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Publisher Correction: A mass spectrometry-based proteome map of drug action in lung cancer cell lines.

Benjamin Ruprecht, Julie Di Bernardo, Zhao Wang, Xuan Mo, Oleg Ursu, Matthew Christopher, Rafael B Fernandez, Li Zheng, Brian D Dill, Huijun Wang, Yuting Xu, Andy Liaw, Jonathan D Mortison, Nirodhini Siriwardana, Brian Andresen, Meir Glick, James R Tata, Victoria Kutilek, Ivan Cornella-Taracido, An Chi,

An amendment to this paper has been published and can be accessed via a link at the top of the paper. ... Read more >>

Nat Chem Biol (Nature chemical biology)
[2020, 16(10):1149]

Cited: 0 times

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A mass spectrometry-based proteome map of drug action in lung cancer cell lines.

Benjamin Ruprecht, Julie Di Bernardo, Zhao Wang, Xuan Mo, Oleg Ursu, Matthew Christopher, Rafael B Fernandez, Li Zheng, Brian D Dill, Huijun Wang, Yuting Xu, Andy Liaw, Jonathan D Mortison, Nirodhini Siriwardana, Brian Andresen, Meir Glick, James R Tata, Victoria Kutilek, Ivan Cornella-Taracido, An Chi,

Mass spectrometry-based discovery proteomics is an essential tool for the proximal readout of cellular drug action. Here, we apply a robust proteomic workflow to rapidly profile the proteomes of five lung cancer cell lines in response to more than 50 drugs. Integration of millions of quantitative protein-drug associations substantially improved ... Read more >>

Nat. Chem. Biol. (Nature chemical biology)
[2020, 16(10):1111-1119]

Cited: 0 times

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Macroenvironment-gene-microenvironment interactions in ultraviolet radiation-induced melanomagenesis.

Xuan Mo, Sarah Preston, M Raza Zaidi,

Cutaneous malignant melanoma is one of the few major cancers that continue to exhibit a positive rate of increase in the developed world. A wealth of epidemiological data has undisputedly implicated ultraviolet radiation (UVR) from sunlight and artificial sources as the major risk factor for melanomagenesis. However, the molecular mechanisms ... Read more >>

Adv. Cancer Res. (Advances in cancer research)
[2019, 144:1-54]

Cited: 1 time

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Interferon-γ Signaling in Melanocytes and Melanoma Cells Regulates Expression of CTLA-4.

Xuan Mo, Hanghang Zhang, Sarah Preston, Kayla Martin, Bo Zhou, Nish Vadalia, Ana M Gamero, Jonathan Soboloff, Italo Tempera, M Raza Zaidi,

CTLA4 is a cell surface receptor on T cells that functions as an immune checkpoint molecule to enforce tolerance to cognate antigens. Anti-CTLA4 immunotherapy is highly effective at reactivating T-cell responses against melanoma, which is postulated to be due to targeting CTLA4 on T cells. Here, we report that CTLA4 ... Read more >>

Cancer Res (Cancer research)
[2018, 78(2):436-450]

Cited: 20 times

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Direct determination of underivatized amino acids from Ginkgo biloba leaves by using hydrophilic interaction ultra high performance liquid chromatography coupled with triple quadrupole mass spectrometry.

Xin Yao, Guisheng Zhou, Yuping Tang, Hanqing Pang, Yefei Qian, Sheng Guo, Xuan Mo, Shaoqing Zhu, Shulan Su, Dawei Qian, Chun Jin, Yong Qin, Jin-ao Duan,

Ginkgo biloba leaf extract has been widely used in dietary supplements and more recently in some foods and beverages. In addition to the well-known flavonol glycosides and terpene lactones, G. biloba leaves are also rich in amino acids. To determine the content of free amino acids, a reliable method has ... Read more >>

J Sep Sci (Journal of separation science)
[2013, 36(17):2878-2887]

Cited: 9 times

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FADD is essential for glucose uptake and survival of thymocytes.

Xiang-Yu Zhang, Bing-Ya Yang, Jia-Yu Wang, Xuan Mo, Jing Zhang, Zi-Chun Hua,

Fas-associated protein with death domain (FADD) has been implicated in T lymphocytes, but the nature of FADD-dependent mechanism in early T cell development has not been completely elucidated. In this study, using T-cell specific deletion mice, we observed that FADD deficiency in thymocytes led to increased apoptosis and reduced cell ... Read more >>

Biochem. Biophys. Res. Commun. (Biochemical and biophysical research communications)
[2014, 451(2):202-207]

Cited: 3 times

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Analysis of herb-herb interaction when decocting together by using ultra-high-performance liquid chromatography-tandem mass spectrometry and fuzzy chemical identification strategy with poly-proportion design.

Juan Shen, Xuan Mo, Yuping Tang, Li Zhang, Hanqing Pang, Yefei Qian, Yanyan Chen, Weiwei Tao, Sheng Guo, Erxin Shang, Shaoqing Zhu, Yunhe Ding, Jianming Guo, Pei Liu, Shulan Su, Dawei Qian, Jin-ao Duan,

A novel and generally applicable approach was established for the herb-herb interaction analysis when decocting together by using ultra-high-performance liquid chromatography coupled with a triple quadrupole electrospray tandem mass spectrometer and fuzzy chemical identification with poly-proportion design. A simple programme was originally developed for the rapid identification and classification of ... Read more >>

J Chromatogr A (Journal of chromatography. A)
[2013, 1297:168-178]

Cited: 23 times

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Two new nonacosanetriols from Ginkgo biloba sarcotesta.

Guisheng Zhou, Xin Yao, Yuping Tang, Nianyun Yang, Hanqing Pang, Xuan Mo, Shaoqing Zhu, Shulan Su, Dawei Qian, Chun Jin, Yong Qin, Jin-ao Duan,

Two new fatty alcohols named as (7S,8R,11S)-nonacosanetriol (1) and (10R,12R,15S)-nonacosanetriol (2), along with eight known compounds including ginkgolic acid (3), hydroginkgolic acid (4), sciadopitysin (5), ginkgetin (6), isoginkgetin (7), ginkgolide A (8), ginkgolide B (9) and ginkgolide C (10) have been isolated from the petroleum ether extract of Ginkgo biloba ... Read more >>

Chem Phys Lipids (Chemistry and physics of lipids)
[2012, 165(7):731-736]

Cited: 2 times

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Hydrophilic interaction ultra-performance liquid chromatography coupled with triple-quadrupole tandem mass spectrometry for highly rapid and sensitive analysis of underivatized amino acids in functional foods.

Guisheng Zhou, Hanqing Pang, Yuping Tang, Xin Yao, Xuan Mo, Shaoqing Zhu, Sheng Guo, Dawei Qian, Yefei Qian, Shulan Su, Li Zhang, Chun Jin, Yong Qin, Jin-ao Duan,

This work presented a new analytical methodology based on hydrophilic interaction ultra-performance liquid chromatography coupled with triple-quadrupole tandem mass spectrometry in multiple-reaction monitoring mode for analysis of 24 underivatized free amino acids (FAAs) in functional foods. The proposed method was first reported and validated by assessing the matrix effects, linearity, ... Read more >>

Amino Acids (Amino acids)
[2013, 44(5):1293-1305]

Cited: 21 times

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Design and optimization of color lookup tables on a simplex topology.

Vishal Monga, Raja Bala, Xuan Mo,

An important computational problem in color imaging is the design of color transforms that map color between devices or from a device-dependent space (e.g., RGB/CMYK) to a device-independent space (e.g., CIELAB) and vice versa. Real-time processing constraints entail that such nonlinear color transforms be implemented using multidimensional lookup tables (LUTs). ... Read more >>

IEEE Trans Image Process (IEEE transactions on image processing : a publication of the IEEE Signal Processing Society)
[2012, 21(4):1981-1996]

Cited: 1 time

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