review, meta-analysis and retrospective cohort study

Yi Luo, Yirong Li, Jiapei Dai,

Background Novel coronavirus (SARS-CoV-2) infects human lung tissue cells through angiotensin-converting enzyme-2 (ACE2), and the body sodium is an important factor for regulating the expression of ACE2. Through a systematic review, meta-analysis and retrospective cohort study, we found that the low blood sodium population may significantly increase the risk and ... Read more >>

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Recurrent positive SARS-CoV-2 - immune certificate may not be valid.

Tao Liu, Sanyun Wu, Guang Zeng, Fuling Zhou, Yirong Li, Fangjian Guo, Xinghuan Wang,

Currently, coronavirus disease in 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)1 has become a global pandemic. The presence of SARS-CoV-2 in COVID-19 patients is usually confirmed using real-time reverse-transcriptase polymerase chain reaction (RT-PCR) method.2 This article is protected by copyright. All rights reserved. ... Read more >>

J. Med. Virol. (Journal of medical virology)
[2020, :]

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Clinical course and outcome of 107 patients infected with the novel coronavirus, SARS-CoV-2, discharged from two hospitals in Wuhan, China.

Dawei Wang, Yimei Yin, Chang Hu, Xing Liu, Xingguo Zhang, Shuliang Zhou, Mingzhi Jian, Haibo Xu, John Prowle, Bo Hu, Yirong Li, Zhiyong Peng,

BACKGROUND:In December 2019, coronavirus disease 2019 (COVID-19) outbreak was reported from Wuhan, China. Information on the clinical course and prognosis of COVID-19 was not thoroughly described. We described the clinical courses and prognosis in COVID-19 patients. METHODS:Retrospective case series of COVID-19 patients from Zhongnan Hospital of Wuhan University in Wuhan ... Read more >>

Crit Care (Critical Care)
[2020, 24(1):188]

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A rare case of NIPT discrepancy caused by the placental mosaicism of three different karyotypes, 47,XXX, 47,XX,+21, and 48,XXX,+21.

Jin Li, Mingshui Xie, Fang Wang, Jianhong Ma, Jiafu Li, Chen Chen, Zhimin Li, Juan Wang, Yuanzhen Zhang, Yirong Li,

BACKGROUND:Placental mosaicism is one of the major reasons for noninvasive prenatal testing (NIPT) discrepancy. Herein, we discovered a rare case of placenta with complex karyotypes that caused false-positive and false-negative results in noninvasive prenatal testing. METHODS:Next-generation sequencing (NGS) and Quantitative fluorescent polymerase chain reaction (QF-PCR) were performed on the cord ... Read more >>

Mol Genet Genomic Med (Molecular genetics & genomic medicine)
[2020, :e1279]

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Re: Profile of specific antibodies to SARS-CoV-2: The first report.

Zhikun Zeng, Liangjun Chen, Yunbao Pan, Qiaoling Deng, Guangming Ye, Yirong Li, Xinghuan Wang,

J. Infect. (The Journal of infection)
[2020, :]

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Serological immunochromatographic approach in diagnosis with SARS-CoV-2 infected COVID-19 patients.

Yunbao Pan, Xinran Li, Gui Yang, Junli Fan, Yueting Tang, Jin Zhao, Xinghua Long, Shuang Guo, Ziwu Zhao, Yinjuan Liu, Hanning Hu, Han Xue, Yirong Li,

An outbreak of new coronavirus SARS-CoV-2 was occurred in Wuhan, China and rapidly spread to other cities and nations. The standard diagnostic approach that widely adopted in the clinic is nucleic acid detection by real-time RT-PCR. However, the false-negative rate of the technique is unneglectable and serological methods are urgently ... Read more >>

J. Infect. (The Journal of infection)
[2020, :]

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Environmental contamination of SARS-CoV-2 in healthcare premises.

Guangming Ye, Hualiang Lin, Song Chen, Shichan Wang, Zhikun Zeng, Wei Wang, Shiyu Zhang, Terri Rebmann, Yirong Li, Zhenyu Pan, Zhonghua Yang, Ying Wang, Fubing Wang, Zhengmin Qian, Xinghuan Wang,

OBJECTIVES:A large number of healthcare workers (HCWs) were infected by SARS-CoV-2 during the ongoing outbreak of COVID-19 in Wuhan, China. Hospitals are significant epicenters for the human-to-human transmission of the SARS-CoV-2 for HCWs, patients, and visitors. No data has been reported on the details of hospital environmental contamination status in ... Read more >>

J. Infect. (The Journal of infection)
[2020, :]

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Asymptomatic SARS-CoV-2 Infection in Household Contacts of a Healthcare Provider, Wuhan, China.

Yi Luo, Edwin Trevathan, Zhengmin Qian, Yirong Li, Jin Li, Wei Xiao, Ning Tu, Zhikun Zeng, Pingzheng Mo, Yong Xiong, Guangming Ye,

We found that all 5 asymptomatic household contacts of a Wuhan, China, physician with coronavirus disease had severe acute respiratory syndrome coronavirus 2 detected by PCR. The index patient and 2 contacts also had abnormal chest computed tomography scans. Asymptomatic infected household contacts of healthcare workers with coronavirus disease might ... Read more >>

Emerging Infect. Dis. (Emerging infectious diseases)
[2020, 26(8):]

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Clinical characteristics of severe acute respiratory syndrome coronavirus 2 reactivation.

Guangming Ye, Zhenyu Pan, Yunbao Pan, Qiaoling Deng, Liangjun Chen, Jin Li, Yirong Li, Xinghuan Wang,

OBJECTIVES:Previous studies on the pneumonia outbreak caused by the 2019 novel coronavirus disease (COVID-19) were based on information from the general population. However, limited data was available for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reactivation. This study aimed to evaluate the clinical characteristics of the SARS-CoV-2 reactivation. METHODS:Clinical records, ... Read more >>

J. Infect. (The Journal of infection)
[2020, 80(5):e14-e17]

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Clinical course and outcome of 107 patients infected with the novel coronavirus, SARS-CoV-2, discharged from two hospitals in Wuhan, China.

Dawei Wang, Yimei Yin, Chang Hu, Xing Liu, Xingguo Zhang, Shuliang Zhou, Mingzhi Jian, Haibo Xu, John Prowle, Bo Hu, Yirong Li, Zhi-Yong Peng,

Abstract Background In December 2019, Coronavirus Disease 2019 (COVID-19) outbreak was reported from Wuhan, China. Information on the clinical course and prognosis of COVID-19 was not thoroughly described. We described the clinical courses and prognosis in COVID-19 patients. Methods Retrospective case series of COVID-19 patients from Zhongnan Hospital of Wuhan ... Read more >>

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Experience of different upper respiratory tract sampling strategies for detection of COVID-19.

Guangming Ye, Yirong Li, Mengxin Lu, Song Chen, Yongwen Luo, Shichan Wang, Yejingpeng Wang, Xinghuan Wang,

J. Hosp. Infect. (The Journal of hospital infection)
[2020, :]

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Serological immunochromatographic approach in diagnosis with SARS-CoV-2 infected COVID-19 patients

Yunbao Pan, Xinran Li, Gui Yang, Junli Fan, Yueting Tang, Jin Zhao, Xinghua Long, Shuang Guo, Ziwu Zhao, Yinjuan Liu, Hanning Hu, Han Xue, Yirong Li,

An outbreak of new coronavirus SARS-CoV-2 was occurred in Wuhan, China and rapidly spread to other cities and nations. The standard diagnostic approach that widely adopted in the clinic is nuclear acid detection by real-time RT-PCR. However, the false-negative rate of the technique is unneglectable and serological methods are urgently ... Read more >>

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Prognostic Value of Clinical Biochemistry-Based Indexes in Nasopharyngeal Carcinoma.

Xiaojiao Zeng, Guohong Liu, Yunbao Pan, Yirong Li,

Inflammation and nutritional status have significant effects on the prognosis of cancer patients. This study investigated the predictive value of clinical biochemistry-based indexes in nasopharyngeal carcinoma (NPC). This retrospective study included 559 NPC patients and 500 patients with chronic rhinitis. Continuous variables were measured by t-test. The area under curves ... Read more >>

Front Oncol (Frontiers in Oncology)
[2020, 10:146]

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Environmental contamination of the SARS-CoV-2 in healthcare premises: An urgent call for protection for healthcare workers

Guangming Ye, Hualiang Lin, Liangjun Chen, Shichan Wang, Zhikun Zeng, Wei Wang, Shiyu Zhang, Terri Rebmann, Yirong Li, Zhenyu Pan, Zhonghua Yang, Ying Wang, Fubing Wang, Zhengmin Qian, Xinghuan Wang,

Importance A large number of healthcare workers (HCWs) were infected by SARS-CoV-2 during the ongoing outbreak of COVID-19 in Wuhan, China. Hospitals are significant epicenters for the human-to-human transmission of the SARS-CoV-2 for HCWs, patients, and visitors. No data has been reported on the details of hospital environmental contamination status ... Read more >>

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Can routine laboratory tests discriminate 2019 novel coronavirus infected pneumonia from other community-acquired pneumonia?

Yunbao Pan, Guangming Ye, Xiantao Zeng, Guohong Liu, Xiaojiao Zeng, Xianghu Jiang, Jin Zhao, Liangjun Chen, Shuang Guo, Qiaoling Deng, Xiaoyue Hong, Ying Yang, Yirong Li, Xinghuan Wang,

Background. The clinical presentation of 2019 Novel Coronavirus (2019-nCov) infected pneumonia (NCIP) resembles that of other etiologies of community-acquired pneumonia (CAP). We aimed to identify clinical laboratory features to distinguish NCIP from CAP. Methods. We compared the ability of the hematological and biochemical features of 84 patients with NCIP at ... Read more >>

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Positive RT-PCR Test Results in Patients Recovered From COVID-19.

Lan Lan, Dan Xu, Guangming Ye, Chen Xia, Shaokang Wang, Yirong Li, Haibo Xu,

JAMA (JAMA)
[2020, :]

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Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.

Dawei Wang, Bo Hu, Chang Hu, Fangfang Zhu, Xing Liu, Jing Zhang, Binbin Wang, Hui Xiang, Zhenshun Cheng, Yong Xiong, Yan Zhao, Yirong Li, Xinghuan Wang, Zhiyong Peng,

Importance:In December 2019, novel coronavirus (2019-nCoV)-infected pneumonia (NCIP) occurred in Wuhan, China. The number of cases has increased rapidly but information on the clinical characteristics of affected patients is limited. Objective:To describe the epidemiological and clinical characteristics of NCIP. Design, Setting, and Participants:Retrospective, single-center case series of the 138 consecutive ... Read more >>

JAMA (JAMA)
[2020, :]

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RNA based mNGS approach identifies a novel human coronavirus from two individual pneumonia cases in 2019 Wuhan outbreak.

Liangjun Chen, Weiyong Liu, Qi Zhang, Ke Xu, Guangming Ye, Weichen Wu, Ziyong Sun, Fang Liu, Kailang Wu, Bo Zhong, Yi Mei, Wenxia Zhang, Yu Chen, Yirong Li, Mang Shi, Ke Lan, Yingle Liu,

From December 2019, an outbreak of unusual pneumonia was reported in Wuhan with many cases linked to Huanan Seafood Market that sells seafood as well as live exotic animals. We investigated two patients who developed acute respiratory syndromes after independent contact history with this market. The two patients shared common ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2020, 9(1):313-319]

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A novel "on-off-on" fluorescence assay for the discriminative detection of Cu(ii) and l-cysteine based on red-emissive Si-CDs and cellular imaging applications.

Minghui Zan, Cong Li, Daoming Zhu, Lang Rao, Qian-Fang Meng, Bei Chen, Wei Xie, Xingwang Qie, Li Li, Xiaojiao Zeng, Yirong Li, Wen-Fei Dong, Wei Liu,

Copper ions (Cu2+) and l-cysteine (l-Cys) in the human body always play critical roles in various physiological processes, while abnormal Cu2+ and l-Cys concentrations in the biological system lead to many diseases. In this manuscript, Si-doped carbon dots (Si-CDs) with near-infrared fluorescence were designed for the detection of Cu2+ and ... Read more >>

J Mater Chem B (Journal of materials chemistry. B)
[2020, 8(5):919-927]

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Characteristics of Bacterial Community and Function in Paddy Soil Profile around Antimony Mine and Its Response to Antimony and Arsenic Contamination.

Bocong Huang, Jian Long, Hongkai Liao, Lingfei Liu, Juan Li, Jumei Zhang, Yirong Li, Xian Wang, Rui Yang,

Research of bacterial communities and metabolism potential of paddy soils contaminated by antimony (Sb) and arsenic (As) are vital to acquire understanding for their bioremediation. Here, the relative abundance of Sb and As metabolism genes, the diversity and composition of the bacterial community, and the influences of geochemical properties and ... Read more >>

Int J Environ Res Public Health (International journal of environmental research and public health)
[2019, 16(24):]

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Molecular characteristics and virulence gene profiles of Staphylococcus aureus isolates in Hainan, China.

Xuehan Li, Tao Huang, Kai Xu, Chenglin Li, Yirong Li,

BACKGROUND:There have been no reports regarding the molecular characteristics, virulence features, and antibiotic resistance profiles of Staphylococcus aureus (S. aureus) from Hainan, the southernmost province of China. METHODS:Two hundred twenty-seven S. aureus isolates, consisting of 76 methicillin-resistant S. aureus (MRSA) and 151 methicillin-susceptible S. aureus (MSSA), were collected in 2013-2014 ... Read more >>

BMC Infect. Dis. (BMC infectious diseases)
[2019, 19(1):873]

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Pandoraea sputorum Bacteremia In A Patient Who Had Undergone Allogeneic Liver Transplantation Plus Immunosuppressive Therapy: A Case Report.

Xiao Xiao, Hongpan Tian, Xiaohuan Cheng, Guoming Li, Junying Zhou, Zhiyong Peng, Yirong Li,

Pandoraea sputorum (P. sputorum), an emerging pathogen, is able to trigger a pronounced pro-inflammatory response that results in lung dysfunction in cystic fibrosis (CF) patients. All previous P. sputorum isolates have been obtained from the respiratory samples of CF patients, with no reported cases of P. sputorum bacteremia. For the ... Read more >>

Infect Drug Resist (Infection and drug resistance)
[2019, 12:3359-3364]

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Molecular characteristics and virulence gene profiles of Staphylococcus aureus isolates in Hainan, China

Xuehan Li, Tao Huang, Kai Xu, Chenglin Li, Yirong Li,

Abstract Background: There have been no reports regarding the molecular characteristics, virulence features, and antibiotic resistance profiles of Staphylococcus aureus ( S. aureus ) from Hainan, the southernmost province of China. Methods: 227 S. aureus isolates, consisting of 76 methicillin-resistant S. aureus (MRSA) and 151 methicillin-susceptible S. aureus (MSSA), were ... Read more >>

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Fumarate hydratase FH c.1431_1433dupAAA (p.Lys477dup) variant is not associated with cancer including renal cell carcinoma.

Liying Zhang, Michael F Walsh, Sowmya Jairam, Diana Mandelker, Yi Zhong, Yelena Kemel, Ying-Bei Chen, David Musheyev, Ahmet Zehir, Gowtham Jayakumaran, Edyta Brzostowski, Ozge Birsoy, Ciyu Yang, Yirong Li, Joshua Somar, Deborah DeLair, Nisha Pradhan, Michael F Berger, Karen Cadoo, Maria I Carlo, Mark E Robson, Zsofia K Stadler, Christine A Iacobuzio-Donahue, Vijai Joseph, Kenneth Offit,

Fumarate hydratase (FH) mutations underpin the autosomal recessive syndrome. FH deficiency and the autosomal dominant syndrome hereditary leiomyomatosis and renal cell carcinoma (HLRCC). The FH c.1431_1433dupAAA (p.Lys477dup) genomic alteration has been conclusively shown to contribute to FH deficiency when occurring with another FH germline alteration. However, a sufficiently large dataset ... Read more >>

Hum. Mutat. (Human mutation)
[2020, 41(1):103-109]

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Analysis of lncRNA-Mediated ceRNA Crosstalk and Identification of Prognostic Signature in Head and Neck Squamous Cell Carcinoma.

Yunbao Pan, Guohong Liu, Dujuan Wang, Yirong Li,

Long non-coding RNA (lncRNA) can act as ceRNA to regulate the expression of target genes by sponging miRNAs, and therefore plays an essential role in tumor initiation and progression. However, functional roles and regulatory mechanisms of lncRNAs as ceRNAs in head and neck squamous cell carcinoma (HNSCC) remain to be ... Read more >>

Front Pharmacol (Frontiers in pharmacology)
[2019, 10:150]

Cited: 3 times

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