Full Text Journal Articles by
Author Xuran Jiang

Advertisement

Find full text journal articles






Relationship Between Nutrition Intake and Outcome After Subarachnoid Hemorrhage: Results From the International Nutritional Survey.

Neeraj Badjatia, Alice Ryan, H Alex Choi, Gunjan Y Parikh, Xuran Jiang, Andrew G Day, Daren K Heyland,

<h4>Background</h4>A previous study suggested an association between low caloric intake(CI), negative nitrogen balance, and poor outcome after subarachnoid hemorrhage(SAH). Objective of this multinational, multicenter study was to investigate whether clinical outcomes vary by protein intake(PI) or CI in SAH patients adjusting for the nutritional risk as judged by the modified ... Read more >>

J Intensive Care Med (Journal of intensive care medicine)
[2021, 36(10):1141-1148]

Cited: 0 times

View full text PDF listing >>



Validation of the modified NUTrition Risk Score (mNUTRIC) in mechanically ventilated, severe burn patients: A prospective multinational cohort study.

L Alfonso Ortiz, Xuran Jiang, Alexis F Turgeon, Lucy Wibbenmeyer, Jonathan Pollack, Samuel P Mandell, Andrew G Day, Daren K Heyland,

<h4>Background</h4>Whether nutrition therapy benefits all burn victims equally is unknown. To identify patients who will benefit the most from optimal nutrition, the modified Nutrition Risk in Critically Ill (mNUTRIC) Score has been validated in the Intensive Care Unit. However, the utility of mNUTRIC in severe burn victims is unknown. We ... Read more >>

Burns (Burns : journal of the International Society for Burn Injuries)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Advertisement

Determining the psychometric properties of a novel questionnaire to measure "preparedness for the future" (Prep FQ).

Daren K Heyland, J Paige Pope, Xuran Jiang, Andrew G Day,

<h4>Background</h4>People are living longer than ever before. However, with living longer comes increased problems that negatively impact on quality of life and the quality of death. Tools are needed to help individuals assess whether they are practicing the best attitudes and behaviors that are associated with a future long life, ... Read more >>

Health Qual Life Outcomes (Health and quality of life outcomes)
[2021, 19(1):122]

Cited: 0 times

View full text PDF listing >>



Application of the modified Nutrition Risk in Critically Ill score to nutritional risk stratification of trauma victims: A multicenter observational study.

Chinenye Iwuchukwu, Grant E O'Keefe, Andrew G Day, Xuran Jiang, Daren K Heyland,

<h4>Background</h4>The modified Nutrition Risk in Critically Ill (mNUTRIC) score was developed to identify patients most likely to benefit from nutritional therapies and to stratify or select study subjects for clinical trials. The score is not validated in trauma victims in whom adequate nutritional support is important and difficult to achieve. ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2020, 89(6):1143-1148]

Cited: 0 times

View full text PDF listing >>



The initial validation of a novel outcome measure in severe burns- the Persistent Organ Dysfunction +Death: Results from a multicenter evaluation.

Christian Stoppe, Aileen Hill, Andrew G Day, Arnold S Kristof, Gabriel Hundeshagen, Ulrich Kneser, Justus Beier, David Lumenta, Bong-Sung Kim, Jan Plock, Declan P Collins, Jochen Gille, Xuran Jiang, Daren K Heyland,

<h4>Introduction</h4>A need exists to improve the efficiency of clinical trials in burn care. The objective of this study was to validate "Persistent Organ Dysfunction" plus death as endpoint in burn patients and to demonstrate its statistical efficiency.<h4>Methods</h4>This secondary outcome analysis of a dataset from a prospective international multicenter RCT (RE-ENERGIZE) ... Read more >>

Burns (Burns : journal of the International Society for Burn Injuries)
[2021, 47(4):765-775]

Cited: 0 times

View full text PDF listing >>



Supporting shared decision-making about cardiopulmonary resuscitation using a video-based decision-support intervention in a hospital setting: a multisite before-after pilot study.

John J You, Dev Jayaraman, Marilyn Swinton, Xuran Jiang, Daren K Heyland,

BACKGROUND:Inpatients are often prescribed cardiopulmonary resuscitation (CPR) without a shared decision-making process. Since implementation of decision aids into practice is highly sensitive to the clinical milieu, we performed a pilot study to refine our study procedures and to evaluate the acceptability and potential effectiveness of a shared decision-making intervention when ... Read more >>

CMAJ Open (CMAJ open)
[2019, 7(4):E630-E637]

Cited: 1 time

View full text PDF listing >>



Short Graphic Values History Tool for decision making during serious illness.

John J You, Peter Allatt, Michelle Howard, Carole A Robinson, Jessica Simon, Rebecca Sudore, Amy Tan, Carrie Bernard, Marilyn Swinton, Xuran Jiang, Doug Klein, Michael McKenzie, Gillian Fyles, Daren Keith Heyland,

<h4>Objectives</h4>To develop and validate a values clarification tool, the Short Graphic Values History Tool (GVHT), designed to support person-centred decision making during serious illness.<h4>Methods</h4>The development phase included input from experts and laypersons and assessed acceptability with patients/family members. In the validation phase, we recruited additional participants into a before-after study. ... Read more >>

BMJ Support Palliat Care (BMJ supportive & palliative care)
[2019, :]

Cited: 1 time

View full text PDF listing >>



Prevention of Nosocomial Infections in Critically Ill Patients With Lactoferrin: A Randomized, Double-Blind, Placebo-Controlled Study.

John Muscedere, David M Maslove, J Gordon Boyd, Nicole O'Callaghan, Stephanie Sibley, Steven Reynolds, Martin Albert, Richard Hall, Xuran Jiang, Andrew G Day, Gwyneth Jones, Francois Lamontagne,

<h4>Objective</h4>To obtain preliminary evidence for the efficacy of lactoferrin as a preventative measure for nosocomial infections and inform the conduct of a definitive study.<h4>Design</h4>Phase 2, multicenter, randomized, double-blind, placebo-controlled study.<h4>Setting</h4>Medical-surgical ICUs.<h4>Patients</h4>Adult, critically ill patients receiving invasive mechanical ventilation.<h4>Interventions</h4>Randomized, eligible, consenting patients expected to require invasive mechanical ventilation more than 48 ... Read more >>

Crit Care Med (Critical care medicine)
[2018, 46(9):1450-1456]

Cited: 3 times

View full text PDF listing >>



Barriers to Goals of Care Discussions With Patients Who Have Advanced Heart Failure: Results of a Multicenter Survey of Hospital-Based Cardiology Clinicians.

John J You, Natasha Aleksova, Anique Ducharme, Jane MacIver, Lisa Mielniczuk, Robert A Fowler, Catherine Demers, Brian Clarke, Marie-Claude Parent, Mustafa Toma, Patricia H Strachan, Paul Farand, Debra Isaac, Shelley Zieroth, Marilyn Swinton, Xuran Jiang, Andrew G Day, Daren K Heyland, Heather J Ross,

<h4>Background</h4>Conversations about goals of care in hospital are important to patients who have advanced heart failure (HF).<h4>Methods</h4>We conducted a multicenter survey of cardiology nurses, fellows, and cardiologists at 8 Canadian teaching hospitals. The primary outcome was the importance of barriers to goals-of-care discussions in hospital (1 = extremely unimportant; 7 = extremely important). We ... Read more >>

J Card Fail (Journal of cardiac failure)
[2017, 23(11):786-793]

Cited: 8 times

View full text PDF listing >>



Validation of quality indicators for end-of-life communication: results of a multicentre survey.

Daren K Heyland, Peter Dodek, John J You, Tasnim Sinuff, Tim Hiebert, Carolyn Tayler, Xuran Jiang, Jessica Simon, James Downar, ,

<h4>Background</h4>The lack of validated quality indicators is a major barrier to improving end-of-life communication and decision-making. We sought to show the feasibility of and provide initial validation for a set of quality indicators related to end-of-life communication and decision-making.<h4>Methods</h4>We administered a questionnaire to patients and their family members in 12 ... Read more >>

CMAJ (CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne)
[2017, 189(30):E980-E989]

Cited: 11 times

View full text PDF listing >>



A randomized trial of supplemental parenteral nutrition in underweight and overweight critically ill patients: the TOP-UP pilot trial.

Paul E Wischmeyer, Michel Hasselmann, Christine Kummerlen, Rosemary Kozar, Demetrios James Kutsogiannis, Constantine J Karvellas, Beth Besecker, David K Evans, Jean-Charles Preiser, Leah Gramlich, Khursheed Jeejeebhoy, Rupinder Dhaliwal, Xuran Jiang, Andrew G Day, Daren K Heyland,

<h4>Background</h4>Nutrition guidelines recommendations differ on the use of parenteral nutrition (PN), and existing clinical trial data are inconclusive. Our recent observational data show that amounts of energy/protein received early in the intensive care unit (ICU) affect patient mortality, particularly for inadequate nutrition intake in patients with body mass indices (BMIs) ... Read more >>

Crit Care (Critical care (London, England))
[2017, 21(1):142]

Cited: 36 times

View full text PDF listing >>



Discordance between patients' stated values and treatment preferences for end-of-life care: results of a multicentre survey.

Daren K Heyland, Rebecca Heyland, Peter Dodek, John J You, Tasnim Sinuff, Tim Hiebert, Xuran Jiang, Andrew G Day, ,

<h4>Background</h4>Medical orders for the use of life-supports should be informed by patients' values and treatment preferences. The purpose of this study was to explore the internal consistency of patients' (or their family members') stated values, and the relationship between these values and expressed preferences.<h4>Methods</h4>We conducted a prospective study in 12 ... Read more >>

BMJ Support Palliat Care (BMJ supportive & palliative care)
[2017, 7(3):292-299]

Cited: 18 times

View full text PDF listing >>



Predicting Performance Status 1 Year After Critical Illness in Patients 80 Years or Older: Development of a Multivariable Clinical Prediction Model.

Daren K Heyland, Henry T Stelfox, Allan Garland, Deborah Cook, Peter Dodek, Jim Kutsogiannis, Xuran Jiang, Alexis F Turgeon, Andrew G Day, ,

<h4>Objective</h4>We sought to develop and internally validate a clinical prediction model to estimate the outcome of very elderly patients 12 months after being admitted to the ICU.<h4>Design</h4>Prospective, longitudinal cohort study.<h4>Setting</h4>Twenty-two Canadian ICUs.<h4>Patients</h4>We recruited 527 patients 80 years or older who had a medical or urgent surgical diagnosis and were admitted ... Read more >>

Crit Care Med (Critical care medicine)
[2016, 44(9):1718-1726]

Cited: 13 times

View full text PDF listing >>



Prevention of nosocomial infections in critically ill patients with lactoferrin (PREVAIL study): study protocol for a randomized controlled trial.

John Muscedere, David Maslove, John Gordon Boyd, Nicole O'Callaghan, Francois Lamontagne, Steven Reynolds, Martin Albert, Rick Hall, Danielle McGolrick, Xuran Jiang, Andrew G Day,

<h4>Background</h4>Nosocomial infections remain an important source of morbidity, mortality, and increased health care costs in hospitalized patients. This is particularly problematic in intensive care units (ICUs) because of increased patient vulnerability due to the underlying severity of illness and increased susceptibility from utilization of invasive therapeutic and monitoring devices. Lactoferrin ... Read more >>

Trials (Trials)
[2016, 17(1):474]

Cited: 1 time

View full text PDF listing >>



Enteral versus parenteral nutrition in critically ill patients: an updated systematic review and meta-analysis of randomized controlled trials.

Gunnar Elke, Arthur R H van Zanten, Margot Lemieux, Michele McCall, Khursheed N Jeejeebhoy, Matthias Kott, Xuran Jiang, Andrew G Day, Daren K Heyland,

<h4>Background</h4>Enteral nutrition (EN) is recommended as the preferred route for early nutrition therapy in critically ill adults over parenteral nutrition (PN). A recent large randomized controlled trial (RCT) showed no outcome differences between the two routes. The objective of this systematic review was to evaluate the effect of the route ... Read more >>

Crit Care (Critical care (London, England))
[2016, 20(1):117]

Cited: 76 times

View full text PDF listing >>



The prevalence of medical error related to end-of-life communication in Canadian hospitals: results of a multicentre observational study.

Daren K Heyland, Roy Ilan, Xuran Jiang, John J You, Peter Dodek,

<h4>Background</h4>In the hospital setting, inadequate engagement between healthcare professionals and seriously ill patients and their families regarding end-of-life decisions is common. This problem may lead to medical orders for life-sustaining treatments that are inconsistent with patient preferences. The prevalence of this patient safety problem has not been previously described.<h4>Methods</h4>Using data ... Read more >>

BMJ Qual Saf (BMJ quality & safety)
[2016, 25(9):671-679]

Cited: 26 times

View full text PDF listing >>



Recovery after critical illness in patients aged 80 years or older: a multi-center prospective observational cohort study.

Daren K Heyland, Allan Garland, Sean M Bagshaw, Deborah Cook, Kenneth Rockwood, Henry T Stelfox, Peter Dodek, Robert A Fowler, Alexis F Turgeon, Karen Burns, John Muscedere, Jim Kutsogiannis, Martin Albert, Sangeeta Mehta, Xuran Jiang, Andrew G Day,

<h4>Purpose</h4>Increasingly, very old patients are admitted to Intensive Care Units (ICUs). The objective of this study was to describe 12-month outcomes of these patients and determine which characteristics are associated with a return to baseline physical function 1 year later.<h4>Methods</h4>In this prospective cohort study in 22 Canadian hospitals, we recruited ... Read more >>

Intensive Care Med (Intensive care medicine)
[2015, 41(11):1911-1920]

Cited: 77 times

View full text PDF listing >>



The Very Elderly Admitted to ICU: A Quality Finish?

Daren Heyland, Deborah Cook, Sean M Bagshaw, Allan Garland, Henry T Stelfox, Sangeeta Mehta, Peter Dodek, Jim Kutsogiannis, Karen Burns, John Muscedere, Alexis F Turgeon, Rob Fowler, Xuran Jiang, Andrew G Day, , ,

<h4>Objective</h4>Very elderly persons admitted to ICUs are at high risk of death. To document life-sustaining interventions (mechanical ventilation, vasopressors, renal replacement therapy) provided in the ICU and outcomes of care.<h4>Design</h4>Multicenter, prospective cohort study.<h4>Setting</h4>ICUs of 24 Canadian hospitals.<h4>Participants/setting</h4>Patients 80 years old or older admitted to the ICU.<h4>Interventions</h4>None.<h4>Measurements and main results</h4>One thousand ... Read more >>

Crit Care Med (Critical care medicine)
[2015, 43(7):1352-1360]

Cited: 56 times

View full text PDF listing >>



Revised Questionnaire to Assess Barriers to Adequate Nutrition in the Critically Ill.

Naomi E Cahill, Xuran Jiang, Daren K Heyland,

<h4>Background</h4>The objective of this study was to revise and improve a questionnaire to assess barriers to providing adequate enteral nutrition (EN) in critically ill adults.<h4>Methods</h4>Changes were made to the questionnaire based on feedback from previous respondents. The revised questionnaire, including 20 potential barriers, was pilot tested in 3 hospitals in ... Read more >>

JPEN J Parenter Enteral Nutr (JPEN. Journal of parenteral and enteral nutrition)
[2016, 40(4):511-518]

Cited: 3 times

View full text PDF listing >>



Evaluation of Persistent Organ Dysfunction Plus Death As a Novel Composite Outcome in Cardiac Surgical Patients.

Christian Stoppe, Bernard McDonald, Carina Benstoem, Gunnar Elke, Patrick Meybohm, Richard Whitlock, Stephen Fremes, Robert Fowler, Yoan Lamarche, Xuran Jiang, Andrew G Day, Daren K Heyland,

<h4>Objectives</h4>Validated composite outcomes after complicated cardiac surgery are poorly established. Therefore, the authors evaluated a novel composite endpoint, persistent organ dysfunction (POD)+death, which is defined as any need for life-sustaining therapies or death at any time within 28 days from surgery.<h4>Design</h4>Secondary analysis extracted from a large-scale prospective randomized trial of ... Read more >>

J Cardiothorac Vasc Anesth (Journal of cardiothoracic and vascular anesthesia)
[2016, 30(1):30-38]

Cited: 9 times

View full text PDF listing >>



What really matters in end-of-life discussions? Perspectives of patients in hospital with serious illness and their families.

John J You, Peter Dodek, Francois Lamontagne, James Downar, Tasnim Sinuff, Xuran Jiang, Andrew G Day, Daren K Heyland, ,

<h4>Background</h4>The guideline-recommended elements to include in discussions about goals of care with patients with serious illness are mostly based on expert opinion. We sought to identify which elements are most important to patients and their families.<h4>Methods</h4>We used a cross-sectional study design involving patients from 9 Canadian hospitals. We asked older ... Read more >>

CMAJ (CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne)
[2014, 186(18):E679-87]

Cited: 44 times

View full text PDF listing >>



Barriers to goals of care discussions with seriously ill hospitalized patients and their families: a multicenter survey of clinicians.

John J You, James Downar, Robert A Fowler, François Lamontagne, Irene W Y Ma, Dev Jayaraman, Jennifer Kryworuchko, Patricia H Strachan, Roy Ilan, Aman P Nijjar, John Neary, John Shik, Kevin Brazil, Amen Patel, Kim Wiebe, Martin Albert, Anita Palepu, Elysée Nouvet, Amanda Roze des Ordons, Nishan Sharma, Amane Abdul-Razzak, Xuran Jiang, Andrew Day, Daren K Heyland, ,

<h4>Importance</h4>Seriously ill hospitalized patients have identified communication and decision making about goals of care as high priorities for quality improvement in end-of-life care. Interventions to improve care are more likely to succeed if tailored to existing barriers.<h4>Objective</h4>To determine, from the perspective of hospital-based clinicians, (1) barriers impeding communication and decision ... Read more >>

JAMA Intern Med (JAMA internal medicine)
[2015, 175(4):549-556]

Cited: 112 times

View full text PDF listing >>



Admission of the very elderly to the intensive care unit: family members' perspectives on clinical decision-making from a multicenter cohort study.

Daren K Heyland, Peter Dodek, Sangeeta Mehta, Deborah Cook, Allan Garland, Henry T Stelfox, Sean M Bagshaw, Demetrios J Kutsogiannis, Karen Burns, John Muscedere, Alexis F Turgeon, Rob Fowler, Xuran Jiang, Andrew G Day, ,

<h4>Background</h4>Little is known about the perspectives and experiences of family members of very elderly patients who are admitted to the intensive care unit.<h4>Aim</h4>To describe family members' perspectives about care provided to very elderly critically ill patients.<h4>Design</h4>Multicenter, prospective, cohort study.<h4>Participants and setting</h4>In total, 535 family members of patients aged 80 years or ... Read more >>

Palliat Med (Palliative medicine)
[2015, 29(4):324-335]

Cited: 29 times

View full text PDF listing >>



Candida in the respiratory tract secretions of critically ill patients and the impact of antifungal treatment: a randomized placebo controlled pilot trial (CANTREAT study).

Martin Albert, David Williamson, John Muscedere, Francois Lauzier, Coleman Rotstein, Salmaan Kanji, Xuran Jiang, Mark Hall, Daren Heyland,

<h4>Purpose</h4>Candida spp. are frequently recovered from endotracheal secretions in critically ill patients suspected of having ventilator-associated pneumonia. Observational studies reported an association with worse clinical outcomes but the effect of antifungal therapy in these patients remains unclear. We designed this pilot study to assess the feasibility of a larger trial ... Read more >>

Intensive Care Med (Intensive care medicine)
[2014, 40(9):1313-1322]

Cited: 21 times

View full text PDF listing >>



Enhanced protein-energy provision via the enteral route feeding protocol in critically ill patients: results of a cluster randomized trial.

Daren K Heyland, Lauren Murch, Naomi Cahill, Michele McCall, John Muscedere, Henry T Stelfox, Tricia Bray, Teddie Tanguay, Xuran Jiang, Andrew G Day,

<h4>Objectives</h4>To determine the effect of the enhanced protein-energy provision via the enteral route feeding protocol, combined with a nursing educational intervention on nutritional intake, compared to usual care.<h4>Design</h4>Prospective, cluster randomized trial.<h4>Setting</h4>Eighteen ICUs from United States and Canada with low baseline nutritional adequacy.<h4>Patients</h4>One thousand fifty-nine mechanically ventilated, critically ill patients.<h4>Interventions</h4>A novel ... Read more >>

Crit Care Med (Critical care medicine)
[2013, 41(12):2743-2753]

Cited: 72 times

View full text PDF listing >>



Advertisement


Disclaimer

1.0226 s