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Author Yin Feng Tan

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The gut microbiota confers the glucose-and lipid-lowering effect of Laurolitsine in db/db mice

Rui-qi Wang, Fang Zhang, Ya-nan Yang, Yin-feng Tan, Yong Zhang, Lin Dong, Ning Ma, Wei-ying Lu, Chong-ming Wu, Xiao-po Zhang,

<h4>Background: </h4> Modulations on gut microbiota by traditional Chinese medicines (TCMs) and their active components are emerging as potential therapeutic agents on diabetes. Litsea glutinosa is a TCM used in clinic to treat diabetes with alkaloids as the active constituents, and the Laurolitsine is the richest one. Purpose Based ... Read more >>

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Chemical Constituents and Anti-Gastric Ulcer Activity of Essential Oils of Alpinia officinarum (Zingiberaceae), Cyperus rotundus (Cyperaceae), and Their Herbal Pair.

Hui-Juan Qu, Kai-Wen Lin, Xiao-Liang Li, Hong-Ya Ou, Yin-Feng Tan, Mei Wang, Na Wei,

The essential oil (EO) of the herbal pair (HP), Alpinia officinarum-Cyperus rotundus (HP G-X) has been conventionally used in traditional Chinese medicine (TCM) for 'warming the stomach' and relieving pain. However, its pharmacologically active compounds, as well as the mechanism of its anti-gastric ulcer properties remain unclear. In this study, ... Read more >>

Chem Biodivers (Chemistry & biodiversity)
[2021, 18(10):e2100214]

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Determination of nootkatone in rat plasma by LC-tandem mass spectrometry and its application in a pharmacokinetic study.

Zhen-Miao Qin, Yong-Hui Li, Yin-Feng Tan, Hai-Long Li,

This study aimed to develop a rapid, sensitive, and specific LC-tandem mass spectrometry method for the determination of nootkatone in rat plasma. α-Cyperone was chosen as the internal standard (IS). The plasma was processed using a one-step acetonitrile protein precipitation method. Chromatographic separation of nootkatone was achieved on a Phenomenex ... Read more >>

Biomed Chromatogr (Biomedical chromatography : BMC)
[2021, 35(12):e5197]

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Effect of Alpina oxyphylla extract on streptozotocin-induced kidney injure via regulating TGF-β1 and MyD88.

Jiao-Xia Wu, An Jia, Yin-Feng Tan, Han Xu, Jian-Ping Tian, Yan Wang, Hai Long Li, Bing-Miao Gao, Yong-Hui Li,

<h4>Background</h4>Abnormal renal metabolism is closely related to the development of chronic kidney disease. It is well known that renal inflammation plays an important role in the occurrence and development of tubulointerstitial damage in the renal tubules. The purpose of the experiment was to observe the bioactivity of Alpina oxyphylla extract ... Read more >>

BMC Complement Med Ther (BMC complementary medicine and therapies)
[2020, 20(1):217]

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Simultaneous Measurement of Tadehaginoside and its Principal Metabolite in Rats by HPLC–MS/MS and its Application in Pharmacokinetics and Tissue Distribution Study

Cai-Yun Zhang, Ya-Ting Lu, Yin-Feng Tan, Lin Dong, Zhi-Heng Su, Xiao-Po Zhang,

<h4>Background: </h4> Tadehaginoside, an active ingredient isolated from Tadehagi triquetrum L., exhibited various biological activities. However, the pharmacokinetics and tissue-distribution which affects tadehaginoside’s therapeutic actions and application remain elusive.MethodsTo clarify the metabolism of tadehaginoside in vivo , a high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method was established to detect the ... Read more >>

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Development and validation of an LC-MS/MS method for the determination of DPHB in rat plasma and its application in pharmacokinetic studies.

Qi Wen, Hai-Long Li, Feng Chen, Jing-Wen Gong, Wei-Wei Guan, Nai-Guang Fu, Yin-Feng Tan,

The aim of the present study was to develop a rapid, specific and sensitive LC-MS/MS method for the determination of DPHB [7-(4″-hydroxy-3″-methoxyphenyl)-1-phenyl-4-hepten-3-one] in rat plasma using yakuchinone A as an internal standard (IS). n-Hexane was used for the extraction of DPHB from rat plasma. Chromatographic separation of DPHB was achieved ... Read more >>

Biomed Chromatogr (Biomedical chromatography : BMC)
[2018, 32(12):e4373]

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DIURETIC AND ANTI-DIURETIC BIOACTIVITY DIFFERENCES OF THE SEED AND SHELL EXTRACTS OF ALPINIA OXYPHYLLA FRUIT.

Yong-Hui Li, Yin-Feng Tan, Na Wei, Jun-Qing Zhang,

<h4>Background</h4>Alpinia oxyphylla fruit (AOF, Yizhi in Chinese) is a well-known traditional Chinese medicine as an anti-diuretic agent and composed of two parts <i>i.e</i>. seed and shell. These two parts have different components, but the bioactivity differences of the two parts are not clear. This study aims to evaluate the different ... Read more >>

Afr J Tradit Complement Altern Med (African journal of traditional, complementary, and alternative medicines : AJTCAM)
[2016, 13(5):25-32]

Cited: 1 time

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Measurement of pharmacokinetics and tissue distribution of three bioactive constituents from Zanthoxylum armatum DC in rat plasma and tissues through UFLC-MS/MS.

Yi-Ran Wang, Yong-Hui Li, Tao Guo, Hai-Long Li, Yin-Feng Tan, Zhong Zhang, Xu-Guang Zhang, Shi-Ying Mai, Jun-Qing Zhang,

The compounds of N-Methylanhydrotetrahydroberberrubine A, dictamnine and eudesmin were the primary bioactive components in the roots of Zanthoxylum armatum DC (Z. armatum). To clarify the pharmacokinetics and distribution of these three compounds, an ultra-fast liquid chromatography-tandem mass spectrometry (UFLC-MS/MS) was employed to determine the contents of these three compounds in ... Read more >>

J Chromatogr B Analyt Technol Biomed Life Sci (Journal of chromatography. B, Analytical technologies in the biomedical and life sciences)
[2018, 1087-1088:80-89]

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Effect of Alpinia officinarum Hance alcohol extracts on primary dysmenorrheal.

Ling Huang, Jun-Qing Zhang, You-Bin Li, Mi Liu, Hui-Ming Deng, Yu-Chao Luo, Yin-Feng Tan, Jie Hou, Gui-Wei Yao, Wei-Wei Guan,

<h4>Objective</h4>To study the effect of Alpinia officinarum Hance (A. officinarum) 80% alcohol extract on the primary dysmenorrhea.<h4>Methods</h4>A. officinarum 80% alcohol extract were enriched by macroporous adsorption resins. Female mice of primary dysmenorrhea model were established by oxytocin induction; the effects of A. officinarum 80% alcohol extract on primary dysmenorrhea were observed by body ... Read more >>

Asian Pac J Trop Med (Asian Pacific journal of tropical medicine)
[2016, 9(9):882-886]

Cited: 1 time

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Metabonomic study of the fruits of Alpinia oxyphylla as an effective treatment for chronic renal injury in rats.

Yong-Hui Li, Yin-Feng Tan, Hong-Die Cai, Jun-Qing Zhang,

Alpinia oxyphylla (Zingiberaceae) is a well-known medicinal plant. Its fruit ("Yi-Zhi-Ren" in Chinese) is used as an anti-diuretic and traditionally used for the treatment of enuresis and reduce urination. Chronic kidney disease (CKD) is a disease with the characteristic of the slowly loss of kidney function and has a prevalence ... Read more >>

J Pharm Biomed Anal (Journal of pharmaceutical and biomedical analysis)
[2016, 124:236-245]

Cited: 3 times

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Could the gut microbiota reconcile the oral bioavailability conundrum of traditional herbs?

Feng Chen, Qi Wen, Jun Jiang, Hai-Long Li, Yin-Feng Tan, Yong-Hui Li, Nian-Kai Zeng,

<h4>Ethnopharmacological relevance</h4>A wealth of information is emerging about the impact of gut microbiota on human health and diseases such as cardiovascular diseases, obesity and diabetes. As we learn more, we find out the gut microbiota has the potential as new territory for drug targeting. Some novel therapeutic approaches could be ... Read more >>

J Ethnopharmacol (Journal of ethnopharmacology)
[2016, 179:253-264]

Cited: 34 times

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Differential systemic exposure to galangin after oral and intravenous administration to rats.

Feng Chen, Yin-Feng Tan, Hai-Long Li, Zhen-Miao Qin, Hong-Die Cai, Wei-Yong Lai, Xiao-Po Zhang, Yong-Hui Li, Wei-Wei Guan, You-Bin Li, Jun-Qing Zhang,

<h4>Background</h4>Galangin (3,5,7-trihydroxyflavone) is present in high concentrations in herbal medicine such as Alpinia officinarum Hance. Galangin shows multifaceted in vitro and in vivo biological activities. The number and position of hydroxyl groups in this molecule play an important role in these biological activities. However, these hydroxyl groups undergo glucuronidation and ... Read more >>

Chem Cent J (Chemistry Central journal)
[2015, 9:14]

Cited: 5 times

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Izalpinin from fruits of Alpinia oxyphylla with antagonistic activity against the rat bladder contractility.

Yuan Yuan, Yin-Feng Tan, Peng Xu, Hailong Li, Yong-Hui Li, Wen-Ya Chen, Jun-Qing Zhang, Feng Chen, Guo-Jun Huang,

<h4>Background</h4>Alpinia oxyphylla (Zingiberaceae), an herbaceous perennial plant, its capsular fruit is commonly used in traditional Chinese medicine for the treatment of different urinary incontinence symptoms including frequency, urgency and nocturia. These symptoms are similar to the overactive bladder syndrome. In our lab, we found that the 95% ethanol extract of ... Read more >>

Afr J Tradit Complement Altern Med (African journal of traditional, complementary, and alternative medicines : AJTCAM)
[2014, 11(4):120-125]

Cited: 2 times

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Identification of known chemicals and their metabolites from Alpinia oxyphylla fruit extract in rat plasma using liquid chromatography/tandem mass spectrometry (LC-MS/MS) with selected reaction monitoring.

Feng Chen, Hai-Long Li, Yin-Feng Tan, Yong-Hui Li, Wei-Yong Lai, Wei-Wei Guan, Jun-Qing Zhang, Yuan-Sheng Zhao, Zhen-Miao Qin,

Alpinia oxyphylla (Yizhi) capsularfruits are commonly used in traditional medicine. Pharmacological studies have demonstrated that A. oxyphylla capsularfruits have some beneficial roles. Besides volatile oil, sesquiterpenes, diarylheptanoids and flavonoids are main bioactive constituents occurring in the Yizhi capsularfruits. The representative constituents include tectochrysin, izalpinin, chrysin, apigenin-4',7-dimethylether, kaempferide, yakuchinone A, yakuchinone ... Read more >>

J Pharm Biomed Anal (Journal of pharmaceutical and biomedical analysis)
[2014, 97:166-177]

Cited: 9 times

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Crude dietary polysaccharide fraction isolated from jackfruit enhances immune system activity in mice.

Yin-Feng Tan, Hai-Long Li, Wei-Yong Lai, Jun-Qing Zhang,

Crude polysaccharides (PSs) were isolated from the fruit pulp of jackfruit, and their chemical composition determined and evaluated for an immune regulatory activity in mice. The PSs were isolated from water extracts of jackfruit pulp (JFP) using the ethanol precipitation method. The resulting precipitates were further purified by dialysis and ... Read more >>

J Med Food (Journal of medicinal food)
[2013, 16(7):663-668]

Cited: 3 times

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Urinary trichloroacetic acid levels and semen quality: a hospital-based cross-sectional study in Wuhan, China.

Shao-Hua Xie, Yu-Feng Li, Yin-Feng Tan, Dan Zheng, Ai-Lin Liu, Hong Xie, Wen-Qing Lu,

Toxicological studies indicate an association between exposure to disinfection by-products (DBPs) and impaired male reproductive health in animals. However, epidemiological evidence in humans is still limited. We conducted a hospital-based cross-sectional study to investigate the effect of exposure to DBPs on semen quality in humans. Between May 2008 and July ... Read more >>

Environ Res (Environmental research)
[2011, 111(2):295-300]

Cited: 11 times

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