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Author Yanyan Du

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Paeonol promotes Opa1-mediated mitochondrial fusion via activating the CK2α-Stat3 pathway in diabetic cardiomyopathy.

Chaoyang Liu, Yuehu Han, Xiaoming Gu, Man Li, Yanyan Du, Na Feng, Juan Li, Shumiao Zhang, Leonid N Maslov, Guoen Wang, Jianming Pei, Feng Fu, Mingge Ding,

Diabetes disrupts mitochondrial function and often results in diabetic cardiomyopathy (DCM). Paeonol is a bioactive compound that has been reported to have pharmacological potential for cardiac and mitochondrial protection. This study aims to explore the effects of paeonol on mitochondrial disorderes in DCM and the underlying mechanisms. We showed that ... Read more >>

Redox Biol (Redox biology)
[2021, 46:102098]

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Punicalagin Protects Against Diabetic Cardiomyopathy by Promoting Opa1-Mediated Mitochondrial Fusion via Regulating PTP1B-Stat3 Pathway.

Feng Fu, Chaoyang Liu, Rui Shi, Man Li, Min Zhang, Yanyan Du, Qiaojuan Wang, Jun Li, Guoen Wang, Jianming Pei, Mingge Ding,

<b><i>Aims:</i></b> This study aims to explore the efficacy of punicalagin (PG) on diabetic cardiomyopathy (DCM), with a specific focus on the mechanisms underlying the effects of PG on mitochondrial fusion/fission dynamics. <b><i>Results:</i></b> Cardiac structural and functional abnormalities were ameliorated in diabetic rats receiving PG administration as evidenced by increased ejection ... Read more >>

Antioxid Redox Signal (Antioxidants & redox signaling)
[2021, 35(8):618-641]

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DNA Barcoding Reveals Cryptic Diversity in the Underestimated Genus Triplophysa (Cypriniformes: Cobitidae, Nemacheilinae) from the Northeastern Qinghai-Tibet Plateau

tai wang, Yanping Zhang, Zhuoyu Yang, Zhe Liu, Yanyan Du,

<h4>Background: </h4> The northeastern part of the Qinghai-Tibet Plateau (QTP) presents a high number of plateau loach species. As one of the three major groups of fishes distributed on the QTP, plateau loach has high ecological value. However, the taxonomy and systematics of these fish are still controversial, and a ... Read more >>

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Interaction Kinetics of Peptide Lipids-Mediated Gene Delivery

Yinan Zhao, Tianyi Zhao, Yanyan Du, Yingnan Cao, Yang Xuan, Huiying Chen, Defu Zhi, Shutao Guo, Fangli Zhong, Shubiao Zhang,

<h4>Background: </h4> During the course of gene transfection, the interaction kinetics between liposomes and DNA is speculated to play very important role for blood stability, cellular uptake, DNA release and finally transfection efficiency. <h4>Results: </h4>: As cationic peptide liposomes exhibited great gene transfer activities both in vitro and in vivo, ... Read more >>

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Approximation of invariant measure for a stochastic population model with Markov chain and diffusion in a polluted environment.

Ting Kang, Yanyan Du, Ming Ye, Qimin Zhang,

In the paper, we propose a novel stochastic population model with Markov chain and diffusion in a polluted environment. Under the condition that the diffusion coefficient satisfies the local Lipschitz condition, we prove the existence and uniqueness of invariant measure for the model. Moreover, we also discuss the existence and ... Read more >>

Math Biosci Eng (Mathematical biosciences and engineering : MBE)
[2020, 17(6):6702-6719]

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Elevated serum uric acid, hyperuricaemia and dietary patterns among adolescents in mainland China.

Hang Zhou, Zheng Feei Ma, Yiming Lu, Yanyan Du, Jian Shao, Liya Wang, Qin Wu, Binyu Pan, Wenxi Zhu, Qihua Zhao, Hua Wei,

Background Elevated serum uric acid concentrations have been associated with metabolic syndrome. However, only limited information is available on the prevalence of hyperuricaemia in adolescents. Therefore, the aim of our cross-sectional study was to study the prevalence of hyperuricaemia and dietary patterns in adolescents aged 13-16 years living in Yangzhou, ... Read more >>

J Pediatr Endocrinol Metab (Journal of pediatric endocrinology & metabolism : JPEM)
[2020, 33(4):487-493]

Cited: 5 times

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Acid-Triggered Release of Native Gemcitabine Conjugated in Polyketal Nanoparticles for Enhanced Anticancer Therapy.

Haiping Zhong, Jingqing Mu, Yanyan Du, Zunkai Xu, Yang Xu, Na Yu, Shubiao Zhang, Shutao Guo,

Nucleoside analogue drugs are widely used in cancer therapy and antiviral therapy, while fast metabolism, drug resistance, and severe side effects significantly limit their clinical applications. To address these issues, a variety of ester- and amide-linked prodrugs and their nanoparticulate formulations have been devised. However, most of these prodrugs suffer ... Read more >>

Biomacromolecules (Biomacromolecules)
[2020, 21(2):803-814]

Cited: 2 times

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The complete mitochondrial genome sequence and phylogenetic position of Gobio coriparoides.

Yushuang Ge, Qiqun Cheng, Yongbin Yan, Xiaochen Duan, Tai Wang, Yanping Zhang, Zhongyu Lou, Yanyan Du,

In this paper, we determined the complete mitochondrial DNA (mtDNA) sequence of <i>Gobio coriparoides</i> and analyzed its phylogenetic position. The complete mitogenome is 16,604 bp in length. It consists of 13 protein-coding genes, 2 rRNA genes, 22 tRNA genes, and 1 control region. Among the 37 genes, 28 were encoded on ... Read more >>

Mitochondrial DNA B Resour (Mitochondrial DNA. Part B, Resources)
[2020, 5(1):808-809]

Cited: 1 time

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An evolutionarily conserved iron-sulfur cluster underlies redox sensory function of the Chloroplast Sensor Kinase.

Iskander M Ibrahim, Huan Wu, Roman Ezhov, Gilbert E Kayanja, Stanislav D Zakharov, Yanyan Du, Weiguo Andy Tao, Yulia Pushkar, William A Cramer, Sujith Puthiyaveetil,

Photosynthetic efficiency depends on equal light energy conversion by two spectrally distinct, serially-connected photosystems. The redox state of the plastoquinone pool, located between the two photosystems, is a key regulatory signal that initiates acclimatory changes in the relative abundance of photosystems. The Chloroplast Sensor Kinase (CSK) links the plastoquinone redox ... Read more >>

Commun Biol (Communications biology)
[2020, 3(1):13]

Cited: 3 times

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Assessment of Iodine Status among Pregnant Women and Neonates Using Neonatal Thyrotropin (TSH) in Mainland China after the Introduction of New Revised Universal Salt Iodisation (USI) in 2012: A Re-Emergence of Iodine Deficiency?

Hang Zhou, Zheng Feei Ma, Yiming Lu, Binyu Pan, Jian Shao, Liya Wang, Yanyan Du, Qihua Zhao,

Iodine deficiency during pregnancy can cause iodine deficiency disorders (IDD). However, it is unclear about iodine and thyroid status of Chinese pregnant women and neonates after the implementation of the revised universal salt iodisation (USI) level in 2012. Therefore, the aim of the cross-sectional study was to determine iodine nutrition ... Read more >>

Int J Endocrinol (International journal of endocrinology)
[2019, 2019:3618169]

Cited: 3 times

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Effects of sucrose ester structures on liposome-mediated gene delivery.

Yinan Zhao, An Liu, Yanyan Du, Yingnan Cao, Enxia Zhang, Quan Zhou, Hua Hai, Yuhong Zhen, Shubiao Zhang,

Sucrose esters (SEs) have great potential applications in gene delivery because of their low toxicity, excellent biocompatibility, and biodegradability. By using tripeptide-based lipid (CDO) as a model lipid and SEs as helper lipids, a series of liposomes were prepared. The SEs with hydrophilic-lipophilic balance (HLB) values of 1, 6, 11, ... Read more >>

Acta Biomater (Acta biomaterialia)
[2018, 72:278-286]

Cited: 4 times

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Effectiveness and potential risk of CaO application in Cd-contaminated paddy soil.

Yanyan Du, Xin Wang, Xionghui Ji, Zhenxing Zhang, Uttam Kamar Saha, Weicheng Xie, Yunhe Xie, Jiamei Wu, Bo Peng, Changyin Tan,

In this study, the accurate effectiveness of CaO in mitigating Cd bioavailability in paddy soil-rice system was investigated and moreover, the potential for reversibility of CaO liming process was provided. Increasing soil pH to ≥6.5 by CaO was determined to be the minimal threshold for minimizing Cd transfer into rice ... Read more >>

Chemosphere (Chemosphere)
[2018, 204:130-139]

Cited: 1 time

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Metformin ameliorates hypoxia/reoxygenation-induced cardiomyocyte apoptosis based on the SIRT3 signaling pathway.

Yanyan Du, Jingjing Zhang, Fang Fang, Xiqing Wei, Hongsheng Zhang, Hongyong Tan, Jinguo Zhang,

Myocardial hypoxia/reoxygenation (H/R) injury is one of the main causes of death and disability worldwide. However, a limited number of therapies are available to minimize the detrimental effects of this injury. Recently, researchers have demonstrated that metformin exerts direct cardioprotective effects against H/R. The aim of this study was to ... Read more >>

Gene (Gene)
[2017, 626:182-188]

Cited: 7 times

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Graphitic Carbon Nitride (g-C3N4) Nanosheets/Graphene Composites: In Situ Synthesis and Enhanced Photocatalytic Performance.

Kaixing Zhu, Yanyan Du, Jing Liu, Xiaoyan Fan, Zhenya Duan, Guanying Song, Alan Meng, Zhenjiang Li, Qingdang Li,

A facile In Situ growth method was presented here for the preparation of graphitic carbon nitride (g-C3N4)/graphene composites, in which the direct growth and deposition of g-C3N4 nanosheets from organic N and C sources on the graphene surfaces was achieved to form the 3D contacted structure. The resulting 3D architecture ... Read more >>

J Nanosci Nanotechnol (Journal of nanoscience and nanotechnology)
[2017, 17(4):2515-2519]

Cited: 1 time

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Composition dependent magnetic and ferroelectric properties of hydrothermally synthesized GdFe1-xCrxO3 (0.1 ≤ x ≤ 0.9) perovskites.

Yu Qiao, Yanfeng Zhou, Shan Wang, Long Yuan, Yanyan Du, Dayong Lu, Guangbo Che, Huinan Che,

The hydrothermal synthesis and magnetic, dielectric and ferroelectric property characterization of ABO<sub>3</sub>-perovskite GdFe<sub>1-x</sub>Cr<sub>x</sub>O<sub>3</sub> (0 < x < 1) are reported. The mineralizer KOH plays a critical role in the perovskite structure of the sample. The Fe/Cr ratio of the final crystal is controlled by the alkalinity in the initial reaction ... Read more >>

Dalton Trans (Dalton transactions (Cambridge, England : 2003))
[2017, 46(18):5930-5937]

Cited: 0 times

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Mda-7/IL-24 enhances sensitivity of B cell lymphoma to chemotherapy drugs.

Ming Ma, Lianmei Zhao, Guogui Sun, Chao Zhang, Lihua Liu, Yanyan Du, Xingxiao Yang, Baoen Shan,

Interleukin-24 (IL-24) is a cytokine encoded by a tumor suppressor gene of the IL-10 family, also known as the melanoma differentiation associated gene-7 (Mda-7) and first discovered in human melanoma cells. Mda-7/IL-24 has been shown to inhibit the proliferation of various human tumor cell lines, but its effect on the ... Read more >>

Oncol Rep (Oncology reports)
[2016, 35(5):3122-3130]

Cited: 5 times

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Microwave-Assisted Synthesis of Co-Coordinated Hollow Mesoporous Carbon Cubes for Oxygen Reduction Reactions.

Lisong Chen, Xiangzhi Cui, Min Wang, Yanyan Du, Xiaohua Zhang, Gang Wan, Linlin Zhang, Fangming Cui, Chenyang Wei, Jianlin Shi,

Transition-metal-/metal-oxide-loaded mesoporous carbon materials with hollow structures are thought to have great potential as catalysts, especially in the areas of sustainable chemistry and energy conversion. However, it is hard to load transition metals/metal oxides onto carbon materials while keeping the carbon materials unchanged through traditional after-treatment processes, thus making it ... Read more >>

Langmuir (Langmuir : the ACS journal of surfaces and colloids)
[2015, 31(27):7644-7651]

Cited: 1 time

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Mesostructured amorphous manganese oxides: facile synthesis and highly durable elimination of low-concentration NO at room temperature in air.

Yanyan Du, Zile Hua, Weimin Huang, Meiying Wu, Min Wang, Jin Wang, Xiangzhi Cui, Lingxia Zhang, Hangrong Chen, Jianlin Shi,

At a high space velocity of 120 000 mL g(-1) h(-1) and a relative humidity of 50-90%, 98% removal of 10 ppm NO has been achieved for over 237 h and no sign of deactivation was observed with mesostructured amorphous manganese oxides (AMO), due to the prevention of the catalyst active ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2015, 51(27):5887-5889]

Cited: 2 times

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Nitric oxide negatively regulates abscisic acid signaling in guard cells by S-nitrosylation of OST1.

Pengcheng Wang, Yanyan Du, Yueh-Ju Hou, Yang Zhao, Chuan-Chih Hsu, Feijuan Yuan, Xiaohong Zhu, W Andy Tao, Chun-Peng Song, Jian-Kang Zhu,

The phytohormone abscisic acid (ABA) plays important roles in plant development and adaptation to environmental stress. ABA induces the production of nitric oxide (NO) in guard cells, but how NO regulates ABA signaling is not understood. Here, we show that NO negatively regulates ABA signaling in guard cells by inhibiting ... Read more >>

Proc Natl Acad Sci U S A (Proceedings of the National Academy of Sciences of the United States of America)
[2015, 112(2):613-618]

Cited: 97 times

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A salt-assisted acid etching strategy for hollow mesoporous silica/organosilica for pH-responsive drug and gene co-delivery.

Meiying Wu, Yu Chen, Lingxia Zhang, Xiaoyu Li, Xiaojun Cai, Yanyan Du, Linlin Zhang, Jianlin Shi,

A salt-assisted acid etching (SAAE) strategy has been developed to construct rattle/hollow mesoporous silica/organosilica nanovehicles (R/HMSVs or R/HMOVs), which settles the drawbacks of traditional silica etching approaches, such as undesirable by-products, by alkaline etching and strong corrosion of the HF etching process. The hollow structure and phenylene-bridged framework of HMOVs ... Read more >>

J Mater Chem B (Journal of materials chemistry. B)
[2015, 3(5):766-775]

Cited: 2 times

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Lentiviral-mediated overexpression of Akt1 reduces anoxia-reoxygenation injury in cardiomyocytes.

Yanyan Du, Hong Zhu, Dongye Li, Lele Wang, Lin Zhang, Yuanyuan Luo, Defeng Pan, Manman Huang,

Activated PI3K/Akt signalling exerts a protective effect after myocardial ischemia by phosphorylating various substrates; however, the precise mechanism by which this occurs remains to be elucidated. We have constructed the recombinant lentiviral vector pLVX-Akt1-EGFP- 3FLAG (LV-Akt1) to determine the efficiency of LV-Akt1 infection, explore the protective role of Akt1, and ... Read more >>

Cell Biol Int (Cell biology international)
[2014, 38(4):488-496]

Cited: 3 times

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The MPK6-ERF6-ROS-responsive cis-acting Element7/GCC box complex modulates oxidative gene transcription and the oxidative response in Arabidopsis.

Pengcheng Wang, Yanyan Du, Xiaoliang Zhao, Yuchen Miao, Chun-Peng Song,

Reactive oxygen species (ROS) have been characterized as both important signaling molecules and universal stressors that mediate many developmental and physiological responses. So far, details of the transcriptional mechanism of ROS-responsive genes are largely unknown. In the study reported here, we identified seven potential ROS-responsive cis-acting elements (ROSEs) from the ... Read more >>

Plant Physiol (Plant physiology)
[2013, 161(3):1392-1408]

Cited: 67 times

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Determination of iron(III) based on the fluorescence quenching of rhodamine B derivative.

Yanyan Du, Min Chen, Yingxue Zhang, Feng Luo, Chunyan He, Meijin Li, Xi Chen,

A new method for determination of iron(III) has been developed using a kind of rhodamine B derivative fluorescent probe, rhodamine amide (RHA), in acidic HAc-NaAc buffer solution. In this approach, the heavy atom effect of I₃(-) was applied to quench the fluorescence of RHA. When iron(III) and KI coexisted in ... Read more >>

Talanta (Talanta)
[2013, 106:261-265]

Cited: 9 times

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Phosphorylation by MPK6: a conserved transcriptional modification mediates nitrate reductase activation and NO production?

Pengcheng Wang, Yanyan Du, Chun-Peng Song,

Nitrate reductase is a central enzyme of nitrogen assimilation in plants. In a recent work, we have revealed MPK6 could phosphorylate Arabidopsis NIA2 at the serine 627 in hinge 2 region, this phosporylation may represent a rapid activation mechnism when plant need excessive nitrate reduction. Interestingly, all eukaryotic NRs have ... Read more >>

Plant Signal Behav (Plant signaling & behavior)
[2011, 6(6):889-891]

Cited: 9 times

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Photodegradation mechanism and kinetics of methyl orange catalyzed by Fe(III) and citric acid.

Jing Guo, Yanyan Du, Yeqing Lan, Jingdong Mao,

In this study, the photodegradation process of methyl orange (MO) catalyzed by Fe(III) and citric acid and the reaction kinetics were investigated in detail at pHs from 2 to 8. The results show that the photodegradation of MO is slow in the presence of Fe(III) or citric acid alone. However, ... Read more >>

J Hazard Mater (Journal of hazardous materials)
[2011, 186(2-3):2083-2088]

Cited: 10 times

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