Full Text Journal Articles by
Author Yanqing Wang

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DNA topoisomerases as additional targets for anticancer monofunctional platinum(ii) complexes.

Hongmei Zhang, Tao Yang, Yanqing Wang, Zenghui Wang, Zhenzhu Zhu, Zijian Guo, Xiaoyong Wang,

Topoisomerases are ubiquitous enzymes and important targets for DNA-oriented anticancer drugs. Two mitochondrion-targeted monofunctional platinum(ii) complexes, [Pt(ortho-PPh<sub>3</sub>CH<sub>2</sub>Py)(NH<sub>3</sub>)<sub>2</sub>Cl](NO<sub>3</sub>)<sub>2</sub> (OPT) and [Pt(para-PPh<sub>3</sub>CH<sub>2</sub>Py)(NH<sub>3</sub>)<sub>2</sub>Cl](NO<sub>3</sub>)<sub>2</sub> (PPT; PPh<sub>3</sub> = triphenylphosphonium, Py = pyridine), show significant inhibition towards the activity of DNA topoisomerases in addition to their DNA binding and mitochondrial targeting capabilities. OPT exhibits strong cytotoxicity ... Read more >>

Dalton Trans (Dalton transactions (Cambridge, England : 2003))
[2021, 50(1):304-310]

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Vascular smooth muscle cell-specific miRNA-214 knockout inhibits angiotensin II-induced hypertension through upregulation of Smad7.

Youyou Li, Hongxing Li, Wenjuan Xing, Jianwei Li, Ruikai Du, Dengchao Cao, Yinbo Wang, Xueyi Yang, Guohui Zhong, Yinlong Zhao, Weijia Sun, Caizhi Liu, Xingcheng Gao, Yeheng Li, Zizhong Liu, Xiaoyan Jin, Dingsheng Zhao, Yingjun Tan, Yanqing Wang, Shujuan Liu, Min Yuan, Jinping Song, Yan-Zhong Chang, Feng Gao, Shukuan Ling, Yingxian Li,

Vascular remodeling is a prominent trait during the development of hypertension, attributable to the phenotypic transition of vascular smooth muscle cells (VSMCs). Increasing studies demonstrate that microRNA plays an important role in this process. Here, we surprisingly found that smooth muscle cell-specific miR-214 knockout (miR-214 cKO) significantly alleviates angiotensin II ... Read more >>

FASEB J (FASEB journal : official publication of the Federation of American Societies for Experimental Biology)
[2021, 35(11):e21947]

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A neuroanatomical basis for electroacupuncture to drive the vagal-adrenal axis.

Shenbin Liu, Zhifu Wang, Yangshuai Su, Lu Qi, Wei Yang, Mingzhou Fu, Xianghong Jing, Yanqing Wang, Qiufu Ma,

Somatosensory autonomic reflexes allow electroacupuncture stimulation (ES) to modulate body physiology at distant sites<sup>1-6</sup> (for example, suppressing severe systemic inflammation<sup>6-9</sup>). Since the 1970s, an emerging organizational rule about these reflexes has been the presence of body-region specificity<sup>1-6</sup>. For example, ES at the hindlimb ST36 acupoint but not the abdominal ST25 acupoint can ... Read more >>

Nature (Nature)
[2021, :]

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The prevalence and clinical implication of rare germline deleterious alterations in Chinese patients with prostate cancer: A real‐world multicenter study

Xiaochen Fei, Liancheng Fan, Wei Chen, Wei Chen, Yiming Gong, Xinxing Du, Yanqing Wang, Yinjie Zhu, Jiahua Pan, Fangqin Wang, Wanbing Zhao, Tongtong Liu, Yining Yang, Baijun Dong, Wei Xue,

Clin Transl Med (Clinical and translational medicine)
[2021, 11(10):]

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Comparative analysis of the long-term outcomes of segmentectomy and lobectomy for stage IA1 lung adenocarcinoma in patients with or without previous malignancy of other organs: a population-based study.

Wenliang Bai, Jiaqi Zhang, Yanqing Wang, Mengxin Zhou, Lei Liu, Guige Wang, Ke Zhao, Xuehan Gao, Shanqing Li,

<h4>Background</h4>For early stage non-small cell lung cancer, whether limited resection can yield comparable outcomes to those of lobectomy hasn't been established. In this study, we compared Overall survival (OS) and lung cancer-specific survival (LCSS) after segmentectomy or lobectomy in stage IA1 (≤10 mm) lung adenocarcinoma (LUAD) patients.<h4>Research design and methods</h4>We ... Read more >>

Expert Rev Anticancer Ther (Expert review of anticancer therapy)
[2021, :]

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Efficient Exciplex-Based Deep-Blue Organic Light-Emitting Diodes Employing a Bis(4-fluorophenyl)amine-Substituted Heptazine Acceptor.

Jie Li, Heqi Gong, Jincheng Zhang, Hui Liu, Li Tao, Yanqing Wang, Qiang Guo,

The realization of a deep-blue-emitting exciplex system is a herculean task in the field of organic light-emitting diodes (OLEDs) on account of a large red-shifted and broadened exciplex emission spectrum in comparison to those of the corresponding single compounds. Herein, 2,5,8-tris(di(4-fluorophenyl)amine)-1,3,4,6,7,9,9b-heptaazaphenalene (HAP-3FDPA) was designed as an electron acceptor by integrating ... Read more >>

Molecules (Molecules (Basel, Switzerland))
[2021, 26(18):]

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3' untranslated region of Ckip-1 inhibits cardiac hypertrophy independently of its cognate protein.

Yinlong Zhao, Shukuan Ling, Jianwei Li, Guohui Zhong, Ruikai Du, Youyou Li, Yanqing Wang, Caizhi Liu, Xiaoyan Jin, Wei Liu, Tong Liu, Yuheng Li, Dingsheng Zhao, Weijia Sun, Zizhong Liu, Zifan Liu, Junjie Pan, Xinxin Yuan, Xingcheng Gao, Wenjuan Xing, Yan-Zhong Chang, Yingxian Li,

<h4>Aims</h4>3' untranslated region (3' UTR) of mRNA is more conserved than other non-coding sequences in vertebrate genomes, and its sequence space has substantially expanded during the evolution of higher organisms, which substantiates their significance in biological regulation. However, the independent role of 3' UTR in cardiovascular disease was largely unknown.<h4>Methods ... Read more >>

Eur Heart J (European heart journal)
[2021, 42(36):3786-3799]

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The Genome Sequence Archive Family: Toward Explosive Data Growth and Diverse Data Types.

Tingting Chen, Xu Chen, Sisi Zhang, Junwei Zhu, Bixia Tang, Anke Wang, Lili Dong, Zhewen Zhang, Caixia Yu, Yanling Sun, Lianjiang Chi, Huanxin Chen, Shuang Zhai, Yubin Sun, Li Lan, Xin Zhang, Jingfa Xiao, Yiming Bao, Yanqing Wang, Zhang Zhang, Wenming Zhao,

The Genome Sequence Archive (GSA) is a data repository for archiving raw sequence data, which provides data storage and sharing services for worldwide scientific communities. Considering explosive data growth with diverse data types, here we present the GSA family by expanding into a set of resources for raw data archive ... Read more >>

Genomics Proteomics Bioinformatics (Genomics, proteomics & bioinformatics)
[2021, :]

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Case Report: Near-Fatal Intestinal Hemorrhage and Acute Acalculous Cholecystitis due to Vi-Negative and Fluoroquinolone-Insensitive Salmonella enterica Serovar Typhi Infection: A Rare Entity.

Yuehua Gong, Jianlin Li, Dongnan Zhu, Songsong Wang, Yingchun Xu, Yan Li, Yanqing Wang, Yan Song, Wenjuan Liu, Yunlong Tian,

Typhoid fever is usually a mild clinical disease. Typhoid fever with massive intestinal hemorrhage is rare in the antibiotic era. Acute acalculous cholecystitis (AAC) is also rare in adults. Here, we describe the first adult case of typhoid fever with both complications due to Vi-negative and fluoroquinolone-insensitive <i>Salmonella enterica</i> serovar ... Read more >>

Front Med (Lausanne) (Frontiers in medicine)
[2021, 8:666643]

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Incorporation of Layered Rectorite into Biocompatible Core-Sheath Nanofibrous Mats for Sustained Drug Delivery.

Hu Tu, Fangfang Dai, Gu Cheng, Mengqin Yuan, Xue Zhou, Yanqing Wang, Ruquan Zhang, Yajing Zheng, Yanxiang Cheng, Hongbing Deng,

Searching for drug carries with controlled release and good biocompatibility has always been one of the research hotspots and difficulties. Herein, core-sheath nanofibrous mats (NFs) consisting of biocompatible poly(ethylene oxide) (PEO, core) and poly(l-lactic acid) (PLLA, sheath) for drug delivery were fabricated via coaxial electrospinning strategy. The nontoxic layered silicate ... Read more >>

ACS Biomater Sci Eng (ACS biomaterials science & engineering)
[2021, 7(9):4509-4520]

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Imidazolium ionic Liquid-Regulated Sub-5-nm Pt(111) with a stable configuration anchored on hollow carbon nanoshells for efficient oxygen reduction.

Shizhu Song, Qi Li, Lifang Zhang, Yanqing Wang, Xiaojuan Liu,

Here, N-doped hollow carbon sphere (NHCS)-supported (111)-plane-engineered sub-5-nm Pt (Pt-NHCS) catalysts regulated precisely by imidazolium ionic liquids were synthesized successfully and used to catalyze oxygen reduction. The (111)-plane engineered Pt nanocrystals with a diameter of 4.5 ± 0.5 nm were homogeneously deposited on the 3-dimensional spherical nanoshells. The resulting Pt nanocrystals anchored on ... Read more >>

J Colloid Interface Sci (Journal of colloid and interface science)
[2021, 606(Pt 1):177-191]

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Melanoma mimicking atypical fibroxanthoma: Report of an unusual case.

Yanqing Wang, Ying Guo,

Melanoma may mimic a variety of skin lesions clinically and histopathologically, and presents diagnostic challenges. In this article, we describe a case of melanoma in an 89-year-old man with a very rare histopathologic presentation, namely the presence of pleomorphic and multinucleated giant cells with abundant cytoplasm, highly resembling an atypical ... Read more >>

J Cutan Pathol (Journal of cutaneous pathology)
[2021, :]

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Prevalence and risk factors of worry among teachers during the COVID-19 epidemic in Henan, China: a cross-sectional survey.

Yanqing Wang, Quanman Li, Clifford Silver Tarimo, Cuiping Wu, Yudong Miao, Jian Wu,

<h4>Objective</h4>To evaluate the level of worry and its influencing factors during the COVID-19 epidemic among teachers in Henan Province in China.<h4>Study design</h4>A cross-sectional study was conducted.<h4>Methods</h4>We designed a cross-sectional survey that included 88 611 teachers from three cities in Henan Province, China between 4 February 2020 and 12 February 2020. Level ... Read more >>

BMJ Open (BMJ open)
[2021, 11(7):e045386]

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A Hybrid Retrieval Strategy for Case-based Reasoning Using Soft Likelihood Functions

Yameng Wang, Liguo Fei, Yuqiang Feng, Yanqing Wang, Luning Liu,

Case-based reasoning (CBR) is the retrieval of one or more similar cases from an existing case base for the problem to be solved according to the characteristics of the new problem. The core idea of CBR is that similar cases have similar solutions, so whether the CBR system can play ... Read more >>

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The Genome Sequence Archive Family: Towards Explosive Data Growth and Diverse Data Types

Tingting Chen, Xu Chen, Sisi Zhang, Junwei Zhu, Bixia Tang, Anke Wang, Lili Dong, Zhewen Zhang, Caixia Yu, Yanling Sun, Lianjiang Chi, Huanxin Chen, Shuang Zhai, Yubin Sun, Li Lan, Xin Zhang, Jingfa Xiao, Yiming Bao, Yanqing Wang, Zhang Zhang, Wenming Zhao,

The Genome Sequence Archive (GSA) is a data repository for archiving raw sequence data, which provides data storing and sharing services for worldwide scientific communities. Considering explosive data growth with diverse data types, here we present the GSA family by expanding into a set of resources for raw data archive ... Read more >>

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An Investigation on Machining General Size Cylindrical Parts Using WEDM with Contour Approximation Method

Huliang Ma, Yanqing Wang, Ming Lv, Shengqiang Yang,

The application of wire EDM to the machining of cylindrical parts is an emerging research topic. The current research is mainly focused on the machining of micro-cylindrical parts, and there is little research on the general-sized parts. This paper proposes to apply the principle of contour approximation method to the ... Read more >>

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An Extreme Energy-Saving Carbohydrazide Oxidization Reaction Directly Driven by Commercial Graphite Paper in Alkali and Near-Neutral Seawater Electrolytes.

Yanqing Wang, Gaoyuan Li, Han Yan, Shuyan Chen, Liping Ding,

The energy-saving anode with low oxidization potential has been an intriguing pursue for earth-abundant seawater electrolysis. In this paper, we first introduced a superior energy-saving carbohydrazide oxidization reaction catalysis system in the anode section, which can be driven by commercial graphite paper with good durability. Combining this catalysis reaction and ... Read more >>

ACS Omega (ACS omega)
[2021, 6(24):15737-15741]

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Management of human resources in the green economy: Does green labour productivity matter in low-carbon development in China.

Mansoor Mumtaz Soomro, Yanqing Wang, Raza Ali Tunio, Khamida Aripkhanova, Mohammad Ibrahim Ansari,

Environmentally friendly economic development has become a global concern, whereas the existing literature has ignored the human resources management in the green economy. This study utilizes the basic Cobb-Douglas production function and examines the nonlinear effect of labour productivity on the environment in China. Non-linear findings infer that a positive ... Read more >>

Environ Sci Pollut Res Int (Environmental science and pollution research international)
[2021, :]

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Single Co Atoms Implanted into N-Doped Hollow Carbon Nanoshells with Non-Planar Co-N4-1-O2 Sites for Efficient Oxygen Electrochemistry.

Shizhu Song, Tian Qin, Qi Li, Yanqing Wang, Yanfeng Tang, Lifang Zhang, Xiaojuan Liu,

Facile synthesis of cost-effective carbon-supported Co single atoms (Co-SAs) exhibits huge potential applications in energy storage and conversion devices. We here report the implantation of Co-SAs into hollow carbon spheres (Co-SAs-HCS) via a facile wet-chemistry strategy followed by controlled pyrolysis. Electron-rich histidine acted as a Lewis base effectively immobilizing Co<sup>2+</sup> ... Read more >>

Inorg Chem (Inorganic chemistry)
[2021, 60(10):7498-7509]

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Distinct Response to Platinum-Based Chemotherapy among Patients with Metastatic Castration-Resistant Prostate Cancer Harboring Alterations in Genes Involved in Homologous Recombination.

Liancheng Fan, Xiaochen Fei, Yinjie Zhu, Chenfei Chi, Jiahua Pan, Jianjun Sha, Zhixiang Xin, Yiming Gong, Xinxing Du, Yanqing Wang, Baijun Dong, Wei Xue,

<h4>Purpose</h4>We aimed to explore the association between genomic status and clinical outcome of platinum-based chemotherapy among patients with metastatic castration-resistant prostate cancer (mCRPC).<h4>Materials and methods</h4>We conducted a retrospective study of 55 patients with mCRPC who received platinum-based chemotherapy after the progression to docetaxel chemotherapy and underwent genomic profiling of 14 ... Read more >>

J Urol (The Journal of urology)
[2021, 206(3):630-637]

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Large-scale reconfiguration of connectivity patterns among attentional networks during context-dependent adjustment of cognitive control.

Yilu Li, Yanqing Wang, Fangwen Yu, Antao Chen,

The ability to adjust our behavior flexibly depending on situational demands and changes in the environment is an important characteristic of cognitive control. Previous studies have proved that this type of adaptive control plays a crucial role in selective attention, but have barely explored whether and how attentional networks support ... Read more >>

Hum Brain Mapp (Human brain mapping)
[2021, 42(12):3821-3832]

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The Role of Bone Morphogenetic Protein 4 in Ovarian Function and Diseases.

Dongyong Yang, Xiao Yang, Fangfang Dai, Yanqing Wang, Yi Yang, Min Hu, Yanxiang Cheng,

Bone morphogenetic proteins (BMPs) are the largest subfamily of the transforming growth factor-β (TGF-β) superfamily. BMP4 is a secreted protein that was originally identified due to its role in bone and cartilage development. Over the past decades, extensive literature has indicated that BMP4 and its receptors are widely expressed in ... Read more >>

Reprod Sci (Reproductive sciences (Thousand Oaks, Calif.))
[2021, :]

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Lower surgical Apgar score is predictive on delirium in patients following off-pump coronary artery bypass grafting

Liang Yin, Zhen Zhu, Feichao Bao, Jie Min, Yufeng Zhang, Yi Shen, Yanqing Wang,

<h4>Objective: </h4> To determine the predictive value of surgical Apgar score on delirium postoperatively following OPCABG. Method Intraoperative anesthesia data of patients underwent OPCABG during the period of January 2012 and December 2019 were reviewed and SAS score of each patient was calculated. Relationship between SAS score and postoperative occurrence ... Read more >>

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[Design of Gas Detection System Based on STM32 Infusion Set].

Song Liu, Jun Su, Ling Peng, Bingrong Liu, Cheng Zhou, Yanqing Wang,

Aiming at the low efficiency and low quality detection level of the manual infusion set, a gas detection system for infusion set based on STM32 single-chip microcomputer was designed. The detection system includes hardware system design and software system design. The hardware system is based on the STM32F103 single-chip microcomputer. ... Read more >>

Zhongguo Yi Liao Qi Xie Za Zhi (Zhongguo yi liao qi xie za zhi = Chinese journal of medical instrumentation)
[2021, 45(2):159-162]

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Impact of H-Type Hypertension on Intraplaque Neovascularization Assessed by Contrast-Enhanced Ultrasound.

Yuting Tan, Fang Nie, Guode Wu, Fangzhou Guo, Yanqing Wang, Longli Wang,

<h4>Aim</h4>H-type hypertension is connected with carotid atherosclerotic plaques and stroke, whereas neovascularization is a dominant contributor to plaque vulnerability. However, the correlation between H-type hypertension and plaque vulnerability remains unclear. This study aims to explore the influence of H-type hypertension on intraplaque neovascularization (IPN).<h4>Methods</h4>We enrolled 235 patients with carotid plaques ... Read more >>

J Atheroscler Thromb (Journal of atherosclerosis and thrombosis)
[2021, :]

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