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Author Yi Zhou

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Solid-phase synthesis of peptide Mn(i)-carbonyl bioconjugates and their CO release upon visible light activation.

Yi Zhou, Yonglu Chen, Chunmao He,

A one-pot synthetic route has been developed for the assembly of peptide Mn(i)-carbonyl bioconjugates. It allows the installation of a variety of chelating agents at the late stage, and after just one purification step the TAT-MnCO complexes can be obtained. The resulting bioconjugates showed different and tunable CO releasing kinetics ... Read more >>

Dalton Trans (Dalton transactions (Cambridge, England : 2003))
[2021, 50(12):4231-4236]

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Notum palmitoleoyl-protein carboxylesterase regulates Fas cell surface death receptor-mediated apoptosis via the Wnt signaling pathway in colon adenocarcinoma.

Hua Gong, Qiang Niu, Yi Zhou, Yun-Xia Wang, Xuan-Fu Xu, Ke-Zhu Hou,

Colon adenocarcinoma (COAD) is one of the most common types of malignancy and accounts for >3 million deaths worldwide each year. The present study aimed to evaluate the role of notum palmitoleoyl-protein carboxylesterase (NOTUM) in <i>in vivo</i> and <i>in vitro</i>, and to identify the relationship between NOTUM and the apoptosis ... Read more >>

Bioengineered (Bioengineered)
[2021, 12(1):5241-5252]

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Correction to: Synthesis and evaluation of iridium(III) complexes on antineoplastic activity against human gastric carcinoma SGC‑7901 cells.

Li Tian, Yuanyuan Zhang, Huiwen Zhang, Yi Zhou, Wenlong Li, Yuhan Yuan, Jing Hao, Linlin Yang, Yunjun Liu,

J Biol Inorg Chem (Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry)
[2021, 26(8):973]

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Mycoplasma ovipneumoniae induces caspase-8-dependent extrinsic apoptosis and p53- and ROS-dependent intrinsic apoptosis in murine alveolar macrophages.

Jing Chen, Yi Zhou, Erpeng Zhu, Peng Yang, Mei Li, Shuangxiang Zhang, Jun Yue, Ming Wen, Kaigong Wang, Zhentao Cheng,

<i>Mycoplasma ovipneumoniae (MO)</i> is a principle causative agent of chronic respiratory disease in ruminants, including sheep, goats, and deer, posing a great threat to the ruminant industry worldwide. However, the pathogenesis of <i>MO</i> infection still remains not well understood and needs further clarification. Here we report a time-dependent apoptosis in ... Read more >>

Virulence (Virulence)
[2021, 12(1):2703-2720]

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By targeting apoptosis facilitator BCL2L13, microRNA miR-484 alleviates cerebral ischemia/reperfusion injury-induced neuronal apoptosis in mice.

Xindong Liu, Xin Wang, Lijuan Zhang, Yi Zhou, Le Yang, Minghao Yang,

Neuronal apoptosis was considered as one of the main factors of cerebral ischemia/reperfusion injury. Understanding the molecular regulatory mechanism of neuronal apoptosis under the cerebral ischemia/reperfusion injury may provide the novel therapeutic targets for cerebral ischemia/reperfusion injury. However, the molecular regulatory mechanism of neurons fate determination under the cerebral ischemia/reperfusion ... Read more >>

Bioengineered (Bioengineered)
[2021, 12(1):948-959]

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Changes in bone graft height and influencing factors after sinus floor augmentation by using the lateral window approach: A clinical retrospective study of 1 to 2 years.

Xiaoxu Guan, Jiawei Zhang, Yao Chen, Jie Han, Mengfei Yu, Yi Zhou,

Recent systematic reviews have reported resorption of bone grafts after augmentation, but the influencing factors are numerous and uncertain. Different brands of bone graft and other factors may affect the bone formation effect after sinus floor augmentation. The purpose of this retrospective clinical study was to evaluate the graft material ... Read more >>

J Prosthet Dent (The Journal of prosthetic dentistry)
[2021, :]

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Bursty gene expression and mRNA decay pathways orchestrate B cell activation.

Yi Zhou, Cornelis Murre,

[Figure: see text]. ... Read more >>

Sci Adv (Science advances)
[2021, 7(49):eabm0819]

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ThGM Cells as a Prognostic and Predictive Marker for Coronary Heart Disease

Dachao Mou, Shasha Wu, Ling Jiao, Yi Zhou, Xiufeng Bai,

<h4>Background: </h4> Coronary heart disease (CHD) is causing by the aberrant aggregation of immune cells in plaque. This study aimed to identify abnormal T cell subtypes and inflammatory factors in CHD patients. <h4>Methods: </h4> and results T cell subsets from 187 CHD patients were analyzed using flow cytometry. Plasma concentration ... Read more >>

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Human umbilical cord-derived mesenchymal stem cells improve chronic pancreatitis in rats via the AKT-mTOR-S6K1 signaling pathway.

Lijun Kong, Xiangxiang Xu, Hewei Zhang, Yi Zhou, Hongjian Huang, Bicheng Chen, Zhenxu Zhou,

Chronic pancreatitis (CP) is a progressive inflammatory disease. In clinical treatment, many patients cannot get a timely diagnosis and effective treatment due to the lack of early diagnosis indicators. Mesenchymal stem cells have immunomodulatory and anti-inflammatory effects, and have broad application prospects in treating auto-immune diseases and inflammatory diseases. This ... Read more >>

Bioengineered (Bioengineered)
[2021, 12(1):1986-1996]

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Gastrointestinal Tract Lymphomas.

Jessica Alvarez-Lesmes, Jennifer R Chapman, Daniel Cassidy, Yi Zhou, Monica Garcia-Buitrago, Elizabeth A Montgomery, Izidore S Lossos, Daniel Sussman, Julio Poveda,

<h4>Context.—</h4>The gastrointestinal (GI) tract is the most common site of extranodal non-Hodgkin lymphoma, accounting for 20% to 40% of all extranodal lymphomas. The majority of these are systemic processes secondarily involving the GI tract. Primary GI lymphomas are less common, accounting for approximately 10% to 15% of all non-Hodgkin lymphomas. ... Read more >>

Arch Pathol Lab Med (Archives of pathology & laboratory medicine)
[2021, 145(12):1585-1596]

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Are we there yet? A machine learning architecture to predict organotropic metastases.

Michael Skaro, Marcus Hill, Yi Zhou, Shannon Quinn, Melissa B Davis, Andrea Sboner, Mandi Murph, Jonathan Arnold,

<h4>Background & aims</h4>Cancer metastasis into distant organs is an evolutionarily selective process. A better understanding of the driving forces endowing proliferative plasticity of tumor seeds in distant soils is required to develop and adapt better treatment systems for this lethal stage of the disease. To this end, we aimed to ... Read more >>

BMC Med Genomics (BMC medical genomics)
[2021, 14(1):281]

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Screening of bioactive ingredients of Tsantan Sumtang in ameliorating H9c2 cells injury.

Yi Zhou, Zhanqiang Li, Dejun Zhang, Benyin Zhang,

<h4>Ethnopharmacological relevance</h4>Tsantan Sumtang (TS), a traditional Tibetan medicine, has been used in the clinic for the treatment of myocardial ischemia (MI) for ages, however, the bioactive ingredients that are responsible for improving MI remain unknown.<h4>Aim of the study</h4>This study investigated the chemical components of TS and their medicinal efficacies at ... Read more >>

J Ethnopharmacol (Journal of ethnopharmacology)
[2021, :114854]

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Pay-it-forward to improve influenza vaccine uptake and public engagement among children and older adults in China: A three-arm quasi-experimental study

Dan Wu, Chenqi Jin, Khaoula Bessame, Fanny Tang, Jason Ong, Zaisheng Wang, Yewei Xie, Mark Jit, Heidi Larson, Tracey Chantler, Leesa Lin, Wenfeng Gong, Fan Yang, Fengshi Jing, Shufang Wei, Weibin Cheng, Yi Zhou, Nina Ren, Shuhao Qiu, Jianmin Bao, Liufen Wen, Qinlu Yang, Junzhang Tian, Weiming Tang, Joseph Tucker,

China has low seasonal influenza vaccination rates among children and older adults. This quasi-experimental pragmatic trial examined the effectiveness of a pay-it-forward intervention on influenza vaccination compared to standard of care (user-paid vaccination) and free vaccination strategies among children and older people in China (ChiCTR2000040048). In pay-it-forward, people receive a ... Read more >>

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Optimal resource allocation in HIV self-testing secondary distribution among Chinese MSM: data-driven integer programming models.

Fengshi Jing, Qingpeng Zhang, Jason J Ong, Yewei Xie, Yuxin Ni, Mengyuan Cheng, Shanzi Huang, Yi Zhou, Weiming Tang,

Human immunodeficiency virus self-testing (HIVST) is an innovative and effective strategy important to the expansion of HIV testing coverage. Several innovative implementations of HIVST have been developed and piloted among some HIV high-risk populations like men who have sex with men (MSM) to meet the global testing target. One innovative ... Read more >>

Philos Trans A Math Phys Eng Sci (Philosophical transactions. Series A, Mathematical, physical, and engineering sciences)
[2022, 380(2214):20210128]

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Modelling the geographical spread of HIV among MSM in Guangdong, China: a metapopulation model considering the impact of pre-exposure prophylaxis.

Fengshi Jing, Yang Ye, Yi Zhou, Hanchu Zhou, Zhongzhi Xu, Ying Lu, Xiaoyu Tao, Shujuan Yang, Weibin Cheng, Junzhang Tian, Weiming Tang, Dan Wu,

Men who have sex with men (MSM) make up the majority of new human immunodeficiency virus (HIV) diagnoses among young people in China. Understanding HIV transmission dynamics among the MSM population is, therefore, crucial for the control and prevention of HIV infections, especially for some newly reported genotypes of HIV. ... Read more >>

Philos Trans A Math Phys Eng Sci (Philosophical transactions. Series A, Mathematical, physical, and engineering sciences)
[2022, 380(2214):20210126]

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Therapeutic Nucleus-Access BNCT Drug Combined CD47-Targeting Gene Editing in Glioblastoma

Jiejian Chen, Qi Dai, QiYao Yang, Xiaoyan Bao, Yi Zhou, Haiqing Zhong, Linjie Wu, Tiantian Wang, Zhicheng Zhang, Yiying Lu, Zhentao Zhang, Mengting Lin, Min Han, Qichun Wei,

Glioblastoma is the most common brain primary malignant tumor with the highest mortality. Boron neutron capture therapy (BNCT) can efficiently kill cancer cells on the cellular scale, with high accuracy, short course and low side-effects, which is regarded as the most promising therapy for malignant brain tumors like glioma. As ... Read more >>

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The prognostic significance of white blood cell and platelet count for in-hospital mortality and pneumonia in acute ischemic stroke.

Shoujiang You, Xin Sun, Yi Zhou, Chongke Zhong, Juping Chen, Wanqing Zhai, Yongjun Cao,

<h4>Background</h4>We investigated the combined effect of white blood cell (WBC) and platelet count on in-hospital mortality and pneumonia in acute ischemic stroke (AIS) patients.<h4>Methods</h4>A total of 3,265 AIS patients enrolled from December 2013 to May 2014 across 22 hospitals in Suzhou city were included in the present study. We divided ... Read more >>

Curr Neurovasc Res (Current neurovascular research)
[2021, :]

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Corrigendum to "Insulin exacerbated high glucose-induced epithelial-mesenchymal transition in prostatic epithelial cells BPH-1 and prostate cancer cells PC-3 via MEK/ERK signaling pathway" [Exp. Cell Res. 394 (1) (2020 Sep 1) 112145].

Tingting Yang, Yi Zhou, Haiyan Wang, Shangxiu Chen, Mengli Shen, Yinlu Hu, Tao Wang, Junjie Liu, Zhenzhou Jiang, ZhongJian Wang, Xia Zhu, Sitong Qian, Xiaoxing Yin, Qian Lu,

Exp Cell Res (Experimental cell research)
[2021, 409(2):112923]

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Event-Based Motion Segmentation With Spatio-Temporal Graph Cuts.

Yi Zhou, Guillermo Gallego, Xiuyuan Lu, Siqi Liu, Shaojie Shen,

Identifying independently moving objects is an essential task for dynamic scene understanding. However, traditional cameras used in dynamic scenes may suffer from motion blur or exposure artifacts due to their sampling principle. By contrast, event-based cameras are novel bio-inspired sensors that offer advantages to overcome such limitations. They report pixel-wise ... Read more >>

IEEE Trans Neural Netw Learn Syst (IEEE transactions on neural networks and learning systems)
[2021, PP:]

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Etiology spectrum and clinical characteristics of renal artery stenosis in a Chinese cohort.

Xu Meng, Yi Zhou, Xiong-Jing Jiang, Jun Cai, Hui-Min Zhang, Hai-Ying Wu, Wen-Jun Ma, Ying Lou, Ya-Xin Liu, Xian-Liang Zhou,

<h4>Objective</h4>To analyze the causes of renal artery stenosis (RAS) and compare the clinical characteristics in accordance with the primary disease among patients aged from 30 to 50.<h4>Methods</h4>Patients were grouped by etiologies of RAS. Groups were retrospectively examined and compared regarding demographic data, clinical manifestations, laboratory findings, and imaging findings.<h4>Results</h4>A total ... Read more >>

J Geriatr Cardiol (Journal of geriatric cardiology : JGC)
[2021, 18(2):104-113]

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Ursodeoxycholic Acid Exhibits Anti-inflammatory Activity against Concanavalin A-induced Immune Hepatitis in Mice

Guixian Ji, Man Liu, Yi Zhou, Weilong Zhong, Xiaoyi Wang, Hongyu Chu, Xin Liu, Maimaitiabudu Maimaitiaili, Bangmao Wang, Lu Zhou,

<h4>Objective: </h4> It was to evaluate the anti-inflammatory effect of ursodeoxycholic acid (UDCA) on concanavalin A (ConA)-induced immune hepatitis in mice and determine the molecular mechanism. MethodsFemale C57BL/6J mice were randomly classified into Control, ConA, and ConA+UDCA groups. Serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels were measured. Quantitative ... Read more >>

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Rhophilin rho GTPase binding protein 1-antisense RNA 1 (RHPN1-AS1) promotes ovarian carcinogenesis by sponging microRNA-485-5p and releasing DNA topoisomerase II alpha (TOP2A).

Yi Zhou, Jing Li, Xiaoxin Yang, Yu Song, Haigang Li,

Ovarian cancer (OC) is the most common and lethal gynecological cancer worldwide. Long non-coding RNAs (lncRNAs) and sponging microRNAs (miRNAs) serve as key regulators in the biological processes of OC. We sought to evaluate the effect of the RHPN1-AS1-miR-485-5p-DNA topoisomerase II alpha (TOP2A) axis in regulating OC progression. RHPN1-AS1, miR-485-5p, ... Read more >>

Bioengineered (Bioengineered)
[2021, :]

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Anatomical Boundaries in Plant Roots Form Important Barriers for Selection of the Soil Microbiome

Yi Zhou, Yanli Wei, Zhongjuan Zhao, Jishun Li, Hongmei Li, Peizhi Yang, Shenzhong Tian, Maarten Ryder, Ruey Toh, Hetong Yang, Matthew Denton,

<h4>Background: </h4> The microbiome in plant-soil systems has a significant influence in promoting plant growth. The extent of selectivity that the plant exerts on the microbiome in the continuum of internal plant tissues is not well understood. This study analysed the root microbiome of a legume, Melilotus officinalis (L.) Pall., ... Read more >>

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Is Anti-HMGB1 Antibody a Potential Characteristic Autoantibody for Sjögren's Syndrome?

Mingkun Chen, Yi Zhou, Miao Xue, Rongrong Zhu, Liling Jing, Liling Lin, Chengwen He, Yanghua Qin,

BACKGROUND: Sjögren's syndrome (SS) is a common chronic inflammatory autoimmune disease, affects about 0.33% to 0.77% population in China. The positive for antinuclear antibodies (ANA) is one of the key features of SS, which show typical granular pattern in indirect immunofluorescent antibody test (IIFT). About 70% SS patients have the ... Read more >>

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Aridification in a farming-pastoral ecotone of northern China from 2 perspectives: Climate and soil.

Guoliang Zhang, Xin Chen, Yi Zhou, Li Jiang, Yuling Jin, Yukai Wei, Yunpeng Li, Zhihua Pan, Pingli An,

Understanding the impact of climate change on terrestrial wet and dry changes and the relationship between the two is of great significance to the sustainable development of terrestrial ecosystems. The farming-pastoral ecotone of northern China (FPENC) is an area that is sensitive to climate change, suffering from perennial drought and ... Read more >>

J Environ Manage (Journal of environmental management)
[2021, 302(Pt B):114070]

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