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Risk factors and clinical outcomes of encapsulating peritoneal sclerosis: A case-control study from China.

Miaoqing Lu, Hongjian Ye, Dongni Chen, Chunyan Yi, Jianxiong Lin, Haiping Mao, Xiao Yang, Xueqing Yu, Wei Chen,

<h4>Background</h4>Encapsulating peritoneal sclerosis (EPS) is an uncommon, but serious complication in patients with continuous ambulatory peritoneal dialysis (PD) who have a considerable mortality rate. This study aimed to identify risk factors and outcomes of EPS in Chinese patients on PD.<h4>Methods</h4>Sixteen patients on PD who met the International Society for Peritoneal ... Read more >>

Perit Dial Int (Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis)
[2021, :8968608211029224]

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Diode laser transscleral cyclophotocoagulation causes intraocular collamer lens displacement in pseudophakic eye: a case report.

Wei Wei, Xueqing Yu, Lu Yang, Chan Xiong, Xu Zhang,

<h4>Background</h4>With the rapid development of intraocular collamer lens (ICL) operation, it is foreseeable that we will encounter a large number of glaucoma patients with ICL implantation history. However, our current understanding of the treatment of glaucoma patients with ICL is limited. Hence we report a rare case of refractory glaucoma ... Read more >>

BMC Ophthalmol (BMC ophthalmology)
[2021, 21(1):268]

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Knowledge-based antibody repertoire simulation, a novel allele detection tool evaluation and application

Xiujia Yang, Yan Zhu, Huikun Zeng, Sen Chen, Junjie Guan, Qilong Wang, Chunhong Lan, Deqiang Sun, Xueqing Yu, Zhenhai Zhang,

Detailed knowledge of the diverse immunoglobulin germline genes is critical for the study of humoral immunity. Hundreds of alleles have been discovered by analyzing antibody repertoire sequencing (Rep-seq or Ig-seq) data via multiple novel allele detection tools (NADTs). However, the performance of these NADTs through antibody sequences with intrinsic somatic ... Read more >>

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Psychological impact and implementation of preventative measures in hemodialysis centers during the COVID-19 pandemic: a provincial questionnaire survey in China.

Yuanhan Chen, Yanhua Wu, Penghua Hu, Xia Fu, Shuangxin Liu, Li Song, Wei Dong, Xueqing Yu, Xinling Liang,

<h4>Objectives</h4>This study investigated the psychological status of patients and staff, and the implementation of preventative measures in hemodialysis centers in Guangdong province, China, during the 2019 novel coronavirus disease (COVID-19) pandemic.<h4>Methods</h4>An electronic questionnaire survey was carried out anonymously between March 28 and April 3, 2020. All of the 516 hemodialysis ... Read more >>

Int Urol Nephrol (International urology and nephrology)
[2021, :]

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Sub-Nanometer Pt Clusters on Defective NiFe LDH Nanosheets as Trifunctional Electrocatalysts for Water Splitting and Rechargeable Hybrid Sodium-Air Batteries.

Xueqing Yu, Junpo Guo, Bo Li, Jincheng Xu, Peng Gao, Kwan San Hui, Kwun Nam Hui, Huaiyu Shao,

It is challenging to develop highly efficient and stable multifunctional electrocatalysts for improving the hydrogen evolution reaction (HER), the oxygen evolution reaction (OER), and the oxygen reduction reaction (ORR) for sustainable energy conversion and storage systems such as water-alkali electrolyzers (WAEs) and hybrid sodium-air batteries (HSABs). In this work, sub-nm ... Read more >>

ACS Appl Mater Interfaces (ACS applied materials & interfaces)
[2021, 13(23):26891-26903]

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Large-scale analysis of 2,152 Ig-seq datasets reveals key features of B cell biology and the antibody repertoire.

Xiujia Yang, Minhui Wang, Jiaqi Wu, Dianchun Shi, Yanfang Zhang, Huikun Zeng, Yan Zhu, Chunhong Lan, Yang Deng, Shixin Guo, Lijun Xu, Cuiyu Ma, Yanxia Zhang, Jinxia Ou, Chu-Jun Liu, Yuan Chen, Qilong Wang, Wenxi Xie, Junjie Guan, Jieyu Ding, Zhi Wang, Changqing Chang, Wei Yang, Huijie Zhang, Jun Chen, Lijie Qin, Hongwei Zhou, Jin-Xin Bei, Lai Wei, Guangwen Cao, Xueqing Yu, Zhenhai Zhang,

Antibody repertoire sequencing enables researchers to acquire millions of B cell receptors and investigate these molecules at the single-nucleotide level. This power and resolution in studying humoral responses have led to its wide applications. However, most of these studies were conducted with a limited number of samples. Given the extraordinary ... Read more >>

Cell Rep (Cell reports)
[2021, 35(6):109110]

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Tackling Dialysis Burden around the World: A Global Challenge.

Philip Kam-Tao Li, Gordon Chun-Kau Chan, Jianghua Chen, Hung-Chun Chen, Yuk-Lun Cheng, Stanley L-S Fan, John Cijiang He, Weixin Hu, Wai-Hon Lim, York Pei, Boon Wee Teo, Ping Zhang, Xueqing Yu, Zhi-Hong Liu,

CKD is a global problem that causes significant burden to the healthcare system and the economy in addition to its impact on morbidity and mortality of patients. Around the world, in both developing and developed economies, the nephrologists and governments face the challenges of the need to provide a quality ... Read more >>

Kidney Dis (Basel) (Kidney diseases (Basel, Switzerland))
[2021, 7(3):167-175]

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Effect of SGLT2 Inhibitors on Stroke and Atrial Fibrillation in Diabetic Kidney Disease: Results From the CREDENCE Trial and Meta-Analysis.

Zien Zhou, Meg J Jardine, Qiang Li, Brendon L Neuen, Christopher P Cannon, Dick de Zeeuw, Robert Edwards, Adeera Levin, Kenneth W Mahaffey, Vlado Perkovic, Bruce Neal, Richard I Lindley, ,

<h4>Background and purpose</h4>Chronic kidney disease with reduced estimated glomerular filtration rate or elevated albuminuria increases risk for ischemic and hemorrhagic stroke. This study assessed the effects of sodium glucose cotransporter 2 inhibitors (SGLT2i) on stroke and atrial fibrillation/flutter (AF/AFL) from CREDENCE (Canagliflozin and Renal Events in Diabetes With Established Nephropathy ... Read more >>

Stroke (Stroke)
[2021, 52(5):1545-1556]

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Inflammatory stress in SARS-COV-2 associated Acute Kidney Injury.

Junzhe Chen, Wenbiao Wang, Ying Tang, Xiao-Ru Huang, Xueqing Yu, Hui-Yao Lan,

Increasing clinical evidence shows that acute kidney injury (AKI) is a common and severe complication in critically ill COVID-19 patients. The older age, the severity of COVID-19 infection, the ethnicity, and the history of smoking, diabetes, hypertension, and cardiovascular disease are the risk factor for AKI in COVID-19 patients. Of ... Read more >>

Int J Biol Sci (International journal of biological sciences)
[2021, 17(6):1497-1506]

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Anemia Management in Peritoneal Dialysis: Perspectives From the Asia Pacific Region.

Philip Kam Tao Li, Agnes Shin Man Choy, Sunita Bavanandan, Wei Chen, Marjorie Foo, Talerngsak Kanjanabuch, Yong-Lim Kim, Masaaki Nakayama, Xueqing Yu,

Anemia is an important complication in patients with chronic kidney disease. Peritoneal dialysis (PD) is one of the most common modalities of kidney replacement therapy for patients with end-stage kidney disease. PD is particularly prevalent in the Asian Pacific region. Among the different countries and regions, including mainland China, Hong ... Read more >>

Kidney Med (Kidney medicine)
[2021, 3(3):405-411]

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Prognostic significance of hypertension at the onset of lupus nephritis in Chinese patients: prevalence and clinical outcomes.

Rong Rong, Qiong Wen, Yating Wang, Qian Zhou, Yagui Qiu, Miaoqing Lu, Xiaotian Liu, Wei Chen, Xueqing Yu,

The demographic features, and clinical and histological characteristics of lupus nephritis (LN) patients with hypertension in the Chinese population remain unclear. Hence, the clinical characteristics of LN with and without hypertension were retrospectively analyzed. A total of 764 LN patients (53.1%) were hypertensive. These hypertensive patients had higher levels of ... Read more >>

J Hum Hypertens (Journal of human hypertension)
[2021, :]

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Procalcitonin-guided antibiotic therapy in AECOPD patients: Overview of systematic reviews.

Jiaqi Di, Xuanlin Li, Yang Xie, Shuguang Yang, Xueqing Yu,

<h4>Background</h4>Procalcitonin (PCT)-guided antibiotic therapy has emerged as mainstream treatment for acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and has been studied in many systematic reviews (SRs), but robust conclusion has not been drawn. Thus, this overview aims to summarize and critically evaluate the methodological and evidence quality of SRs ... Read more >>

Clin Respir J (The clinical respiratory journal)
[2021, 15(6):579-594]

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Prevalence, risk factors and impact on outcomes of 30-day unexpected rehospitalization in incident peritoneal dialysis patients.

Jianbo Li, Jing Yu, Naya Huang, Hongjian Ye, Dan Wang, Yuan Peng, Xiaobo Guo, Chunyan Yi, Xiao Yang, Xueqing Yu,

<h4>Background</h4>Rehospitalization is a major problem for end stage renal disease (ESRD) populations. However, researches on 30-day unexpected rehospitalzation of incident peritoneal dialysis (PD) patients were limited. This study aimed to investigate the prevalence, risk factors and impact on outcomes of 30-day unexpected rehospitalization in incident PD patients.<h4>Methods</h4>This was a retrospective ... Read more >>

BMC Nephrol (BMC nephrology)
[2021, 22(1):4]

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Epigenome-wide association study and network analysis for IgA Nephropathy from CD19+ B-cell in Chinese Population.

Yifei Lin, Peiran Yin, Zhaozhong Zhu, Yuan Peng, Ming Li, Jun Li, Liming Liang, Xueqing Yu,

IgA nephropathy (IgAN) is the most common primary glomerular disease in China and worldwide. The proliferation of B cells is known to be associated with both risk and prognosis of IgAN, but the epigenetic mechanism underlying this association is unknown. In this study we carried out the first Epigenome-wide Association ... Read more >>

Epigenetics (Epigenetics)
[2021, :1-12]

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Utility of radium quartet for evaluating porewater-derived carbon to a saltmarsh nearshore water: Implications for blue carbon export.

Jianan Liu, Xueqing Yu, Xiaogang Chen, Jinzhou Du, Fenfen Zhang,

Saltmarshes are global hotspots of carbon sequestration and storage and are known as effective blue carbon ecosystems. However, the role of porewater exchange in saltmarshes as a source of carbon to the nearshore waters is still poorly constrained. Herein, we examined the radium quartet, dissolved inorganic (DIC) and organic (DOC) ... Read more >>

Sci Total Environ (The Science of the total environment)
[2021, 764:144238]

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Long-term renal outcomes of IgA nephropathy presenting with different levels of proteinuria.

Zhen Ai, Qian Zhou, Fengxian Huang, Qiongqiong Yang, Xueqing Yu,

<h4>Aims</h4>Proteinuria is a strong prognostic factor in IgA nephropathy (IgAN). However, the risk threshold of proteinuria for kidney disease progression remains in debate. This study aimed to evaluate the risk of different levels of proteinuria on renal outcomes in Chinese patients with IgAN.<h4>Materials and methods</h4>Patients with biopsy-proven primary IgAN were ... Read more >>

Clin Nephrol (Clinical nephrology)
[2020, 94(6):290-296]

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Early initiation of PD therapy in elderly patients is associated with increased risk of death.

Yuan Peng, Hongjian Ye, Chunyan Yi, Xi Xiao, Xuan Huang, Ruihua Liu, Xiangwen Diao, Haiping Mao, Xueqing Yu, Xiao Yang,

<h4>Background</h4>The effect of early initiation of dialysis on outcomes of patients with end-stage renal disease (ESRD) remains controversial. We conducted this study to investigate the association between the timing of peritoneal dialysis (PD) initiation and mortality in different age groups.<h4>Methods</h4>In this single-centre cohort study, incident patients receiving PD from 1 ... Read more >>

Clin Kidney J (Clinical kidney journal)
[2021, 14(6):1649-1656]

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The Association between Serum Uric Acid and Appendicular Skeletal Muscle Mass and the Effect of Their Interaction on Mortality in Patients on Peritoneal Dialysis.

Xi Xiao, Chunyan Yi, Yuan Peng, Hongjian Ye, Haishan Wu, Meiju Wu, Xuan Huang, Xueqing Yu, Xiao Yang,

<h4>Background</h4>Serum uric acid (SUA) has been revealed to be positively associated with the body composition parameters in hemodialysis patients, but few studies have investigated that in patients on peritoneal dialysis (PD). The aim of this study was to identify the relationship between SUA and appendicular skeletal muscle mass (ASM) and ... Read more >>

Kidney Blood Press Res (Kidney & blood pressure research)
[2020, 45(6):969-981]

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Critical appraisal of the quality of clinical practice guidelines for idiopathic pulmonary fibrosis.

Xuanlin Li, Xueqing Yu, Yang Xie, Zhenzhen Feng, Yanfang Ma, Yaolong Chen, Jiansheng Li,

<h4>Background</h4>Clinical practice guidelines (CPGs) have long served as an essential tool for clinicians to rationalize their treatment in practice. However, the quality of guidelines varies greatly. The present study aimed to analyze high-quality CPGs of idiopathic pulmonary fibrosis (IPF) and highlight the potential for further improvement.<h4>Methods</h4>Three guideline developers' websites, PubMed, ... Read more >>

Ann Transl Med (Annals of translational medicine)
[2020, 8(21):1405]

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Infection-related hospitalization after intensive immunosuppressive therapy among lupus nephritis and ANCA glomerulonephritis patients.

Peihong Yin, Jianbo Li, Qiong Wen, Yagui Qiu, Wenyi Liang, Junxian Wang, Jing Yu, Zhong Zhong, Xiao Yang, Xueqing Yu, Qing Ye, Fengxian Huang,

<b>Introduction:</b> This study aimed to investigate the clinical characteristics, risk factors, and outcomes of infection-related hospitalization (IRH) in patients with lupus nephritis (LN) and ANCA glomerulonephritis after intensive immunosuppressive therapy.<b>Methods:</b> Patients diagnosed with LN or ANCA glomerulonephritis who received intensive immunosuppressive therapy at the First Affiliated Hospital of Sun Yat-sen ... Read more >>

Ren Fail (Renal failure)
[2020, 42(1):474-482]

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Uric acid to high-density lipoprotein cholesterol ratio predicts cardiovascular mortality in patients on peritoneal dialysis.

Ruihua Liu, Yuan Peng, Haishan Wu, Xiangwen Diao, Hongjian Ye, Xuan Huang, Chunyan Yi, Haiping Mao, Fengxian Huang, Xueqing Yu, Xiao Yang,

<h4>Background and aims</h4>Serum uric acid (UA) and high-density lipoprotein cholesterol (HDL-C) disorders are both considered as risk factors of cardiovascular mortality. The predictive value of UA to HDL-C ratio (UHR) has been validated in diabetes. However, association of UHR with cardiovascular (CV) mortality is undetermined in peritoneal dialysis (PD) patients.<h4>Methods ... Read more >>

Nutr Metab Cardiovasc Dis (Nutrition, metabolism, and cardiovascular diseases : NMCD)
[2021, 31(2):561-569]

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Extracellular Vesicles From High Glucose-Treated Podocytes Induce Apoptosis of Proximal Tubular Epithelial Cells.

Ying Huang, Ruizhao Li, Li Zhang, Yuanhan Chen, Wei Dong, Xingchen Zhao, Huan Yang, Shu Zhang, Zhiyong Xie, Zhiming Ye, Weidong Wang, Chunling Li, Zhilian Li, Shuangxin Liu, Zheng Dong, Xueqing Yu, Xinling Liang,

Diabetic kidney disease (DKD) is a serious and common complication of diabetes. Extracellular vesicles (EVs) have emerged as crucial vectors in cell-to-cell communication during the development of DKD. EVs may mediate intercellular communication between podocytes and proximal tubules. In this study, EVs were isolated from podocyte culture supernatants under high ... Read more >>

Front Physiol (Frontiers in physiology)
[2020, 11:579296]

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Rationale and design for Lowering-hyperUricaemia treatment on cardiovascular outcoMes In peritoNeal diAlysis patients: a prospective, multicentre, double-blind, randomised controlled trial (LUMINA).

Wei Chen, Naya Huang, Haiping Mao, Xiao Yang, Qian Zhou, Lanping Jiang, Jun Ding, Qiong Feng, Xueqing Yu,

<h4>Introduction</h4>The prevalence of hyperuricaemia in peritoneal dialysis patients is quite high. Studies have demonstrated a correlation between hyperuricaemia and cardiovascular disease and treatment of hyperuricaemia reportedly reduces cardiovascular risk in patients with chronic kidney disease. However, whether hyperuricaemia treatment benefits cardiovascular outcomes in continuous ambulatory peritoneal dialysis (CAPD) patients is ... Read more >>

BMJ Open (BMJ open)
[2020, 10(10):e037842]

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Two-Year, Randomized, Controlled Trial of Belimumab in Lupus Nephritis.

Richard Furie, Brad H Rovin, Frédéric Houssiau, Ana Malvar, Y K Onno Teng, Gabriel Contreras, Zahir Amoura, Xueqing Yu, Chi-Chiu Mok, Mittermayer B Santiago, Amit Saxena, Yulia Green, Beulah Ji, Christi Kleoudis, Susan W Burriss, Carly Barnett, David A Roth,

<h4>Background</h4>In adults with active lupus nephritis, the efficacy and safety of intravenous belimumab as compared with placebo, when added to standard therapy (mycophenolate mofetil or cyclophosphamide-azathioprine), are unknown.<h4>Methods</h4>In a phase 3, multinational, multicenter, randomized, double-blind, placebo-controlled, 104-week trial conducted at 107 sites in 21 countries, we assigned adults with biopsy-proven, ... Read more >>

N Engl J Med (The New England journal of medicine)
[2020, 383(12):1117-1128]

Cited: 26 times

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Associations of Ganglion Cell-Inner Plexiform Layer and Optic Nerve Head Parameters with Visual Field Sensitivity in Advanced Glaucoma.

Haijian Hu, Ping Li, Xueqing Yu, Wei Wei, Hai He, Xu Zhang,

<h4>Purpose</h4>To evaluate the associations of optical coherence tomography (OCT)-derived macular ganglion cell-inner plexiform layer thickness (mGCIPLT), circumpapillary retinal nerve fiber layer thickness (cpRNFLT), and optic nerve head (ONH) parameters with visual field (VF) sensitivity in advanced glaucoma.<h4>Methods</h4>In this cross-sectional study, 102 eyes from 102 patients with advanced glaucoma (defined as ... Read more >>

Ophthalmic Res (Ophthalmic research)
[2021, 64(2):310-320]

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