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Enhanced energy-storage performance of an all-inorganic flexible bilayer-like antiferroelectric thin film via using electric field engineering.

Bingzhong Shen, Yong Li, Ningning Sun, Ye Zhao, Xihong Hao,

A novel all-inorganic flexible bilayer-like Pb0.99Nb0.02(Zr0.55Sn0.40Ti0.05)0.98O3 (PNZSTBL) thin film with the same chemical composition is designed to enhance its energy-storage performance. The PNZSTBL thin film that consists of a large polarization (PNZSTLP) top layer and a high electric breakdown field (PNZSTHE) bottom layer are deposited on flexible mica by controlling ... Read more >>

Nanoscale (Nanoscale)
[2020, 12(16):8958-8968]

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The Runx1/Notch1 Signaling Pathway Participates in M1/M2 Microglia Polarization in a Mouse Model of Temporal Lobe Epilepsy and in BV-2 Cells.

Xian-Lian Deng, Li Feng, Zi-Xin Wang, Yue-E Zhao, Qiong Zhan, Xiao-Mei Wu, Bo Xiao, Yi Shu,

Microglial activation and phenotypic shift play vital roles in many neurological diseases. Runt-related transcription factor-1 (Runx1), which is localized on microglia, inhibits amoeboid microglial proliferation. Preliminary data have indicated that the interaction of Runx1 with the Notch1 pathway affects the hemogenic endothelial cell shift. However, little is known about the ... Read more >>

Neurochem. Res. (Neurochemical research)
[2020, :]

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Correction to: The Protective Effects of Butorphanol on Pulmonary Function of Patients with Obesity Undergoing Laparoscopic Bariatric Surgery: A Double-Blind Randomized Controlled Trial.

Xiu-Li Wang, Si Zeng, Xiao-Xiao Li, Ye Zhao, Xing-He Wang, Tong Li, Su Liu,

In the original article some of the references were ordered incorrectly. ... Read more >>

Obes Surg (Obesity surgery)
[2020, :]

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The Protective Effects of Butorphanol on Pulmonary Function of Patients with Obesity Undergoing Laparoscopic Bariatric Surgery: a Double-Blind Randomized Controlled Trial.

Xiu-Li Wang, Si Zeng, Xiao-Xiao Li, Ye Zhao, Xing-He Wang, Tong Li, Su Liu,

BACKGROUND:Obesity is a risk factor for postoperative pulmonary complications (PPCs). Recent studies have reported the pulmonary protective role of the kappa opioid receptor (KOR). Butorphanol is a narcotic with strong KOR agonist action, and the role in pulmonary protection is uncertain. Here, we hypothesized that butorphanol exerts protective effects on ... Read more >>

Obes Surg (Obesity surgery)
[2020, :]

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Downexpression of HSD17B6 correlates with clinical prognosis and tumor immune infiltrates in hepatocellular carcinoma.

Lei Lv, Yujia Zhao, Qinqin Wei, Ye Zhao, Qiyi Yi,

Background:Hydroxysteroid 17-Beta Dehydrogenase 6 (HSD17B6), a key protein involved in synthetizing dihydrotestosterone, is abundant in the liver. Previous studies have suggested a role for dihydrotestosterone in modulating progress of various malignancies, and HSD17B6 dysfunction was associated with lung cancer and prostate cancer. However, little is known about the detailed role ... Read more >>

Cancer Cell Int. (Cancer Cell International)
[2020, 20:210]

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Three-Dimensional Assessments of Intraocular Lens Stability With High-Speed Swept-Source Optical Coherence Tomography.

Xixia Ding, Qinmei Wang, Linfeng Xiang, Pingjun Chang, Shenghai Huang, Yun-E Zhao,

PURPOSE:To evaluate the effect of intraocular lens (IOL) optic overlapping on IOL stability and to determine the relationship between the capsulorhexis and IOL movement with the three-dimensional method of swept-source optical coherence tomography (SS-OCT). METHODS:This study identified patients with age-related cataracts and divided them into two groups according to their ... Read more >>

J Refract Surg (Journal of refractive surgery (Thorofare, N.J. : 1995))
[2020, 36(6):388-394]

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A case of unplanned pregnancy at 2 months after uterine curettage in a patient with a hydatidiform mole.

Jie-Qiong Cao, Ye Zhao, Ying Ma, Qiu-Man Wang, Li-Na Niu, Si Qiao,

Whether an unplanned pregnancy should be terminated during follow-up of a hydatidiform mole is controversial. We report a patient who had an unplanned pregnancy with a hydatidiform mole at 2 months after uterine curettage when the human chorionic gonadotropin level had decreased to a negative value. Hydatidiform mole was confirmed ... Read more >>

J. Int. Med. Res. (The Journal of international medical research)
[2020, 48(6):300060520925961]

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PPARγ as an E3 Ubiquitin-Ligase Impedes Phosphate-Stat6 Stability and Promotes Prostaglandins E2-Mediated Inhibition of IgE Production in Asthma.

Jia Wu, Yan Wang, Yu Zhou, Yuqing Wang, Xiaowan Sun, Ye Zhao, Youfei Guan, Yu Zhang, Wei Wang,

Increased serum IgE level is one of the features of allergic asthma. It is reported that IgE production can be enhanced by E-prostanoid 2 (EP2) receptor of prostaglandin E2 (PGE2); however, whether E-prostanoid 4 (EP4) receptor (encoded by Ptger4) has a unique or redundant role is still unclear. Here, we ... Read more >>

Front Immunol (Frontiers in Immunology)
[2020, 11:]

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Fecal Microbiota Transplantation for Grade IV Steroid Refractory GI-GvHD: Interim Results a Non-randomized, Open-label, Phase 1 Clinical Study

Ye Zhao, Xue-wei Li, Yu-jing Zhou, Xiao Ma, Feng Chen, Xiao-hui Hu, Song Jin, Xue-feng He, Jin Gao, Bao-li Zhu, De-pei Wu, xiaofei qi,

Abstract BackgroundGastrointestinal (GI) tract graft- vs -host disease (GvHD) is a major cause of post-allo-HCT morbidity and mortality. Patients with steroid-refractory GI-GvHD face a poor prognosis and limited therapeutic options. Here, we report an interim analysis on the safety and efficacy of fecal microbiota transplantation (FMT) in treating steroid-refractory GI-GvHD.MethodsWe ... Read more >>

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Efficacy and Safety of Tongning Gel for Knee Osteoarthritis: A Multicentre, Randomized, Double-Blinded, Parallel, Placebo-Controlled, Clinical Trial.

Ye Zhao, Zhi Bi Shen, Ji Rong Ge, Wen Gang Liu, Jun Xing Yang, Cheng Jian He, Min Lu, Lin Shen, Hong Yin, Yong Qiang Chen, Zhi Bin Li, Qing Sun, Li Ming Xie, Wei An Yuan, Yu Xin Zheng, Hong Sheng Zhan,

Objective:To evaluate the efficacy and safety of Tongning Gel (TNG) compared to placebo-controlled (PC) for knee osteoarthritis (KOA). Methods:A multicentre, randomized, double-blinded, parallel, placebo-controlled, clinical trial was performed in 576 patients (432 patients in the TNG group, 144 patients in the PC group), and 1 in the experimental group withdrew ... Read more >>

Evid Based Complement Alternat Med (Evidence-based complementary and alternative medicine : eCAM)
[2020, 2020:8707256]

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1,25(OH)2D3 mitigate cancer-related fatigue in tumor-bearing mice: Integrating network pharmacological analysis.

Yue-Tao Zhou, Shuang-Shuang Li, Min Ai, Hong Chen, Yi-Xiao Liu, Bo-Yan Li, Ye Zhao, Wei-Wei Cai, Bao Hou, Lu-Lu Ni, Fei Xu, Li-Ying Qiu,

Cancer-related fatigue (CRF) is one of the most common and serious complications in cancer patients, which greatly reduces the quality of life. The mechanism induced fatigue may be diverse. In this study, we tried to investigate the effect of 1,25(OH)2D3, the active metabolite of vitamin D on CRF in Lewis ... Read more >>

Biomed. Pharmacother. (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie)
[2020, 128:110256]

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Phenotype Spectrum reflects Synergies among the Cell Architecture over Stages of the Cell Cycle

Tian Lan, Meng Yu, Weisheng Chen, Jun Yin, Hsiang-Tsun Chang, Shan Tang, Ye Zhao, Spyros Svoronos, Samuel Wong, Yiider Tseng,

Abstract The heterogeneity of cell phenotypes remains a barrier in progressing cell research and a challenge in conquering cancer-related drug resistance. Cell morphology, the most direct property of cell phenotype, evolves along the progression of the cell cycle; meanwhile, cell motility, the dynamic property of cell phenotype, also alters over ... Read more >>

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CDK5 Activates Hippo Signaling to Confer Resistance to Radiation Therapy Via Upregulating TAZ in Lung Cancer.

Yulan Zeng, Quan Liu, Ye Wang, Chen Tian, Qifan Yang, Ye Zhao, Li Liu, Gang Wu, Shuangbing Xu,

PURPOSE:Tumor resistance to radiation therapy is a therapeutic challenge in the treatment of patients with non-small cell lung cancer. Cyclin-dependent kinase 5 (CDK5) has been proposed to participate in cell proliferation, migration and invasion, drug resistance, and immune evasion. However, the functions and regulatory mechanisms of CDK5 in lung cancer ... Read more >>

Int. J. Radiat. Oncol. Biol. Phys. (International journal of radiation oncology, biology, physics)
[2020, :]

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Gender-differentiated metabolic abnormalities of adult zebrafish with zinc pyrithione (ZPT) -induced hepatotoxicity.

Ye Zhao, Fanrong Meng, Cunbao Ding, Yang Yu, Guisen Zhang, Chimeng Tzeng,

Zinc pyrithione (ZPT) is an extensively used microbicidal agent and its toxicity to multiple organs has been gradually recognized. However, details of the mechanism of ZPT toxicity are lacking and profile studies at metabolic level are still greatly limited. In this work we investigated the effects of ZPT on metabolic ... Read more >>

Chemosphere (Chemosphere)
[2020, 257:127177]

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Coordination induced electron redistribution to achieve highly reversible Li-ion insertion chemistry in metal-organic frameworks.

Zhao Ye, Yaojun Liu, Chun Fang, Wange Chen, Mingyang Ou, Long Li, Xing Lin, Zhixiang Rao, Yaqi Liao, Ruirui Zhao, Weilun Chen, Yunhui Huang,

Herein, the coordination-induced increase in the electron density of fused C6 rings in MOFs as high performance anode materials for Li+ ion batteries is described. Zn-PTCA is able to deliver a high specific capacity of 700 mA h g-1 at 50 mA g-1 and exhibits excellent cycle performance over 1100 ... Read more >>

Chem. Commun. (Camb.) (Chemical communications (Cambridge, England))
[2020, 56(47):6424-6427]

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Association between Serum Vitamin C and the Blood Pressure: A Systematic Review and Meta-Analysis of Observational Studies.

Li Ran, Wenli Zhao, Xiaodong Tan, Hongwu Wang, Kaito Mizuno, Ken Takagi, Ye Zhao, Huaien Bu,

Background:Hypertension is regarded as a major and independent risk factor of cardiovascular diseases, and numerous studies observed an inverse correlation between vitamin C intake and blood pressure. Aim:Our aim is to investigate the relationship between serum vitamin C and blood pressure, including the concentration differences and the correlation strength. Method:Two ... Read more >>

Cardiovasc Ther (Cardiovascular therapeutics)
[2020, 2020:4940673]

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Surgical Outcomes and Predictors of Visual Function Alterations After Transcranial Surgery for Large-to-Giant Pituitary Adenomas.

Ming Shen, Zhengyuan Chen, Xuefei Shou, Zengyi Ma, Zhao Ye, Wenqiang He, Yichao Zhang, Nidan Qiao, Qilin Zhang, Yue Shen, Keyi Zhang, Xiang Zhou, Xiaoyun Cao, Yao Zhao, Shiqi Li, Yongfei Wang,

BACKGROUND:Factors associated with visual outcomes after transcranial surgery for large-to-giant pituitary adenomas have not been fully elucidated. METHODS:We recruited 37 patients with large-to-giant pituitary adenomas between January 2014 and December 2016 and assessed their tumor characteristics and surgical outcomes. Visual acuity and visual field were evaluated by visual impairment score ... Read more >>

World Neurosurg (World neurosurgery)
[2020, :]

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Longitudinal changes of macular structure after lens removal combined with anterior vitrectomy after pediatric cataract surgery.

Dandan Wang, Tong Tian, Jiajun Wang, Zhangliang Li, Pingjun Chang, Xixia Ding, Yinying Zhao, Yun-E Zhao,

PURPOSE:To explore the macular thickness changes after lens removal combined with anterior vitrectomy for pediatric cataract surgery. SETTING:The Eye Hospital of Wenzhou Medical University, Zhejiang, China. DESIGN:Prospective study. METHODS:Thirty children (40 eyes) aged between 3 and 9 years with pediatric cataracts, including 20 children (20 eyes) with unilateral cataracts and ... Read more >>

J Cataract Refract Surg (Journal of cataract and refractive surgery)
[2020, :]

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[A comparative study on the surface electromyography of lumbosacral multifidus muscle in patients with lumbar disc herniation].

Ye Zhao, Ling-San Hu, Cheng-Zhe Zhang, Min Zhang, Hong-Sheng Zhan, Wei-An Yuan,

OBJECTIVE:To compare the degeneration of lumbosacral multifidus muscle in patients with lumbar disc herniation. METHODS:Thirty-five healthy volunteers and 35 patients with unilateral L4,5 lumbar disc herniation from December 2015 to September 2017 were recruited. There were 20 males and 15 females in each group, aged from 25 to 55 years ... Read more >>

Zhongguo Gu Shang (Zhongguo gu shang = China journal of orthopaedics and traumatology)
[2020, 33(5):449-453]

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A chemiluminescence immunoassay for rapid detection of classical swine fever virus E2 antibodies in pig serum samples.

Zhongyuan Ma, Jianliang Lv, Zhongwang Zhang, Ye Zhao, Li Pan, Yongguang Zhang,

The high performance of chemiluminescence immunoassays (CLIAs) in diagnosis has been gradually recognized in recent years, but their application in the diagnosis of classical swine fever (CSF) has not been reported. Here, a recombinant E2 (rE2) protein and a peroxidase-conjugated monoclonal antibody (MAb G5) were used to develop a competition-based ... Read more >>

Transbound Emerg Dis (Transboundary and emerging diseases)
[2020, :]

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The Evolution of Publication Hotspots in Electronic Health Records from 1957 to 2016 and Differences Among Six Countries.

Yanjun Wang, Ye Zhao, Weijia Dang, Jianzhong Zheng, Haiyuan Dong,

This study aims to reveal the evolution of publication hotspots in the field of electronic health records (EHRs) and differences among countries. We applied keyword frequency analysis, keyword co-occurrence analysis, principal component analysis, multidimensional scaling analysis, and visualization technology to compare the high-frequency Medical Subject Heading (MeSH) terms in six ... Read more >>

Big Data (Big data)
[2020, 8(2):89-106]

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Effect of dietary L-glutamate levels on growth, digestive and absorptive capability, and intestinal physical barrier function in Jian carp (Cyprinus carpio var. Jian).

Ye Zhao, Tian-Ran Zhang, Qian Li, Lin Feng, Yang Liu, Wei-Dan Jiang, Pei Wu, Juan Zhao, Xiao-Qiu Zhou, Jun Jiang,

The present study explored effects of L-glutamate (Glu) levels on growth, digestive and absorptive capability, and intestinal physical barrier functions of Jian carp (Cyprinus carpio). A total of 600 Jian carp (126.40 ± 0.21 g) were randomly distributed into 5 groups with 3 replicates each, fed diets containing graded levels of Glu (53.4 ... Read more >>

Anim Nutr (Animal nutrition (Zhongguo xu mu shou yi xue hui))
[2020, 6(2):198-209]

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BRD4 as a therapeutic target for nonfunctioning and growth hormone pituitary adenoma.

Chengzhang Shi, Zhao Ye, Jie Han, Xiaoqing Ye, Wenchao Lu, Chenxing Ji, Zizhou Li, Zengyi Ma, Qilin Zhang, Yichao Zhang, Wenqiang He, Zhengyuan Chen, Xiaoyun Cao, Xuefei Shou, Xiang Zhou, Yongfei Wang, Zhaoyun Zhang, Yiming Li, Hongying Ye, Min He, Hong Chen, Haixia Cheng, Jun Sun, Jianyong Cai, Chuanxin Huang, Fei Ye, Cheng Luo, Bing Zhou, Hong Ding, Yao Zhao,

Nonfunctioning pituitary adenoma (NFPA) and growth hormone pituitary adenoma (GHPA) are major subtypes of pituitary adenomas (PAs). The primary treatment is surgical resection. However, radical excision remains challenging, and few effective medical therapies are available. It is urgent to find novel targets for the treatment. Bromodomain-containing protein 4 (BRD4) is ... Read more >>

Neuro-oncology (Neuro-oncology)
[2020, :]

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Comparison of two intense pulsed light patterns for treating patients with meibomian gland dysfunction.

Yue Wu, Junhua Li, Man Hu, Yinying Zhao, Xiaolei Lin, Yiqin Chen, Lu Li, Yun-E Zhao,

PURPOSE:The objective of this was to determine the efficacy of different patterns of intense pulsed light (IPL) therapy in patients with meibomian gland dysfunction (MGD). MATERIALS AND METHOD:IPL treatment was administered in 124 eyes of 62 patients with MGD-associated dry eye disease (DED). These patients were divided randomly into two ... Read more >>

Int Ophthalmol (International ophthalmology)
[2020, 40(7):1695-1705]

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Clinical Characteristics and Surgical Safety in Congenital Cataract Eyes with Three Pathological Types of Posterior Capsule Abnormalities.

Xixia Ding, Linfeng Xiang, Qianwei Wang, Dandan Wang, Pingjun Chang, Zhangliang Li, Yinying Zhao, Feixue Chu, Chao Ma, Yun-E Zhao,

Purpose:To observe the clinical characteristics of 3 pathological types of posterior capsule abnormalities (PCAs) in congenital cataracts (CCs) and evaluate the surgical safety in these eyes. Methods:This study involved 239 children (367 eyes) with CC who underwent cataract surgery at the Eye Hospital of Wenzhou Medical University. All surgery videos ... Read more >>

J Ophthalmol (Journal of ophthalmology)
[2020, 2020:6958051]

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