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How does overall hospital satisfaction relate to patient experience with nursing care? a cross-sectional study in China.

Xiao Chen, Yuxia Zhang, Wei Qin, Zhenghong Yu, JingXian Yu, Ying Lin, XiaoRong Li, Zheng Zheng, Ying Wang,

<h4>Objective</h4>To determine how patient experience with nursing care influence patient satisfaction with overall hospital services.<h4>Design</h4>This was a cross-sectional study.<h4>Setting</h4>Inpatients were consecutively recruited at the national hospital (with 2000 beds) in Shanghai, China.<h4>Participants</h4>The inclusion criteria were as follows: (1) hospitalised for 2 days or more; (2) able to read and understand Chinese; ... Read more >>

BMJ Open (BMJ open)
[2022, 12(1):e053899]

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Functional connectivity dynamics as a function of the fluctuation of tension during film watching.

Yadi Sun, Junji Ma, Miner Huang, Yangyang Yi, Yiheng Wang, Yue Gu, Ying Lin, Liman Man Wai Li, Zhengjia Dai,

To advance the understanding of the dynamic relationship between brain activities and emotional experiences, we examined the neural patterns of tension, a unique emotion that highly depends on how an event unfolds. Specifically, the present study explored the temporal relationship between functional connectivity patterns within and between different brain functional ... Read more >>

Brain Imaging Behav (Brain imaging and behavior)
[2022, :]

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Soluble VE-cadherin: not just a marker of endothelial permeability.

Shi Qi Li, Ying Ni Lin, Qing Yun Li,

Eur Respir J (The European respiratory journal)
[2021, 58(6):]

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Toward efficient multiple-site incorporation of unnatural amino acids using cell-free translation system.

Jiaqi Hou, Xinjie Chen, Nan Jiang, Yanan Wang, Yi Cui, Lianju Ma, Ying Lin, Yuan Lu,

Amber suppression has been widely used to incorporate unnatural amino acids (UNAAs) with unique structures or functional side-chain groups into specific sites of the target protein, which expands the scope of protein-coding chemistry. However, this traditional strategy does not allow multiple-site incorporation of different UNAAs into a single protein, which ... Read more >>

Synth Syst Biotechnol (Synthetic and systems biotechnology)
[2022, 7(1):522-532]

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Study on the effect of outpatient nursing intervention on medical compliance of diabetes mellitus during pregnancy.

Yan Li, Lan Wu, Ying Lin,

Minerva Med (Minerva medica)
[2021, :]

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A Hybrid Communication Pattern in Brain Structural Network Revealed by Evolutionary Computation

Quanmin Liang, Junji Ma, Xitian Chen, Zhengjia Dai, Ying Lin,

<h4>Summary</h4> The human brain functional connectivity network (FCN) is constrained and shaped by the information communication processes in the structural connectivity network (SCN). The underlying communication model thus becomes a critical issue for understanding structure-function coupling in the human brain. A number of communication models featuring different point-to-point routing strategies ... Read more >>

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Fluorescent Indicators for Live-Cell and in Vitro Detection of Inorganic Cadmium Dynamics

Shulin Hu, Jun Yang, Anqi Liao, Ying Lin, Shuli Liang,

Cadmium contamination is a severe threat to the environment and food safety. Thus, there is an urgent need to develop highly sensitive and selective cadmium detection tools. The engineered fluorescent indicator is a powerful tool for the rapid detection of inorganic cadmium in the environment. In this study, the development ... Read more >>

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Effect of Mass Azithromycin Distributions on Childhood Growth in Niger: A Cluster-Randomized Trial.

Ahmed M Arzika, Ramatou Maliki, Maria M Ali, Mankara K Alio, Amza Abdou, Sun Y Cotter, Nicole E Varnado, Elodie Lebas, Catherine Cook, Catherine E Oldenburg, Kieran S O'Brien, E Kelly Callahan, Robin L Bailey, Sheila K West, Travis C Porco, Thomas M Lietman, Jeremy D Keenan, ,

<h4>Importance</h4>Mass azithromycin distributions may decrease childhood mortality, although the causal pathway is unclear. The potential for antibiotics to function as growth promoters may explain some of the mortality benefit.<h4>Objective</h4>To investigate whether biannual mass azithromycin distributions are associated with increased childhood growth.<h4>Design, setting, and participants</h4>This cluster-randomized trial was performed from December ... Read more >>

JAMA Netw Open (JAMA network open)
[2021, 4(12):e2139351]

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Construction of nursing-sensitive quality indicators for cardiac catheterisation: A Delphi study and an analytic hierarchy process.

Zhiyun Shen, Wei Qin, Li Zhu, Ying Lin, Huaxing Ling, Yuxia Zhang,

<h4>Background</h4>Nursing care can profoundly reduce the risk of emergencies related to cardiac catheterisation. Therefore, identifying nursing-sensitive quality indicators (NSQIs) to evaluate nursing quality is critical for optimal cardiac catheterisation. However, studies on NSQIs for cardiac catheterisation are scarce.<h4>Objectives</h4>This study was conducted to develop a set of NSQIs for cardiac catheterisation.<h4>Methods</h4>Literature ... Read more >>

J Clin Nurs (Journal of clinical nursing)
[2021, :]

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Trastuzumab Plus Endocrine Therapy or Chemotherapy as First-line Treatment for Patients with Hormone Receptor-Positive and HER2-Positive Metastatic Breast Cancer (SYSUCC-002).

Xin Hua, Xi-Wen Bi, Jian-Li Zhao, Yan-Xia Shi, Ying Lin, Zhi-Yong Wu, Yuan-Qi Zhang, Le-Hong Zhang, An-Qing Zhang, Heng Huang, Xin-Mei Liu, Fei Xu, Ying Guo, Wen Xia, Ruo-Xi Hong, Kui-Kui Jiang, Cong Xue, Xin An, Yong-Yi Zhong, Shu-Sen Wang, Jia-Jia Huang, Zhong-Yu Yuan, ,

<h4>Purpose</h4>There is no research evidence demonstrate which is the better partner strategy, endocrine therapy or chemotherapy, to combine with anti-HER2 therapy as the first-line management of hormone receptor (HR)-positive (HR<sup>+</sup>) and HER2-positive (HER2<sup>+</sup>) metastatic breast cancer (MBC). We wished to ascertain if trastuzumab plus endocrine therapy is noninferior to trastuzumab ... Read more >>

Clin Cancer Res (Clinical cancer research : an official journal of the American Association for Cancer Research)
[2021, :]

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Clinical presentation of gastric Burkitt lymphoma presenting with paraplegia and acute pancreatitis: A case report.

Ying Lin, Yu-Hang Pan, Ming-Kai Li, Xiao-Dan Zong, Xue-Mei Pan, Shu-Yan Tan, Yun-Wei Guo,

<h4>Background</h4>The incidence of gastric Burkitt lymphoma (BL), presenting as paraplegia and acute pancreatitis, is extremely low. BL is a great masquerader that presents in varied forms and in atypical locations, and it is prone to misdiagnosis and missed diagnosis. The prognosis of BL remains poor because of the difficulty in ... Read more >>

World J Gastroenterol (World journal of gastroenterology)
[2021, 27(45):7844-7854]

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Green Process: Improved Semi-Continuous Fermentation of Pichia pastoris Based on the Principle of Vitality Cell Separation.

Denggang Wang, Wenjie Li, Xinying Zhang, Shuli Liang, Ying Lin,

The large-scale fermentation of Pichia pastoris for recombinant protein production would be time consuming and produce a large amount of waste yeast. Here we introduce a novel semi-continuous fermentation process for P. pastoris GS115 that can separate vitality cells from broth and recycle the cells to produce high-secretory recombinant pectate ... Read more >>

Front Bioeng Biotechnol (Frontiers in bioengineering and biotechnology)
[2021, 9:777774]

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CIC missense variants contribute to susceptibility for spina bifida

Xiao Han, Xuanye Cao, Vanessa Aguiar-Pulido, Wei Yang, Menuka Karki, Paula Andrea Pimienta Ramirez, Robert Cabrera, Ying Lin, Bogdan Wlodarczyk, Gary Shaw, Margaret Ross, Cuilian Zhang, Richard Finnell, Yunping Lei,

Neural Tube Defects (NTDs) are congenital malformations resulting from abnormal embryonic development of the brain, spine, or spinal column. The genetic etiology of human NTDs remains poorly understood despite intensive investigation. CIC, homolog of the Capicua transcription repressor, has been reported to interact with ataxin-1 (ATXN1) and participate in the ... Read more >>

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A novel peptide inhibitor of Dll4-Notch1 signalling and its pro-angiogenic functions.

Guofu Zhu, Ying Lin, Tandi Ge, Shekhar Singh, Hao Liu, Linlin Fan, Shumin Wang, Jordan Rhen, Dongyang Jiang, Yuyan Lyu, Yiheng Yin, Xiankai Li, Danielle S W Benoit, Weiming Li, Yawei Xu, Jinjiang Pang,

<h4>Background and purpose</h4>The Dll4-Notch1 signalling pathway plays an important role in sprouting angiogenesis, vascular remodelling and arterial or venous specificity. Genetic or pharmacological inhibition of Dll4-Notch1 signalling leads to excessive sprouting angiogenesis. However, transcriptional inhibitors of Dll4-Notch1 signalling have not been described.<h4>Experimental approach</h4>We designed a new peptide targeting Notch signalling, ... Read more >>

Br J Pharmacol (British journal of pharmacology)
[2021, :]

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Epidemiology of Acute Myocarditis/Pericarditis in Hong Kong Adolescents Following Comirnaty Vaccination.

Gilbert T Chua, Mike Yat Wah Kwan, Celine S L Chui, Robert David Smith, Edmund Chi-Lok Cheung, Tian Tian, Miriam T Y Leung, Sabrina Siu Ling Tsao, Elaine Kan, Wing Kei Carol Ng, Victor Chi Man Chan, Shuk Mui Tai, Tak Ching Yu, Kwok Piu Lee, Joshua Sung Chih Wong, Ying Kit Lin, Chi Chiu Shek, Agnes Sze Yin Leung, Chit Kwong Chow, Ka Wah Li, Johnny Ma, Wai Yuk Fung, Daniel Lee, Ming Yen Ng, Wilfred Hing Sang Wong, Hing Wai Tsang, Janette Kwok, Daniel Leung, Kin Lai Chung, Chun Bong Chow, Godfrey Chi Fung Chan, Wing Hang Leung, Kelvin Kai Wang To, Kwok Yung Yuen, Yu Lung Lau, Ian Chi Kei Wong, Patrick Ip,

<h4>Background</h4>Age-specific incidence of acute myocarditis/pericarditis in adolescents following Comirnaty vaccination in Asia is lacking. This study aimed to study the clinical characteristics and incidence of acute myocarditis/pericarditis among Hong Kong adolescents following Comirnaty vaccination.<h4>Methods</h4>This is a population cohort study in Hong Kong that monitored adverse events following immunization through a ... Read more >>

Clin Infect Dis (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2021, :]

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The exposure levels of phthalates in pregnant women and impact factors of fetal malformation.

Ling Wang, Wei Duan, Yun Zhao, Guoqiang Sun, Ying Lin, Ying Gao,

<h4>Methods</h4>Urine samples were collected from 157 women with fetal malformations (case group) and 147 women with normal fetuses (control group). High-performance liquid chromatography-mass spectrometry (HPLC-MS) was used to detect the content of eight metabolites of phthalate compounds in urine, including monoethyl phthalate (MEP), mononbutyl phthalate (MBP), monoisobutyl phthalate (MiBP), mono-(2-ethylhexyl) ... Read more >>

Hum Exp Toxicol (Human & experimental toxicology)
[2021, 40(12_suppl):S622-S631]

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Gene expression associated with individual variability in intrinsic functional connectivity.

Liangfang Li, Yongbin Wei, Jinbo Zhang, Junji Ma, Yangyang Yi, Yue Gu, Liman Man Wai Li, Ying Lin, Zhengjia Dai,

It has been revealed that intersubject variability (ISV) in intrinsic functional connectivity (FC) is associated with a wide variety of cognitive and behavioral performances. However, the underlying organizational principle of ISV in FC and its related gene transcriptional profiles remain unclear. Using resting-state fMRI data from the Human Connectome Project ... Read more >>

Neuroimage (NeuroImage)
[2021, 245:118743]

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Maximizing Lifetime of Range-Adjustable Wireless Sensor Networks: A Neighborhood-Based Estimation of Distribution Algorithm.

Zong-Gan Chen, Ying Lin, Yue-Jiao Gong, Zhi-Hui Zhan, Jun Zhang,

Sensor activity scheduling is critical for prolonging the lifetime of wireless sensor networks (WSNs). However, most existing methods assume sensors to have one fixed sensing range. Prevalence of sensors with adjustable sensing ranges posts two new challenges to the topic: 1) expanded search space, due to the rise in the ... Read more >>

IEEE Trans Cybern (IEEE transactions on cybernetics)
[2021, 51(11):5433-5444]

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1-42].">[Abdominal acupoint thread embedding therapy based on "brain-intestinal connection" for mild-to-moderate Alzheimer's disease and its effects on serum levels of APP and Aβ1-42].

Shu-Quan Yang, De-Hui Fan, Zhi-Xian Yuan, Mei-Yi Su, Zhen-Ning Zhang, Ying Lin, Hu-Guang Lin,

<h4>Objective</h4>To compare the clinical efficacy of abdominal acupoint thread embedding therapy based on "brain-intestinal connection" combined with donepezil hydrochloride tablets and oral donepezil hydrochloride tablets alone for mild-to-moderate Alzheimer's disease (AD) and observe its effects on amyloid precursor protein (APP) and β-amyloid protein<sub>1-42</sub> (Aβ<sub>1-42</sub>).<h4>Methods</h4>Sixty patients with AD were randomly divided ... 1-42].">Read more >>

Zhongguo Zhen Jiu (Zhongguo zhen jiu = Chinese acupuncture & moxibustion)
[2021, 41(11):1231-1235]

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Muscular pathological features in patients with myasthenia gravis.

Lingya Qiao, Yutong Zhang, Rui Ban, Ying Lin, Chuanqiang Pu, Qiang Shi,

<h4>Objective</h4>To analyze muscle histopathology of myasthenia gravis (MG) patients and further explore the underlying mechanism comparing with previous literature.<h4>Materials and methods</h4>We analyzed the clinicopathological features of 8 MG patients who had muscle biopsy examinations.<h4>Results</h4>Eight patients with a diagnosis of MG were retrospectively recruited from the Chinese PLA General Hospital. One ... Read more >>

Clin Neuropathol (Clinical neuropathology)
[2021, 40(6):319-327]

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The overlapping modular organization of human brain functional networks across the adult lifespan

Yue Gu, Liangfang Li, Yining Zhang, Junji Ma, Chenfan Yang, Yu Xiao, Ni Shu, Ying Lin, Zhengjia Dai, ,

Previous lifespan studies have demonstrated that the brain functional modular organization would change along with the adult lifespan. Yet, they assumed mutual exclusion among functional modules, ignoring convergent evidence for the existence of modular overlap. To reveal how age affects the overlapping functional modular organization, this study applied a detection ... Read more >>

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Characterization of prolactin (PRL) and PRL receptor (PRLR) in Chinese soft-shelled turtle: Molecular identification, ligand-receptor interaction and tissue distribution.

Ming Yang, Ming Yang, Ying Lin, Fengyan Meng, Xiaogang Du, Xianyin Zeng, Guixian Bu,

Prolactin (PRL) plays crucial roles in many physiological and pathological processes through activating its specific membrane-anchored receptor (PRLR). Although this ligand-receptor pair has been extensively studied in mammals, birds and fishes, researches examining their significance is rather scarce in reptiles. Additionally, the interaction mechanism of PRL-PRLR has abortively understood across ... Read more >>

Gen Comp Endocrinol (General and comparative endocrinology)
[2022, 316:113941]

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Dissecting the heterogeneity and tumorigenesis of BRCA1 deficient mammary tumors via single cell RNA sequencing.

Heng Sun, Jianming Zeng, Zhengqiang Miao, Kuan Cheok Lei, Chen Huang, Lingling Hu, Sek Man Su, Un In Chan, Kai Miao, Xu Zhang, Aiping Zhang, Sen Guo, Si Chen, Ya Meng, Min Deng, Wenhui Hao, Haipeng Lei, Ying Lin, Zhonglin Yang, Dongjiang Tang, Koon Ho Wong, Xiaohua Douglas Zhang, Xiaoling Xu, Chu-Xia Deng,

<b>Background:</b> BRCA1 plays critical roles in mammary gland development and mammary tumorigenesis. And loss of BRCA1 induces mammary tumors in a stochastic manner. These tumors present great heterogeneity at both intertumor and intratumor levels. <b>Methods:</b> To comprehensively elucidate the heterogeneity of BRCA1 deficient mammary tumors and the underlying mechanisms for ... Read more >>

Theranostics (Theranostics)
[2021, 11(20):9967-9987]

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CircCD44 plays oncogenic roles in triple-negative breast cancer by modulating the miR-502-5p/KRAS and IGF2BP2/Myc axes.

Jie Li, Xinya Gao, Zhanqiang Zhang, Yuanhui Lai, Xunxun Lin, Bo Lin, Maoguang Ma, Xiaoli Liang, Xixi Li, Weiming Lv, Ying Lin, Nu Zhang,

<h4>Background</h4>Emerging studies have revealed the potent functions of circRNAs in breast cancer tumorigenesis. However, the biogenesis, biofunction and mechanism of circRNAs in triple-negative breast cancer (TNBC) are largely unknown.<h4>Methods</h4>High-throughput RNA sequencing was applied to identify dysregulated circRNAs in TNBCs and paired normal tissues. RNA pulldown and luciferase assays were performed ... Read more >>

Mol Cancer (Molecular cancer)
[2021, 20(1):138]

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Epidemiology of Underweight among Infants in Rural Burkina Faso.

Ali Sié, Mamadou Ouattara, Mamadou Bountogo, Clarisse Dah, Guillaume Compaore, Elodie Lebas, Jessica M Brogdon, Ying Lin, William W Godwin, Kieran S O'Brien, Benjamin F Arnold, Thomas M Lietman, Catherine E Oldenburg, ,

Infant undernutrition is thought to contribute to growth failure and mortality. We evaluated the patterns in underweight in a population-based sample of children aged 1-11 months in rural northwestern Burkina Faso. Data were collected during the baseline assessment of a community-randomized trial evaluating mass azithromycin distribution in Nouna District, Burkina ... Read more >>

Am J Trop Med Hyg (The American journal of tropical medicine and hygiene)
[2021, 106(1):361-368]

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