Full Text Journal Articles by
Author Yaseen Arabi

Advertisement

Find full text journal articles






Sepsis in end-stage renal disease patients: are they at an increased risk of mortality?

Ralphe Bou Chebl, Hani Tamim, Gilbert Abou Dagher, Musharaf Sadat, Ghassan Ghamdi, Abdulrahman Itani, Alawi Saeedi, Yaseen M Arabi,

<h4>Objectives</h4>This study aims to examine the outcome of end-stage renal disease (ESRD) patients admitted with sepsis to the intensive care unit (ICU).<h4>Design</h4>Single centre, retrospective cohort study.<h4>Setting</h4>The study was conducted in the Intensive Care Department of King Abdulaziz Medical City, Riyadh, Saudi Arabia.<h4>Participants</h4>Data were extracted from a prospectively collected ICU database ... Read more >>

Ann Med (Annals of medicine)
[2021, 53(1):1737-1743]

Cited: 0 times

View full text PDF listing >>



The REMDACTA trial: do interleukin receptor antagonists provide additional benefit in COVID-19?

Kate C Tatham, Manu Shankar-Hari, Yaseen M Arabi,

Intensive Care Med (Intensive care medicine)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Advertisement

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021.

Laura Evans, Andrew Rhodes, Waleed Alhazzani, Massimo Antonelli, Craig M Coopersmith, Craig French, Flávia R Machado, Lauralyn Mcintyre, Marlies Ostermann, Hallie C Prescott, Christa Schorr, Steven Simpson, W Joost Wiersinga, Fayez Alshamsi, Derek C Angus, Yaseen Arabi, Luciano Azevedo, Richard Beale, Gregory Beilman, Emilie Belley-Cote, Lisa Burry, Maurizio Cecconi, John Centofanti, Angel Coz Yataco, Jan De Waele, R Phillip Dellinger, Kent Doi, Bin Du, Elisa Estenssoro, Ricard Ferrer, Charles Gomersall, Carol Hodgson, Morten Hylander Møller, Theodore Iwashyna, Shevin Jacob, Ruth Kleinpell, Michael Klompas, Younsuck Koh, Anand Kumar, Arthur Kwizera, Suzana Lobo, Henry Masur, Steven McGloughlin, Sangeeta Mehta, Yatin Mehta, Mervyn Mer, Mark Nunnally, Simon Oczkowski, Tiffany Osborn, Elizabeth Papathanassoglou, Anders Perner, Michael Puskarich, Jason Roberts, William Schweickert, Maureen Seckel, Jonathan Sevransky, Charles L Sprung, Tobias Welte, Janice Zimmerman, Mitchell Levy,

Crit Care Med (Critical care medicine)
[2021, 49(11):e1063-e1143]

Cited: 0 times

View full text PDF listing >>



Executive Summary: Surviving Sepsis Campaign: International Guidelines for the Management of Sepsis and Septic Shock 2021.

Laura Evans, Andrew Rhodes, Waleed Alhazzani, Massimo Antonelli, Craig M Coopersmith, Craig French, Flávia R Machado, Lauralyn Mcintyre, Marlies Ostermann, Hallie C Prescott, Christa Schorr, Steven Simpson, W Joost Wiersinga, Fayez Alshamsi, Derek C Angus, Yaseen Arabi, Luciano Azevedo, Richard Beale, Gregory Beilman, Emilie Belley-Cote, Lisa Burry, Maurizio Cecconi, John Centofanti, Angel Coz Yataco, Jan De Waele, R Phillip Dellinger, Kent Doi, Bin Du, Elisa Estenssoro, Ricard Ferrer, Charles Gomersall, Carol Hodgson, Morten Hylander Møller, Theodore Iwashyna, Shevin Jacob, Ruth Kleinpell, Michael Klompas, Younsuck Koh, Anand Kumar, Arthur Kwizera, Suzana Lobo, Henry Masur, Steven McGloughlin, Sangeeta Mehta, Yatin Mehta, Mervyn Mer, Mark Nunnally, Simon Oczkowski, Tiffany Osborn, Elizabeth Papathanassoglou, Anders Perner, Michael Puskarich, Jason Roberts, William Schweickert, Maureen Seckel, Jonathan Sevransky, Charles L Sprung, Tobias Welte, Janice Zimmerman, Mitchell Levy,

Crit Care Med (Critical care medicine)
[2021, 49(11):1974-1982]

Cited: 0 times

View full text PDF listing >>



Cardiovascular SOFA score may not reflect current practice.

Kaspar F Bachmann, Yaseen M Arabi, Adrian Regli, Joel Starkopf, Annika Reintam Blaser,

Intensive Care Med (Intensive care medicine)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Managing critical care during COVID-19 pandemic: The experience of an ICU of a tertiary care hospital.

Hasan M Al-Dorzi, Abdulaziz S Aldawood, Amal Almatrood, Victoria Burrows, Brintha Naidu, John D Alchin, Haifaa Alhumedi, Nabeeha Tashkandi, Hamdan Al-Jahdali, Arif Hussain, Mohammed K Al Harbi, Muayed Al Zaibag, Salih Bin Salih, Majid M Al Shamrani, Abdulmohsen Alsaawi, Yaseen M Arabi,

<h4>Background</h4>The COVID-19 pandemic has strained ICUs worldwide. To learn from our experience, we described the critical care response to the outbreak.<h4>Methods</h4>This is a case study of the response of the Intensive Care Department (75-bed capacity) at a tertiary-care hospital to COVID-19 pandemic, which resulted in a high number of critically ... Read more >>

J Infect Public Health (Journal of infection and public health)
[2021, 14(11):1635-1641]

Cited: 0 times

View full text PDF listing >>



The story of critical care in Asia: a narrative review.

Jason Phua, Chae-Man Lim, Mohammad Omar Faruq, Khalid Mahmood Khan Nafees, Bin Du, Charles D Gomersall, Lowell Ling, Jigeeshu Vasishtha Divatia, Seyed Mohammad Reza Hashemian, Moritoki Egi, Aidos Konkayev, Mohd Basri Mat-Nor, Gentle Sunder Shrestha, Madiha Hashmi, Jose Emmanuel M Palo, Yaseen M Arabi, Hon Liang Tan, Rohan Dissanayake, Ming-Cheng Chan, Chairat Permpikul, Boonsong Patjanasoontorn, Do Ngoc Son, Masaji Nishimura, Younsuck Koh, ,

<h4>Background</h4>Asia has more critically ill people than any other part of our planet. The aim of this article is to review the development of critical care as a specialty, critical care societies and education and research, the epidemiology of critical illness as well as epidemics and pandemics, accessibility and cost ... Read more >>

J Intensive Care (Journal of intensive care)
[2021, 9(1):60]

Cited: 0 times

View full text PDF listing >>



COVID-19 Critical Care Simulations: An International Cross-Sectional Survey.

Mohamad-Hani Temsah, Abdulkarim Alrabiaah, Ayman Al-Eyadhy, Fahad Al-Sohime, Abdullah Al Huzaimi, Nurah Alamro, Khalid Alhasan, Vaibhavi Upadhye, Amr Jamal, Fadi Aljamaan, Ali Alhaboob, Yaseen M Arabi, Marc Lazarovici, Ali M Somily, Abdulaziz M Boker,

<b>Objective:</b> To describe the utility and patterns of COVID-19 simulation scenarios across different international healthcare centers. <b>Methods:</b> This is a cross-sectional, international survey for multiple simulation centers team members, including team-leaders and healthcare workers (HCWs), based on each center's debriefing reports from 30 countries in all WHO regions. The main ... Read more >>

Front Public Health (Frontiers in public health)
[2021, 9:700769]

Cited: 0 times

View full text PDF listing >>



Electronic early notification of sepsis in hospitalized ward patients: a study protocol for a stepped-wedge cluster randomized controlled trial.

Yaseen M Arabi, Abdulmohsen Alsaawi, Mohammed Al Zahrani, Ali M Al Khathaami, Raed H AlHazme, Abdullah Al Mutrafy, Ali Al Qarni, Ahmed Al Shouabi, Eman Al Qasim, Sheryl Ann Abdukahil, Fawaz K Al-Rabeah, Huda Al Ghamdi, Ebtisam Al Ghamdi, Mariam Alansari, Khadega A Abuelgasim, Abdulaleem Alatassi, John Alchin, Hasan M Al-Dorzi, Abdulaziz A Ghamdi, Fahad Al-Hameed, Ahmad Alharbi, Mohamed Hussein, Wasil Jastaniah, Mufareh Edah AlKatheri, Hassan AlMarhabi, Hani T Mustafa, Joan Jones, Saad Al-Qahtani, Shaher Qahtani, Ahmad S Qureshi, Salih Bin Salih, Nahar Alselaim, Nabiha Tashkandi, Ramesh Kumar Vishwakarma, Emad AlWafi, Ali H Alyami, Zeyad Alyousef, ,

<h4>Background</h4>To evaluate the effect of screening for sepsis using an electronic sepsis alert vs. no alert in hospitalized ward patients on 90-day in-hospital mortality.<h4>Methods</h4>The SCREEN trial is designed as a stepped-wedge cluster randomized controlled trial. Hospital wards (total of 45 wards, constituting clusters in this design) are randomized to have active alert ... Read more >>

Trials (Trials)
[2021, 22(1):695]

Cited: 0 times

View full text PDF listing >>



Effect of Convalescent Plasma on Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial.

, Lise J Estcourt, Alexis F Turgeon, Zoe K McQuilten, Bryan J McVerry, Farah Al-Beidh, Djillali Annane, Yaseen M Arabi, Donald M Arnold, Abigail Beane, Philippe Bégin, Wilma van Bentum-Puijk, Lindsay R Berry, Zahra Bhimani, Janet E Birchall, Marc J M Bonten, Charlotte A Bradbury, Frank M Brunkhorst, Meredith Buxton, Jeannie L Callum, Michaël Chassé, Allen C Cheng, Matthew E Cove, James Daly, Lennie Derde, Michelle A Detry, Menno De Jong, Amy Evans, Dean A Fergusson, Matthew Fish, Mark Fitzgerald, Claire Foley, Herman Goossens, Anthony C Gordon, Iain B Gosbell, Cameron Green, Rashan Haniffa, Heli Harvala, Alisa M Higgins, Thomas E Hills, Veronica C Hoad, Christopher Horvat, David T Huang, Cara L Hudson, Nao Ichihara, Emma Laing, Abigail A Lamikanra, François Lamontagne, Patrick R Lawler, Kelsey Linstrum, Edward Litton, Elizabeth Lorenzi, Sheila MacLennan, John Marshall, Daniel F McAuley, John F McDyer, Anna McGlothlin, Shay McGuinness, Gail Miflin, Stephanie Montgomery, Paul R Mouncey, Srinivas Murthy, Alistair Nichol, Rachael Parke, Jane C Parker, Nicole Priddee, Damian F J Purcell, Luis F Reyes, Peter Richardson, Nancy Robitaille, Kathryn M Rowan, Jennifer Rynne, Hiroki Saito, Marlene Santos, Christina T Saunders, Ary Serpa Neto, Christopher W Seymour, Jon A Silversides, Alan A Tinmouth, Darrell J Triulzi, Anne M Turner, Frank van de Veerdonk, Timothy S Walsh, Erica M Wood, Scott Berry, Roger J Lewis, David K Menon, Colin McArthur, Ryan Zarychanski, Derek C Angus, Steve A Webb, David J Roberts, Manu Shankar-Hari,

<h4>Importance</h4>The evidence for benefit of convalescent plasma for critically ill patients with COVID-19 is inconclusive.<h4>Objective</h4>To determine whether convalescent plasma would improve outcomes for critically ill adults with COVID-19.<h4>Design, setting, and participants</h4>The ongoing Randomized, Embedded, Multifactorial, Adaptive Platform Trial for Community-Acquired Pneumonia (REMAP-CAP) enrolled and randomized 4763 adults with suspected or ... Read more >>

JAMA (JAMA)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021.

Laura Evans, Andrew Rhodes, Waleed Alhazzani, Massimo Antonelli, Craig M Coopersmith, Craig French, Flávia R Machado, Lauralyn Mcintyre, Marlies Ostermann, Hallie C Prescott, Christa Schorr, Steven Simpson, W Joost Wiersinga, Fayez Alshamsi, Derek C Angus, Yaseen Arabi, Luciano Azevedo, Richard Beale, Gregory Beilman, Emilie Belley-Cote, Lisa Burry, Maurizio Cecconi, John Centofanti, Angel Coz Yataco, Jan De Waele, R Phillip Dellinger, Kent Doi, Bin Du, Elisa Estenssoro, Ricard Ferrer, Charles Gomersall, Carol Hodgson, Morten Hylander Møller, Theodore Iwashyna, Shevin Jacob, Ruth Kleinpell, Michael Klompas, Younsuck Koh, Anand Kumar, Arthur Kwizera, Suzana Lobo, Henry Masur, Steven McGloughlin, Sangeeta Mehta, Yatin Mehta, Mervyn Mer, Mark Nunnally, Simon Oczkowski, Tiffany Osborn, Elizabeth Papathanassoglou, Anders Perner, Michael Puskarich, Jason Roberts, William Schweickert, Maureen Seckel, Jonathan Sevransky, Charles L Sprung, Tobias Welte, Janice Zimmerman, Mitchell Levy,

Intensive Care Med (Intensive care medicine)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Therapeutics for COVID-19

Yaseen M. Arabi,

Int J Antimicrob Agents (International journal of antimicrobial agents)
[2021, 58(3):21002387-21002387]

Cited: 0 times

View full text PDF listing >>



Incidence, outcomes, and predictors of Acinetobacter infection in Saudi Arabian critical care units.

Ayman Kharaba, Haifa Algethamy, Mohamed Hussein, Fahad M Al-Hameed, Adnan Alghamdi, Ammar Hamdan, Jehan Fatani, Alyaa Elhazmi, Hassan Alkhalaf, Basem Barghash, Ahmad Elsawy, Yaseen M Arabi, ,

<h4>Background</h4>Acinetobacter is an increasingly-problematic organism, especially in intensive care units (ICUs). In this study, we compared its incidence, outcomes, and predictors spanning eight ICUs in five geographically and climatologically-diverse cities in Saudi Arabia.<h4>Methods</h4>Geographic, climatologic, hospital-related, and patient-related factors were collected prospectively on 3179 patients admitted to eight Saudi ICUs from ... Read more >>

J Crit Care (Journal of critical care)
[2021, 66:109-116]

Cited: 0 times

View full text PDF listing >>



Case presentation and panel discussion: critical illness.

Manpreet Mundi, Jayshil Patel, Jeffrey I Mechanick, Yaseen M Arabi, John Alverdy, Zudin Puthucheary, Stephen A McClave,

Despite a mounting evidentiary base, controversies surrounding critical care nutrition support persist. Anchored by a case of a 60-year-old male with esophageal cancer who develops acute hypoxemic respiratory failure and septic shock, five panelists from the ASPEN 2021 Pre-Conference discuss key clinical dilemmas in critical care nutrition, including hierarchy of ... Read more >>

JPEN J Parenter Enteral Nutr (JPEN. Journal of parenteral and enteral nutrition)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Effect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients: A Randomized Clinical Trial.

Jennie Johnstone, Maureen Meade, François Lauzier, John Marshall, Erick Duan, Joanna Dionne, Yaseen M Arabi, Diane Heels-Ansdell, Lehana Thabane, Daphnee Lamarche, Michael Surette, Nicole Zytaruk, Sangeeta Mehta, Peter Dodek, Lauralyn McIntyre, Shane English, Bram Rochwerg, Tim Karachi, William Henderson, Gordon Wood, Daniel Ovakim, Margaret Herridge, John Granton, M Elizabeth Wilcox, Alberto Goffi, Henry T Stelfox, Daniel Niven, John Muscedere, François Lamontagne, Frédérick D'Aragon, Charles St-Arnaud, Ian Ball, Dave Nagpal, Martin Girard, Pierre Aslanian, Emmanuel Charbonney, David Williamson, Wendy Sligl, Jan Friedrich, Neill K Adhikari, François Marquis, Patrick Archambault, Kosar Khwaja, Arnold Kristof, James Kutsogiannis, Ryan Zarychanski, Bojan Paunovic, Brenda Reeve, François Lellouche, Paul Hosek, Jennifer Tsang, Alexandra Binnie, Sébastien Trop, Osama Loubani, Richard Hall, Robert Cirone, Steve Reynolds, Paul Lysecki, Eyal Golan, Rodrigo Cartin-Ceba, Robert Taylor, Deborah Cook, ,

<h4>Importance</h4>Growing interest in microbial dysbiosis during critical illness has raised questions about the therapeutic potential of microbiome modification with probiotics. Prior randomized trials in this population suggest that probiotics reduce infection, particularly ventilator-associated pneumonia (VAP), although probiotic-associated infections have also been reported.<h4>Objective</h4>To evaluate the effect of Lactobacillus rhamnosus GG on ... Read more >>

JAMA (JAMA)
[2021, 326(11):1024-1033]

Cited: 0 times

View full text PDF listing >>



Venous Thromboembolism Prophylaxis in Critically Ill Adults: A Systematic Review and Network Meta-analysis.

Shannon M Fernando, Alexandre Tran, Wei Cheng, Behnam Sadeghirad, Yaseen M Arabi, Deborah J Cook, Morten Hylander Møller, Sangeeta Mehta, Robert A Fowler, Karen E A Burns, Philip S Wells, Marc Carrier, Mark A Crowther, Damon C Scales, Shane W English, Kwadwo Kyeremanteng, Salmaan Kanji, Michelle E Kho, Bram Rochwerg,

<h4>Background</h4>Critically ill adults are at increased risk of VTE, including DVT, and pulmonary embolism. Various agents exist for venous thromboprophylaxis in this population.<h4>Research question</h4>What is the comparative efficacy and safety of prophylaxis agents for prevention of VTE in critically ill adults?<h4>Study design and methods</h4>Systematic review and network meta-analysis of randomized ... Read more >>

Chest (Chest)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Helmet Non-Invasive Ventilation for COVID-19 Patients (Helmet-COVID): study protocol for a multicentre randomised controlled trial.

Yaseen M Arabi, Haytham Tlayjeh, Sara Aldekhyl, Hasan M Al-Dorzi, Sheryl Ann Abdukahil, Mohammad Khulaif Al Harbi, Husain Al Haji, Mohammed Al Mutairi, Omar Al Zumai, Eman Al Qasim, Wedyan Al Wehaibi, Saad Al Qahtani, Fahad Al-Hameed, Jamal Chalabi, Mohammed Alshahrani, Talal Albrahim, Abdulrahman Alharthy, Ahmed Mady, Abdulhadi Bin Eshaq, Ali A Al Bshabshe, Zohair Al Aseri, Zainab Al Duhailib, Ayman Kharaba, Rakan Alqahtani, Adnan Al Ghamdi, Ali Altalag, Khalid Alghamdi, Mohammed Almaani, Haifa Algethamy, Ahmad Al Aqeily, Faisal Al Baseet, Hashem Al Samannoudi, Mohammed Al Obaidi, Yassin T Ismaiel, Abdulrahman A Al-Fares,

<h4>Introduction</h4>Non-invasive ventilation (NIV) delivered by helmet has been used for respiratory support of patients with acute hypoxaemic respiratory failure due to COVID-19 pneumonia. The aim of this study was to compare helmet NIV with usual care versus usual care alone to reduce mortality.<h4>Methods and analysis</h4>This is a multicentre, pragmatic, parallel ... Read more >>

BMJ Open (BMJ open)
[2021, 11(8):e052169]

Cited: 0 times

View full text PDF listing >>



Awake Prone Position in Hypoxemic Patients with Coronavirus Disease 19 (COVI-PRONE): A Study protocol and Statistical Analysis Plan for Randomized Clinical Trial

Zainab Al Duhailib, Yaseen Arabi, Sarah Culgin, Jason Weatherald, Ken Kuljit Parhar, Kate Nelson, Hani Tamim, Waleed Alhazzani, ,

<h4>Background</h4> Coronavirus disease 2019 (COVID-19), may progress to respiratory failure requiring invasive mechanical ventilation. Due to ventilator shortage and healthcare systems strain, affordable interventions such as awake prone positioning has been used to improve oxygenation, however, the effect of this intervention on patient-important outcomes is uncertain. The COVI-PRONE trial aims ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Favipiravir and Hydroxychloroquine Combination Therapy in Patients with Moderate to Severe COVID-19 (FACCT Trial): An Open-Label, Multicenter, Randomized, Controlled Trial.

Mohammad Bosaeed, Ebrahim Mahmoud, Ahmad Alharbi, Hadeel Altayib, Hawra Albayat, Faisal Alharbi, Khalid Ghalilah, Abdulmajid Al Arfaj, Jumana AlJishi, Abdullatif Alarfaj, Hajar Alqahtani, Badriah M Almutairi, Manar Almaghaslah, Nawaf M Alyahya, Abdullah Bawazir, Saud AlEisa, Abdulrahman Alsaedy, Abderrezak Bouchama, Malak Alharbi, Majid AlShamrani, Sameera Al Johani, Majed Aljeraisy, Mohammed Alzahrani, Abdulhakeem O Althaqafi, Hassan Almarhabi, Athari Alotaibi, Nasser Alqahtani, Yaseen M Arabi, Omar S Aldibasi, Ahmad Alaskar,

<h4>Introduction</h4>Antiviral drugs have shown limited effectiveness in treating patients with coronavirus disease 2019 (COVID-19). We aimed to assess the effects of a favipiravir and hydroxychloroquine combination on treating moderate-to-severe COVID-19 patients.<h4>Methods</h4>An investigator-initiated, multicenter, open-label, randomized trial at nine hospitals. Eligible patients were adults with moderate-to-severe COVID-19 defined as oxygen saturation ... Read more >>

Infect Dis Ther (Infectious diseases and therapy)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19.

, , , Patrick R Lawler, Ewan C Goligher, Jeffrey S Berger, Matthew D Neal, Bryan J McVerry, Jose C Nicolau, Michelle N Gong, Marc Carrier, Robert S Rosenson, Harmony R Reynolds, Alexis F Turgeon, Jorge Escobedo, David T Huang, Charlotte A Bradbury, Brett L Houston, Lucy Z Kornblith, Anand Kumar, Susan R Kahn, Mary Cushman, Zoe McQuilten, Arthur S Slutsky, Keri S Kim, Anthony C Gordon, Bridget-Anne Kirwan, Maria M Brooks, Alisa M Higgins, Roger J Lewis, Elizabeth Lorenzi, Scott M Berry, Lindsay R Berry, Aaron W Aday, Farah Al-Beidh, Djillali Annane, Yaseen M Arabi, Diptesh Aryal, Lisa Baumann Kreuziger, Abi Beane, Zahra Bhimani, Shailesh Bihari, Henny H Billett, Lindsay Bond, Marc Bonten, Frank Brunkhorst, Meredith Buxton, Adrian Buzgau, Lana A Castellucci, Sweta Chekuri, Jen-Ting Chen, Allen C Cheng, Tamta Chkhikvadze, Benjamin Coiffard, Todd W Costantini, Sophie de Brouwer, Lennie P G Derde, Michelle A Detry, Abhijit Duggal, Vladimír Džavík, Mark B Effron, Lise J Estcourt, Brendan M Everett, Dean A Fergusson, Mark Fitzgerald, Robert A Fowler, Jean P Galanaud, Benjamin T Galen, Sheetal Gandotra, Sebastian García-Madrona, Timothy D Girard, Lucas C Godoy, Andrew L Goodman, Herman Goossens, Cameron Green, Yonatan Y Greenstein, Peter L Gross, Naomi M Hamburg, Rashan Haniffa, George Hanna, Nicholas Hanna, Sheila M Hegde, Carolyn M Hendrickson, R Duncan Hite, Alexander A Hindenburg, Aluko A Hope, James M Horowitz, Christopher M Horvat, Kristin Hudock, Beverley J Hunt, Mansoor Husain, Robert C Hyzy, Vivek N Iyer, Jeffrey R Jacobson, Devachandran Jayakumar, Norma M Keller, Akram Khan, Yuri Kim, Andrei L Kindzelski, Andrew J King, M Margaret Knudson, Aaron E Kornblith, Vidya Krishnan, Matthew E Kutcher, Michael A Laffan, Francois Lamontagne, Grégoire Le Gal, Christine M Leeper, Eric S Leifer, George Lim, Felipe Gallego Lima, Kelsey Linstrum, Edward Litton, Jose Lopez-Sendon, Jose L Lopez-Sendon Moreno, Sylvain A Lother, Saurabh Malhotra, Miguel Marcos, Andréa Saud Marinez, John C Marshall, Nicole Marten, Michael A Matthay, Daniel F McAuley, Emily G McDonald, Anna McGlothlin, Shay P McGuinness, Saskia Middeldorp, Stephanie K Montgomery, Steven C Moore, Raquel Morillo Guerrero, Paul R Mouncey, Srinivas Murthy, Girish B Nair, Rahul Nair, Alistair D Nichol, Brenda Nunez-Garcia, Ambarish Pandey, Pauline K Park, Rachael L Parke, Jane C Parker, Sam Parnia, Jonathan D Paul, Yessica S Pérez González, Mauricio Pompilio, Matthew E Prekker, John G Quigley, Natalia S Rost, Kathryn Rowan, Fernanda O Santos, Marlene Santos, Mayler Olombrada Santos, Lewis Satterwhite, Christina T Saunders, Roger E G Schutgens, Christopher W Seymour, Deborah M Siegal, Delcio G Silva, Manu Shankar-Hari, John P Sheehan, Aneesh B Singhal, Dayna Solvason, Simon J Stanworth, Tobias Tritschler, Anne M Turner, Wilma van Bentum-Puijk, Frank L van de Veerdonk, Sean van Diepen, Gloria Vazquez-Grande, Lana Wahid, Vanessa Wareham, Bryan J Wells, R Jay Widmer, Jennifer G Wilson, Eugene Yuriditsky, Fernando G Zampieri, Derek C Angus, Colin J McArthur, Steven A Webb, Michael E Farkouh, Judith S Hochman, Ryan Zarychanski,

<h4>Background</h4>Thrombosis and inflammation may contribute to the risk of death and complications among patients with coronavirus disease 2019 (Covid-19). We hypothesized that therapeutic-dose anticoagulation may improve outcomes in noncritically ill patients who are hospitalized with Covid-19.<h4>Methods</h4>In this open-label, adaptive, multiplatform, controlled trial, we randomly assigned patients who were hospitalized with ... Read more >>

N Engl J Med (The New England journal of medicine)
[2021, 385(9):790-802]

Cited: 17 times

View full text PDF listing >>



Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19: A Meta-analysis.

, Manu Shankar-Hari, Claire L Vale, Peter J Godolphin, David Fisher, Julian P T Higgins, Francesca Spiga, Jelena Savovic, Jayne Tierney, Gabriel Baron, Julie S Benbenishty, Lindsay R Berry, Niklas Broman, Alexandre Biasi Cavalcanti, Roos Colman, Stefanie L De Buyser, Lennie P G Derde, Pere Domingo, Sharifah Faridah Omar, Ana Fernandez-Cruz, Thijs Feuth, Felipe Garcia, Rosario Garcia-Vicuna, Isidoro Gonzalez-Alvaro, Anthony C Gordon, Richard Haynes, Olivier Hermine, Peter W Horby, Nora K Horick, Kuldeep Kumar, Bart N Lambrecht, Martin J Landray, Lorna Leal, David J Lederer, Elizabeth Lorenzi, Xavier Mariette, Nicolas Merchante, Nor Arisah Misnan, Shalini V Mohan, Michael C Nivens, Jarmo Oksi, Jose A Perez-Molina, Reuven Pizov, Raphael Porcher, Simone Postma, Reena Rajasuriar, Athimalaipet V Ramanan, Philippe Ravaud, Pankti D Reid, Abraham Rutgers, Aranzazu Sancho-Lopez, Todd B Seto, Sumathi Sivapalasingam, Arvinder Singh Soin, Natalie Staplin, John H Stone, Garth W Strohbehn, Jonas Sunden-Cullberg, Julian Torre-Cisneros, Larry W Tsai, Hubert van Hoogstraten, Tom van Meerten, Viviane Cordeiro Veiga, Peter E Westerweel, Srinivas Murthy, Janet V Diaz, John C Marshall, Jonathan A C Sterne,

<h4>Importance</h4>Clinical trials assessing the efficacy of IL-6 antagonists in patients hospitalized for COVID-19 have variously reported benefit, no effect, and harm.<h4>Objective</h4>To estimate the association between administration of IL-6 antagonists compared with usual care or placebo and 28-day all-cause mortality and other outcomes.<h4>Data sources</h4>Trials were identified through systematic searches of electronic ... Read more >>

JAMA (JAMA)
[2021, 326(6):499-518]

Cited: 11 times

View full text PDF listing >>



Mechanical Ventilation Discontinuation Practices in Asia: A Multinational Survey.

Chi Hung Czarina Leung, Anna Lee, Yaseen M Arabi, Jason Phua, Jigeeshu V Divatia, Younsuck Koh, Bin Du, Cheng Cheng Tan, Jose Emmanuel M Palo, Karen E A Burns, Tae-Hyung Kim, Moritoki Egi, Mohammad Omar Faruq, Babu Raja Shrestha, Shih-Feng Liu, Tuan Dang Nguyen, Bambang Wahjuprajitno, Madiha Hashmi, Boonsong Patjanasoontorn, Zulaidi Latif, Kanishka Indraratna, Hussain N Al Rahma, Seyed Mohammad Reza Hashemian, Charles D Gomersall,

<b>Rationale:</b> There are limited data on mechanical discontinuation practices in Asia. <b>Objectives:</b> To document self-reported mechanical discontinuation practices and determine whether there is clinical equipoise regarding protocolized weaning among Asian Intensive Care specialists. <b>Methods:</b> A survey using a validated questionnaire, distributed using a snowball method to Asian Intensive Care specialists. ... Read more >>

Ann Am Thorac Soc (Annals of the American Thoracic Society)
[2021, 18(8):1352-1359]

Cited: 2 times

View full text PDF listing >>



How COVID-19 will change the management of other respiratory viral infections.

Yaseen M Arabi, Lennie P G Derde, Jean-François Timsit,

Intensive Care Med (Intensive care medicine)
[2021, 47(10):1148-1151]

Cited: 0 times

View full text PDF listing >>



Statistical Analysis Plan for the Helmet Non-Invasive Ventilation for COVID-19 Patients (Helmet-COVID) Randomized Controlled Trial

Yaseen Arabi, Haytham Tlayjeh, Sara Aldekhyl, Hasan Al-Dorzi, Sheryl Ann Abdukahil, Jesna Jose, Mohammad Khulaif Al Harbi, Husain Al Haji, Mohammed Al Mutairi, Omar Al Zumai, Eman Al Qasim, Wedyan Al Wehaibi, Saad Al Qahtani, Mohammed Alshahrani, Talal Albrahim, Ahmed Mady, Ali Al Bshabshe, Zohair Al Aseri, Zainab Al Duhailib, Ayman Kharaba, Rakan Alqahtani, Haifa Algethamy, Omar Alfaris, Omar Alnafel, Abdulrahman Al-Fares,

<h4>Background and objective</h4> Noninvasive respiratory support is frequently needed for patients with acute hypoxemic respiratory failure due to coronavirus disease 19 (COVID-19). Helmet noninvasive ventilation having multiple advantages over other support modalities but data about effectiveness are limited. <h4>Methods</h4> In this multicenter randomized trial of helmet non-invasive ventilation for COVID-19 ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Helmet noninvasive ventilation for COVID-19 patients “Helmet-COVID”: study protocol for a multicenter randomized controlled trial

Yaseen Arabi, Haytham Tlayjeh, Sara Aldekhyl, Hasan Al-Dorzi, Sheryl Ann Abdukahil, Mohammad Khulaif Al Harbi, Husain Al Haji, Mohammed Al Mutairi, Omar Al Zumai, Eman Al Qasim, Wedyan Al Wehaibi, Saad Al Qahtani, Fahad Al-Hameed, Jamal Chalabi, Mohammed Alshahrani, Abdulrahman Alharthy, Ahmed Mady, Abdulhadi Bin Eshaq, Ali Al Bshabshe, Zohair Al Aseri, Zainab Al Duhailib, Ayman Kharaba, Rakan Alqahtani, Adnan Al Ghamdi, Ali Altalag, Khalid Alghamdi, Mohammed Almaani, Haifa Algethamy, Ahmad Al Aqeily, Faisal Al Baseet, Hashem Al Samannoudi, Mohammed Al Obaidi, Yassin Ismaiel, Abdulrahman Al-Fares,

<h4>Introduction</h4> Noninvasive ventilation delivered by helmet is has been used for respiratory support of patients with acute hypoxemic respiratory failure due to COVID-19 pneumonia. The aim of this study is to compare helmet noninvasive ventilation with usual care versus usual care alone to reduce the mortality. <h4>Methods and analysis</h4> This ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Advertisement


Disclaimer

1.9009 s