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A best-worst scaling survey of medical students' perspective on implementing shared decision-making in China.

Richard Huan Xu, Lingming Zhou, Eliza Lai-Yi Wong, Dong Wang, Guo Chun Xiang, Chao Xu,

<h4>Background</h4>The objective of this study was to ascertain the importance rankings of factors affecting the implementation of shared decision-making (SDM) in medical students in China and determine whether these factors were consistent across the respondents' individual characteristics.<h4>Method</h4>Students studying clinical medicine were recruited from three medical universities in China. A cross-sectional ... Read more >>

BMC Med Educ (BMC medical education)
[2020, 20(1):486]

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Long-term effects of biochar on trace metals accumulation in rice grain: A 7-year field experiment

Shuai Wang, Bo Li, Hanhua Zhu, Jianlin Shen, Qihong Zhu, Daoyou Huang, Chao Xu, Quan Zhang, Zebo Fang,

Biochar (BC) is an emerging amendment for minimizing the phytoavailability of trace metals in soil-crop system, but its relevant durability and mechanism are unclear. A 7-year field study was conducted in double rice paddy land of mid-subtropical China. Wheat straw BC was once applied at rates of 24 and 48 ... Read more >>

(Agriculture, ecosystems & environment.)
[2021, 315:Not Available]

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Co-fermentation of succinic acid and ethanol from sugarcane bagasse based on full hexose and pentose utilization and carbon dioxide reduction.

Chao Xu, Md Asraful Alam, Zhongming Wang, Yuande Peng, Chunliang Xie, Wenbing Gong, Qi Yang, Shushi Huang, Wei Zhuang, Jingliang Xu,

The full utilization of carbohydrates in lignocellulosic biomass is essential for an efficient biorefining process. In this study, co-fermentation was performed for processing ethanol and succinic from sugarcane bagasse. By optimizing the co-fermentation conditions, nutrition and feeding strategies, a novel process was developed to make full utilization of the glucose ... Read more >>

Bioresour Technol (Bioresource technology)
[2021, 339:125578]

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Accumulation and Distribution of Fluorescent Microplastics in the Early Life Stages of Zebrafish.

Chao Xu, Hangqin Guo, Ruijiong Wang, Tianyang Li, Linqi Gu, Liwei Sun,

As a new type of environmental pollutant, microplastic has been widely found in the aquatic environment and poses a high threat to aquatic organisms. The bioaccumulation of microplastics plays a key role in their toxic effects; however, as a particulate, their bioaccumulations are different from many other pollutants. Described here ... Read more >>

J Vis Exp (Journal of visualized experiments : JoVE)
[2021, (173):]

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The Impact of Adherence to Disease-Modifying Therapies on Functional Outcomes in Veterans with Multiple Sclerosis.

Meheroz H Rabadi, Kimberly Just, Chao Xu,

<h4>Background</h4>Patients who adhere to their DMTs have lower rate of MS-related relapses and disability.<h4>Objective</h4>We sought to determine the adherence rate to disease-modifying therapies (DMTs) and its impact on functional outcome(s) in veterans with multiple sclerosis (MS).<h4>Method</h4>We reviewed the electronic records of 279 veterans with MS who were periodically followed in ... Read more >>

J Cent Nerv Syst Dis (Journal of central nervous system disease)
[2021, 13:11795735211028769]

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InSe/Te van der Waals Heterostructure as a High-Efficiency Solar Cell from Computational Screening.

Zechen Ma, Ruifeng Li, Rui Xiong, Yinggan Zhang, Chao Xu, Cuilian Wen, Baisheng Sa,

Designing the electronic structures of the van der Waals (vdW) heterostructures to obtain high-efficiency solar cells showed a fascinating prospect. In this work, we screened the potential of vdW heterostructures for solar cell application by combining the group III-VI MX<sub>A</sub> (M = Al, Ga, In and X<sub>A</sub> = S, Se, ... Read more >>

Materials (Basel) (Materials (Basel, Switzerland))
[2021, 14(14):]

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A New Multi-objective Comprehensive Optimization Model for Design of Anti-slide Piles

Chao Xu, Lei Xue, Yuan Cui, Songfeng Guo, Mengyang Zhai, Fengchang Bu, Haoyu Wang,

Landslides have posed a huge threat to the ecological environment and human society all over the world. As the most conventional reinforcement method, anti-slide piles are widely used in the reinforcement of slopes. Currently, more and more attentions have been paid to the low-cost and high-efficiency optimal design of anti-slide ... Read more >>

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17β-oestradiol alleviates endoplasmic reticulum stress injury induced by chronic cerebral hypoperfusion through the Haemoglobin/HIF 1α signalling pathway in ovariectomized rats.

Chao Xu, Yongxin Dai, Jing Bai, Bo Ren, Jing Xu, Fujia Gao, Lu Wang, Wenli Zhang, Ruimin Wang,

Endoplasmic reticulum stress (ERS) is known to be an essential target in protecting against ischaemic brain injury. In this study, using a vascular dementia (VaD) animal model induced by bilateral common carotid artery occlusion (BCCAO), we evaluated the effect and mechanism of 17β-oestradiol (E2) against VaD by inhibiting ERS at ... Read more >>

Neurochem Int (Neurochemistry international)
[2021, 148:105119]

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Downregulated lncRNA RCPCD promotes differentiation of embryonic stem cells into cardiac pacemaker-like cells by suppressing HCN4 promoter methylation.

Ye Zhu, Jia You, Wei Wei, Jianjun Gu, Chao Xu, Xiang Gu,

Long non-coding RNA (lncRNA) is receiving increasing attention in embryonic stem cells (ESCs) research. However, the roles of lncRNA in the differentiation of ESCs into pacemaker-like cells are still unclear. Therefore, the present study aims to explore the roles and mechanisms of lncRNA in the differentiation of ESCs into pacemaker-like ... Read more >>

Cell Death Dis (Cell death & disease)
[2021, 12(7):667]

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Benfotiamine ameliorates high‐carbohydrate diet‐induced hepatic oxidative stress, inflammation and apoptosis in Megalobrama amblycephala

Chao Xu, Wen‐Bin Liu, Hua‐Juan Shi, Hai‐Feng Mi, Xiang‐Fei Li,

A 12‐week nutritional research was conducted to evaluate the influences of benfotiamine on the growth performance, oxidative stress, inflammation and apoptosis in Megalobrama amblycephala (45.25 ± 0.34 g) fed high‐carbohydrate (HC) diets. Six diets were prepared, containing the control diet (30% carbohydrate, C), the HC diet (43% carbohydrate) and the HC diet supplemented ... Read more >>

Aquac Res (Aquaculture research.)
[2021, 52(7):3174-3185]

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InSe/Te van der Waals Heterostructure as a High-Efficiency Solar Cell from Computational Screening

Zechen Ma, Ruifeng Li, Rui Xiong, Yinggan Zhang, Chao Xu, Cuilian Wen, Baisheng Sa,

Designing the electronic structures of the van der Waals (vdW) heterostructures to obtain high-efficiency solar cells showed a fascinating prospect. In this work, we screened the potential of vdW heterostructures for solar cell application by combining the group III–VI MXA (M = Al, Ga, In and XA = S, Se, ... Read more >>

Materials (Basel) (Materials (Basel, Switzerland))
[2021, 14(14):]

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[Effect of Ozone Dosage on Sludge Settleability and Biological Nutrient Removal in SBR System].

Yong-Tao Lü, Chuan-Shou Zhu, Xu-Yang Zhang, Chao Xu, Yong-Bao Pan, Shuang Liu, Shuang-Ke Cui, Lei Wang,

The effect of ozone dosage on sludge settleability and biological nutrient removal performance in a sequencing batch reactor was investigated by inoculating the bulking sludge with the SVI of 280 mL·g<sup>-1</sup> from a wastewater treatment plant in winter. The filamentous mycelium was interrupted, and the SVI was decreased to 125 ... Read more >>

Huan Jing Ke Xue (Huan jing ke xue= Huanjing kexue)
[2021, 42(7):3400-3404]

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Study on the influence of composite soil on the slope stability of farmland during in land consolidation

Chuan Zhang, Wujiang Liu, Xiaoshun Li, Song Yang, Chao Xu, Yuexiang Wang, Qingsong Duan, Honggang Zheng,

To improve the stability of sloping farmland, the optimal ratio parameter of composite soil was determined. Single and mixed composite soils were prepared with three improved materials of glutinous rice glue, wood fibres and coarse sand for indoor direct shear tests and pot experiments. Based on the different moisture and ... Read more >>

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Construction of a Prognostic Nomogram for Colorectal Cancer Patients with Fewer than Twelve Lymph Nodes Examined: a Population-Based Study in the SEER Database and China.

Hao Zhang, Hanqing Hu, Zilong Guan, Rui Chen, Chao Xu, Rui Huang, Guiyu Wang,

J Gastrointest Surg (Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract)
[2021, :]

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Platelet Rich Plasma-Derived Exosomal USP15 Promotes Cutaneous Wound Healing via Deubiquitinating EIF4A1

Yan Xu, Ze Lin, Lei He, Yanzhen Qu, Ouyang Liu, Yu Han, Chao Xu, Deyu Duan,

<h4>Background: </h4> Epithelial regeneration is an essential wound healing process, and recent work suggests that different types of exosomes (Exos) can be employed to improve wound repair outcomes by promoting such epithelial regeneration. Platelet-rich plasma (PRP) is known to facilitate enhanced wound healing, yet the mechanisms underlying its activity are ... Read more >>

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Left Atrial Appendage Morphology and Local Thrombogenesis-Related Blood Parameters in Patients With Atrial Fibrillation.

Buyun Xu, Ye Du, Chao Xu, Yong Sun, Fang Peng, Shengkai Wang, Jie Pan, Yuanqing Lou, Yangbo Xing,

Background Left atrial appendage (LAA) morphology predicts stroke risk in patients with atrial fibrillation. However, it is not precisely understood how LAA morphology influences stroke risk. The present study aimed to investigate the relationship between LAA morphology and local thrombogenesis-related blood parameters in LAA. Methods and Results We enrolled 205 ... Read more >>

J Am Heart Assoc (Journal of the American Heart Association)
[2021, 10(12):e020406]

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Two-dimensional ferroelasticity in van der Waals β'-In2Se3.

Chao Xu, Jianfeng Mao, Xuyun Guo, Shanru Yan, Yancong Chen, Tsz Wing Lo, Changsheng Chen, Dangyuan Lei, Xin Luo, Jianhua Hao, Changxi Zheng, Ye Zhu,

Two-dimensional (2D) materials exhibit remarkable mechanical properties, enabling their applications as flexible and stretchable ultrathin devices. As the origin of several extraordinary mechanical behaviors, ferroelasticity has also been predicted theoretically in 2D materials, but so far lacks experimental validation and investigation. Here, we present the experimental demonstration of 2D ferroelasticity ... Read more >>

Nat Commun (Nature communications)
[2021, 12(1):3665]

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Identification of Novel Biomarkers in Hepatocellular Carcinoma by Integrated Bioinformatical Analysis and Experimental Validation

Chen Liao, Lanlan Wang, Xiaoqiang Li, Jinyu Bai, Jieqiong Wu, Wei Zhang, Hailong Shi, Xuesong Feng, Xu Chao,

<h4>Background: </h4> Hepatocellular carcinoma (HCC) is one of the most common poorly prognosed virulent neoplasms of the digestive system. In this study, we identified novel biomarkers associated with the pathogenesis of HCC aiming to provide new diagnostic and therapeutic approaches for HCC. <h4>Methods: </h4>: Gene expression profiles of GSE62232, GSE84402,GSE121248 ... Read more >>

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MEMS-Based Electrochemical Seismometer with a Sensing Unit Integrating Four Electrodes.

Wenjie Qi, Chao Xu, Bowen Liu, Xu She, Tian Liang, Deyong Chen, Junbo Wang, Jian Chen,

This paper presents a new process to fabricate a sensing unit of electrochemical seismometers using only one silicon-glass-silicon bonded wafer. By integrating four electrodes on one silicon-glass-silicon bonded wafer, the consistency of the developed sensing unit was greatly improved, benefiting from the high alignment accuracy. Parameter designs and simulations were ... Read more >>

Micromachines (Basel) (Micromachines)
[2021, 12(6):]

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Criteria for Emergency Brain MRI During Stroke-Alert.

Evgeny Sidorov, Courtney Iser, Nidhi Kapoor, Bappaditya Ray, Juliane Chainakul, Chao Xu, Andrei V Alexandrov, David Lee Gordon,

<h4>Objectives</h4>Intravenous (IV) tissue plasminogen activator (tPA) should be given to patients with acute ischemic stroke (AIS) and avoided in stroke mimics (SM). Select use of emergency brain magnetic resonance imaging (eMRI-brain) in stroke-alerts aids diagnosis, but accepted utilization criteria for eMRI-brain do not currently exist. We developed criteria for eMRI-brain ... Read more >>

J Stroke Cerebrovasc Dis (Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association)
[2021, 30(8):105890]

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Influence of a N-Heterocyclic Core on the Binding Capability of N,O-Hybrid Diamide Ligands toward Trivalent Lanthanides and Actinides.

Ruixue Meng, Lei Xu, Xiao Yang, Mingze Sun, Chao Xu, Nataliya E Borisova, Xingwang Zhang, Lecheng Lei, Chengliang Xiao,

N,O-hybrid diamide ligands with N-heterocyclic skeletons are one of the promising extractants for the selective separation of actinides over lanthanides in a highly acidic HNO<sub>3</sub> solution. In this work, three hard-soft donor mixed diamide ligands, pyridine-2,6-diylbis(pyrrolidin-1-ylmethanone) (Pyr-PyDA), 2,2'-bipyridine-6,6'-diylbis(pyr-rolidine-1-ylmethanone) (Pyr-BPyDA), and (1,10-phenanthroline-2,9-diyl)bis(pyrrolidin-1-ylmethanone) (Pyr-DAPhen), were synthesized and used to probe the influence ... Read more >>

Inorg Chem (Inorganic chemistry)
[2021, 60(12):8754-8764]

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Nanostructure-Mediated Phase Evolution in Lithiation/Delithiation of Co3O4.

Yu Fu, Xuyun Guo, Zhenglong Xu, Guangming Zhao, Chao Xu, Ye Zhu, Limin Zhou,

Nanostructured transition-metal oxides have been under intensive investigation for their tantalizing potential as anodes of next-generation lithium-ion batteries (LIBs). However, the exact mechanism for nanostructures to influence the LIB performance remains largely elusive. In this work, we discover the nanostructure-mediated lithiation mechanism in Co<sub>3</sub>O<sub>4</sub> anodes using <i>ex situ</i> transmission electron ... Read more >>

ACS Appl Mater Interfaces (ACS applied materials & interfaces)
[2021, 13(24):28171-28180]

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Chloroplast phylogenomics and divergence times of Lagerstroemia (Lythraceae).

Wenpan Dong, Chao Xu, Yanlei Liu, Jipu Shi, Wenying Li, Zhili Suo,

<h4>Background</h4>Crape myrtles, belonging to the genus Lagerstroemia L., have beautiful paniculate inflorescences and are cultivated as important ornamental tree species for landscaping and gardening. However, the phylogenetic relationships within Lagerstroemia have remained unresolved likely caused by limited sampling and the insufficient number of informative sites used in previous studies.<h4>Results</h4>In this ... Read more >>

BMC Genomics (BMC genomics)
[2021, 22(1):434]

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A new discovery of STAT4 single nucleotide polymorphisms associated with hepatocellular carcinoma risk in Chinese Han population: a case-control study.

Xu Chao, Jieqiong Wu, Wei Zhang, Xuesong Feng, Luyan Zhao, Feng Huang, Chao Jiang,

<h4>Background</h4>Hepatocellular carcinoma (HCC) is a common fatal malignant tumor worldwide. STAT4 is HCC susceptibility gene identified by genome-wide association study. The purpose of this study was to determine the association between four candidate single nucleotide polymorphisms (SNPs) in STAT4 genes and HCC risk in Chinese Han population.<h4>Methods</h4>A case-control study was ... Read more >>

Biosci Rep (Bioscience reports)
[2021, :]

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Characteristics and possible mechanisms of 46, XY differences in sex development caused by novel compound variants in NR5A1 and MAP3K1.

Yiping Cheng, Jing Chen, Xinli Zhou, Jiangfei Yang, Yiming Ji, Chao Xu,

<h4>Background</h4>Dozens of genes are involved in 46, XY differences in sex development (DSD). Notably, about 3/4 of patients cannot make a clear etiology diagnosis and single gene variant identified cannot fully explain the clinical heterogeneity of 46, XY DSD.<h4>Materials and methods</h4>We conducted a systematic clinical analysis of a 46, XY ... Read more >>

Orphanet J Rare Dis (Orphanet journal of rare diseases)
[2021, 16(1):268]

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