Full Text Journal Articles by
Author Yibo Dai

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Tumor Molecular Features Predict Endometrial Cancer Patients' Survival After Open or Minimally Invasive Surgeries.

Yibo Dai, Jingyuan Wang, Luyang Zhao, Zhiqi Wang, Jianliu Wang,

<h4>Background</h4>The Cancer Genome Atlas (TCGA) project shed light on the vital role of tumor molecular features in predicting endometrial cancer patients' prognosis. This study aims to investigate the survival impact of surgical approaches on patients with different genetic alterations.<h4>Methods</h4>473 endometrial cancer patients from TCGA database were selected. To analyze the ... Read more >>

Front Oncol (Frontiers in oncology)
[2021, 11:634857]

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Identification of an immune-related risk signature and nomogram predicting the overall survival in patients with endometrial cancer.

Yuan Cheng, Xingchen Li, Yibo Dai, Yangyang Dong, Xiao Yang, Jianliu Wang,

<h4>Objective</h4>Aimed to construct an immune-related risk signature and nomogram predicting endometrial cancer (EC) prognosis.<h4>Methods</h4>An immune-related risk signature in EC was constructed using the least absolute shrinkage and selection operator regression analysis based on The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases. A nomogram integrating the immune-related genes ... Read more >>

J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(3):e30]

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Bone Metastases of Endometrial Carcinoma Treated by Surgery: Report on 13 Patients and Review of The Medical Literature

Jingyuan Wang, Yibo Dai, Tao Ji, Wei Guo, Zhiqi Wang, Jianliu Wang,

<h4>Objective: </h4> The aim of this study was to describe the clinicopathological features of EC patients with bone metastases treated with surgery and to systematically review the literature. <h4>Methods: </h4> We performed a retrospective study to include patients with bone metastases of EC at Peking University People’s Hospital during 2000 ... Read more >>

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Novel Small Molecular Compound AE-848 Potently Induces Human Multiple Myeloma Cell Apoptosis by Modulating the NF-κB and PI3K/Akt/mTOR Signaling Pathways.

Yaqi Xu, Xiaoli Feng, Qian Zhou, Wen Jiang, Yibo Dai, Yang Jiang, Xiaoli Liu, Shuo Li, Yongjing Wang, Fang Wang, Ai Li, Chengyun Zheng,

<h4>Background</h4>We aimed to investigate the anti-multiple myeloma (MM) activity of the new small molecular compound AE-848 (5-bromo-2-hydroxyisophthalaldehyde bis[(1-methyl-1H-benzimidazol-2-yl)hydrazone]) and its underlying anti-MM mechanism.<h4>Methods</h4>Cell viability and apoptosis were detected and quantified by using MTT and flow cytometry, respectively. JC-1 dye-related techniques were used to assess mitochondrial membrane potential (MMP). Western blotting ... Read more >>

Onco Targets Ther (OncoTargets and therapy)
[2020, 13:13063-13075]

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Microstructure and Wear Resistance of Multi-Layer NI-Based Alloy Cladding Coating on 316l SS Under Different Laser Power

Qian Shaoxiang, Zhang Yongkang, Dai Yibo, Guo Yuhang,

Three kinds of Ni based alloy cladding coatings were prepared on 316L stainless steel at different power. The microstructure of the cladding layer was observed and analyzed by XRD, metallographic microscope and SEM. The hardness of the cladding layer was measured, and the wear resistance of the cladding layer was ... Read more >>

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Survival of microsatellite-stable endometrioid endometrial cancer patients after minimally invasive surgery: An analysis of the Cancer Genome Atlas data.

Yibo Dai, Zhiqi Wang, Jianliu Wang,

<h4>Objective</h4>This study aims to investigate the survival impact of minimally invasive surgery on endometrial cancer (EC) patients with different histology and microsatellite status.<h4>Methods</h4>This is a retrospective study based on the Cancer Genome Atlas (TCGA) data. 519 eligible EC patients were divided into four subgroups according to histology and microsatellite status. ... Read more >>

Gynecol Oncol (Gynecologic oncology)
[2020, 158(1):92-98]

Cited: 1 time

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Disulfiram/copper markedly induced myeloma cell apoptosis through activation of JNK and intrinsic and extrinsic apoptosis pathways.

Yaqi Xu, Qian Zhou, Xiaoli Feng, Yibo Dai, Yang Jiang, Wen Jiang, Xiaoli Liu, Xiangling Xing, Yongjing Wang, Yihong Ni, Chengyun Zheng,

Disulfiram (DSF) is an FDA approved anti-alcoholism drug in use for more than 60 years. Recently, antitumor activity of the DSF/copper (DSF/Cu) complex has been identified. Its anti-multiple myeloma activity, however, has barely been investigated. In the present study, our results demonstrated that the DSF/Cu complex induced apoptosis of MM ... Read more >>

Biomed Pharmacother (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie)
[2020, 126:110048]

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Prognostic significance of lymphovascular space invasion in patients with endometrioid endometrial cancer: a retrospective study from a single center.

Yibo Dai, Yangyang Dong, Yuan Cheng, Hongyi Hou, Jingyuan Wang, Zhiqi Wang, Jianliu Wang,

OBJECTIVE:This study aims to analyze factors associated with lymphovascular space invasion (LVSI) and evaluate the prognostic significance of LVSI in Chinese endometrioid endometrial cancer (EEC) patients. METHODS:Five-hundred eighty-four EEC patients undergoing surgery in our center from 2006 to 2016 were selected for analysis. Univariate analysis and multivariate logistic regression were ... Read more >>

J Gynecol Oncol (Journal of gynecologic oncology)
[2020, 31(3):e27]

Cited: 1 time

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Mesenchymal stem cells significantly improved treatment effects of Linezolid on severe pneumonia in a rabbit model.

Dexiao Kong, Xia Liu, Xiaomei Li, Jianting Hu, Xiaoyan Li, Juan Xiao, Yibo Dai, Mingming He, Xiaoli Liu, Yang Jiang, Ruodi Cui, Lihong Zhang, Juandong Wang, Ai Li, Fang Wang, Yuan Zhang, Juan Xiao, Wei Wang, Chengyun Zheng,

The present study aimed to investigate whether co-administration of mesenchymal stromal cells (MSC) and linezolid (LZD) into a rabbit model of methicillin-resistant Staphylococcus aureus (MRSA)-infected pneumonia would bring a synergistic therapeutic effect. Human umbilical cord-derived MSCs (hUMSCs) were isolated and characterized. A rabbit model of pneumonia was constructed by delivering ... Read more >>

Biosci Rep (Bioscience reports)
[2019, 39(9):]

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AK-968 efficiently inhibits proliferation and induces cell apoptosis in human multiple myeloma cells.

Yibo Dai, Yaq Xu, Yang Jiang, Wen Jiang, Xiaoli Liu, Chengyun Zhang,

AK-968 is a small molecular weight compound. In this study, we evaluated its anti-tumor effects on human multiple myeloma (MM) cells. Our results demonstrated that AK-968 markedly inhibited proliferation of MM cell lines in a dose-and time-dependent manner. Additionally, our flow cytometry data showed that MM cell apoptosis was significantly ... Read more >>

Pharmazie (Die Pharmazie)
[2019, 74(3):150-153]

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Ovarian stimulated cycle: not a better alternative for women without ovulation disorder in intrauterine insemination.

Kemei Zhang, Yinjiao Shi, Ensheng Wang, Li Wang, Qingbo Hu, Yibo Dai, Haiyan Xu, Jiaou Zhang, Ping Jin, Xueqin Chen, Jing Shu,

To explore the related factors on the clinical pregnancy outcome in intrauterine insemination, a retrospective study was conducted on the clinical data of 580 cycles for 301 infertile couples who were treated with intrauterine insemination. The female age, male age, duration of infertility, treatment protocols, endometrial thickness and sperm parameters ... Read more >>

Oncotarget (Oncotarget)
[2017, 8(59):100773-100780]

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HDAC8 functions in spindle assembly during mouse oocyte meiosis.

Kemei Zhang, Yajuan Lu, Chaohua Jiang, Wei Liu, Jing Shu, Xueqin Chen, Yingjiao Shi, Ensheng Wang, Li Wang, Qinbo Hu, Yibo Dai, Bo Xiong,

HDAC8 is a class I histone deacetylase that functions in a variety of biological processes through its non-histone substrates. However, its roles during oocyte meiosis remain elusive. Here, we document that HDAC8 localizes at spindle poles and positively participates in the regulation of microtubule organization and spindle assembly in mouse ... Read more >>

Oncotarget (Oncotarget)
[2017, 8(12):20092-20102]

Cited: 6 times

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Automatic traction device for neurosurgical operation

LIANGFU ZHOU, YING MAO, RONG ZHANG, CHENGJUN YAO, JINSONG WU, DONGXIAO ZHUANG, YIBO DAI,

An automatic traction device for a neurosurgical operation is connected with a dedicated headstock for the magnetic resonance navigation, and comprises an adapter, a connector, a connecting piece, a C-shaped arm, a snakelike arm and a brain spatula which are connected in sequence. The adapter, the connector, the connecting piece, ... Read more >>

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Automatic traction device for neurosurgical operation

YIBO DAI, YING MAO, JINSONG WU, CHENGJUN YAO, RONG ZHANG, LIANGFU ZHOU, DONGXIAO ZHUANG,

The invention relates to an automatic traction device for a neurosurgical operation, which is used for being connected to a special headrest for magnetic resonance navigation and comprises a connector, a connecting member, a C-shaped arm, a snakelike arm and a brain spatula which are connected in sequence, wherein the ... Read more >>

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Auxiliary device for transnasal-sphenoidal neurosurgery

YIBO DAI, YING MAO, JINSONG WU, CHENGJUN YAO, LIANGFU ZHOU, DONGXIAO ZHUANG,

The invention relates to an auxiliary device for transnasal-sphenoidal neurosurgery, comprising a nasal speculum and a navigation microprobe, wherein the navigation microprobe comprises a miniature handle and a microballoon connected at the front end of the handle and put in an operated cavity through the nasal speculum when magnetic resonance ... Read more >>

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Auxiliary device for endonasal transsphenoidal neurosurgical operation

JINSONG WU, LIANGFU ZHOU, CHENGJUN YAO, YING MAO, DONGXIAO ZHUANG, YIBO DAI,

An auxiliary device for an endonasal transsphenoidal neurosurgical operation comprises a nasal endoscopy and a navigation miniature probe. The navigation miniature probe consists of a miniature handle and a miniature ball connected to the front end of the handle, and is put in an operation cavity when the magnetic resonance ... Read more >>

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