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Performance of TGSE BLADE DWI compared with RESOLVE DWI in the diagnosis of cholesteatoma.

Yaru Sheng, Rujian Hong, Yan Sha, Zhongshuai Zhang, Kun Zhou, Caixia Fu,

BACKGROUND:Based on its high resolution in soft tissue, MRI, especially diffusion-weighted imaging (DWI), is increasingly important in the evaluation of cholesteatoma. The purpose of this study was to evaluate the role of the 2D turbo gradient- and spin-echo (TGSE) diffusion-weighted (DW) pulse sequence with the BLADE trajectory technique in the ... Read more >>

BMC Med Imaging (BMC medical imaging)
[2020, 20(1):40]

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Performance of TGSE BLADE DWI in the diagnosis of cholesteatoma compared with RESOLVE DWI

Yaru Sheng, Rujian Hong, Yan Sha, Zhongshuai Zhang, Kun Zhou, Caixia Fu,

Abstract Background Based on its high resolution in soft tissue, MRI, especially diffusion-weighted imaging (DWI), is increasingly important in the evaluation of cholesteatoma. The purpose of this study was to evaluate the role of the 2D turbo gradient- and spin-echo (TGSE) diffusion-weighted (DW) pulse sequence with the BLADE trajectory technique ... Read more >>

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Utility evaluation of HLA-B*13:01 screening in preventing trichloroethylene-induced hypersensitivity syndrome in a prospective cohort study.

Yufei Dai, Wei Zhou, Qiang Jia, Haiyan Dong, Yong Niu, Jiaxi He, Ping Bin, Juan Yi, Yingping Xiang, Huawei Duan, Huiping Huang, Yan Sha, Meili Shen, Meng Ye, Xianqing Huang, Yuxin Zheng,

OBJECTIVES:Trichloroethylene (TCE) -induced hypersensitivity syndrome (TIHS) is a potentially life-threatening disease. Several genetic susceptibility biomarkers have been found to be associated with TIHS, and this systematic prospective study has been conducted to evaluate the utility of these genetic susceptibility biomarkers in preventing the disease. METHODS:The newly hired TCE-exposed workers were ... Read more >>

Occup Environ Med (Occupational and environmental medicine)
[2020, 77(3):201-206]

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Pseudotumour Cerebri Syndrome in China: A Cohort Study.

Qian Chen, Chaoyi Feng, Guixian Zhao, Weimin Chen, Min Wang, Xinghuai Sun, Yan Sha, Zhenxin Li, Guohong Tian,

Pseudotumour cerebri syndrome (PTCS) remains to be fully investigated in Chinese patients and our study reported PTCS-related clinical differences between Chinese patients and Western patients. This study enrolled 55 consecutive patients (females: 44, median age: 37 y, age range: 14-62 y) with PTCS diagnosed from October 2015 to December 2017. Nine (16.4%, ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):1222]

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Role of Diffusional Kurtosis Imaging in Differentiating Neuromyelitis Optica-Related and Multiple Sclerosis-Related Acute Optic Neuritis: Comparison With Diffusion-Weighted Imaging.

Ping Lu, Ting Yuan, Xilan Liu, Guohong Tian, Jibin Zhang, Yan Sha,

PURPOSE:The discrimination between neuromyelitis optica (NMO)- and multiple sclerosis (MS)-related acute optic neuritis (ON) after the first presentation is difficult in clinical practice. Through a comparison with diffusion-weighted imaging using readout-segmented echo-planar imaging (RESOLVE-DWI), our aim was to determine the feasibility of diffusional kurtosis imaging (DKI) for differential diagnosis. MATERIALS ... Read more >>

J Comput Assist Tomogr (Journal of computer assisted tomography)
[2020, 44(1):47-52]

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Exosomes derived from normal human bronchial epithelial cells down-regulate proliferation and migration of hydroquinone-transformed malignant recipient cells via up-regulating PTEN expression.

Zhenwei Lian, Zuqing Hu, Hongyi Xian, Ran Jiang, Haoyu Huang, Yunxia Jiang, Zhongdaixi Zheng, R Stephen Lloyd, Jianhui Yuan, Yan Sha, Sanming Wang, Dalin Hu,

The gene encoding the tumor suppressor, phosphatase and tensin homolog (PTEN), located on chromosome 10, is frequently expressed at low levels in various tumors, resulting in the stimulation of cell proliferation and migration. However, the role of exosomal PTEN in cell-cell communication during the progress of benzene-induced carcinogenesis remains unclear. ... Read more >>

Chemosphere (Chemosphere)
[2020, 244:125496]

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Comparison of Differences of α-Dicarbonyl Compounds between Naturally Matured and Artificially Heated Acacia Honey: Their Application to Determine Honey Quality.

Sha Yan, Minghui Sun, Lingling Zhao, Kai Wang, Xiaoming Fang, Liming Wu, Xiaofeng Xue,

α-Dicarbonyl compounds (α-DCs) are a major class of intermediates generated during Maillard reactions. They can serve as chemical markers of thermal processing and storage of sugar-rich foods. To distinguish between naturally matured acacia honey (NMAH) and artificially heated acacia honey (AHAH), we purified 12 major α-DCs quinoxaline derivatives to investigate ... Read more >>

J. Agric. Food Chem. (Journal of agricultural and food chemistry)
[2019, 67(46):12885-12894]

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Exosomal miR-221 derived from hydroquinone-transformed malignant human bronchial epithelial cells is involved in cell viability of recipient cells.

Ran Jiang, Haoyu Huang, Zhenwei Lian, Zuqing Hu, R Stephen Lloyd, Daokui Fang, Yanfeng Li, Hongyi Xian, Jianhui Yuan, Yan Sha, Sanming Wang, Dalin Hu,

miR-221, an oncogenic microRNA, can promote cell proliferation and is highly expressed in various types of tumors. However, the role of exosomal miR-221 in benzene-caused carcinogenesis remains elusive. Our study was designed to investigate whether exosomes secreted by the hydroquinone (HQ; an active metabolite of benzene)-transformed malignant cells can transmit ... Read more >>

J Appl Toxicol (Journal of applied toxicology : JAT)
[2020, 40(2):224-233]

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Analysis of improved nutritional composition of bee pollen (Brassica campestris L.) after different fermentation treatments

Sha Yan, Qiangqiang Li, Xiaofeng Xue, Kai Wang, Liuwei Zhao, Liming Wu,

Microbial fermentation as an excellent food processing technology has been used for improving the flavour and nutritional feature of food material. In this study, we compared the differences in the nutrient profile of bee pollen (rape bee pollen, Brassica campestris L., BP) fermented with different species of microbes, such as ... Read more >>

(International Journal of Food Science & Technology)
[2019, 54(6):2169-2181]

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Comprehensive comparison of MR image quality between intratympanic and intravenous gadolinium injection using 3D real IR sequences.

Yang Li, Yan Sha, Feng Wang, Ping Lu, Xilan Liu, Yaru Sheng, Zhongshuai Zhang, Mengxiao Liu,

Background: Intratympanic and intravenous gadolinium administration is used to visualise endolymphatic hydrops. Aims/objectives: The goal of this study was to compare the image quality between intratympanic (IT-method) and intravenous (IV-method) gadolinium administration using three-dimensional inversion recovery with real reconstruction (3D real IR) sequences. Materials and methods: A number of 152 ... Read more >>

Acta Otolaryngol. (Acta oto-laryngologica)
[2019, 139(8):659-664]

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Response to "Drop attacks, hydrops severity and disease duration in hydropic ear disease (Menière's)".

Qianru Wu, Xuanyi Li, Yan Sha, Chunfu Dai,

Eur Arch Otorhinolaryngol (European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery)
[2019, 276(6):1855-1856]

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Clinical features and management of Meniere's disease patients with drop attacks.

Qianru Wu, Xuanyi Li, Yan Sha, Chunfu Dai,

PURPOSE:The aims of the present study are to investigate the variations in clinical features, including medical history, hearing function, vestibular function, and degree of endolymphatic hydrops (EH), in Meniere's disease (MD) patients with and without drop attacks (DAs), and to examine the efficacy of intratympanic gentamicin (ITG) treatment in alleviating ... Read more >>

Eur Arch Otorhinolaryngol (European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery)
[2019, 276(3):665-672]

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Gadolinium-enhanced MRI reveals dynamic development of endolymphatic hydrops in Ménière's disease.

Xuanyi Li, Qianru Wu, Yan Sha, Chunfu Dai, Ru Zhang,

INTRODUCTION:Meniere's disease is associated with impaired hearing, tinnitus, vertigo, and aural fullness. Many anatomical studies have suggested idiopathic endolymphatic hydrops as the pathological basis of Meniere's disease, which now can be visualized by using gadolinium -enhanced magnetic resonance imaging of the inner ear. OBJECTIVE:To investigate the development of endolymphatic hydrops ... Read more >>

Braz J Otorhinolaryngol (Brazilian journal of otorhinolaryngology)
[2020, 86(2):165-173]

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Genetic signatures of plant resistance genes with known function within and between species.

Dan Wang, Yan Sha, Junfeng Hu, Ting Yang, Xue Piao, Xiaohui Zhang,

Plant disease resistance (R) genes have undergone significant evolutionary divergence to cope with rapid changes in pathogens. These highly variable evolutionary patterns may have contributed to diversity in R gene protein families or structures. Here, the evolutionary patterns of 76 identified R genes and their homologs were investigated within and ... Read more >>

Genetica (Genetica)
[2018, 146(6):517-528]

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The Capacity to Buffer and Sustain Imbalanced D-Subgenome Chromosomes by the BBAA Component of Hexaploid Wheat Is an Evolved Dominant Trait.

Xin Deng, Yan Sha, Zhenling Lv, Ying Wu, Ai Zhang, Fang Wang, Bao Liu,

Successful generation of pentaploid wheat (genome, BBAAD) via interspecific hybridization between tetraploid wheat (BBAA) and hexaploid wheat (BBAADD) holds great promise to mutually exchange desirable traits between the two cultivated wheat species, as well as providing a novel facet for evolutionary studies of polyploid wheat. Taking advantage of the viable ... Read more >>

Front Plant Sci (Frontiers in plant science)
[2018, 9:1149]

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Differentiating Neuromyelitis Optica-Related and Multiple Sclerosis-Related Acute Optic Neuritis Using Conventional Magnetic Resonance Imaging Combined With Readout-Segmented Echo-Planar Diffusion-Weighted Imaging.

Ping Lu, Guohong Tian, Xilan Liu, Feng Wang, Zhongshuai Zhang, Yan Sha,

In clinical practice, acute optic neuritis (ON) associated with the development of neuromyelitis optica (NMO) after the first attack is often indistinguishable from that associated with multiple sclerosis (MS). We aimed to determine the optimal combination of features derived from conventional magnetic resonance imaging (MRI) and diffusion-weighted imaging using readout-segmented ... Read more >>

J Comput Assist Tomogr (Journal of computer assisted tomography)
[2018, 42(4):502-509]

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Assessment of lingual sentinel lymph nodes metastases using dual-modal indirect CT/MR lymphography with gold-gadolinium-based nanoprobes in a tongue VX2 carcinoma model.

Yue Yang, Benqing Zhou, Jian Zhou, Xiangyang Shi, Yan Sha, Haitao Wu,

OBJECTIVE:To evaluate the capability of indirect computed tomography and magnetic resonance lymphography (CT/MR-LG) with gadolinium-loaded, polyethylenimine-entrapped gold nanoprobes (Gd-Au PENPs) for assessing lingual sentinel lymph node (SLN) metastasis in a tongue VX2 carcinoma model. MATERIALS AND METHODS:Seventeen rabbits were used to establish a metastatic cervical lymph node model by implanting ... Read more >>

Acta Otolaryngol. (Acta oto-laryngologica)
[2018, 138(8):727-733]

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Correction: Diagnostic and prognostic utilities of humoral fibulin-3 in malignant pleural mesothelioma: Evidence from a meta-analysis.

Dongxu Pei, Yongwei Li, Xinwei Liu, Sha Yan, Xiaolan Guo, Xiaona Xu, Xiaoxia Guo,

[This corrects the article DOI: 10.18632/oncotarget.14712.]. ... Read more >>

Oncotarget (Oncotarget)
[2018, 9(30):21628]

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Comparative genomic analysis of the Lipase3 gene family in five plant species reveals distinct evolutionary origins.

Dan Wang, Lin Zhang, JunFeng Hu, Dianshuai Gao, Xin Liu, Yan Sha,

Lipases are physiologically important and ubiquitous enzymes that share a conserved domain and are classified into eight different families based on their amino acid sequences and fundamental biological properties. The Lipase3 family of lipases was reported to possess a canonical fold typical of α/β hydrolases and a typical catalytic triad, ... Read more >>

Genetica (Genetica)
[2018, 146(2):179-185]

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Modulation of UVB-induced Carcinogenesis by Activation of Alternative DNA Repair Pathways.

Yan Sha, Vladimir Vartanian, Nichole Owen, Stephanie J Mengden Koon, Marcus J Calkins, Courtney S Thompson, Zahra Mirafzali, Sara Mir, Lisa E Goldsmith, Huaping He, Chun Luo, Scott M Brown, Paul W Doetsch, Andy Kaempf, Jeong Y Lim, Amanda K McCullough, R Stephen Lloyd,

The molecular basis for ultraviolet (UV) light-induced nonmelanoma and melanoma skin cancers centers on cumulative genomic instability caused by inefficient DNA repair of dipyrimidine photoproducts. Inefficient DNA repair and subsequent translesion replication past these DNA lesions generate distinct molecular signatures of tandem CC to TT and C to T transitions ... Read more >>

Sci Rep (Scientific reports)
[2018, 8(1):705]

Cited: 4 times

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The Venom of Ornithoctonus huwena affect the electrophysiological stability of neonatal rat ventricular myocytes by inhibiting sodium, potassium and calcium current.

Sha Yan, Pengfei Huang, Ying Wang, Xiongzhi Zeng, Yiya Zhang,

Spider venoms are known to contain various toxins that are used as an effective means to capture their prey or to defend themselves against predators. An investigation of the properties of Ornithoctonus huwena (O.huwena) crude venom found that the venom can block neuromuscular transmission of isolated mouse phrenic nerve-diaphragm and ... Read more >>

Channels (Austin) (Channels (Austin, Tex.))
[2018, 12(1):109-118]

Cited: 2 times

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Methicillin-Sensitive Staphylococcus aureus Suppurative Thyroiditis with Thyrotoxicosis.

Sha Yan, Laryssa Patti,

Intravenous drug use (IVDU) can lead to numerous complications from skin abscesses to bacteremia to endocarditis. Here, we present a rare case of acute suppurative thyroiditis as a complication of IVDU, in which a 26-year-old female with a past medical history of IVDU presented to the emergency department for evaluation ... Read more >>

Case Rep Emerg Med (Case reports in emergency medicine)
[2017, 2017:4018193]

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High-resolution transbulbar ultrasonography helping differentiate intracranial hypertension in bilateral optic disc oedema patients.

Qian Chen, Weimin Chen, Min Wang, Xinghuai Sun, Yan Sha, Zhenxin Li, Guohong Tian,

The enlargement of optic nerve sheath diameter (ONSD) has been proven to be related with raised intracranial pressure (ICP). No prospective study has been focused on utilizing retrobulbar ultrasonography in optic disc oedema patient presented to ophthalmologist.High-resolution transbulbar ultrasonography was performed in a cohort of patient presented with bilateral optic ... Read more >>

Acta Ophthalmol (Acta ophthalmologica)
[2017, 95(6):e481-e485]

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Assessment of Cochlea Endolymphatic Hydrops Using 3-D FLAIR and 3-D Real IR Sequence in Guinea Pigs via 3T MRI After Intratympanic Gadolinium: A Histopathological Comparison.

Feng Wang, Huiying Lyu, Menglong Zhao, Yan Sha, Fang Zhang, Yushu Cheng, Wenhu Huang, Wenlin Tang, Youzhou Xie, Ping Lu,

We assessed whether the three-dimensional fluid-attenuated inversion-recovery (3-D FLAIR) and three-dimensional inversion-recovery with real reconstruction (3-D real IR) sequences can be used to detect cochlea endolymphatic hydrops (EHs) in guinea pigs using 3 Tesla magnetic resonance imaging (3T MRI). The results of 3-D real IR imaging were compared with histopathological outcomes.Fourteen ... Read more >>

Otol. Neurotol. (Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology)
[2017, 38(4):585-590]

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Role of coronal high-resolution diffusion-weighted imaging in acute optic neuritis: a comparison with axial orientation.

Ping Lu, Yan Sha, Hailin Wan, Feng Wang, Guohong Tian,

Through a comparison with the axial orientation, we aimed to evaluate the role of coronal high-resolution diffusion-weighted imaging (DWI) in acute optic neuritis based on diagnostic accuracy and the reproducibility of apparent diffusion coefficient (ADC) measurements.Orbital DWI, using readout-segmented, parallel imaging, and 2D navigator-based reacquisition (RESOLVE-DWI), was performed on 49 ... Read more >>

Neuroradiology (Neuroradiology)
[2017, 59(8):737-745]

Cited: 3 times

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