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Author Xueyin Pan


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The miR-455-3p/HDAC2 axis plays a pivotal role in the progression and reversal of liver fibrosis and is regulated by epigenetics.

Hongmei You, Ling Wang, Fangtian Bu, Hongwu Meng, Xueyin Pan, Juanjuan Li, Yafei Zhang, Ao Wang, Nana Yin, Cheng Huang, Jun Li,

Histone deacetylases (HDACs), especially HDAC2, play a role in alleviating liver fibrosis; however, the specific upstream regulation mechanism is unknown. Herein, TargetScan was used to predict the potential upstream targets of HDAC2, and the role of miR-455-3p was explored. The dual luciferase reporter assay showed that miR-455-3p binds to the ... Read more >>

FASEB J (FASEB journal : official publication of the Federation of American Societies for Experimental Biology)
[2021, 35(7):e21700]

Cited: 0 times

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The Long Non-coding RNA MEG3/miR-let-7c-5p Axis Regulates Ethanol-Induced Hepatic Steatosis and Apoptosis by Targeting NLRC5.

Qin Wang, Mingfang Li, Zhiming Shen, Fangtian Bu, Haixia Yu, Xueyin Pan, Yang Yang, Xiaoming Meng, Cheng Huang, Jun Li,

Ethanol (EtOH)-induced hepatic injury, characterized by hepatic steatosis with apoptosis, causes heavy health burden personally and socially. Long non-coding RNAs (lncRNAs) have been implicated in liver diseases. However, the role of lncRNA maternally expressed gene 3 (MEG3) in EtOH-induced hepatic injury remains unknown. The aim of present study was to ... Read more >>

Front Pharmacol (Frontiers in pharmacology)
[2018, 9:302]

Cited: 4 times

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Emerging role of exosomes in liver physiology and pathology.

Shuangpeng Cai, Xiaoyu Cheng, Xueyin Pan, Jun Li,

Exosomes can mediate intercellular communication by conveying various bioactive molecules. Plentiful evidence suggests that exosomes are involved in many liver diseases including hepatitis C virus infection, hepatitis B virus infection, hepatocellular carcinoma, liver fibrosis, cirrhosis, non-alcoholic fatty liver disease, and alcoholic liver disease. Moreover, exosomes are present in nearly all ... Read more >>

Hepatol Res (Hepatology research : the official journal of the Japan Society of Hepatology)
[2017, 47(2):194-203]

Cited: 16 times

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