Full Text Journal Articles by
Author Xiaojie Wang

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Colorimetric analysis of extracellular vesicle surface proteins based on controlled growth of Au aptasensors.

Xiaojie Wang, Xinxin Yuan, Kexin Fu, Chang Liu, Lu Bai, Xinchao Wang, Xiaoyue Tan, Yuying Zhang,

Protein profiling of extracellular vesicles (EVs) provides important information in both clinical cancer diagnosis and relevant biological research studies. Although a variety of bioanalytical techniques have been investigated for EV characterization, limitations such as time-consuming operations, the requirement of large sample volume and demand for specialized instruments hinder their practical ... Read more >>

Analyst (The Analyst)
[2021, 146(6):2019-2028]

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A proteomic study on the protective effect of kaempferol pretreatment against deoxynivalenol-induced intestinal barrier dysfunction in a Caco-2 cell model.

Xiaojie Wang, Li Li, Genyi Zhang,

Deoxynivalenol (DON) is one of the most widely distributed mycotoxins in the food chain, and the protective effect of kaempferol (KAM) pretreatment against the barrier dysfunction induced by DON in a Caco-2 cell model was investigated using a proteomic approach. The results showed that after KAM pretreatment, both the numbers ... Read more >>

Food Funct (Food & function)
[2020, 11(8):7266-7279]

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CLEC14A protects against podocyte injury in mice with adriamycin nephropathy.

Zeyu Su, Yujia Li, Hang Lv, Xiaoyang Cui, Min Liu, Ziying Wang, Yan Zhang, Junhui Zhen, Wei Tang, Xiaojie Wang, Fan Yi,

Podocyte injury is a major determinant of focal segmental glomerular sclerosis (FSGS) and the identification of potential therapeutic targets for preventing podocyte injury has clinical importance for the treatment of FSGS. CLEC14A is a single-pass transmembrane glycoprotein belonging to the vascular expressed C-type lectin family. CLEC14A is found to be ... Read more >>

FASEB J (FASEB journal : official publication of the Federation of American Societies for Experimental Biology)
[2021, 35(7):e21711]

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Individualized conditional survival nomograms for patients with locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy and radical surgery.

Zhifang Zheng, Xiaojie Wang, Zhun Liu, Xingrong Lu, Ying Huang, Pan Chi,

<h4>Background</h4>Conditional survival (CS) considers the time already survived after surgery when estimating the survival probability, which may provide further useful prognostic information.<h4>Objective</h4>To evaluate CS in patients with locally advanced rectal cancer (LARC) treated with neoadjuvant chemoradiotherapy (nCRT) and to create CS nomograms predicting the conditional probability of survival after proctectomy.<h4>Methods</h4>Consecutive ... Read more >>

Eur J Surg Oncol (European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology)
[2021, :]

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Potential biomarkers for inherited thrombocytopenia 2 identified by plasma proteomics.

Xiaojie Wang, Maoshan Chen, Limeng Dai, Chengning Tan, Lanyue Hu, Yichi Zhang, Yanni Xiao, Fengjie Li, Cheng Zeng, Zheng Xiang, Yali Wang, Weiwei Zhang, Xiaomei Zhang, Qian Ran, Zhongjun Li, Li Chen,

Inherited thrombocytopenia 2 (THC2) is difficult to diagnose due to the lack of specific clinical characteristics and diagnostic methods. To identify potential plasma protein biomarkers for THC2, we collected the plasma samples from a THC2 family (9 THC2 and 15 non-THC2 members), enriched the medium and low abundant proteins using ... Read more >>

Platelets (Platelets)
[2021, :1-8]

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Comparative effectiveness and safety of direct acting oral anticoagulants in nonvalvular atrial fibrillation for stroke prevention: a systematic review and meta-analysis.

Junguo Zhang, Xiaojie Wang, Xintong Liu, Torben B Larsen, Daniel M Witt, Zebing Ye, Lehana Thabane, Guowei Li, Gregory Y H Lip,

<h4>Purpose</h4>To systematically review available evidence of indirect comparisons from RCTs and direct comparisons from observational studies regarding the comparative effectiveness and safety of DOACs in patients with AF.<h4>Methods</h4>Electronic databases including EMBASE, MEDLINE, and PUBMED were searched up to June 5th, 2020. Primary endpoints included effectiveness (stroke or systemic embolism [SE]) ... Read more >>

Eur J Epidemiol (European journal of epidemiology)
[2021, :]

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Fever clinics in China at the early stage of the COVID-19 pandemic.

Guowei Li, Xiaojie Wang, Ziyi Li, Xin Huang, Cheng Li, Junzhang Tian,

Int J Clin Pract (International journal of clinical practice)
[2021, 75(5):e14125]

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AnnexinA5 Might Suppress the Phenotype of Human Gastric Cancer Cells via ERK Pathway.

Xiaojie Wang, Yarui Dai, Yina Zhao, Meichuan Li, Jialu Zhang, Yunzhe Ci, Huan Wang, Xin Li,

Gastric cancer is one of the most fatal diseases around the world. However, the mechanism of the development of gastric cancer is still not clarified. In addition, the anticancer drugs have cytotoxicity with different degrees. AnnexinA5, a member of the annexin family, has a great binding ability with the membrane ... Read more >>

Front Oncol (Frontiers in oncology)
[2021, 11:665105]

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Classification of tumor subtypes leveraging constriction-channel based impedance flow cytometry and optical imaging.

Mei Jiang, Xiaojie Wang, Xiaoting Zhao, Yu Teng, Jian Chen, Junbo Wang, Wentao Yue,

As label-free biomarkers, electrical properties of single cells have been widely used for cell-type classification and cell-status evaluation. However, as intrinsic bioelectrical markers, previously reported membrane capacitance and cytoplasmic resistance (e.g., specific membrane capacitance C<sub>specific membrane</sub> and cytoplasmic conductivity σ<sub>cytoplasm</sub> ) of tumor subtypes were derived from tens of single ... Read more >>

Cytometry A (Cytometry. Part A : the journal of the International Society for Analytical Cytology)
[2021, :]

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Higher circular RNA_0015278 correlates with absence of extrathyroidal invasion, lower pathological tumor stages, and prolonged disease-free survival in papillary thyroid carcinoma patients.

Huajie Ding, Xiaojie Wang, Huiling Liu, Lei Na,

<h4>Background</h4>Circular RNA_0015278 (circ_0015278) inhibits the progression of several cancers and is greatly reduced in papillary thyroid carcinoma (PTC) tissues compared with benign thyroid lesions by microarray profiling. This study aimed to further investigate the correlation of circ_0015278 with tumor characteristics and prognosis in PTC patients.<h4>Methods</h4>Totally, 206 PTC patients who underwent ... Read more >>

J Clin Lab Anal (Journal of clinical laboratory analysis)
[2021, :e23819]

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The Influence of Internet Usage Frequency on Women's Fertility Intentions-The Mediating Effects of Gender Role Attitudes.

Pengcheng Liu, Jingjing Cao, Wenjie Nie, Xiaojie Wang, Yani Tian, Cheng Ma,

The purpose of this study is to verify the influence of internet usage frequency on women's fertility intentions and to examine the mediating effects of gender role attitudes, under the influence of internet usage frequency that affects women's fertility intentions, combined with the specific Chinese cultural context. A cross-sectional secondary ... Read more >>

Int J Environ Res Public Health (International journal of environmental research and public health)
[2021, 18(9):]

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Association between household overcrowding and depressive mood among Chinese residents.

Liu Pengcheng, Zhou Longfei, Chen Shujuan, Wang Xiaojie,

<h4>Background</h4>Recent household overcrowding has strongly affected households' mental health in China. The possible association of household overcrowding and depressive mood is not fully demonstrated in unique Chinese economic context.<h4>Objectives</h4>The aim of this study was to examine the association of household overcrowding and depressive mood among Chinese adults and to evaluate ... Read more >>

J Affect Disord (Journal of affective disorders)
[2021, 290:74-80]

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Surgeon Technical Skills, a Potential Confounder in Clinical Trials.

Xiaojie Wang, Zhifang Zheng, Pan Chi,

JAMA Surg (JAMA surgery)
[2021, 156(5):500]

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Prognostic significance of carcinoembryonic antigen combined with carbohydrate antigen 19-9 following neoadjuvant chemoradiotherapy in patients with locally advanced rectal cancer.

Zhifang Zheng, Xiaojie Wang, Xingrong Lu, Ying Huang, Pan Chi,

<h4>Aim</h4>The clinical significance of carcinoembryonic antigen (CEA) combined with carbohydrate antigen 19-9 (CA19-9) in patients with rectal cancer is not well established. The aim of this study was to determine the prognostic value of these combined tumour markers in patients with locally advanced rectal cancer (LARC) treated with neoadjuvant chemoradiotherapy ... Read more >>

Colorectal Dis (Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland)
[2021, :]

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Large-Scale Preparation of Highly Stable Recombinant Human Acidic Fibroblast Growth Factor in Escherichia coli BL21(DE3) plysS Strain.

Bingjieu Yu, Wenzhe Sun, Zhen Huang, Gang Sun, Le Li, Jiawei Gu, Mengying Zheng, Xiaokun Li, ChangJu Chun, Qi Hui, Xiaojie Wang,

In this study, the optimum human <i>aFGF</i> gene encoding haFGF<sub>135</sub> was cloned in pET3c and transferred to <i>Escherichia coli</i> BL21(DE3) plysS. To enhance the yield of fermentation and the expression level of the target protein, the fermentation parameters, including temperature, pH, dissolved oxygen, glucose concentration, ammonium chloride concentration, induction time, ... Read more >>

Front Bioeng Biotechnol (Frontiers in bioengineering and biotechnology)
[2021, 9:641505]

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CRISPR-mediated host genomic DNA damage is efficiently repaired through microhomology-mediated end joining in Zymomonas mobilis.

Xiaojie Wang, Bo Wu, Xin Sui, Zhufeng Zhang, Tao Liu, Yingjun Li, Guoquan Hu, Mingxiong He, Nan Peng,

CRISPR-Cas systems provide bacteria and archaea with adaptive immunity against mobile genetic elements (MGEs) through uptake of invader-derived spacers. De novo adaptation samples spacers from both invaders and hosts, whereas primed adaptation shows higher specificity to sample spacers from invaders in many model systems as well as in the subtype ... Read more >>

J Genet Genomics (Journal of genetics and genomics = Yi chuan xue bao)
[2021, :]

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Comparison of the AWGS and optimal stratification-defined handgrip strength thresholds for predicting survival in patients with lung cancer.

Liangyu Yin, Ling Zhang, Na Li, Jing Guo, Lijuan Liu, Xin Lin, Yang Fan, Jie Liu, Mengyuan Zhang, Feifei Chong, Xiao Chen, Chang Wang, Xu Wang, Tingting Liang, Xiangliang Liu, Li Deng, Wei Li, Mei Yang, Jiami Yu, Xiaojie Wang, Xing Liu, Shoumei Yang, Zheng Zuo, Kaitao Yuan, Miao Yu, Chunhua Song, Jiuwei Cui, Suyi Li, Zengqing Guo, Hanping Shi, Hongxia Xu, ,

<h4>Objectives</h4>Handgrip strength (HGS) is related to cancer mortality. The aim of this study was to compare the performance of the Asian Working Group for Sarcopenia 2019 (AWGS)- and optimal stratification (OS)-defined HGS thresholds for predicting the survival of patients with lung cancer (LC).<h4>Methods</h4>We performed an observational cohort study including 3230 ... Read more >>

Nutrition (Nutrition (Burbank, Los Angeles County, Calif.))
[2021, 90:111258]

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Lipidomics Reveals Glycerophospholipid Metabolism Dysregulation in the Corpus Striatum of Mice Treated with Cefepime

Xiaocong Liu, Xiaojie Wang, Qingfan Wei, Xiaowei Yang, Jiamei Zhang, Rui Xu, Haoluo Zhang, Shaomin Wang, Xuemei Wan, Linhong Jiang, Yuman He, Shu Li, Rong Chen, Yonghai Wang, Yaxing Chen, Feng Qin, Yuanyuan Chen, Yanping Dai, Hongchun Li, Ying Zhao, Huaqin Zhang, Qian Bu, Hongbo Wang, Jingwei Tian, Yinglan Zhao, Xiaobo Cen,

Cefepime exhibits a broad spectrum of antimicrobial activity and thus is widely used for severe bacterial infection. Adverse effects on the central nervous system (CNS) have been reported in the patients treated with cefepime. Current explanation for the neurobehavioral effect of cefepime mainly attributes to its ability to across blood-brain ... Read more >>

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Interferon-Lambda 1 Inhibits Staphylococcus aureus Colonization in Human Primary Keratinocytes.

Xia Wu, Yan Zhao, Ying Gu, Kun Li, Xiaojie Wang, Jianzhong Zhang,

Atopic dermatitis (AD) is a common inflammatory skin disease. <i>Staphylococcus aureus</i> (<i>S. aureus</i>) colonization in skin lesions occurs in approximately 70% of AD patients. It has been found that IFN-λ1 can inhibit the colonization of <i>S. aureus</i> in normal human nasal mucosa. IFN-λ1 can increase IL-28RA in infected human keratinocytes. ... Read more >>

Front Pharmacol (Frontiers in pharmacology)
[2021, 12:652302]

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Gonadal lipidomics profile of an ovoviviparity teleost, black rockfish, during gonadal development.

Jianshuang Li, Min Song, Haishen Wen, Ying Zhang, Yun Li, Likang Lyu, Xiaojie Wang, Xin Qi,

In order to study the variation of gonad lipidomics during reproductive cycle, black rockfish was employed as the research model in the present study. Using histology, lipidomics, and qPCR, the profile of gonad lipidomics and the expression levels of related genes during different developmental stages were detected and analyzed to ... Read more >>

Fish Physiol Biochem (Fish physiology and biochemistry)
[2021, :]

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How Do Different Nitrogen Application Levels and Irrigation Practices Impact Biological Nitrogen Fixation and its Distribution in Paddy System?

Yanhui Zhang, Tianlong Hu, Hui Wang, Haiyang Jin, Qi Liu, Zhibin Lin, Benjuan Liu, Hongtao Liu, Zhe Chen, Xinwu Lin, Xiaojie Wang, Jing Ma, Delin Sun, Xiaoli Sun, Haoye Tang, Qicheng Bei, Francesco Cherubini, Hans Peter Arp, Zubin Xie,

<h4>Background: </h4> and aims Biological nitrogen fixation (BNF) in paddy systems is impacted by nitrogen application levels and irrigation strategies, but the extents to which these factores influence BNF and its distribution in soil and rice were still largely unclear. This study investigates this influence. <h4>Methods: </h4> An airtight transparent ... Read more >>

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Hypoglycemic Efficacy of Rh-aFGF Variants in Treatment of Diabetes in ZDF Rats.

Li Zhang, Qingde Zhou, Min Chen, Xuanxin Yang, Chao Lu, Wenzhe Sun, Qi Hui, Xiaojie Wang,

Acidic fibroblast growth factor (aFGF) is a promising regulator of glucose with no adverse effects of hypoglycemia. Previous researches revealed that aFGF mediated adipose tissue remodeling and insulin sensitivity. These findings supported rh-aFGF<sub>135</sub> would be used as a new candidate for the treatment of insulin resistance and type 2 diabetes. ... Read more >>

Front Cell Dev Biol (Frontiers in cell and developmental biology)
[2021, 9:609383]

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Energy partitioning and evapotranspiration over a black locust plantation in the Yellow River Delta

Xiang Gao, Zhenyu Du, Qingshan Yang, Jinsong Zhang, Yongtao Li, Xiaojie Wang, Fengxue Gu, Weiping Hao, Zekun Yang, Dexi Liu, Jianmin Chu,

Woody plantations play a curtail role in ecological security along coastal zones. Understanding of energy partitioning and evapotranspiration (ET) over black locust plantations can reveal land-atmosphere interaction process and help us to optimize this plantation for land management in the Yellow River Delta. In this study, we investigated energy fluxes, ... Read more >>

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High-Quality Genome Resource of the Pathogen of Diaporthe (Phomopsis) phragmitis Causing Kiwifruit Soft Rot.

Xiaojie Wang, Hongjie Dong, Jianbin Lan, Yuanyuan Liu, Kuan Liang, Qi Lu, Zemin Fang, Pu Liu,

<i>Diaporthe</i> spp. are critical plant pathogens that cause wood cankers, wilt, dieback, and fruit rot in a wide variety of economic plant hosts and are regarded as one of the most acute threats faced by the kiwifruit industry worldwide. <i>Diaporthe phragmitis</i> NJD1 is a highly pathogenic isolate of soft rot ... Read more >>

Mol Plant Microbe Interact (Molecular plant-microbe interactions : MPMI)
[2021, 34(2):218-221]

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Association between serum uric acid and obesity in Chinese adults: a 9-year longitudinal data analysis.

Jie Zeng, Wayne R Lawrence, Jun Yang, Junzhang Tian, Cheng Li, Wanmin Lian, Jingjun He, Hongying Qu, Xiaojie Wang, Hongmei Liu, Guanming Li, Guowei Li,

<h4>Objectives</h4>Hyperuricaemia has been reported to be significantly associated with risk of obesity. However, previous studies on the association between serum uric acid (SUA) and body mass index (BMI) yielded conflicting results. The present study examined the relationship between SUA and obesity among Chinese adults.<h4>Methods</h4>Data were collected at Guangdong Second Provincial ... Read more >>

BMJ Open (BMJ open)
[2021, 11(2):e041919]

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