Full Text Journal Articles by
Author Yaseen M Arabi

Advertisement

Find full text journal articles






Validation and utility of ARDS subphenotypes identified by machine-learning models using clinical data: an observational, multicohort, retrospective analysis.

Manoj V Maddali, Matthew Churpek, Tai Pham, Emanuele Rezoagli, Hanjing Zhuo, Wendi Zhao, June He, Kevin L Delucchi, Chunxue Wang, Nancy Wickersham, J Brennan McNeil, Alejandra Jauregui, Serena Ke, Kathryn Vessel, Antonio Gomez, Carolyn M Hendrickson, Kirsten N Kangelaris, Aartik Sarma, Aleksandra Leligdowicz, Kathleen D Liu, Michael A Matthay, Lorraine B Ware, John G Laffey, Giacomo Bellani, Carolyn S Calfee, Pratik Sinha, ,

<h4>Background</h4>Two acute respiratory distress syndrome (ARDS) subphenotypes (hyperinflammatory and hypoinflammatory) with distinct clinical and biological features and differential treatment responses have been identified using latent class analysis (LCA) in seven individual cohorts. To facilitate bedside identification of subphenotypes, clinical classifier models using readily available clinical variables have been described in ... Read more >>

Lancet Respir Med (The Lancet. Respiratory medicine)
[2022, :]

Cited: 0 times

View full text PDF listing >>



Nutrition priorities in obese critically ill patients.

Hasan M Al-Dorzi, Renee Stapleton, Yaseen M Arabi,

<h4>Purpose of review</h4>During critical illness, several neuroendocrine, inflammatory, immune, adipokine, and gastrointestinal tract hormone pathways are activated; some of which are more intensified among obese compared with nonobese patients. Nutrition support may mitigate some of these effects. Nutrition priorities in obese critically ill patients include screening for nutritional risk, estimation ... Read more >>

Curr Opin Clin Nutr Metab Care (Current opinion in clinical nutrition and metabolic care)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Advertisement

Association of KIR gene polymorphisms with COVID-19 disease.

Ali Hajeer, Dunia Jawdat, Salam Massadeh, Nora Aljawini, Malak S Abedalthagafi, Yaseen M Arabi, Manal Alaamery,

<h4>Background</h4>Natural killer (NK) cells play an essential role against viruses. NK cells express killer cell immunoglobulin-like receptors (KIRs) which regulate their activity and function. The polymorphisms in KIR haplotypes confer differential viral susceptibility and disease severity caused by infections. We investigated the association between KIR genes and COVID-19 disease severity.<h4>Methods</h4>424 ... Read more >>

Clin Immunol (Clinical immunology (Orlando, Fla.))
[2022, 234:108911]

Cited: 0 times

View full text PDF listing >>



A guide to enteral nutrition in intensive care units: 10 expert tips for the daily practice.

Jean-Charles Preiser, Yaseen M Arabi, Mette M Berger, Michael Casaer, Stephen McClave, Juan C Montejo-González, Sandra Peake, Annika Reintam Blaser, Greet Van den Berghe, Arthur van Zanten, Jan Wernerman, Paul Wischmeyer,

The preferential use of the oral/enteral route in critically ill patients over gut rest is uniformly recommended and applied. This article provides practical guidance on enteral nutrition in compliance with recent American and European guidelines. Low-dose enteral nutrition can be safely started within 48 h after admission, even during treatment with ... Read more >>

Crit Care (Critical care (London, England))
[2021, 25(1):424]

Cited: 0 times

View full text PDF listing >>



Management of acute atrial fibrillation in the intensive care unit: an international survey.

Mik Wetterslev, Morten Hylander Møller, Anders Granholm, Christian Hassager, Nicolai Haase, Tayyba Naz Aslam, Jiawei Shen, Paul J Young, Anders Aneman, Johanna Hästbacka, Martin Siegemund, Maria Cronhjort, Elin Lindqvist, Sheila N Myatra, Kushal Kalvit, Yaseen M Arabi, Wojciech Szczeklik, Martin I Sigurdsson, Martin Balik, Frederik Keus, Anders Perner, ,

<h4>Background</h4>Atrial fibrillation (AF) is common in intensive care unit (ICU) patients and associated with poor outcomes. Different management strategies exist, but the evidence is limited and derived from non-ICU patients. This international survey of ICU doctors evaluated the preferred management of acute AF in ICU patients.<h4>Method</h4>We conducted an international online ... Read more >>

Acta Anaesthesiol Scand (Acta anaesthesiologica Scandinavica)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Sepsis in end-stage renal disease patients: are they at an increased risk of mortality?

Ralphe Bou Chebl, Hani Tamim, Gilbert Abou Dagher, Musharaf Sadat, Ghassan Ghamdi, Abdulrahman Itani, Alawi Saeedi, Yaseen M Arabi,

<h4>Objectives</h4>This study aims to examine the outcome of end-stage renal disease (ESRD) patients admitted with sepsis to the intensive care unit (ICU).<h4>Design</h4>Single centre, retrospective cohort study.<h4>Setting</h4>The study was conducted in the Intensive Care Department of King Abdulaziz Medical City, Riyadh, Saudi Arabia.<h4>Participants</h4>Data were extracted from a prospectively collected ICU database ... Read more >>

Ann Med (Annals of medicine)
[2021, 53(1):1737-1743]

Cited: 1 time

View full text PDF listing >>



Outcomes of cirrhotic patients admitted to the intensive care unit after a successful cardiac arrest resuscitation.

Moayed N Alkhlewi, Hasan M Al-Dorzi, Farhan Z Alenezi, Abdulrahman M Farhat, Hani Tamim, Musharaf Sadat, Felwa Bin Humaid, Yaseen M Arabi,

<h4>Objectives</h4>To evaluate the outcomes of cirrhotic patients admitted to the intensive care unit (ICU) following cardiac arrest.<h4>Methods</h4>This was a single centre retrospective study of all the cirrhotic patients, admitted to the ICU at King Abdulaziz Medical City, Riyadh, Saudi Arabia, after a successful cardiac arrest resuscitation, from 1999 to 2017. ... Read more >>

Saudi Med J (Saudi medical journal)
[2021, 42(12):1320-1324]

Cited: 0 times

View full text PDF listing >>



Kinetics of antibody response in critically ill patients with Middle East respiratory syndrome and association with mortality and viral clearance.

Yaseen M Arabi, Ali H Hajeer, Hanan Balkhy, Sameera Al Johani, Musharaf Sadat, Abdulaziz Al-Dawood, Alanoud Abu Taleb, Jesna Jose, Eman Al Qasim, Abdulaziz Al Ajlan,

The objective of this study is to examine the IgG antibody response in critically ill patients with the Middle East respiratory syndrome (MERS) and to examine the association of early antibody response with mortality and viral clearance. We collected blood samples from 40 consecutive real-time reverse transcription-polymerase chain reaction (rRT-PCR) ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):22548]

Cited: 0 times

View full text PDF listing >>



Statistical analysis plan for the Steppedwedge Cluster Randomized trial of Electronic Early Notification of sepsis in hospitalized ward patients (SCREEN).

Yaseen M Arabi, Ramesh Kumar Vishwakarma, Hasan M Al-Dorzi, Eman Al Qasim, Sheryl Ann Abdukahil, Fawaz K Al-Rabeah, Huda Al Ghamdi, Ebtisam Al Ghamdi, ,

<h4>Background</h4>It is unclear whether screening for sepsis using an electronic alert in hospitalized ward patients improves outcomes. The objective of the Stepped-wedge Cluster Randomized Trial of Electronic Early Notification of Sepsis in Hospitalized Ward Patients (SCREEN) trial is to evaluate whether an electronic screening for sepsis compared to no screening ... Read more >>

Trials (Trials)
[2021, 22(1):828]

Cited: 0 times

View full text PDF listing >>



Infection control in the intensive care unit: expert consensus statements for SARS-CoV-2 using a Delphi method.

Prashant Nasa, Elie Azoulay, Arunaloke Chakrabarti, Jigeeshu V Divatia, Ravi Jain, Camilla Rodrigues, Victor D Rosenthal, Waleed Alhazzani, Yaseen M Arabi, Jan Bakker, Matteo Bassetti, Jan De Waele, George Dimopoulos, Bin Du, Sharon Einav, Laura Evans, Simon Finfer, Claude Guérin, Naomi E Hammond, Samir Jaber, Ruth M Kleinpell, Younsuck Koh, Marin Kollef, Mitchell M Levy, Flavia R Machado, Jordi Mancebo, Ignacio Martin-Loeches, Mervyn Mer, Michael S Niederman, Paolo Pelosi, Anders Perner, John V Peter, Jason Phua, Lise Piquilloud, Mathias W Pletz, Andrew Rhodes, Marcus J Schultz, Mervyn Singer, Jéan-François Timsit, Balasubramanian Venkatesh, Jean-Louis Vincent, Tobias Welte, Sheila N Myatra,

During the current COVID-19 pandemic, health-care workers and uninfected patients in intensive care units (ICUs) are at risk of being infected with SARS-CoV-2 as a result of transmission from infected patients and health-care workers. In the absence of high-quality evidence on the transmission of SARS-CoV-2, clinical practice of infection control ... Read more >>

Lancet Infect Dis (The Lancet. Infectious diseases)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Nutrition support for critically ill patients.

Hasan M Al-Dorzi, Yaseen M Arabi,

Nutrition support is an important aspect of the management of critically ill patients. This review highlights the emerging evidence on critical care nutrition and focuses on the pathophysiologic interplay between critical illness, the gastrointestinal tract, and nutrition support and the evidence on the best route, dose, and timing of nutrition. ... Read more >>

JPEN J Parenter Enteral Nutr (JPEN. Journal of parenteral and enteral nutrition)
[2021, 45(S2):47-59]

Cited: 0 times

View full text PDF listing >>



Case presentation and panel discussion: Critical illness.

Manpreet S Mundi, Jayshil J Patel, Jeffrey I Mechanick, Yaseen M Arabi, John Alverdy, Zudin Puthucheary, Stephen A McClave,

Despite a mounting evidentiary base, controversies surrounding critical care nutrition support persist. Anchored by a case of a 60-year-old male with esophageal cancer who develops acute hypoxemic respiratory failure and septic shock, five panelists from the American Society of Parenteral and Enteral Nutrition (ASPEN) 2021 Pre-Conference discuss key clinical dilemmas ... Read more >>

JPEN J Parenter Enteral Nutr (JPEN. Journal of parenteral and enteral nutrition)
[2021, 45(S2):79-84]

Cited: 0 times

View full text PDF listing >>



Outcomes of septic cirrhosis patients admitted to the intensive care unit: A retrospective cohort study.

Ralphe Bou Chebl, Hani Tamim, Musharaf Sadat, Saad Qahtani, Tarek Dabbagh, Yaseen M Arabi,

<h4>Abstract</h4>The aim of this study is to examine the outcome of septic patients with cirrhosis admitted to the intensive care unit (ICU) and predictors of mortality.Single center, retrospective cohort study.The study was conducted in Intensive care Department of King Abdulaziz Medical City, Riyadh, Saudi Arabia.Data was extracted from a prospectively ... Read more >>

Medicine (Baltimore) (Medicine)
[2021, 100(46):e27593]

Cited: 0 times

View full text PDF listing >>



Outcomes of tracheostomy in COVID-19 patients in National Guard Health Affairs, Riyadh, Saudi Arabia.

Salwa ALHumaid, Mohammed A Elkrim, Yazeed A AlOqaili, Ghada A AlSowailmi, Fahad A AlObaid, Abdulaziz A AlSalem, Mohammed A AlQabasani, Yaseen M Arabi, Hasan M AlDorzi,

<h4>Objectives</h4>To evaluate coronavirus disease 2019 (COVID-19) patient tracheostomy outcomes.<h4>Methods</h4>All COVID-19 patients at the National Guard Hospital, Riyadh, Saudi Arabia, were retrospectively recruited. Those who had tracheostomies between April and December 2020 were included.<h4>Results</h4>The population was 45 patients, of which 30 (66.7%) were males, 15 (33.3%) were females and the mean ... Read more >>

Saudi Med J (Saudi medical journal)
[2021, 42(11):1217-1222]

Cited: 0 times

View full text PDF listing >>



The Saudi Critical Care Society practice guidelines on the management of COVID-19 in the ICU: Therapy section.

Waleed Alhazzani, Mohammed Alshahrani, Fayez Alshamsi, Ohoud Aljuhani, Khalid Eljaaly, Samaher Hashim, Rakan Alqahtani, Doaa Alsaleh, Zainab Al Duhailib, Haifa Algethamy, Tariq Al-Musawi, Thamir Alshammari, Abdullah Alqarni, Danya Khoujah, Wail Tashkandi, Talal Dahhan, Najla Almutairi, Haleema A Alserehi, Maytha Al-Yahya, Bandar Al-Judaibi, Yaseen M Arabi, Jameel Abualenain, Jawaher M Alotaibi, Ali Al Bshabshe, Reham Alharbi, Fahad Al-Hameed, Alyaa Elhazmi, Reem S Almaghrabi, Fatma Almaghlouth, Malak Abedalthagafi, Noor Al Khathlan, Faisal A Al-Suwaidan, Reem F Bunyan, Bandar Baw, Ghassan Alghamdi, Manal Al Hazmi, Yasser Mandourah, Abdullah Assiri, Mushira Enani, Maha Alawi, Reem Aljindan, Ahmed Aljabbary, Abdullah Alrbiaan, Fahd Algurashi, Abdulmohsen Alsaawi, Thamer H Alenazi, Mohammed A Alsultan, Saleh A Alqahtani, Ziad Memish, Jaffar A Al-Tawfiq, Ahmed Al-Jedai,

<h4>Background</h4>The rapid increase in coronavirus disease 2019 (COVID-19) cases during the subsequent waves in Saudi Arabia and other countries prompted the Saudi Critical Care Society (SCCS) to put together a panel of experts to issue evidence-based recommendations for the management of COVID-19 in the intensive care unit (ICU).<h4>Methods</h4>The SCCS COVID-19 ... Read more >>

J Infect Public Health (Journal of infection and public health)
[2022, 15(1):142-151]

Cited: 0 times

View full text PDF listing >>



The REMDACTA trial: do interleukin receptor antagonists provide additional benefit in COVID-19?

Kate C Tatham, Manu Shankar-Hari, Yaseen M Arabi,

Intensive Care Med (Intensive care medicine)
[2021, 47(11):1315-1318]

Cited: 0 times

View full text PDF listing >>



The story of critical care in Asia: a narrative review.

Jason Phua, Chae-Man Lim, Mohammad Omar Faruq, Khalid Mahmood Khan Nafees, Bin Du, Charles D Gomersall, Lowell Ling, Jigeeshu Vasishtha Divatia, Seyed Mohammad Reza Hashemian, Moritoki Egi, Aidos Konkayev, Mohd Basri Mat-Nor, Gentle Sunder Shrestha, Madiha Hashmi, Jose Emmanuel M Palo, Yaseen M Arabi, Hon Liang Tan, Rohan Dissanayake, Ming-Cheng Chan, Chairat Permpikul, Boonsong Patjanasoontorn, Do Ngoc Son, Masaji Nishimura, Younsuck Koh, ,

<h4>Background</h4>Asia has more critically ill people than any other part of our planet. The aim of this article is to review the development of critical care as a specialty, critical care societies and education and research, the epidemiology of critical illness as well as epidemics and pandemics, accessibility and cost ... Read more >>

J Intensive Care (Journal of intensive care)
[2021, 9(1):60]

Cited: 0 times

View full text PDF listing >>



Cardiovascular SOFA score may not reflect current practice.

Kaspar F Bachmann, Yaseen M Arabi, Adrian Regli, Joel Starkopf, Annika Reintam Blaser,

Intensive Care Med (Intensive care medicine)
[2022, 48(1):119-120]

Cited: 0 times

View full text PDF listing >>



Managing critical care during COVID-19 pandemic: The experience of an ICU of a tertiary care hospital.

Hasan M Al-Dorzi, Abdulaziz S Aldawood, Amal Almatrood, Victoria Burrows, Brintha Naidu, John D Alchin, Haifaa Alhumedi, Nabeeha Tashkandi, Hamdan Al-Jahdali, Arif Hussain, Mohammed K Al Harbi, Muayed Al Zaibag, Salih Bin Salih, Majid M Al Shamrani, Abdulmohsen Alsaawi, Yaseen M Arabi,

<h4>Background</h4>The COVID-19 pandemic has strained ICUs worldwide. To learn from our experience, we described the critical care response to the outbreak.<h4>Methods</h4>This is a case study of the response of the Intensive Care Department (75-bed capacity) at a tertiary-care hospital to COVID-19 pandemic, which resulted in a high number of critically ... Read more >>

J Infect Public Health (Journal of infection and public health)
[2021, 14(11):1635-1641]

Cited: 1 time

View full text PDF listing >>



Electronic early notification of sepsis in hospitalized ward patients: a study protocol for a stepped-wedge cluster randomized controlled trial.

Yaseen M Arabi, Abdulmohsen Alsaawi, Mohammed Al Zahrani, Ali M Al Khathaami, Raed H AlHazme, Abdullah Al Mutrafy, Ali Al Qarni, Ahmed Al Shouabi, Eman Al Qasim, Sheryl Ann Abdukahil, Fawaz K Al-Rabeah, Huda Al Ghamdi, Ebtisam Al Ghamdi, Mariam Alansari, Khadega A Abuelgasim, Abdulaleem Alatassi, John Alchin, Hasan M Al-Dorzi, Abdulaziz A Ghamdi, Fahad Al-Hameed, Ahmad Alharbi, Mohamed Hussein, Wasil Jastaniah, Mufareh Edah AlKatheri, Hassan AlMarhabi, Hani T Mustafa, Joan Jones, Saad Al-Qahtani, Shaher Qahtani, Ahmad S Qureshi, Salih Bin Salih, Nahar Alselaim, Nabiha Tashkandi, Ramesh Kumar Vishwakarma, Emad AlWafi, Ali H Alyami, Zeyad Alyousef, ,

<h4>Background</h4>To evaluate the effect of screening for sepsis using an electronic sepsis alert vs. no alert in hospitalized ward patients on 90-day in-hospital mortality.<h4>Methods</h4>The SCREEN trial is designed as a stepped-wedge cluster randomized controlled trial. Hospital wards (total of 45 wards, constituting clusters in this design) are randomized to have active alert ... Read more >>

Trials (Trials)
[2021, 22(1):695]

Cited: 1 time

View full text PDF listing >>



COVID-19 Critical Care Simulations: An International Cross-Sectional Survey.

Mohamad-Hani Temsah, Abdulkarim Alrabiaah, Ayman Al-Eyadhy, Fahad Al-Sohime, Abdullah Al Huzaimi, Nurah Alamro, Khalid Alhasan, Vaibhavi Upadhye, Amr Jamal, Fadi Aljamaan, Ali Alhaboob, Yaseen M Arabi, Marc Lazarovici, Ali M Somily, Abdulaziz M Boker,

<b>Objective:</b> To describe the utility and patterns of COVID-19 simulation scenarios across different international healthcare centers. <b>Methods:</b> This is a cross-sectional, international survey for multiple simulation centers team members, including team-leaders and healthcare workers (HCWs), based on each center's debriefing reports from 30 countries in all WHO regions. The main ... Read more >>

Front Public Health (Frontiers in public health)
[2021, 9:700769]

Cited: 0 times

View full text PDF listing >>



Effect of Convalescent Plasma on Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial.

, Lise J Estcourt, Alexis F Turgeon, Zoe K McQuilten, Bryan J McVerry, Farah Al-Beidh, Djillali Annane, Yaseen M Arabi, Donald M Arnold, Abigail Beane, Philippe Bégin, Wilma van Bentum-Puijk, Lindsay R Berry, Zahra Bhimani, Janet E Birchall, Marc J M Bonten, Charlotte A Bradbury, Frank M Brunkhorst, Meredith Buxton, Jeannie L Callum, Michaël Chassé, Allen C Cheng, Matthew E Cove, James Daly, Lennie Derde, Michelle A Detry, Menno De Jong, Amy Evans, Dean A Fergusson, Matthew Fish, Mark Fitzgerald, Claire Foley, Herman Goossens, Anthony C Gordon, Iain B Gosbell, Cameron Green, Rashan Haniffa, Heli Harvala, Alisa M Higgins, Thomas E Hills, Veronica C Hoad, Christopher Horvat, David T Huang, Cara L Hudson, Nao Ichihara, Emma Laing, Abigail A Lamikanra, François Lamontagne, Patrick R Lawler, Kelsey Linstrum, Edward Litton, Elizabeth Lorenzi, Sheila MacLennan, John Marshall, Daniel F McAuley, John F McDyer, Anna McGlothlin, Shay McGuinness, Gail Miflin, Stephanie Montgomery, Paul R Mouncey, Srinivas Murthy, Alistair Nichol, Rachael Parke, Jane C Parker, Nicole Priddee, Damian F J Purcell, Luis F Reyes, Peter Richardson, Nancy Robitaille, Kathryn M Rowan, Jennifer Rynne, Hiroki Saito, Marlene Santos, Christina T Saunders, Ary Serpa Neto, Christopher W Seymour, Jon A Silversides, Alan A Tinmouth, Darrell J Triulzi, Anne M Turner, Frank van de Veerdonk, Timothy S Walsh, Erica M Wood, Scott Berry, Roger J Lewis, David K Menon, Colin McArthur, Ryan Zarychanski, Derek C Angus, Steve A Webb, David J Roberts, Manu Shankar-Hari,

<h4>Importance</h4>The evidence for benefit of convalescent plasma for critically ill patients with COVID-19 is inconclusive.<h4>Objective</h4>To determine whether convalescent plasma would improve outcomes for critically ill adults with COVID-19.<h4>Design, setting, and participants</h4>The ongoing Randomized, Embedded, Multifactorial, Adaptive Platform Trial for Community-Acquired Pneumonia (REMAP-CAP) enrolled and randomized 4763 adults with suspected or ... Read more >>

JAMA (JAMA)
[2021, :]

Cited: 3 times

View full text PDF listing >>



Incidence, outcomes, and predictors of Acinetobacter infection in Saudi Arabian critical care units.

Ayman Kharaba, Haifa Algethamy, Mohamed Hussein, Fahad M Al-Hameed, Adnan Alghamdi, Ammar Hamdan, Jehan Fatani, Alyaa Elhazmi, Hassan Alkhalaf, Basem Barghash, Ahmad Elsawy, Yaseen M Arabi, ,

<h4>Background</h4>Acinetobacter is an increasingly-problematic organism, especially in intensive care units (ICUs). In this study, we compared its incidence, outcomes, and predictors spanning eight ICUs in five geographically and climatologically-diverse cities in Saudi Arabia.<h4>Methods</h4>Geographic, climatologic, hospital-related, and patient-related factors were collected prospectively on 3179 patients admitted to eight Saudi ICUs from ... Read more >>

J Crit Care (Journal of critical care)
[2021, 66:109-116]

Cited: 0 times

View full text PDF listing >>



Effect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients: A Randomized Clinical Trial.

Jennie Johnstone, Maureen Meade, François Lauzier, John Marshall, Erick Duan, Joanna Dionne, Yaseen M Arabi, Diane Heels-Ansdell, Lehana Thabane, Daphnee Lamarche, Michael Surette, Nicole Zytaruk, Sangeeta Mehta, Peter Dodek, Lauralyn McIntyre, Shane English, Bram Rochwerg, Tim Karachi, William Henderson, Gordon Wood, Daniel Ovakim, Margaret Herridge, John Granton, M Elizabeth Wilcox, Alberto Goffi, Henry T Stelfox, Daniel Niven, John Muscedere, François Lamontagne, Frédérick D'Aragon, Charles St-Arnaud, Ian Ball, Dave Nagpal, Martin Girard, Pierre Aslanian, Emmanuel Charbonney, David Williamson, Wendy Sligl, Jan Friedrich, Neill K Adhikari, François Marquis, Patrick Archambault, Kosar Khwaja, Arnold Kristof, James Kutsogiannis, Ryan Zarychanski, Bojan Paunovic, Brenda Reeve, François Lellouche, Paul Hosek, Jennifer Tsang, Alexandra Binnie, Sébastien Trop, Osama Loubani, Richard Hall, Robert Cirone, Steve Reynolds, Paul Lysecki, Eyal Golan, Rodrigo Cartin-Ceba, Robert Taylor, Deborah Cook, ,

<h4>Importance</h4>Growing interest in microbial dysbiosis during critical illness has raised questions about the therapeutic potential of microbiome modification with probiotics. Prior randomized trials in this population suggest that probiotics reduce infection, particularly ventilator-associated pneumonia (VAP), although probiotic-associated infections have also been reported.<h4>Objective</h4>To evaluate the effect of Lactobacillus rhamnosus GG on ... Read more >>

JAMA (JAMA)
[2021, 326(11):1024-1033]

Cited: 3 times

View full text PDF listing >>



Helmet Non-Invasive Ventilation for COVID-19 Patients (Helmet-COVID): study protocol for a multicentre randomised controlled trial.

Yaseen M Arabi, Haytham Tlayjeh, Sara Aldekhyl, Hasan M Al-Dorzi, Sheryl Ann Abdukahil, Mohammad Khulaif Al Harbi, Husain Al Haji, Mohammed Al Mutairi, Omar Al Zumai, Eman Al Qasim, Wedyan Al Wehaibi, Saad Al Qahtani, Fahad Al-Hameed, Jamal Chalabi, Mohammed Alshahrani, Talal Albrahim, Abdulrahman Alharthy, Ahmed Mady, Abdulhadi Bin Eshaq, Ali A Al Bshabshe, Zohair Al Aseri, Zainab Al Duhailib, Ayman Kharaba, Rakan Alqahtani, Adnan Al Ghamdi, Ali Altalag, Khalid Alghamdi, Mohammed Almaani, Haifa Algethamy, Ahmad Al Aqeily, Faisal Al Baseet, Hashem Al Samannoudi, Mohammed Al Obaidi, Yassin T Ismaiel, Abdulrahman A Al-Fares,

<h4>Introduction</h4>Non-invasive ventilation (NIV) delivered by helmet has been used for respiratory support of patients with acute hypoxaemic respiratory failure due to COVID-19 pneumonia. The aim of this study was to compare helmet NIV with usual care versus usual care alone to reduce mortality.<h4>Methods and analysis</h4>This is a multicentre, pragmatic, parallel ... Read more >>

BMJ Open (BMJ open)
[2021, 11(8):e052169]

Cited: 0 times

View full text PDF listing >>



Advertisement


Disclaimer

1.4248 s