Full Text Journal Articles by
Author Xiaoli Huang

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Clinical Characteristics of 204 Children With Human Adenovirus Type 7 Pneumonia Identified by Whole Genome Sequencing in Liuzhou, China.

Xiaoli Huang, Yongsong Yi, Xiaogang Chen, Bo Wang, Yiqin Long, Jichang Chen, Chokechai Rongkavilit,

<h4>Background</h4>Clinical knowledge of human adenovirus type 7 (HAdV-7) pneumonia in children remains limited. Moreover, predictors for disease severity are largely unknown.<h4>Methods</h4>This is a retrospective study of children hospitalized at Liuzhou Maternal and Child Health Hospital, China, with HAdV-7 pneumonia in 2018-2019. Demographics, clinical characteristics, laboratory results, and imaging data were ... Read more >>

Pediatr Infect Dis J (The Pediatric infectious disease journal)
[2021, 40(2):91-95]

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Synthesis of Cyclopentadienes for Cyclopentadienyl Ligands via Cp*RhIII-Catalyzed Formal sp3 C-H Activation/Spiroannulations.

Yongzhuang Wang, Xiaoli Huang, Qin Wang, Yuhai Tang, Silong Xu, Yang Li,

An efficient Cp*Rh<sup>III</sup>-catalyzed formal C(sp<sup>3</sup>)-H activation/spiroannulation of alkylidene Meldrum's acids with alkynes has been developed using catalytical Cu(OAc)<sub>2</sub> and air as the oxidant. This reaction demonstrates a new and straightforward approach to spirocyclopentadienes with Meldrum's acid moieties in good to excellent yields under mild reaction conditions with a broad substrate ... Read more >>

Org Lett (Organic letters)
[2021, :]

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Synthesis of molecular metallic barium superhydride: pseudocubic BaH12.

Wuhao Chen, Dmitrii V Semenok, Alexander G Kvashnin, Xiaoli Huang, Ivan A Kruglov, Michele Galasso, Hao Song, Defang Duan, Alexander F Goncharov, Vitali B Prakapenka, Artem R Oganov, Tian Cui,

Following the discovery of high-temperature superconductivity in the La-H system, we studied the formation of new chemical compounds in the barium-hydrogen system at pressures from 75 to 173 GPa. Using in situ generation of hydrogen from NH<sub>3</sub>BH<sub>3</sub>, we synthesized previously unknown superhydride BaH<sub>12</sub> with a pseudocubic (fcc) Ba sublattice in four ... Read more >>

Nat Commun (Nature communications)
[2021, 12(1):273]

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ASK1/p38‑mediated NLRP3 inflammasome signaling pathway contributes to aberrant retinal angiogenesis in diabetic retinopathy.

Wenjun Zou, Shasha Luo, Zhengwei Zhang, Libo Cheng, Xiaoli Huang, Nannan Ding, Ying Pan, Zhifeng Wu,

Diabetic retinopathy (DR) is the leading cause of blindness among the working‑age population in several countries. Despite the available treatments, some patients are diagnosed at the late stages of the disease when treatment is more difficult. Hence, it is crucial that novel targets are identified in order to improve the ... Read more >>

Int J Mol Med (International journal of molecular medicine)
[2020, :]

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Infection-Induced Rhabdomyolysis in an Elderly Patient on Stable Rosuvastatin Therapy: A Case Report and Review of the Literature.

Daxin Guo, Zhangmin Meng, Fuqian He, Gongxiang Liu, Xiaoli Huang,

Am J Ther (American journal of therapeutics)
[2021, :]

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Clinical characteristics of deceased hemodialysis patients affected by COVID-19.

Yonglong Min, Li Cheng, Can Tu, Hongbo Li, Da He, Dan Huang, Dan Chen, Xiaoli Huang, Fang Chen, Fei Xiong,

<h4>Background</h4>The recent outbreak of Coronavirus Disease 2019 (COVID-19) is a public health emergency of international concern. In China, Wuhan, Hubei Province was the epicenter. The disease is more severe in patients with high comorbidities and dialysis patients fall into this category.<h4>Methods</h4>In this report, we reviewed the whole course of the ... Read more >>

Int Urol Nephrol (International urology and nephrology)
[2021, :]

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Novel Strongly Correlated Europium Superhydrides.

Dmitrii V Semenok, Di Zhou, Alexander G Kvashnin, Xiaoli Huang, Michele Galasso, Ivan A Kruglov, Anna G Ivanova, Alexander G Gavriliuk, Wuhao Chen, Nikolay V Tkachenko, Alexander I Boldyrev, Ivan Troyan, Artem R Oganov, Tian Cui,

We conducted a joint experimental-theoretical investigation of the high-pressure chemistry of europium polyhydrides at pressures of 86-130 GPa. We discovered several novel magnetic Eu superhydrides stabilized by anharmonic effects: cubic EuH<sub>9</sub>, hexagonal EuH<sub>9</sub>, and an unexpected cubic (<i>Pm</i>3<i>n</i>) clathrate phase, Eu<sub>8</sub>H<sub>46</sub>. Monte Carlo simulations indicate that cubic EuH<sub>9</sub> has antiferromagnetic ... Read more >>

J Phys Chem Lett (The journal of physical chemistry letters)
[2021, 12(1):32-40]

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Complete genome analysis of Vibrio mimicus strain SCCF01, a highly virulent isolate from the freshwater catfish.

Zehui Yu, Erlong Wang, Yi Geng, Kaiyu Wang, Defang Chen, Xiaoli Huang, Ping Ouyang, Zhicai Zuo, Chao Huang, Jing Fang, Lizi Yin, Hongrui Guo, Zhijun Zhong,

<i>Vibrio mimicus</i> is a foodborne pathogen, which is widely distributed in the aquatic environment. Moreover, it is often involved in aquatic animal diseases. In recent years, <i>V. mimicus</i> is an emerging pathogen in some species of Siluriformes. The strain SCCF01 was isolated from yellow catfish (<i>Pelteobagrus fulvidraco</i>). In this study, ... Read more >>

Virulence (Virulence)
[2020, 11(1):23-31]

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Nocardia seriolae: a serious threat to the largemouth bass Micropterus salmoides industry in Southwest China.

Xueping Lei, Ruoxuan Zhao, Yi Geng, Kaiyu Wang, Ping Ou Yang, Defang Chen, Xiaoli Huang, Zhicai Zuo, Changliang He, Zhengli Chen, Chao Huang, Hongrui Guo, Weimin Lai,

Nocardia seriolae is the causative agent of nocardiosis in both marine and freshwater fish. Here, we report on multiple outbreaks of nocardiosis associated with elevated mortality (23-35%) in farmed largemouth bass in Sichuan, China, from 2017 to 2018. A total of 9 strains isolated from diseased largemouth bass were identified ... Read more >>

Dis Aquat Organ (Diseases of aquatic organisms)
[2020, 142:13-21]

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Centrosome Protein 78 Is Overexpressed in Muscle-Invasive Bladder Cancer and Is Associated with Tumor Molecular Subtypes and Mutation Signatures.

Xiaoli Huang, Yang Yan, Rong Wei, Hu Liu, Xingchen Zhu, Dexi Bi, Qing Wei, Xudong Yao,

BACKGROUND Centrosome aberrations have long been linked to tumorigenesis. Centrosome protein 78 (CEP78) is a centrosome component that is required to regulate the cell cycle, but its role in bladder cancer has not been elucidated. MATERIAL AND METHODS Real-time quantitative polymerase chain reaction and immunohistochemistry were used to examine the ... Read more >>

Med Sci Monit (Medical science monitor : international medical journal of experimental and clinical research)
[2020, 26:e925197]

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The Roles of Base Modifications in Kidney Cancer.

Chunyue Feng, Xiaoli Huang, Xuekun Li, Jianhua Mao,

Epigenetic modifications including histone modifications and DNA and RNA modifications are involved in multiple biological processes and human diseases. One disease, kidney cancer, includes a common type of tumor, accounts for about 2% of all cancers, and usually has poor prognosis. The molecular mechanisms and therapeutic strategy of kidney cancer ... Read more >>

Front Oncol (Frontiers in oncology)
[2020, 10:580018]

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Disorder-order structural transition of single crystal hydrogen chloride under high pressure-temperature.

Mengya Lu, Di Zhou, Fangfei Li, Yongfu Liang, Qiang Zhou, Xiaoli Huang, Tian Cui,

Hydrogen chloride (HCl) is the simplest hydrogen-bonded molecule and has attracted a great deal of attention owing to its interesting structural changes triggered by pressure or temperature. The structural properties of solid HCl have been investigated by Brillouin scattering in the pressure range of 0-20 GPa under high temperature, combined ... Read more >>

Phys Chem Chem Phys (Physical chemistry chemical physics : PCCP)
[2019, 21(32):17655-17661]

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Increasement of Cd adsorption capacity of rice stubble from being alive until death in a modified rice-fish system.

Wei Luo, Ning Zhang, Zhengjie Li, Zhou Xu, Dongjie Wang, Guoping Liao, Guojun Pang, Guodong Xu, Yiyao Wang, Xiaoli Huang, Defang Chen, Cong Zeng, Zongjun Du,

Soil heavy metal contamination is an increasingly urgent problem throughout the world. Phytoremediation is a cost-effective and ecologically friendly in situ method for the remediation of heavy metal contaminated soils. Rice has the potential for use in soil remediation due to its high biomass production, however, risks related to food ... Read more >>

Ecotoxicol Environ Saf (Ecotoxicology and environmental safety)
[2021, 208:111441]

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Global gene expression profile under low-temperature conditions in the brain of the grass carp (Ctenopharyngodon idellus).

Mijuan Shi, Qiangxiang Zhang, Yongming Li, Wanting Zhang, Lanjie Liao, Yingyin Cheng, Yanxin Jiang, Xiaoli Huang, You Duan, Lei Xia, Weidong Ye, Yaping Wang, Xiao-Qin Xia,

Grass carp is an important commercial fish widely cultivated in China. A wide range of temperatures, particularly extremely low temperatures, have dramatic effects on the aquaculture of this teleost. However, relatively few studies have characterized the molecular responses of grass carp exposed to acute cooling in natural environment. Here, we ... Read more >>

PLoS One (PloS one)
[2020, 15(9):e0239730]

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The association between ambient air pollution and birth defects in five major ethnic groups in Liuzhou, China

Xiaoli Huang, Jichang Chen, Dingyuan Zeng, Zhong Lin, Carly Herbert, Lesley Cottrell, Liu Liu, Arlene Ash, Bo Wang,

<h4>Background: </h4> Studies suggest that exposure to ambient air pollution during pregnancy may be associated with increased risks of birth defects (BDs), but conclusions have been inconsistent. This study describes the ethnic distribution of major BDs and examines the relationship between air pollution and BDs among different ethnic groups in ... Read more >>

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Value of circulating miRNA-21 in the diagnosis of subclinical diabetic cardiomyopathy.

Lichan Tao, Xiaoli Huang, Min Xu, Zihan Qin, Feifei Zhang, Fei Hua, Xiaohong Jiang, Yuetao Wang,

<h4>Background</h4>Diabetic cardiomyopathy (DCM) is a type of cardiac dysfunction that affects approximately 12% of diabetic patients, ultimately leading to heart failure or even death. However, there is currently no efficient or specific biomarker for DCM diagnosis.<h4>Methods</h4>A total of 266 subjects with type II diabetes (T2DM) were enrolled in this study ... Read more >>

Mol Cell Endocrinol (Molecular and cellular endocrinology)
[2020, 518:110944]

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A cross-sectional study of Bayesian belief network modeling: Risk factors for hepatopancreatic necrosis syndrome of the Chinese mitten crab (Eriocheir sinensis) in China

Xiaoli Huang, Yang Feng, Guanqing Xiong, Liang Zhong, Sha Liu, Ping Fang, Hui Chen, Kaiyu Wang, Yi Geng, Ping Ouyang, Defang Chen, Shiyong Yang,

Hepatopancreatic necrosis syndrome (HPNS) has a severe impact on the Chinese mitten crab (Eriocheir sinensis) industry. In this work, a cross-sectional study method was used to assess the association between 55 variables and HPNS. A total of 98 farmers were surveyed, including 34 whose farms had crabs with HPNS (treated ... Read more >>

Aquaculture (Aquaculture (Amsterdam, Netherlands))
[2020, 524:Not Available]

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Characterization and antitumor activity of novel exopolysaccharide APS of Lactobacillus plantarum WLPL09 from human breast milk.

Bensheng Jiang, Linlin Tian, Xiaoli Huang, Zhengqi Liu, Kaiying Jia, Hua Wei, Xueying Tao,

Two exopolysaccharides, NPS and APS, were isolated from L. plantarum WLPL09 and purified by ion-exchange chromatography. The structural analyses showed that molecular weight of NPS and APS were 72.60 kDa and 33.22 kDa, respectively. NPS was mainly composed of mannose and glucose, in molar ratio of 85.35:14.65, while APS was composed of ... Read more >>

Int J Biol Macromol (International journal of biological macromolecules)
[2020, 163:985-995]

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Low lethal doses of Streptococcus iniae caused enteritis in Siberian sturgeon (Acipenser baerii).

Defang Chen, Shuang Peng, Daiyu Chen, Fei Yang, Jiaxi Liu, Jun Wang, Qiwei Liu, Xiaoli Huang, Ping Ouyang, Kaiyu Wang, Zhiqiong Li, Yi Geng,

In aquaculture, the incidence of enteritis due to Streptococcus iniae infection in Siberian sturgeon (Acipenser baerii) has increased in recent years. The pathogenesis of S. iniae is largely unknown due to the paucity of experimental studies on fish intestinal inflammation. In this study, S. iniae infection of A. baerii juveniles ... Read more >>

Fish Shellfish Immunol (Fish & shellfish immunology)
[2020, 104:654-662]

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Effects of cadmium pollution on the safety of rice and fish in a rice-fish coculture system.

Wei Luo, Dongjie Wang, Zhou Xu, Guoping Liao, Defang Chen, Xiaoli Huang, Yan Wang, Song Yang, Liulan Zhao, Huagang Huang, Yuliang Li, Wenyan Wei, Yuejin Long, Zongjun Du,

The rice-fish coculture system (RFS) is one of the most important and environmentally friendly agricultural systems in the world. With the increasing amounts of heavy metal contamination in the soil and water, the safe production of RFS has been greatly threatened. However, there are no reports on heavy metal uptake ... Read more >>

Environ Int (Environment international)
[2020, 143:105898]

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Neutrophil: lymphocyte ratio is positively associated with subclinical diabetic cardiomyopathy.

Xiaoli Huang, Zihan Qin, Min Xu, Feifei Zhang, Xiaohong Jiang, Fei Hua, Lichan Tao,

<h4>Background</h4>Subclinical diabetic cardiomyopathy (DCM) occurs frequently in asymptomatic subjects with Type 2 diabetes mellitus (T2DM). The direct association between the immune system and DCM with effective biomarkers has been demonstrated in previous studies.<h4>Methods</h4>Five hundred seven subjects with T2DM were recruited from April 2018 to October 2019 and divided into T2DM ... Read more >>

BMC Endocr Disord (BMC endocrine disorders)
[2020, 20(1):99]

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A synonymous mutation in exon 39 of FBN1 causes exon skipping leading to Marfan syndrome.

Mingjie Li, Xinxin Lu, Jian Dong, Zuwu Yao, Yinlong Wu, Huiying Rao, Xiaoli Huang, Xijun Chen, Yi Huang, Yan'an Wu,

Marfan syndrome is a heritable autosomal-dominant connective tissue disorder and it was typically caused by mutations in FBN1. However, the synonymous mutation was seldom recorded to be related to Marfan syndrome. Hereon, Multiplex ligation-dependent probe amplification failed to detect a copy number variant involving FBN1 but a synonymous mutation c.4773A > G ... Read more >>

Genomics (Genomics)
[2020, 112(6):3856-3861]

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Piezoelectric and pyroelectric properties of Mn-doped 0.36Pb(In1/2Nb1/2)O3-0.36Pb(Mg1/3Nb2/3)O3-0.28PbTiO3 ceramics

Xiaoli Huang, Yanxue Tang, Feifei Wang, Xiangyong Zhao, Zhihua Duan, Tao Wang, Qiuxiang Du, Jiasheng Wang, Xingtong Zhou, Wangzhou Shi,

Piezoelectric and pyroelectric properties as well as strain behavior of 0.5 mol% Mn-doped 0.36Pb(In 1/2 Nb 1/2 )O 3 -0.36Pb(Mg 1/3 Nb 2/3 )O 3 -0.28PbTiO 3 (Mn-PIMNT) ceramics were studied. High piezoelectric coefficient of d 33 = 235 pC/N, planar electromechanical coupling factor of k p = 43.1% and ... Read more >>

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p38 promoted retinal micro-angiogenesis through up-regulated RUNX1 expression in diabetic retinopathy.

Wenjun Zou, Zhengwei Zhang, Shasha Luo, Libo Cheng, Xiaoli Huang, Nannan Ding, Jinjin Yu, Ying Pan, Zhifeng Wu,

Diabetic retinopathy (DR) is the most common microvascular complication of diabetes and is characterized by visible microvascular alterations including retinal ischemia-reperfusion injury, inflammation, abnormal permeability, neovascularization and macular edema. Despite the available treatments, some patients present late in the course of the disease when treatment is more difficult. Hence, it ... Read more >>

Biosci Rep (Bioscience reports)
[2020, 40(5):]

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Discovery of N-Ethyl-4-[2-(4-fluoro-2,6-dimethyl-phenoxy)-5-(1-hydroxy-1-methyl-ethyl)phenyl]-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxamide (ABBV-744), a BET Bromodomain Inhibitor with Selectivity for the Second Bromodomain.

George S Sheppard, Le Wang, Steven D Fidanze, Lisa A Hasvold, Dachun Liu, John K Pratt, Chang H Park, Kenton Longenecker, Wei Qiu, Maricel Torrent, Peter J Kovar, Mai Bui, Emily Faivre, Xiaoli Huang, Xiaoyu Lin, Denise Wilcox, Lu Zhang, Yu Shen, Daniel H Albert, Terrance J Magoc, Ganesh Rajaraman, Warren M Kati, Keith F McDaniel,

The BET family of proteins consists of BRD2, BRD3, BRD4, and BRDt. Each protein contains two distinct bromodomains (BD1 and BD2). BET family bromodomain inhibitors under clinical development for oncology bind to each of the eight bromodomains with similar affinities. We hypothesized that it may be possible to achieve an ... Read more >>

J Med Chem (Journal of medicinal chemistry)
[2020, 63(10):5585-5623]

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