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Author Yakup Tomak

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The usual course of Thorax CT findings of Covid-19 infection and When should control Thorax CT scan?

Yasemin Gündüz, Mehmet Halil Öztürk, Yakup Tomak,

COVID-19 infection, a highly contagious disease caused by the SARS-CoV virus, and the World Health Organization declared this increasingly spreading disease as a global public health emergency (pandemic). In the diagnosis of COVID-19, the polymerase chain reaction (RT-PCR) is considered as the reference standard test. In the early stages, thorax ... Read more >>

Turk J Med Sci (Turkish journal of medical sciences)
[2020, :]

Cited: 0 times

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Efficacy of convalescent plasma according to blood groups in COVID-19 patients.

Tuba HacibekİroĞlu, Yasİn KalpakÇi, Ahmed Cİhad GenÇ, İlhan HacibekİroĞlu, Cenk Sunu, Adem SaricaoĞlu, Yakup Tomak, OĞuz Karabay, Mehmet KÖroĞlu,

Aim In this study, we aim to investigate the efficacy of convalescent plasma (CP) according to blood groups (BGs) in the treatment of critically ill patients diagnosed with COVID-19. Materials and methods: 28 critically ill and laboratory-confirmed COVID-19 patients who were admitted to intensive care unit (ICU) of Sakarya University, ... Read more >>

Turk J Med Sci (Turkish journal of medical sciences)
[2020, :]

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Effects of dexmedetomidine on new oxidative stress markers on renal ischaemia-reperfusion injury in rats: thiol/disulphide homeostasis and the ischaemia-modified albumin.

Müberra Acar, Havva Sayhan Kaplan, Ali F Erdem, Yakup Tomak, Gupse Turan, Mehmet Özdin,

Objectives: This study investigated the effect of dexmedetomidine on the oxidant-antioxidant (thiol/disulphide) balance.Methods: A total of 24 rats were divided into four groups. The renal arteries in groups IR (ischaemia/reperfusion) and IR + D (ischaemia/reperfusion + dexmedetomidine) were clamped for 45 min and reperfused for 180 min. Groups D (Dexmedetomidine) and IR + D were administered 100 μg/kg dexmedetomidine. ... Read more >>

Arch. Physiol. Biochem. (Archives of physiology and biochemistry)
[2020, :1-6]

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Long-term Clinical Effects of DiscoGel for Cervical Disc Herniation.

Havva Sayhan, Serbülent Gökhan Beyaz, Ali Metin Ülgen, Mehmet Fatih Yuce, Yakup Tomak,

BACKGROUND:Radiopaque gelified ethanol (RGE; DiscoGel, Gelscom SAS, France) is used as a chemonucleolysis substance in treating intradiscal herniation, showing good results without complications. It has also been used in cervical disc herniations (CDHs), demonstrating the potential efficacy of this substance. OBJECTIVE:The aim of the study is to investigate the long-term ... Read more >>

Pain Physician (Pain physician)
[2018, 21(1):E71-E78]

Cited: 2 times

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Comparison of the Intravenous and Epidural Administration of Tumor Necrosis Factor-alpha Antagonists in an Experimental Rat Pain Model.

Serbülent Gökhan Beyaz, Mustafa Erkan İnanmaz, Tolga Ergönenç, Onur Palabıyık, Yakup Tomak, Ayça Taş Tuna,

Introduction:Inflammatory cytokines secreted from the nucleus pulposus are thought to lead to lumbar nerve root compression-like symptoms. Tumor necrosis factor-alpha (TNF-α), an inflammatory cytokine, likely plays an important role in lumbar disc hernia-related leg pain. In this experimental study, we compared the effectiveness of TNF-α antagonists administered through the intravenous ... Read more >>

(Anesthesia, essays and researches)
[2017, 11(4):898-901]

Cited: 1 time

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Does Sugammadex Administration Affect Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy: A Prospective, Double-Blind, Randomized Study.

Ayca Tas Tuna, Onur Palabiyik, Mustafa Orhan, Tugba Sonbahar, Havva Sayhan, Yakup Tomak,

The aim of this study is to assess the effect of sugammadex on postoperative nausea and vomiting (PONV) in patients undergoing laparoscopic cholecystectomy.Eighty patients who were scheduled for elective laparoscopic cholecystectomy surgery were enrolled in this prospective study. Patients were randomly assigned to neostigmine (group N) or sugammadex (group S) ... Read more >>

Surg Laparosc Endosc Percutan Tech (Surgical laparoscopy, endoscopy & percutaneous techniques)
[2017, 27(4):237-240]

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Effect of cooled hyperbaric bupivacaine on unilateral spinal anesthesia success rate and hemodynamic complications in inguinal hernia surgery.

Yakup Tomak, Basar Erdivanli, Ahmet Sen, Habib Bostan, Ersel Tan Budak, Ahmet Pergel,

We hypothesized that cooling hyperbaric bupivacaine from 23 to 5 °C may limit the intrathecal spread of bupivacaine and therefore increase the success rate of unilateral spinal anesthesia and decrease the rate of hemodynamic complications.A hundred patients scheduled for elective unilateral inguinal hernia surgery were randomly allocated to receive 1.8 ml of ... Read more >>

J Anesth (Journal of anesthesia)
[2016, 30(1):26-30]

Cited: 0 times

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Effect of controlled hypotension on regional cerebral oxygen saturation during rhinoplasty: a prospective study.

Ali Fuat Erdem, Gurkan Kayabasoglu, Ayca Tas Tuna, Onur Palabiyik, Yakup Tomak, Serbulent Gokhan Beyaz,

The aim of this study was to investigate the effect of controlled hypotension on cerebral oxygen saturation (rSO2) using near infrared spectroscopy (NIRS) and evaluation of postoperative cognitive function in patients undergoing rhinoplasty. Fifty adult patients who were scheduled for elective rhinoplasty surgery and required controlled hypotension were enrolled in ... Read more >>

J Clin Monit Comput (Journal of clinical monitoring and computing)
[2016, 30(5):655-660]

Cited: 9 times

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A randomized-controlled, double-blind comparison of the postoperative analgesic efficacy of caudal bupivacaine and levobupivacaine in minor pediatric surgery.

Ahmet Sen, Mehmet Salih Colak, Engin Erturk, Yakup Tomak,

BACKGROUND: We compared the postoperative analgesic efficacy of caudal levobupivacaine with bupivacaine in pediatric subumbilical surgery. METHODS: Sixty American Society of Anesthesiologists I-II patients scheduled for elective minor surgery (1.5-7 years old) were randomly divided into three groups to receive caudal injections of study drugs at 0.5 ml/kg. All patients ... Read more >>

Korean J Anesthesiol (Korean journal of anesthesiology)
[2014, 66(6):457-461]

Cited: 1 time

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In vitro evaluation of antimicrobial features of vasopressors.

Habib Bostan, Yakup Tomak, Sengul Alpay Karaoglu, Basar Erdivanli, Volkan Hanci,

BACKGROUND: Drugs administered as intravenous infusion may be contaminated during several stages of production or preparation. However studies focusing on antibacterial effects of vasopressor drugs are very rare. This study investigates the in vitro antimicrobial activity of the clinically used forms of vasopressors. MATERIALS AND METHODS: In vitro antimicrobial activities ... Read more >>

Braz J Anesthesiol (Brazilian journal of anesthesiology (Elsevier))
[2014, 64(2):84-88]

Cited: 1 time

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Community-acquired pneumonia in patients with chronic obstructive pulmonary disease requiring admission to the intensive care unit: risk factors for mortality.

Aykut Cilli, Hakan Erdem, Zuhal Karakurt, Hulya Turkan, Ozlem Yazicioglu-Mocin, Nalan Adiguzel, Gokay Gungor, Ugur Bilge, Canturk Tasci, Gulden Yilmaz, Oral Oncul, Aygul Dogan-Celik, Ozcan Erdemli, Nefise Oztoprak, Anil Aktas Samur, Yakup Tomak, Asuman Inan, Burcu Karaboga, Demet Tok, Sibel Temur, Hafize Oksuz, Ozgur Senturk, Unase Buyukkocak, Fatma Yilmaz-Karadag, Dilek Ozcengiz, Ahmet Karakas, Umit Savasci, Aylin Ozgen-Alpaydın, Erol Kilic, Nazif Elaldi, Hayati Bilgic,

PURPOSE: The aims of this study are to identify factors predicting mortality in patients with chronic obstructive pulmonary disease (COPD) and community-acquired pneumonia (CAP) requiring intensive care unit (ICU) admission and to examine whether noninvasive ventilation treatment reduces mortality. MATERIALS AND METHODS: An analysis was performed on data from patients ... Read more >>

J Crit Care (Journal of critical care)
[2013, 28(6):975-979]

Cited: 16 times

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The interrelations of radiologic findings and mechanical ventilation in community acquired pneumonia patients admitted to the intensive care unit: a multicentre retrospective study.

Hakan Erdem, Zeliha Kocak-Tufan, Omer Yilmaz, Zuhal Karakurt, Aykut Cilli, Hulya Turkan, Ozlem Yazicioglu-Mocin, Nalan Adıguzel, Gokay Gungor, Canturk Taşcı, Gulden Yilmaz, Oral Oncul, Aygul Dogan-Celik, Ozcan Erdemli, Nefise Oztoprak, Yakup Tomak, Asuman Inan, Demet Tok, Sibel Temur, Hafize Oksuz, Ozgur Senturk, Unase Buyukkocak, Fatma Yilmaz-Karadag, Derya Ozturk-Engin, Dilek Ozcengiz, Ahmet Karakas, Hayati Bilgic, Hakan Leblebicioglu,

BACKGROUND: We evaluated patients admitted to the intensive care units with the diagnosis of community acquired pneumonia (CAP) regarding initial radiographic findings. METHODS: A multicenter retrospective study was held. Chest x ray (CXR) and computerized tomography (CT) findings and also their associations with the need of ventilator support were evaluated. ... Read more >>

Ann. Clin. Microbiol. Antimicrob. (Annals of clinical microbiology and antimicrobials)
[2014, 13:5]

Cited: 1 time

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The role of cultural interaction in Tianeptine Abuse and Different Tianeptine Application Methods.

Ahmet Şen, Gökhan İlhan, Yakup Tomak, Başar Erdivanlı, Tahir Ersöz, Murat Şaban Ergene,

Tianeptine is a selective serotonin reuptake enhancer, possessing strong antidepressant and anxiolytic properties. Its relative lack of sedative, anticholinergic and cardiovascular side effects makes it a highly tolerable substance of abuse. However, physical dependence quickly develops and withdrawal symptoms are common. Abusers in Georgia and Armenia use tianeptine by intravenous ... Read more >>

(Turkish journal of anaesthesiology and reanimation)
[2013, 41(6):229-231]

Cited: 0 times

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Effect of sugammadex on rocuronium induced changes in pancreatic mast cells.

Yıldıray Kalkan, Levent Tumkaya, Habib Bostan, Yakup Tomak, Durdu Altuner, Adnan Yilmaz, Başar Erdivanli, Recep Bedir, Alper Yalcin, Alparslan Turan,

Mast cells play a vital role in hypersensitivity reactions. Rocuronium is known to cause mast cell mobilization, hypersensitivity, and pancreatitis. The aim of this study was to investigate the effects of sugammadex on pancreatic changes due to rocuronium. A total of 42 Sprague-Dawley male rats were divided into six equal ... Read more >>

Toxicol Ind Health (Toxicology and industrial health)
[2015, 31(8):738-746]

Cited: 0 times

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Mortality indicators in community-acquired pneumonia requiring intensive care in Turkey.

Hakan Erdem, Hulya Turkan, Aykut Cilli, Ahmet Karakas, Zuhal Karakurt, Uğur Bilge, Ozlem Yazicioglu-Mocin, Nazif Elaldi, Nalan Adıguzel, Gokay Gungor, Canturk Taşcı, Gulden Yilmaz, Oral Oncul, Aygul Dogan-Celik, Ozcan Erdemli, Nefise Oztoprak, Yakup Tomak, Asuman Inan, Burcu Karaboğa, Demet Tok, Sibel Temur, Hafize Oksuz, Ozgur Senturk, Unase Buyukkocak, Fatma Yilmaz-Karadag, Dilek Ozcengiz, Turker Turker, Murat Afyon, Anil Aktas Samur, Asim Ulcay, Umit Savasci, Husrev Diktas, Aylin Ozgen-Alpaydın, Erol Kilic, Hayati Bilgic, Hakan Leblebicioglu, Serhat Unal, Guner Sonmez, Levent Gorenek,

BACKGROUND: Severe community-acquired pneumonia (SCAP) is a fatal disease. This study was conducted to describe an outcome analysis of the intensive care units (ICUs) of Turkey. METHODS: This study evaluated SCAP cases hospitalized in the ICUs of 19 different hospitals between October 2008 and January 2011. The cases of 413 ... Read more >>

Int. J. Infect. Dis. (International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases)
[2013, 17(9):e768-72]

Cited: 3 times

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A novel model approach for esophageal burns in rats: A comparison of three methods.

Yildiray Kalkan, Levent Tumkaya, Remzi Adnan Akdogan, Ahmet Fikret Yucel, Yakup Tomak, İbrahim Sehitoglu, Ahmet Pergel, Aysel Kurt,

Corrosive esophageal injury causes serious clinical problems. We aimed to create a new experimental esophageal burn model using a single catheter without a surgical procedure.We conducted the study with two groups of 12 male rats that fasted for 12 h before application. A modified Foley balloon catheter was inserted into the ... Read more >>

Toxicol Ind Health (Toxicology and industrial health)
[2015, 31(7):595-601]

Cited: 0 times

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Effects of sugammadex on immunoreactivity of calcineurin in rat testes cells after neuromuscular block: a pilot study.

Yıldıray Kalkan, Levent Tümkaya, Habib Bostan, Yakup Tomak, Adnan Yılmaz,

Reversal of neuromuscular blockage induced by steroidal neuromuscular blocking agents such as rocuronium can be achieved using normal dose of sugammadex, which has been shown to be very effective for such reversal. In this study, we determined the effects of sugammadex on calcineurin immunoreactivity by examining the histopathological and histochemical ... Read more >>

J. Mol. Histol. (Journal of molecular histology)
[2012, 43(2):235-241]

Cited: 3 times

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Glutamine supplemented parenteral nutrition to prevent ventilator-associated pneumonia in the intensive care unit.

Meltem Türkay Aydoğmuş, Yakup Tomak, Murat Tekin, Ismail Katı, Urfettin Hüseyinoğlu,

OBJECTIVE: Ventilator-associated pneumonia (VAP) is a form of nosocomial pneumonia that increases patient morbidity and mortality, length of hospital stay, and healthcare costs. Glutamine preserves the intestinal mucosal structure, increases immune function, and reduces harmful changes in gut permeability in patients receiving total parenteral nutrition (TPN). We hypothesized that TPN ... Read more >>

Balkan Med J (Balkan medical journal)
[2012, 29(4):414-418]

Cited: 1 time

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Internal urethrotomy under local urethral anaesthesia is feasible with sedation and analgesia.

Hakki Uzun, Orhan Ünal Zorba, Yakup Tomak, Habip Bostan, Mehmet Kalkan,

BACKGROUND:Urethral stricture is a common condition, and direct vision internal urethrotomy is prefered as the first treatment option by many urologists, for strictures shorter than 2 cm. This procedure is generally performed under general or spinal anaesthesia. OBJECTIVES:To investigate the feasibility of adding local urethral anaesthesia to intravenous sedation and ... Read more >>

(Nephro-urology monthly)
[2012, 4(4):636-639]

Cited: 3 times

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The effect of rocuronium, sugammadex, and their combination on cardiac muscle and diaphragmatic skeletal muscle cells.

Yildiray Kalkan, Habib Bostan, Levent Tumkaya, Yakup Tomak, Mehmet Bostan, Adnan Yilmaz, Hasan Turut, Ahmet Temiz, Alper Yalçin, Alparslan Turan,

Rocuronium has been associated with muscle weakness when administered in prolonged infusions. The effect of sugammadex and rocuronium together on muscle is unknown. In this study, we examined the effects of rocuronium and sugammadex, and the complex formed by these agents, on cardiac and diaphragmatic muscle cells.Forty-two Sprague-Dawley male rats ... Read more >>

J Anesth (Journal of anesthesia)
[2012, 26(6):870-877]

Cited: 3 times

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Analysis of the effect of perioperative magnesium sulphate on minimal alveolar concentration of desflurane using bispectral index monitoring.

Yakup Tomak, Murat Tekin, Ismail Kati, Ceyda Belenli, Meltem Aydogmus,

In this study we aimed to analyze the effect of perioperative magnesium sulphate (MgSO(4)) on minimal alveolar concentration (MAC) of desflurane using bispectral index (BIS) monitoring.Sixty patients undergoing abdominal surgery under general anesthesia were randomized into two groups: Mg - receiving perioperative MgSO(4) supplementation and C - control. Anesthesia was ... Read more >>

Magnes Res (Magnesium research)
[2011, 24(4):181-188]

Cited: 1 time

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Reversal of rocuronium-induced neuromuscular block with sugammadex and resulting histopathological effects in rat kidneys.

Habib Bostan, Yıldıray Kalkan, Yakup Tomak, Levent Tumkaya, Durdu Altuner, Adnan Yılmaz, Baar Erdivanli, Recep Bedir,

BACKGROUND: This study investigated the effect of injection of rocuronium or sugammadex alone and rocuronium + sugammadex on urea, creatinine, electrolyte levels, and histopathological findings in rats. METHODS: Thirty-six Sprague-Dawley male rats were divided to receive intravenously 16 or 96 mg/kg sugammadex, 1 mg/kg rocuronium, 1 mg/kg rocuronium + 16 ... Read more >>

Ren Fail (Renal failure)
[2011, 33(10):1019-1024]

Cited: 6 times

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Comparison of the effects of room air and N2O + O2 used for ProSeal LMA cuff inflation on cuff pressure and oropharyngeal structure.

Murat Tekin, Ismail Kati, Yakup Tomak, Koksal Yuca,

This study aimed to evaluate the effects of different inflating gases used for ProSeal LMA (PLMA) cuff inflation on cuff pressure, oropharyngeal structure, and the incidence of sore throat. Eighty patients (American Society of Anesthesiologists; ASA I-II) were randomly divided into two groups. PLMA cuff inflation was achieved with appropriate ... Read more >>

J Anesth (Journal of anesthesia)
[2008, 22(4):467-470]

Cited: 5 times

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Fibre-optic bronchoscopy-assisted percutaneous dilatational tracheostomy by guidewire dilating forceps in intensive care unit patients.

Köksal Yuca, Ismail Kati, Murat Tekin, Nebi Yilmaz, Yakup Tomak, Hakan Cankaya,

OBJECTIVE: The purpose of this study was to prospectively analyze intensive care unit patients with fibre-optic bronchoscopy-assisted percutaneous dilatational tracheostomy by guidewire dilating forceps (GWDF; Griggs percutaneous tracheostomy). DESIGN: Prospective study. SETTING: A tertiary care centre. MATERIALS AND METHODS: Fifty-two critically ill patients (32 men and 20 women), aged 16 ... Read more >>

J Otolaryngol Head Neck Surg (Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale)
[2008, 37(1):76-80]

Cited: 5 times

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Effect of Dexmedetomidine IV on the Duration of Spinal Anesthesia with Prilocaine: A Double-Blind, Prospective Study in Adult Surgical Patients.

Murat Tekin, Ismail Kati, Yakup Tomak, Erol Kisli,

BACKGROUND: The duration of spinal anesthesia with prilocaine has been poorly documented and no English-language study has been published regarding the effects of dexmedetomidine on the duration of anesthesia with spinal prilocaine. OBJECTIVE: The aim of this study was to assess the effects of dexmedetomidine IV on the duration of ... Read more >>

Curr Ther Res Clin Exp (Current therapeutic research, clinical and experimental)
[2007, 68(5):313-324]

Cited: 15 times

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