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Author Xiaolei Yao

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LncRNA-412.25 activates the LIF/STAT3 signaling pathway in ovarian granulosa cells of Hu sheep by sponging miR-346.

Xiaolei Yao, Mohamed AbdFatah El-Samahy, Xiaodan Li, Yongjin Bao, Jiahe Guo, Fan Yang, Zhibo Wang, Kang Li, Yanli Zhang, Feng Wang,

Although long non-coding RNAs (lncRNAs) are reported to regulate follicular development and reproductive disease pathogenesis, the underlying mechanisms have not been elucidated. In this study, lncRNA expression profiling of different-sized healthy follicles from Hu sheep with different prolificacy revealed 50 613 lncRNAs. Numerous lncRNAs were differentially expressed among different comparison groups. ... Read more >>

FASEB J (FASEB journal : official publication of the Federation of American Societies for Experimental Biology)
[2022, 36(9):e22467]

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The Novel Competing Endogenous Long Noncoding RNA SM2 Regulates Gonadotropin Secretion in the Hu Sheep Anterior Pituitary by Targeting the Oar-miR-16b/TGF-β/SMAD2 Signaling Pathway.

Zhen Wan, Hua Yang, Peiyong Chen, Zhibo Wang, Yu Cai, Xiaolei Yao, Feng Wang, Yanli Zhang,

Pituitary gonadotropins play a pivotal role in reproduction. Long noncoding RNAs (lncRNAs) have been identified as important regulators in the hypothalamic-pituitary-ovarian (HPO) axis associated with reproduction. However, the contributions of lncRNAs to pituitary gonadotropin secretion remain largely unknown. Therefore, this work was performed to uncover the functional mechanisms of the ... Read more >>

Cells (Cells)
[2022, 11(6):985]

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