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Transforming sustained release into on-demand release: self-healing guanosine-borate supramolecular hydrogels with multiple responsiveness for Acyclovir delivery.

Cheng-Guang Wu, Xiang Wang, Yun-Feng Shi, Bin-Cheng Wang, Wei Xue, Yi Zhang,

Supramolecular hydrogels derived from natural biomolecules have promising applications for drug delivery due to their inherent biocompatibility and tunable responsiveness to various stimuli. However, conventional hydrogels only modulate the release kinetics roughly to achieve sustained drug release, exhibiting fast-then-slow release behavior without on/off control. Herein, a guanosine (G)-quartet·Na+-borate supramolecular hydrogel ... Read more >>

Biomater Sci (Biomaterials science)
[2020, 8(22):6190-6203]

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A perylene diimide-containing acceptor enables high fill factor in organic solar cells.

Kui Ding, Tong Shan, Jinqiu Xu, Mengyang Li, Yan Wang, Yi Zhang, Ziyi Xie, Zaifei Ma, Feng Liu, Hongliang Zhong,

A new non-fullerene acceptor PDFC is prepared by introducing perylene diimide into the core of an A-DA'D-A architecture. Due to the large conjugation and electron-deficient ability of perylene diimide, PDFC shows strong absorption, suitable energy levels and favorable face-on packing. The optimal device realizes a PCE of 12.56% with one ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2020, 56(77):11433-11436]

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Amphiphilic BODIPY dye aggregates in polymeric micelles for wavelength-dependent photo-induced cancer therapy.

Ziling Yan, Mengya Wang, Mengke Shi, Yang He, Yi Zhang, Shihong Qiu, Hong Yang, Huabing Chen, Hui He, Zhengqing Guo,

Near-infrared (NIR) light-responsive nanoparticles of organic small-molecule dyes hold great promise as phototherapeutic dyes (PDs) for clinical translation due to their intrinsic merits, including well-defined structure, high purity, and good reproducibility. However, they have been explored with limited success in the development of photostable NIR PDs with extraordinary photoconversion for ... Read more >>

J Mater Chem B (Journal of materials chemistry. B)
[2020, 8(31):6886-6897]

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Mitochondrion-targeting chemiluminescent ternary supramolecular assembly for in situ photodynamic therapy.

Lei Chen, Yong Chen, Weilei Zhou, Jingjing Li, Yi Zhang, Yu Liu,

The development of smart supramolecular self-assemblies for photodynamic therapy (PDT) and organelle-targeting cell imaging has become a hot topic of research due to their rapid and intelligent responses. Herein, we report a novel ternary supramolecular assembly of nanoparticles, composed specifically of photosensitizer molecules 4,4'-(dibenzo[a,c]phenazine-9,14-diyl)pyridin-1-ium bromide (DPAC-S) and cucurbit[7]uril (CB[7]) co-assembled ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2020, 56(62):8857-8860]

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Electronic engineering of CoSe/FeSe2 hollow nanospheres for efficient water oxidation.

Yi Zhang, Jie Xu, Lin Lv, Aiwu Wang, Baoshun Zhang, Yigang Ding, Chundong Wang,

First-row non-precious metal-based catalysts are widely studied and recognized as potential substitutes for precious metal-based catalysts in the oxygen evolution reaction (OER) for hydrogen generation but their application remains challenging. In this study, a unique class of Co-Fe selenide hollow nanospheres ([email protected]) is well-designed through a facile hydrothermal method. The ... Read more >>

Nanoscale (Nanoscale)
[2020, 12(18):10196-10204]

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Abnormal Upregulation of Cardiovascular Disease Biomarker PLA2G7 Induced by Proinflammatory Macrophages in COVID-19 patients

Yang LI, Yongzhong JIANG, Yi ZHANG, Naizhe LI, Qiangling YIN, Linlin LIU, Xin LV, Yan LIU, Aqian LI, Bin FANG, Jiajia LI, Hengping YE, Gang YANG, Xiaoxian CUI, Yang LIU, Yuanyuan QU, Chuan LI, Jiandong LI, Dexin LI, Shiwen WANG, Zhongtao GAI, Faxian ZHAN, Mifang LIANG,

BACKGROUND. Coronavirus disease 2019 (COVID-19) triggers distinct patterns of pneumonia progression with multiorgan disease, calling for cell- and/or tissue-type specific host injury markers. METHODS. An integrated hypothesis-free single biomarker analysis framework was performed on nasal swabs (n=484) from patients with COVID-19 in GSE152075. The origin of candidate biomarker was assessed ... Read more >>

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Zero-dimensional hybrid iodobismuthate derivatives: from structure study to photovoltaic application.

Yi Zhang, Farzaneh Fadaei Tirani, Philip Pattison, Kurt Schenk-Joß, Zewen Xiao, Mohammad Khaja Nazeeruddin, Peng Gao,

The quest for lead-free light-absorbing perovskite materials has long been the target of researchers to make the 'star' material friendly to the commercial market. After a summary of different lead-free solar absorbers, we demonstrate a zero-dimensional iodobismuthate (MA)3[BiI6]·3MACl (MA: CH3NH3) featuring isolated hexaiodobismuthate(iii) anions in the crystal analysis. The unexpectedly ... Read more >>

Dalton Trans (Dalton transactions (Cambridge, England : 2003))
[2020, 49(18):5815-5822]

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A high voltage aqueous zinc-manganese battery using a hybrid alkaline-mild electrolyte.

Weijia Fan, Fei Liu, Yu Liu, Zhixian Wu, Lili Wang, Yi Zhang, Qinghong Huang, Lijun Fu, Yuping Wu,

A high-voltage aqueous zinc-manganese battery using an alkaline-mild hybrid electrolyte is reported. The operation voltage of the battery can reach 2.2 V. The energy density is 487 W h kg-1 at 200 mA g-1, calculated based on the positive electrode material, higher than that of a Zn-MnO2 battery in mild ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2020, 56(13):2039-2042]

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Preparation of Galactosyl Nanoparticles and Their Targeting Efficiency to Hepatocellular Carcinoma.

Wei Liao, Yan Tang, Zhengcui Hu, Chunyan Wang, Yi Chen, Yi Zhang, Wenhan Fan, Bernd Klaubert, Jeremy D Hoisak,

Liver diseases seriously endanger people's physical health, especially liver cancer, and its morbidity and mortality have increased year by year. The reason why liver cancer is difficult to cure is that in addition to the low lethality of cancer drugs to cancer cells, another important factor is that the drugs ... Read more >>

J Nanosci Nanotechnol (Journal of nanoscience and nanotechnology)
[2021, 21(2):987-994]

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cis alkenes stabilized by intramolecular sulphurπ interactions.

Xiaolei Zhao, Wei Zheng, Yi Zhang, Wei Huang,

A series of alkenes with bistable isomers were obtained containing a thiophene/azoheteroaryl backbone. Visible light and heat-induced reversible cis ⇌ trans isomerizations were evidenced by UV-Vis and 1H NMR spectra. The stabilization of cis alkenes was attributed to intramolecular sulphurπ (Sπ) interactions, which were further supported by theoretical calculations. ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2020, 56(5):814-817]

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Carbon nanotube-encapsulated cobalt for oxygen reduction: integration of space confinement and N-doping.

Qichen Wang, Ke Ye, Liang Xu, Wei Hu, Yongpeng Lei, Yi Zhang, Yin Chen, Kechao Zhou, Jun Jiang, Jean M Basset, Dingsheng Wang, Yadong Li,

We report carbon nanotube-encapsulated cobalt as an efficient oxygen reduction electrocatalyst (onset potential of 0.94 V and half-potential of 0.84 V). Calculation results firstly reveal that Co protected by graphitic-N-doped carbon holds more negative charge (-1.22 eV) and has an energy barrier (0.56 eV) lower than that of pyridinic-N-doped carbon ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2019, 55(98):14801-14804]

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Brain-derived neurotrophic factor protects against acrylamide-induced neuronal and synaptic injury via the TrkB-MAPK-Erk1/2 pathway.

Xiao Chen, Jing-Wei Xiao, Peng Cao, Yi Zhang, Wen-Jian Cai, Jia-Yang Song, Wei-Min Gao, Bin Li,

Acrylamide has been shown to be neurotoxic. Brain-derived neurotrophic factor (BDNF) can alleviate acrylamide-induced synaptic injury; however, the underlying mechanism remains unclear. In this study, dibutyryl-cyclic adenosine monophosphate-induced mature human neuroblastoma (NB-1) cells were exposed with 0-100 μg/mL acrylamide for 24-72 hours. Acrylamide decreased cell viability and destroyed synapses. Exposure ... Read more >>

Neural Regen Res (Neural regeneration research)
[2021, 16(1):150-157]

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A sandwich-like Si/SiC/nanographite sheet as a high performance anode for lithium-ion batteries.

Yi Zhang, Kai Hu, Jinghui Ren, Yuping Wu, Nengfei Yu, Ailing Feng, Zhengyong Huang, Zirui Jia, Guanglei Wu,

Silicon/carbon (Si/C) nanocomposite anodes have attracted great interest for their use in lithium-ion batteries (LIBs). However, Si nanoparticles are difficult to stabilize on a carbon surface. Herein, we solve this stabilization problem by designing a Si/silicon carbide/nanographite sheet (Si/SiC/NanoG) nanocomposite. The Si/SiC/NanoG nanocomposite is synthesized by the magnesium thermal reduction ... Read more >>

Dalton Trans (Dalton transactions (Cambridge, England : 2003))
[2019, 48(47):17683-17690]

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Genetic determination of processing traits in the red swamp crayfish, Procambarus clarkii (Girard)

Wang Hui, Shi Wenjing, Wang Long, Zhang Yi, Zang Nengwei, Xue Chaopeng, Chang Guoliang, Wu Nan,

The additive genetic correlations of processing traits (two traits, abdominal meat weight and yield) with growth (body weight) and morphometrics (seven traits, chela length, chela width, cephalothorax length, cephalothorax width, abdominal length, abdominal width and abdominal depth) in red swamp crayfish (6 months old) were first estimated within two sexes based ... Read more >>

Aquaculture (Aquaculture (Amsterdam, Netherlands))
[2020, 529:Not Available]

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A Smart Chest Pain Center to Improve Quality Control and Reduce Doctor's Workload of Acute Myocardial Infarction.

Yifan Zhao, Sixiao Ding, Wenhui Peng, Yi Zhang, Yawei Xu,

The establishment of a chest pain center (CPC) is an important strategy to improve the treatment of urgent cardiovascular disease, especially acute myocardial infarction. In order to monitor and continuously improve the quality of diagnosis and treatment of CPCs, accurate records of key time points must be made in the ... Read more >>

Crit Pathw Cardiol (Critical pathways in cardiology)
[2020, 19(4):161-165]

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Opioid Use in Adults With Low Back or Lower Extremity Pain Who Undergo Spine Surgical Treatment Within 1 Year of Diagnosis.

Parastou Fatemi, Yi Zhang, Allen Ho, Roberto Lama, Michael Jin, Anand Veeravagu, Atman Desai, John K Ratliff,

STUDY DESIGN:Retrospective longitudinal cohort. OBJECTIVE:We investigated opioid prescribing patterns amongst adults in the United States diagnosed with low back or lower extremity pain (LBP/LEP) who underwent spine surgery. SUMMARY OF BACKGROUND DATA:Opioid-based treatment of LBP/LEP and postsurgical pain has separately been associated with chronic opioid use, but a combined and ... Read more >>

Spine (Phila Pa 1976) (Spine)
[2020, 45(24):1725-1735]

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Ectopic pituitary adenomas: clinical features, diagnostic challenges and management.

Jianyu Zhu, Zhicheng Wang, Yi Zhang, Xiaoxu Li, Jie Liu, Kan Deng, Lin Lu, Hui Pan, Renzhi Wang, Yong Yao, Huijuan Zhu,

PURPOSE:Ectopic pituitary adenomas (EPAs) are extremely rare pituitary adenomas located outside the sella turcica without any connection with intrasellar components. This study aims to review all the reported cases to date and describe the clinical characteristics of EPAs. METHODS:In a retrospective chart review, 14 patients were identified with EPAs in ... Read more >>

Pituitary (Pituitary)
[2020, 23(6):648-664]

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FAM136A immunoreactivity is associated with nodal involvement and survival in lung adenocarcinoma in a Chinese case series.

Liufang Zhao, Chunlei Ge, Zhiwei Zhang, Hongyan Hu, Yi Zhang, Wentao Zhao, Ruilei Li, Baozhen Zeng, Xin Song, Gaofeng Li,

Lung cancer patients with lymph node metastasis usually had short overall survival and occurred distant metastases at the early stage. However, some of these people did have more prolonged survival. The underlying reason is still unclear. In this study, we found a novel molecule, family with sequence similarity 136, member ... Read more >>

Bioengineered (Bioengineered)
[2020, 11(1):261-271]

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MXene-based ultra-thin film for terahertz radiation shielding.

Qi Zou, Wenyu Guo, Long Zhang, Liting Yang, Zhenyu Zhao, Feng Liu, Xiang Ye, Yi Zhang, Wangzhou Shi,

We have successfully fabricated Ti-based MXenes flakes, Ti3C2Tx, by chemical etching, then prepared it as an organic dispersion and finally spin-coated it on polyimide plastic substrate for terahertz wave shielding. The shielding effectivity of the 12 μm ultra-thin film can reach up to 17 dB measured by the terahertz time-domain ... Read more >>

Nanotechnology (Nanotechnology)
[2020, 31(50):505710]

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Risks and features of secondary infections in severe and critical ill COVID-19 patients.

Haocheng Zhang, Yi Zhang, Jing Wu, Yang Li, Xian Zhou, Xin Li, Haili Chen, Mingquan Guo, Shu Chen, Feng Sun, Richeng Mao, Chao Qiu, Zhaoqin Zhu, Jingwen Ai, Wenhong Zhang,

Objectives Severe or critical COVID-19 is associated with intensive care unit admission, increased secondary infection rate, and would lead to significant worsened prognosis. Risks and characteristics relating to secondary infections in severe COVID-19 have not been described. Methods Severe and critical COVID-19 patients from Shanghai were included. We collected lower ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2020, 9(1):1958-1964]

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Topological changes in white matter connectivity network in patients with Parkinson's disease and depression.

Xiao Hu, Long Qian, Yaoyu Zhang, Yuanyuan Xu, Li Zheng, Yijun Liu, Xiangrong Zhang, Yi Zhang, Weiguo Liu,

Depression is the most common non-motor symptom accompanying Parkinson's disease (PD) with high prevalence but unclear pathophysiological mechanism. Relatively little is known about the topological patterns of white matter structural networks in depressed patients with PD. In this study, we used diffusion-tensor imaging (DTI) and graph theory approaches to explore ... Read more >>

Brain Imaging Behav (Brain imaging and behavior)
[2020, 14(6):2559-2568]

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Beneficial Effects of Weekly Walking Activity on Vascular Hypertensive Mediated Organ Damage in Community-dwelling Elderly Chinese: Northern Shanghai Study

Yuyan Lyu, Shikai Yu, Chen Chi, Jiadela Teliewubai, Hongwei Ji, Yi Zhang, Yawei Xu,

Abstract Background: The value of exercise is well-established for health promotion. Walking as the most common campaign in older people, is recommended to improve their cardiovascular health. However, the direct association between weekly walking activity and asymptomatic hypertensive mediated organ damage (HMOD) remains unclear.Methods: 2830 community-dwelling elderly subjects (over 65 ... Read more >>

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Effect of Circhipk3 on Polarization of Microglial Cells in Nerve Injury Caused by Heat Radiation

Wang Lei, Shen Yiming, Zhu Baofeng, Qian Chen, Zhang Yi,

Abstract Background: Circular RNAs play an important regulatory role in the occurrence and development of nerve damage and related diseases, but there is little research on non-coding RNAs in heat sickness, especially circRNAs, and there has been no report on the mechanism of fever progression. Methods: 1. Mice were randomly ... Read more >>

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Association between organ damage and visceral adiposity index in community-dwelling elderly Chinese population: the Northern Shanghai Study.

Chong Xu, Song Zhao, Shikai Yu, Chen Chi, Ximin Fan, Hongwei Ji, Rusitanmujiang Maimaitiaili, Jiadela Teliewubai, Xiaofeng Li, Yi Zhang, Yawei Xu,

BACKGROUND:The visceral adiposity index (VAI) is a newly developing indicator about visceral fat function and insulin resistance. This research aims to assess the association between organ damage and VAI in the community-dwelling elderly Chinese population. METHODS:In total, 3363 elderly participants were recruited between June 2014 and August 2019. VAI was ... Read more >>

Aging Clin Exp Res (Aging clinical and experimental research)
[2020, :]

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Inflammatory Biomarkers in induced Sputum Predict Chronic Obstructive Pulmonary Disease (COPD) Severity

Yuting He, Zhi Deng, Jianjun Jin, Ruolin Mao, Lei Gao, Yi Zhang, Gang Wang, Peng Gao, Min Xie, Huayin Li, Zhihong Chen,

Abstract Background: The progression of an abnormal inflammatory response plays a crucial role in the functional decline that occurs in COPD patients[1].Compared to serum biomarkers, inflammatory biomarkers in induced sputum would be a more reliable reflection of the inflammatory processes in the airways. Based on this, we explored the association ... Read more >>

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