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Author Ying Jing

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Urinary Molecular Pathology for Patients with Newly Diagnosed Urothelial Bladder Cancer.

Ruiyun Zhang, Jingyu Zang, Feng Xie, Yue Zhang, Yiqiu Wang, Ying Jing, Yi Zhang, Zhaoxiong Chen, Akezhouli Shahatiaili, Mei-Chun Cai, Zhixin Zhao, Pan Du, Shidong Jia, Guanglei Zhuang, Haige Chen,

<h4>Purpose</h4>Next-generation sequencing (NGS)-based profiling of both urinary tumor DNA (utDNA) and circulating tumor DNA (ctDNA) shows promise for noninvasive detection and surveillance of urothelial bladder cancer (UBC). However, the analytic performance of these assays remains undefined in the real-world setting. Here, we sought to evaluate the concordance between tumor DNA ... Read more >>

J Urol (The Journal of urology)
[2021, :101097JU0000000000001878]

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Three bacterium-plasmid golden combinations facilitate the spread of ST11/CG258 carbapenemase-producing Klebsiella pneumoniae in China

Cuidan Li, Xiaoyuan Jiang, Tingting Yang, Yingjiao Ju, Zhe Yin, Liya Yue, Guanan Ma, Xuebing Wang, Ying Jing, Xinhua Luo, Shuangshuang Li, Xue Yang, Fei Chen, Dongsheng Zhou,

Carbapenemase-producing Klebsiella pneumoniae (cpKP) poses serious threats to public health. Previous studies showed that only ST11/CG258-cpKP successfully disseminated in China, however, the underlying genetic bases are still unknown. We conducted a comprehensive genomic-epidemiology analysis on 420 cpKP isolates from 70 hospitals in 24 Chinese provinces during 2009-2017 based on short-/long-reads ... Read more >>

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Osteocalcin and Abdominal Aortic Calcification in Hemodialysis Patients: An Observational Cross-Sectional Study.

Fengyu Jia, Suxia Wang, Ying Jing, Hanhui Zhao, Peng Rong, Hongbin Zhang, Wenting Lu, Yan Xue, Gang Sun,

<h4>Objectives</h4>To investigate the serum level of osteocalcin (OC), also known as bone Gla protein, in maintenance hemodialysis (MHD) patients and its correlation with abdominal aortic calcification (AAC).<h4>Methods</h4>From July 2017 to February 2020, we enrolled 108 adult MHD patients. Routine fasting blood laboratory tests were performed before the start of the ... Read more >>

Front Endocrinol (Lausanne) (Frontiers in endocrinology)
[2021, 12:620350]

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Novel Chromosome-Borne Accessory Genetic Elements Carrying Multiple Antibiotic Resistance Genes in Pseudomonas aeruginosa.

Ting Yu, Huiying Yang, Jun Li, Fangzhou Chen, Lingfei Hu, Ying Jing, Xinhua Luo, Zhe Yin, Mingxiang Zou, Dongsheng Zhou,

<i>Pseudomonas aeruginosa</i> is noted for its intrinsic antibiotic resistance and capacity of acquiring additional resistance genes. In this study, the genomes of nine clinical <i>P. aeruginosa</i> isolates were fully sequenced. An extensive genetic comparison was applied to 18 <i>P. aeruginosa</i> accessory genetic elements (AGEs; 13 of them were sequenced in this ... Read more >>

Front Cell Infect Microbiol (Frontiers in cellular and infection microbiology)
[2021, 11:638087]

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Association Between Sex and Immune-Related Adverse Events During Immune Checkpoint Inhibitor Therapy.

Ying Jing, Yongchang Zhang, Jing Wang, Kunyan Li, Xue Chen, Jianfu Heng, Qian Gao, Youqiong Ye, Zhao Zhang, Yaoming Liu, Yanyan Lou, Steven H Lin, Lixia Diao, Hong Liu, Xiang Chen, Gordon B Mills, Leng Han,

<h4>Background</h4>Accumulated evidence supports the existence of sex-associated differences in immune systems. Understanding the role of sex in immune-related adverse events (irAEs) is important for management of irAE in patients receiving immunotherapy.<h4>Methods</h4>We performed meta-analysis on published clinical study data and multivariable logistic regression on pharmacovigilance data and applied a propensity algorithm ... Read more >>

J Natl Cancer Inst (Journal of the National Cancer Institute)
[2021, :]

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Adverse events associated with potential drugs for COVID-19: a case study from real-world data.

Ying Jing, Lixia Diao, Leng Han,

The coronavirus disease 2019 (COVID-19) has resulted as a global pandemic. The World Health Organization announced the most promising drugs in SOLIDARITY for the global trial, and several other drugs are under investigation through ongoing clinical trials to prove the effectiveness and safety of potential therapeutics. Here, we depicted the ... Read more >>

Brief Bioinform (Briefings in bioinformatics)
[2021, 22(2):1232-1238]

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A ras-related small GTP-binding protein, RabE1c, regulates stomatal movements and drought stress responses by mediating the interaction with ABA receptors.

Donghua Chen, Lilong He, Minyan Lin, Ying Jing, Chaochao Liang, Huiping Liu, Jianwei Gao, Wei Zhang, Mei Wang,

Drought represents a leading constraint over crop productivity worldwide. The plant response to this stress is centered on the behavior of the cell membrane, where the transduction of abscisic acid (ABA) signaling occurs. Here, the Ras-related small GTP-binding protein RabE1c has been shown able to bind to an ABA receptor ... Read more >>

Plant Sci (Plant science : an international journal of experimental plant biology)
[2021, 306:110858]

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Retraction notice to "Effects of total parathyroidectomy treatment on parathyroid hormone levels, recurrent laryngeal nerve function, and the rate of infection complications of secondary hyperparathyroidism patients under image information health monitoring by magnetic resonance imaging" [Neurosci. Lett. 735 (September) (2020) 135195].

Fengyu Jia, Yan Xue, Kai Liu, Suxia Wang, Ying Jing, Dandan Li, Hanhui Zhao, Bo Li, Wenyuan Liu, Gang Sun,

Neurosci Lett (Neuroscience letters)
[2021, 747:135703]

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[Clinical effects between cannulated screw and bone plate internal fixation for humeral tuberosity fracture:a Meta analysis].

Xiang Wu, Fei Li, Jing Ying, Bin Chen, Yu-Xuan Su, Hai-Yu Sun,

<h4>Objective</h4>To compare clinical effect of cannulated screw and bone plate for the treatment of humeral fracture of greater tuberosity.<h4>Methods</h4>From January 2010 to January 2020, clinical trial literatures on the treatment of humeral tuberosity fractures with cannulated screw and bone plate were searched by PubMed, EMbase, Cochrane Library, Wanfang, CNKI, CBM ... Read more >>

Zhongguo Gu Shang (Zhongguo gu shang = China journal of orthopaedics and traumatology)
[2021, 34(2):180-190]

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Cardiovascular events and all-cause mortality in surgically or medically treated primary aldosteronism: A Meta-analysis.

Ying Jing, Kangla Liao, Ruolin Li, Shumin Yang, Ying Song, Wenwen He, Kanran Wang, Jun Yang, Qifu Li, Jinbo Hu,

<h4>Objectives</h4>To compare the effect of surgical or medical treatment on the risk of cardiovascular diseases (CVD) and all-cause mortality in patients with established primary aldosteronism (PA).<h4>Methods</h4>We searched PUBMED, MEDLINE and Cochrane Library for the meta-analysis. We included patients who were diagnosed with PA following guideline-supported protocols and received surgery or ... Read more >>

J Renin Angiotensin Aldosterone Syst (Journal of the renin-angiotensin-aldosterone system : JRAAS)
[2021, 22(1):14703203211003781]

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HeRA: an atlas of enhancer RNAs across human tissues.

Zhao Zhang, Wei Hong, Hang Ruan, Ying Jing, Shengli Li, Yaoming Liu, Jun Wang, Wenbo Li, Lixia Diao, Leng Han,

Enhancer RNA (eRNA) is a type of long non-coding RNA transcribed from DNA enhancer regions. Despite critical roles of eRNA in gene regulation, the expression landscape of eRNAs in normal human tissue remains unexplored. Using numerous samples from the Genotype-Tissue Expression project, we characterized 45 411 detectable eRNAs and identified ... Read more >>

Nucleic Acids Res (Nucleic acids research)
[2021, 49(D1):D932-D938]

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Characterization of the dual functional effects of heat shock proteins (HSPs) in cancer hallmarks to aid development of HSP inhibitors.

Zhao Zhang, Ji Jing, Youqiong Ye, Zhiao Chen, Ying Jing, Shengli Li, Wei Hong, Hang Ruan, Yaoming Liu, Qingsong Hu, Jun Wang, Wenbo Li, Chunru Lin, Lixia Diao, Yubin Zhou, Leng Han,

<h4>Background</h4>Heat shock proteins (HSPs), a representative family of chaperone genes, play crucial roles in malignant progression and are pursued as attractive anti-cancer therapeutic targets. Despite tremendous efforts to develop anti-cancer drugs based on HSPs, no HSP inhibitors have thus far reached the milestone of FDA approval. There remains an unmet ... Read more >>

Genome Med (Genome medicine)
[2020, 12(1):101]

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Baseline immunity and impact of chemotherapy on immune microenvironment in cervical cancer.

Yi Zhang, Minhua Yu, Ying Jing, Jiejun Cheng, Caiyan Zhang, Lin Cheng, Haijiao Lu, Mei-Chun Cai, Jie Wu, Wenjing Wang, Weihua Lou, Lihua Qiu, Li Tan, Huaiwu Lu, Xia Yin, Guanglei Zhuang, Wen Di,

<h4>Background</h4>We aimed to comprehensively evaluate the immunologic landscape at baseline and upon chemotherapy in cervical cancer. The information should aid ongoing clinical investigations of checkpoint blockade immunotherapies in this disease setting.<h4>Methods</h4>A series of 109 cervical carcinoma patients was retrospectively assayed before and after neoadjuvant chemotherapy. Tumour-infiltrating immune markers (CD3, CD4, ... Read more >>

Br J Cancer (British journal of cancer)
[2021, 124(2):414-424]

Cited: 1 time

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Multi-omics prediction of immune-related adverse events during checkpoint immunotherapy.

Ying Jing, Jin Liu, Youqiong Ye, Lei Pan, Hui Deng, Yushu Wang, Yang Yang, Lixia Diao, Steven H Lin, Gordon B Mills, Guanglei Zhuang, Xinying Xue, Leng Han,

Immune-related adverse events (irAEs), caused by anti-PD-1/PD-L1 antibodies, can lead to fulminant and even fatal consequences and thus require early detection and aggressive management. However, a comprehensive approach to identify biomarkers of irAE is lacking. Here, we utilize a strategy that combines pharmacovigilance data and omics data, and evaluate associations ... Read more >>

Nat Commun (Nature communications)
[2020, 11(1):4946]

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Abnormal Dexamethasone Suppression Tests in a Rifapentine-Treated Patient With Primary Aldosteronism.

Hongman Wang, Ying Song, Zhixin Xu, Ying Jing, Wenwen He, Zhengping Feng, Qifu Li, Shumin Yang,

Aldosterone-producing adenoma (APA) is a main cause of primary aldosteronism (PA). Given that a large benign-appearing unilateral masse (>1 cm in diameter) may represent an aldosterone and cortisol-co-secreting adenoma, dexamethasone suppression testing is required in such patients to exclude or confirm the diagnosis of hypercortisolism. Tuberculosis is highly prevalent in ... Read more >>

Front Endocrinol (Lausanne) (Frontiers in endocrinology)
[2020, 11:593]

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The genetic and pharmacogenomic landscape of snoRNAs in human cancer.

Yaoming Liu, Hang Ruan, Shengli Li, Youqiong Ye, Wei Hong, Jing Gong, Zhao Zhang, Ying Jing, Xiulan Zhang, Lixia Diao, Leng Han,

Emerging evidence has revealed significant roles for small nucleolar RNAs (snoRNAs) in tumorigenesis. However, the genetic and pharmacogenomic landscape of snoRNAs has not been characterized. Using the genotype and snoRNA expression data from The Cancer Genome Atlas, we characterized the effects of genetic variants on snoRNAs across 29 cancer types ... Read more >>

Mol Cancer (Molecular cancer)
[2020, 19(1):108]

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Effects of total parathyroidectomy treatment on parathyroid hormone levels, recurrent laryngeal nerve function, and the rate of infection complications of secondary hyperparathyroidism patients under image information health monitoring by magnetic resonance imaging.

Fengyu Jia, Yan Xue, Kai Liu, Suxia Wang, Ying Jing, Dandan Li, Hanhui Zhao, Bo Li, Wenyuan Liu, Gang Sun,

In order to explore the application of computer information health monitoring technology in the evaluation of the treatment effect after total parathyroidectomy (T-PTX) for patients with Secondary Hyperparathyroidism (SHPT), preoperative magnetic resonance imaging (MRI) computer health monitoring technology was used to locate and diagnose the parathyroid glands. Autotransplantation were performed. ... Read more >>

Neurosci Lett (Neuroscience letters)
[2020, 735:135195]

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Sex-associated molecular differences for cancer immunotherapy.

Youqiong Ye, Ying Jing, Liang Li, Gordon B Mills, Lixia Diao, Hong Liu, Leng Han,

Immune checkpoint blockade therapies have extended patient survival across multiple cancer lineages, but there is a heated debate on whether cancer immunotherapy efficacy is different between male and female patients. We summarize the existing meta-analysis to show inconsistent conclusions for whether gender is associated with the immunotherapy response. We analyze ... Read more >>

Nat Commun (Nature communications)
[2020, 11(1):1779]

Cited: 12 times

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Driving GABAergic neurons optogenetically improves learning, reduces amyloid load and enhances autophagy in a mouse model of Alzheimer's disease.

Zijuan Zhang, Ying Jing, Yajing Ma, Dongxiao Duan, Bo Li, Christian Hölscher, Cheng Li, Jingwen Wei, Aishe Gao, Lizhi Shang, Feng Tao, Ying Xing,

The changes of local field potentials (LFP, mainly gamma rhythm and theta rhythm) in the brain are closely related to learning and memory formation. Reduced gamma rhythm (20-50 Hz) and theta rhythm (4-10 Hz) has been observed in the progression of Alzheimer's disease (AD), but it is not clear whether it is ... Read more >>

Biochem Biophys Res Commun (Biochemical and biophysical research communications)
[2020, 525(4):928-935]

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Microbiota and Chemical Compounds in Fermented Pinelliae Rhizoma (Banxiaqu) from Different Areas in the Sichuan Province, China.

B O Shu, Jing Ying, Tao Wang, Mengqian Xia, Wenyu Zhao, Ling You,

This study focused on the microbiota and chemical compounds of the fermented <i>Pinelliae Rhizoma</i> produced in Longchang (LC), Zizhong (ZZ) and Xindu (XD), in Sichuan Province (China). High-throughput sequencing was used to analyze the microbiota. GC-MS and LC-MS were used to detect the compounds produced during the three different <i>Pinelliae ... Read more >>

Pol J Microbiol (Polish journal of microbiology)
[2019, 68(1):83-92]

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High-Frequency rTMS of the Motor Cortex Modulates Cerebellar and Widespread Activity as Revealed by SVM.

Jue Wang, Xin-Ping Deng, Yun-Ying Wu, Xiao-Long Li, Zi-Jian Feng, Hong-Xiao Wang, Ying Jing, Na Zhao, Yu-Feng Zang, Jian Zhang,

Functional magnetic resonance imaging (fMRI) studies have shown that the effect of repetitive transcranial magnetic stimulation (rTMS) can induce changes in remote brain regions. In the stimulated regions, low-frequency (≤1 Hz) rTMS induces inhibitory effects, while high-frequency (≥5 Hz) stimulation induces excitatory effects. However, these stereotypical effects arising from low- ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2020, 14:186]

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Pregenual or subgenual anterior cingulate cortex as potential effective region for brain stimulation of depression.

Ying Jing, Na Zhao, Xin-Ping Deng, Zi-Jian Feng, Guo-Feng Huang, Meng Meng, Yu-Feng Zang, Jue Wang,

<h4>Background</h4>The dorsolateral prefrontal cortex (DLPFC) is the standard stimulation target for the repetitive transcranial magnetic stimulation (rTMS) treatment of major depression disorder (MDD). A retrospective study by Fox and colleagues found that a more negative resting-state functional magnetic resonance imaging (RS-fMRI) functional connectivity (FC) between left DLPFC and the subgenual ... Read more >>

Brain Behav (Brain and behavior)
[2020, 10(4):e01591]

Cited: 3 times

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Single-Cell Transcriptomic Atlas of Primate Ovarian Aging.

Si Wang, Yuxuan Zheng, Jingyi Li, Yang Yu, Weiqi Zhang, Moshi Song, Zunpeng Liu, Zheying Min, Huifang Hu, Ying Jing, Xiaojuan He, Liang Sun, Lifang Ma, Concepcion Rodriguez Esteban, Piu Chan, Jie Qiao, Qi Zhou, Juan Carlos Izpisua Belmonte, Jing Qu, Fuchou Tang, Guang-Hui Liu,

Molecular mechanisms of ovarian aging and female age-related fertility decline remain unclear. We surveyed the single-cell transcriptomic landscape of ovaries from young and aged non-human primates (NHPs) and identified seven ovarian cell types with distinct gene-expression signatures, including oocyte and six types of ovarian somatic cells. In-depth dissection of gene-expression ... Read more >>

Cell (Cell)
[2020, 180(3):585-600.e19]

Cited: 32 times

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[Risk factors for cow's milk protein allergy in infants: a multicenter survey].

Ji-Yong Zhang, Shao-Ming Zhou, Shao-Hua Wang, Feng-Xuan Sui, Wu-Hong Gao, Qing Liu, Hua-Bo Cai, Hong-Ying Jiang, Wei-Yan Li, Li-Ting Wang, Li Li, Wei Zhao, Jing Ying, Qian-Zhen Wu, Bi-Xia Weng, Yong-Mei Zeng,

OBJECTIVE:To investigate the risk factors for cow's milk protein allergy (CMPA) among infants through a multicenter clinical study. METHODS:A total of 1 829 infants, aged 1-12 months, who attended the outpatient service of the pediatric department in six hospitals in Shenzhen, China from June 2016 to May 2017 were enrolled as ... Read more >>

Zhongguo Dang Dai Er Ke Za Zhi (Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics)
[2020, 22(1):42-46]

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Abnormal Dexamethasone Suppression Tests in a Rifapentine-Treated Patient With Primary Aldosteronism

Hongman Wang, Ying Song, Zhixin Xu, Ying Jing, Wenwen He, Zhengping Feng, Qifu Li, Shumin Yang,

Aldosterone-producing adenoma (APA) is a main cause of primary aldosteronism (PA). Given that a large benign-appearing unilateral masse (>1 cm in diameter) may represent an aldosterone and cortisol-co-secreting adenoma, dexamethasone suppression testing is required in such patients to exclude or confirm the diagnosis of hypercortisolism. Tuberculosis is highly prevalent in ... Read more >>

Front Endocrinol (Lausanne) (Frontiers in endocrinology)
[2020, 11:]

Cited: 0 times

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