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Author Xiaoping Tian

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Association Between the Alterations in the Blood Routine Check Parameters and Cognitive Impairment in the Shenzhen Ageing-related Disorder Cohort in China

Kaiyu Wu, Chunyan Xu, Xiaoping Tian, Guozhen Qiu, Wei Liu, Qiwen Guo, Xueya Meng, Chunchun Chen, Jianjun Liu, Zhiwei Guo, Haifei Chen, Kangding Liu, Feiqi Zhu,

<h4>Background: </h4> Previous studies have suggested a correlation between alterations in the routine blood check markers and cognitive impairment. <h4>Objective: </h4> We aimed to explore the relationship between routine blood parameters and cognitive impairment. <h4>Methods: </h4>: In this retrospective case-control study, 8,025 people over 60 years of age were enrolled ... Read more >>

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Robust Deep Kernel-Based Fuzzy Clustering With Spatial Information for Image Segmentation

Lujia Lei, Chengmao Wu, Xiaoping Tian,

Clustering algorithms with deep neural network have attracted wide attention of scholars. A deep fuzzy K-means clustering algorithm model with adaptive loss function and entropy regularization (DFKM) is proposed by combining automatic encoder and clustering algorithm. Although it introduces adaptive loss function and entropy regularization to improve the robustness of ... Read more >>

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Can Control Infections Slow Down the Progression of Alzheimer's Disease? Talking About the Role of Infections in Alzheimer's Disease.

Mingchao Shi, Chunrong Li, Xiaoping Tian, Fengna Chu, Jie Zhu,

Alzheimer's disease as the most common age-related dementia affects more than 40 million people in the world, representing a global public health priority. However, the pathogenesis of Alzheimer's disease (AD) is complex, and it remains unclear. Over the past decades, all efforts made in the treatments of AD, with targeting ... Read more >>

Front Aging Neurosci (Frontiers in aging neuroscience)
[2021, 13:685863]

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Kernel-Based Fuzzy Local Information Clustering Algorithm Self-integrating Non-Local Information

Qiuyu Song, Chengmao Wu, Xiaoping Tian, Yue Song, Xiaokang Guo,

The application of fuzzy clustering algorithms in image segmentation is a hot research topic nowadays. Existing fuzzy clustering algorithms have the following three problems: (1)The parameters of spatial information constraints can$'$t be selected adaptively; (2)The image corrupted by high noise can$'$t be segmented effectively; (3)It is difficult to achieve a ... Read more >>

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Role of Adaptive Immune and Impacts of Risk Factors on Adaptive Immune in Alzheimer's Disease: Are Immunotherapies Effective or Off-Target?

Mingchao Shi, Fengna Chu, Xiaoping Tian, Qiaolifan Aerqin, Feiqi Zhu, Jie Zhu,

The pathogenesis of Alzheimer's disease (AD) is complex. Still it remains unclear, which resulted in all efforts for AD treatments with targeting the pathogenic factors unsuccessful over past decades. It has been evidenced that the innate immune is strongly implicated in the pathogenesis of AD. However, the role of adaptive ... Read more >>

Neuroscientist (The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry)
[2021, :1073858420987224]

Cited: 1 time

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Target Dysbiosis of Gut Microbes as a Future Therapeutic Manipulation in Alzheimer's Disease.

Feiqi Zhu, Chunrong Li, Fengna Chu, Xiaoping Tian, Jie Zhu,

Alzheimer's disease (AD) is commonly an age-associated dementia with neurodegeneration. The pathogenesis of AD is complex and still remains unclear. The inflammation, amyloid β (Aβ), and neurofibrillary tangles as well misfolded tau protein in the brain may contribute to the occurrence and development of AD. Compared with tau protein, Aβ ... Read more >>

Front Aging Neurosci (Frontiers in aging neuroscience)
[2020, 12:544235]

Cited: 7 times

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[Effects of different signal peptides on the secretion of human-mouse chimeric CMV-IgM].

Yamin Cui, Xiaoping Tian, Qiaohui Zhao, Guilin Li,

In order to prepare human-mouse chimeric cytomegalovirus-immunoglobulin M (CMV-IgM) in vitro and study the effects of different signal peptides on the secretion of CMV-IgM, genes were amplified from hybridoma cell line using RLM-RACE to construct the expression vector of chimeric CMV-IgM. Then, the signal peptide of SigF itself was replaced ... Read more >>

Sheng Wu Gong Cheng Xue Bao (Sheng wu gong cheng xue bao = Chinese journal of biotechnology)
[2020, 36(6):1223-1231]

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Which subtype of functional dyspepsia patients responses better to acupuncture? A retrospective analysis of a randomized controlled trial.

Tingting Ma, Fang Zeng, Ying Li, Chieh-Mei Wang, Xiaoping Tian, Shuyuan Yu, Ling Zhao, Xi Wu, Min Yang, Dejun Wang, Fanrong Liang,

Whether subgroups of functional dyspepsia (FD) should be treated with different approaches is controversially discussed in research. As our previous study has demonstrated the effect of acupuncture in FD treatment, we now further analyze the therapeutic effect of acupuncture in the treatment of postprandial distress syndrome (PDS) and epigastric pain ... Read more >>

Forsch Komplementmed (Forschende Komplementarmedizin (2006))
[2015, 22(2):94-100]

Cited: 9 times

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Acupuncture for treating acute attacks of migraine: a randomized controlled trial.

Ying Li, Fanrong Liang, Xuguang Yang, Xiaoping Tian, Jie Yan, Guojie Sun, Xiaorong Chang, Yong Tang, Tingting Ma, Li Zhou, Lei Lan, Wen Yao, Ran Zou,

<h4>Objective</h4>To discuss the results of a multicenter randomized controlled trial of the efficacy of verum acupuncture in treating acute migraine attacks.<h4>Background</h4>Acupuncture has been used in China for centuries to treat migraine headache. Convincing evidence of its efficacy in alleviating pain, however, has been inadequate to date.<h4>Methods</h4>A total of 218 patients ... Read more >>

Headache (Headache)
[2009, 49(6):805-816]

Cited: 44 times

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Randomized controlled trial to treat migraine with acupuncture: design and protocol.

Ying Li, Fanrong Liang, Shuguang Yu, Xuguang Liu, Yong Tang, Xuguang Yang, Xiaoping Tian, Jie Yan, Guojie Sun, Xiaorong Chang, Hui Zheng, Hongxing Zhang, Tingting Ma,

<h4>Background and motivation</h4>The effectiveness of using acupuncture to treat migraine is rarely and even suspectedly reported in the literature. In this article, we report the design and the protocol of a randomized controlled large-scale trial to treat migraine using acupuncture, aiming at testifying it is effective to use acupuncture to ... Read more >>

Trials (Trials)
[2008, 9:57]

Cited: 12 times

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Disclosure of the tuberous lectin composed of homogeneous tetramers in Pinellia pedatisecda Schott.

Xiaochuan Liu, Xiaoping Tian, Tong Liu, Jiangli Liang,

Pinellia pedatisecta (Schott) and Pinellia ternata (Thumb) Breit, whose tuberous stems are an important Chinese medicine, taxonomically belong to Pinellia, Araceae species. Pinellia contains various lectins in their tubers, leading to distinct roles in Chinese medicine. Difference of the lectins, however, is little known between P. pedatisecta and P. ternata ... Read more >>

Appl Biochem Biotechnol (Applied biochemistry and biotechnology)
[2010, 162(4):1214-1223]

Cited: 3 times

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Telomere and telomerase as targets for cancer therapy.

Xiaoping Tian, Bo Chen, Xiaochuan Liu,

Telomere maintenance and telomerase reactivation is essential for the transformation of most human cancer cells. Telomere shortening to the threshold length, mutations of the telomere-associated proteins, and/or telomerase RNA lead to telomeric dysfunction and therefore genomic instability. Telomerase up-regulation in 85% of human cancer cells has become a hallmark of ... Read more >>

Appl Biochem Biotechnol (Applied biochemistry and biotechnology)
[2010, 160(5):1460-1472]

Cited: 19 times

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Hydraulic squeezing type dewaterer for Acete chinensis

WEIBO LIANG, SHOUWEI ZHU, SHANGKUN DU, YI WANG, LIGUO CHEN, GUIZHI DU, GUOFU ZHENG, CHENGSHAN WANG, GUANG YANG, FENG WANG, WENLIANG ZHOU, XICHUN ZHAO, QINGSONG ZHAO, XIAOPING TIAN, ZHIHONG FENG,

Disclosed is a hydraulic extrusion type prawn dehydrator comprising a base, which is characterized in that: a cross beam is arranged on the base, an oil cylinder is disposed on the cross beam, a piston rod of the oil cylinder is vertical and faces downwards, the lower end of the ... Read more >>

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G-quadruplex structure: a target for anticancer therapy and a probe for detection of potassium.

Bo Chen, Jiangli Liang, Xiaoping Tian, Xiaochuan Liu,

G-Quadruplexes are four-stranded DNA structures that play important regulatory roles in the maintenance of telomere length by inhibiting telomerase activity. Telomeres are specialized functional DNA-protein structures consisting of a variable number of tandem G-rich repeats together with a group of specific proteins. Telomere losses during cell replication are compensated by ... Read more >>

Biochemistry (Mosc) (Biochemistry. Biokhimiia)
[2008, 73(8):853-861]

Cited: 7 times

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Artificial seedling method of blood clam

SHOUWEI ZHU, SHANGKUN DU, WEIBO LIANG, YUXIANG YANG, GUOFU ZHENG, ZHUO FU, GUANG YANG, YI WANG, WENLIANG ZHOU, XICHUN ZHAO, XIAOPING TIAN, ZHIHONG FENG, CHENGSHAN WANG, ZHANHUI WU, JIANGNING XIE, LIGUO CHEN,

A method of artificial breeding for ark shells, which includes cultivating unicellular algae first, then breeding, sampling and inspecting parent calms gonads of ark shells in the sea, capturing and transporting parent calms, breeding species shells temporarily in seeding room interiorly spawning and hatching parent calms selecting and breeding larvae, ... Read more >>

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