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Author Xiaoyan Zhou

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A paper-based SERS assay for sensitive duplex cytokine detection towards the atherosclerosis-associated disease diagnosis.

Chunxia Li, Yuan Liu, Xiaoyan Zhou, Yuling Wang,

Atherosclerosis (AS) is the most common factor causing many cardiovascular and cerebrovascular diseases and has received considerable attention. The occurrence mechanism of AS is uncertain because it is a choronically pathological process that is influenced by multi-aspects, among which cytokines play the key roles in regulating the processes of the ... Read more >>

J Mater Chem B (Journal of materials chemistry. B)
[2020, 8(16):3582-3589]

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Electric field triggered release of gas from a quasi-one-dimensional hydrate in the carbon nanotube.

Jiaxian Li, Hangjun Lu, Xiaoyan Zhou,

We systematically investigate the effects of an axial electric field on the formation and decomposition of quasi-one-dimensional nitrogen gas hydrates within a single-walled carbon nanotube (SWNT) by using molecular dynamics (MD) simulations. We find that the nitrogen hydrate in the SWNT undergoes a series of structure phase transitions with increasing ... Read more >>

Nanoscale (Nanoscale)
[2020, :]

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Theoretical Insights into the Excited State Decays of a Donor-Acceptor Dyad: Is the Twisted and Rehybridized Intramolecular Charge-Transfer State Involved?

Zhangrong Lou, Xiaoyan Zhou, Zhe Tang, Panwang Zhou,

The twisted intramolecular charge transfer has been proposed for a number of years and widely accepted to explain the excited-state dynamics of organic molecules. Recently, a new state termed as "twisted and rehybridized intramolecular charge transfer" has been proposed to explain the excited-state dynamics of an aniline-triazine electron donor-acceptor dyad ... Read more >>

J Phys Chem B (The journal of physical chemistry. B)
[2020, :]

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Simple pyrolysis of alginate-based hydrogel cross-linked by bivalent ions into highly porous carbons for energy storage.

Weimin Chen, Min Luo, Kai Yang, Xiaoyan Zhou,

Searching for a sustainable precursor that is capable of absorbing microwave energy is crucial for its rapid conversion into porous carbon via microwave heating. Here, alginate-based hydrogel beads cross-linked by bivalent ions (Cu2+, Zn2+, and Ca2+) are converted into porous carbons (SPCs) in 10 min by applying simple microwave-assisted pyrolysis. Water ... Read more >>

Int. J. Biol. Macromol. (International journal of biological macromolecules)
[2020, 158:265-274]

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Bright-yellow-emissive nitrogen-doped carbon nanodots as a fluorescent nanoprobe for the straightforward detection of glutathione in food samples.

Qin Hu, Huijuan Sun, Xiaoyan Zhou, Xiaojuan Gong, Lixia Xiao, Lizhen Liu, Zhen-Quan Yang,

In this work, a novel yellow-emissive nanoprobe was for the first time developed for the fast detection of glutathione (GSH) based on nitrogen-doped carbon nanodots (N-CNDs) prepared via hydrothermal heating of o-Phenylenediamine. The N-CNDs and GSH could form non-fluorescent complex via static interaction, resulting in the fluorescence quenching of N-CNDs. ... Read more >>

Food Chem (Food chemistry)
[2020, 325:126946]

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Glycemic variability indices determined by self-monitoring of blood glucose are associated with β-cell function in Chinese patients with type 2 diabetes.

Yusheng Zhang, Jiao Dai, Xiao Han, Yue Zhao, Hui Zhang, Xuan Liu, Wei Li, Hongwei Ling, Xiaoyan Zhou, Changjiang Ying,

INTRODUCTION:Glycemic control plays an important role in diabetes management, and self-monitoring of blood glucose (SMBG) is critical to achieving good glycemic control. However, there are few studies about the relationship between SMBG-estimated glycemic indices and β-cell function. Here we investigated the association between glucose variation indices estimated by SMBG and ... Read more >>

Diabetes Res. Clin. Pract. (Diabetes research and clinical practice)
[2020, 164:108152]

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Casein phosphopeptide combined with fluoride enhances the inhibitory effect on initial adhesion of Streptococcus mutans to the saliva-coated hydroxyapatite disc

Xiaodie Wang, Limin Liu, Xiaoyan Zhou, Yongbiao Huo, Jinlong Gao, Haijing Gu,

Abstract Background: Recent preventive strategies for dental caries focus on targeting the mechanisms underlying biofilm formation, including inhibiting bacterial adhesion. A promising approach to prevent bacterial adhesion is to modify the composition of acquired salivary pellicle. This in vitro study investigated the effect and possible underlying mechanism of pellicle modification ... Read more >>

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Correction: Nanoporous two-dimensional MoS2 membranes for fast saline solution purification.

Jianlong Kou, Jun Yao, Lili Wu, Xiaoyan Zhou, Hangjun Lu, Fengmin Wu, Jintu Fan,

Correction for 'Nanoporous two-dimensional MoS2 membranes for fast saline solution purification' by Jianlong Kou et al., Phys. Chem. Chem. Phys., 2016, 18, 22210-22216. ... Read more >>

Phys Chem Chem Phys (Physical chemistry chemical physics : PCCP)
[2020, 22(15):8235]

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Transplantation of IFN-γ Primed hUCMSCs Significantly Improved Outcomes of Experimental Autoimmune Encephalomyelitis in a Mouse Model.

Xiaoyan Zhou, Xiaoli Liu, Li Liu, Chao Han, Zhaohong Xie, Xiangtian Liu, Yingying Xu, Fan Li, Jianzhong Bi, Chengyun Zheng,

The aim of this study was to investigate potential therapeutic effects of IFN-γ primed human umbilical cord mesenchymal stem cell (IFN-γ-hUCMSCs) transplantation on experimental autoimmune encephalomyelitis (EAE) in mice. In this study, EAE mouse model was established by MOG35-55 immunization method. Outcomes of the EAE mice in terms of body ... Read more >>

Neurochem. Res. (Neurochemical research)
[2020, :]

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Association of IGF-1 gene rs2195239 polymorphism with the risk and clinical features of gastric cancer in a Chinese Han population.

Pengli Wang, Xiaoyan Zhou,

BACKGROUND:Recently, a Japanese study investigated the relationship between insulin-like growth factor-1 (IGF-1) gene rs2195239 polymorphism and gastric cancer (GC) risk and found rs2195239 polymorphism did not relate with the risk of GC. However, no Chinese studies have addressed this relationship until now. Thus, the aims of this study were to ... Read more >>

J. Clin. Lab. Anal. (Journal of clinical laboratory analysis)
[2020, :e23284]

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Impact of the Updated 2018 American Society of Clinical Oncology/College of American Pathologists Guideline for Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer.

Anqi Li, Qianming Bai, Hui Kong, Shuling Zhou, Hong Lv, Siyuan Zhong, Ming Li, Rui Bi, Xiaoyan Zhou, Wentao Yang,

CONTEXT.—:The updated American Society of Clinical Oncology/College of American Pathologists guideline for human epidermal growth factor receptor 2 (HER2) testing in breast cancer requires pathologists to re-evaluate HER2 status. OBJECTIVE.—:To define HER2 status of breast cancer using immunohistochemistry and fluorescence in situ hybridization. DESIGN.—:Diagnostic reports of invasive breast cancers made ... Read more >>

Arch. Pathol. Lab. Med. (Archives of pathology & laboratory medicine)
[2020, :]

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Dihydroartemisinin inhibits the tumorigenesis and metastasis of breast cancer via downregulating CIZ1 expression associated with TGF-β1 signaling.

Yue Li, Xiaoyan Zhou, Jiali Liu, Ning Gao, Ruihua Yang, Qi Wang, Jing Ji, Ling Ma, Qian He,

AIMS:Dihydroartemisinin (DHA) is currently considered as the promising cancer therapeutic drug. In this study, we aimed to investigate the anti-proliferative and anti-metastasis effects of DHA. MAIN METHODS:Utilizing breast cancer cells MCF-7, MDA-MB-231 and BT549, cell proliferation, migration and invasion were detected. RT-qPCR was performed to detect CIZ1, TGF-β1 and Snail ... Read more >>

Life Sci. (Life sciences)
[2020, 248:117454]

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Sentinel node theory helps tracking of primary lesions of cancers of unknown primary

Yilin Shao, Xin Liu, Silong Hu, Yingjian Zhang, Wentao Li, Xiaoyan Zhou, Qifeng Wang, Yifeng Hou, Yong Chen, Yanli Wang, Yaohui Wang, Zhiguo Luo, Xichun Hu,

Abstract Background: Sentinel lymph node is the first stop of lymphatic spreading of cancer with known primary. The lymph node metastasis pattern of cancer of unknown primary (CUP) is unclear and has been presumed to follow the same pathway. To test this hypothesis, data of all 716 patients clinically diagnosed ... Read more >>

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Microsatellite instability and its associations with the clinicopathologic characteristics of diffuse large B-cell lymphoma.

Tian Tian, Jiwei Li, Tian Xue, Baohua Yu, Xiaoqiu Li, Xiaoyan Zhou,

Microsatellite instability (MSI) has been investigated as a prognostic and predictive factor for chemotherapy in colorectal cancer and has recently been demonstrated to be predictive of the PD-1/PD-L1 checkpoint blockade response in various solid tumors. However, MSI status in diffuse large B-cell lymphomas (DLBCLs) has not been thoroughly explored. This ... Read more >>

Cancer Med (Cancer medicine)
[2020, 9(7):2330-2342]

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A protocol for a pilot randomized controlled trial of guided self-help Behavioral Activation intervention for geriatric depression

Xiaoxia Wang, Xiaoyan Zhou, Hui Yang,

Background: Aging is a social concern. Despite increased incidence of depression in Chinese older populations, they are often misdiagnosed and undertreated, which pose a challenge to our health care system. Depressed older adults often suffer from lack of motivation. Evidence-based guided self-help behavioral activation treatment is effective in reducing anhedonia ... Read more >>

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A simple fluorescence biosensing strategy for ultrasensitive detection of the BCR-ABL1 fusion gene based on a DNA machine and multiple primer-like rolling circle amplification.

Haiping Wu, Xiaoyan Zhou, Wei Cheng, Taixian Yuan, Min Zhao, Xiaolei Duan, Shijia Ding,

A one-step, rapid fluorescence biosensing method has been developed for ultrasensitive detection of the BCR-ABL1 fusion gene based on a polymerase/nicking endonuclease DNA machine and multiple primer-like rolling circle amplification (RCA). In the strategy, the BCR-ABL1 fusion gene can be specifically identified by using a dual probe to form a ... Read more >>

Analyst (The Analyst)
[2018, 143(20):4974-4980]

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Intense basolateral membrane staining indicates HER2 positivity in invasive micropapillary breast carcinoma.

Shuling Zhou, Fei Yang, Qianming Bai, Anqi Li, Ming Li, Siyuan Zhong, Hong Lv, Ruohong Shui, Xiaoyu Tu, Rui Bi, Xiaoli Xu, Yufan Cheng, Baohua Yu, Shaoxian Tang, Xiangjie Sun, Xiaoyan Zhou, Wentao Yang,

Invasive micropapillary carcinoma is characterized by the inside-out growth of tumor clusters and displays incomplete membrane immunostaining of HER2. According to the 2018 American Society of Clinical Oncology and the College of American Pathologists (ASCO/CAP) HER2-testing recommendation, moderate to intense but incomplete staining could be scored as immunohistochemical 2+. Furthermore, ... Read more >>

Mod. Pathol. (Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc)
[2020, :]

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Therapeutic Potentials and Mechanisms of Artemisinin and its Derivatives for Tumorigenesis and Metastasis.

Yue Li, Xiaoyan Zhou, Jiali Liu, Xiaohong Yuan, Qian He,

BACKGROUND:Tumor recurrence and metastasis are still leading causes of cancer mortality worldwide. The influence of traditional treatment strategies against metastatic tumor may still be limited. To search for novel and powerful agents against tumors become a major research focus. In this study, Artemisinin (ARM), a natural compound isolated from herbs, ... Read more >>

Anticancer Agents Med Chem (Anti-cancer agents in medicinal chemistry)
[2020, :]

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Formation of biofilms from new pipelines at both ends of the drinking water distribution system and comparison of disinfection by-products formation potential.

Huanyu Chen, Zongyuan Wei, Guangyu Sun, Hang Su, Jingqing Liu, Baolan Hu, Xiaoyan Zhou, Liping Lou,

The gradual updating of the water supply network is one of the crucial ways to ensure the safety of drinking water all over the world. The phenomenon and regularity of the biological risk and chemical risk of biofilms of the new pipes in drinking water distribution system (DWDS) is inadequate ... Read more >>

Environ. Res. (Environmental research)
[2020, 182:109150]

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Differentially expressed genes and key molecules of BRCA1/2-mutant breast cancer: evidence from bioinformatics analyses.

Yue Li, Xiaoyan Zhou, Jiali Liu, Yang Yin, Xiaohong Yuan, Ruihua Yang, Qi Wang, Jing Ji, Qian He,

Background:BRCA1 and BRCA2 genes are currently proven to be closely related to high lifetime risks of breast cancer. To date, the closely related genes to BRCA1/2 mutations in breast cancer remains to be fully elucidated. This study aims to identify the gene expression profiles and interaction networks influenced by BRCA1/2 ... Read more >>

PeerJ (PeerJ)
[2020, 8:e8403]

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Atmospheric Low-Temperature Plasma-Induced Changes in the Structure of the Lignin Macromolecule: An Experimental and Theoretical Investigation.

Yizhong Cao, Miao Tang, Pei Yang, Minzhi Chen, Siqun Wang, Haiming Hua, Weimin Chen, Xiaoyan Zhou,

Atmospheric low-temperature plasma has emerged as a promising pretreatment for lignocellulose to improve bio-refining. Herein, we investigated plasma-induced changes in the chemical structure of lignin to obtain a fundamental understanding of the plasma-lignocellulose interaction. Based on the results, plasma possesses a strong capacity to cleave C-C covalent bonds in the ... Read more >>

J. Agric. Food Chem. (Journal of agricultural and food chemistry)
[2020, 68(2):451-460]

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Rapid one-step preparation of hierarchical porous carbon from chitosan-based hydrogel for high-rate supercapacitors: The effect of gelling agent concentration.

Min Luo, Xin Wang, Taotao Meng, Pei Yang, Ziqi Zhu, Huihua Min, Minzhi Chen, Weimin Chen, Xiaoyan Zhou,

Herein, chitosan-based hydrogel beads (CHBs) were used to prepare N- and O-enriched hierarchical porous carbon (PC) by microwave heating for only 10 min. Water molecules in CHBs can act as heating carriers, and the resulting steam not only squeeze out air to create an oxygen-free atmosphere but act as physical activating ... Read more >>

Int. J. Biol. Macromol. (International journal of biological macromolecules)
[2020, 146:453-461]

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Genomic and immune profiling of pre-invasive lung adenocarcinoma.

Haiquan Chen, Jian Carrot-Zhang, Yue Zhao, Haichuan Hu, Samuel S Freeman, Su Yu, Gavin Ha, Alison M Taylor, Ashton C Berger, Lindsay Westlake, Yuanting Zheng, Jiyang Zhang, Aruna Ramachandran, Qiang Zheng, Yunjian Pan, Difan Zheng, Shanbo Zheng, Chao Cheng, Muyu Kuang, Xiaoyan Zhou, Yang Zhang, Hang Li, Ting Ye, Yuan Ma, Zhendong Gao, Xiaoting Tao, Han Han, Jun Shang, Ying Yu, Ding Bao, Yechao Huang, Xiangnan Li, Yawei Zhang, Jiaqing Xiang, Yihua Sun, Yuan Li, Andrew D Cherniack, Joshua D Campbell, Leming Shi, Matthew Meyerson,

Adenocarcinoma in situ and minimally invasive adenocarcinoma are the pre-invasive forms of lung adenocarcinoma. The genomic and immune profiles of these lesions are poorly understood. Here we report exome and transcriptome sequencing of 98 lung adenocarcinoma precursor lesions and 99 invasive adenocarcinomas. We have identified EGFR, RBM10, BRAF, ERBB2, TP53, ... Read more >>

Nat Commun (Nature communications)
[2019, 10(1):5472]

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Fast oxygen, nitrogen co-functionalization on electrospun lignin-based carbon nanofibers membrane via air plasma for energy storage application.

Wei Zhang, Pei Yang, Min Luo, Xin Wang, Tao Zhang, Weimin Chen, Xiaoyan Zhou,

The conventional method of thermal post-modification for introducing heteroatom into carbon nanofiber (CNF) generally suffered from some drawbacks in high-cost preparation and requirement of extra chemical agents. Herein, a more cost-efficient method based on air plasma was applied to introduce oxygen/nitrogen into lignin-based carbon nanofiber (LCNF). Massive free radicals (N, ... Read more >>

Int. J. Biol. Macromol. (International journal of biological macromolecules)
[2020, 143:434-442]

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Inhibition of HDAC6 alleviating lipopolysaccharide-induced p38MAPK phosphorylation and neuroinflammation in mice.

Yuanjian Song, Li Qin, Rongli Yang, Fan Yang, Nwobodo Alexander Kenechukwu, Xiaofang Zhao, Xiaoyan Zhou, Xiangru Wen, Lei Li,

Context: Researchers in a variety of fields have extensively focused on histone deacetylase 6 (HDAC6) due to its aggravation of inflammatory reaction. However, relevant studies examining whether HDAC6 could exacerbate lipopolysaccharide (LPS)-induced inflammation are still lacking. Objective: We assessed the role of HDAC6 in LPS-induced brain inflammation and used the ... Read more >>

Pharm Biol (Pharmaceutical biology)
[2019, 57(1):263-268]

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