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Clinical Characteristics of 204 Children With Human Adenovirus Type 7 Pneumonia Identified by Whole Genome Sequencing in Liuzhou, China.

Xiaoli Huang, Yongsong Yi, Xiaogang Chen, Bo Wang, Yiqin Long, Jichang Chen, Chokechai Rongkavilit,

<h4>Background</h4>Clinical knowledge of human adenovirus type 7 (HAdV-7) pneumonia in children remains limited. Moreover, predictors for disease severity are largely unknown.<h4>Methods</h4>This is a retrospective study of children hospitalized at Liuzhou Maternal and Child Health Hospital, China, with HAdV-7 pneumonia in 2018-2019. Demographics, clinical characteristics, laboratory results, and imaging data were ... Read more >>

Pediatr Infect Dis J (The Pediatric infectious disease journal)
[2021, 40(2):91-95]

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Numerical Study on the Effect of Z-Warps on the Ballistic Responses of Para-Aramid 3D Angle-Interlock Fabrics.

Yingxue Yang, Xiuqin Zhang, Xiaogang Chen, Shengnan Min,

In order to achieve an efficient ballistic protection at a low weight, it is necessary to deeply explore the energy absorption mechanisms of ballistic fabric structures. In this paper, finite element (FE) yarn-level models of the designed three-dimensional (3D) angle-interlock (AI) woven fabrics and the laminated two-dimensional (2D) plain fabrics ... Read more >>

Materials (Basel) (Materials (Basel, Switzerland))
[2021, 14(3):]

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Thinner cortex is associated with psychosis onset in individuals at Clinical High Risk for Developing Psychosis: An ENIGMA Working Group mega-analysis

Maria Jalbrzikowski, Rebecca Hayes, Stephen Wood, Dorte Nordholm, Juan Zhou, Paolo Fusar-Poli, Peter Uhlhaas, Tsutomu Takahashi, Gisela Sugranyes, Yoo Bin Kwak, Daniel Mathalon, Naoyuki Katagiri, Christine Hooker, Lukasz Smigielski, Tiziano Colibazzi, Esther Via, Jinsong Tang, Shinsuke Koike, Paul Rasser, Chantal Michel, Irina Lebedeva, Wenche ten Velden Hegelstad, Camilo de la Fuente-Sandoval, James Waltz, Romina R.M. Mizrahi, Cheryl Corcoran, Franz Resch, Christian Tamnes, Shalaila Haas, Imke L.J. Lemmers-Jansen, Ingrid Agartz, Paul Allen, Ole Andreassen, Kimberley Atkinson, Peter Bachman, Inmaculada Baeza, Helen Baldwin, Cali Bartholomeusz, Kolbjørn Brønnick, Sabrina Catalano, Michael W.L. Chee, Xiaogang Chen, Kang Ik Cho, Rebecca Cooper, Vanessa Cropley, Montserrat Dolz, Bjørn Ebdrup, Adriana Fortea, Louise Glenthøj, Birte Glenthøj, Lieuwe de Haan, Holly Hamilton, Mathew Harris, Kristen Haut, Ying He, Karsten Heekeren, Andreas Heinz, Daniela Hubl, Wu Jeong Hwang, Michael Kaess, Kiyoto Kasai, Minah Kim, Jochen Kindler, Mallory Klaunig, Tina Kristensen, Jun Soo Kwon, Stephen Lawrie, Jimmy Lee, Pablo León-Ortiz, Ashleigh Lin, Rachel Loewy, Xiaoqian Ma, Daniel Mathalon, Patrick McGorry, Philip McGuire, Masafumi Mizuno, Paul Møller, Toma Moncada-Habib, Daniel Munoz-Samons, Barnaby Nelson, Takahiro Nemoto, Merete Nordentoft, Maria Omelchenko, Ketil Oppedal, Lijun Ouyang, Christos Pantelis, Jose Pariente, Jayachandra Raghava, Francisco Reyes-Madrigal, Brian Roach, Jan Røssberg, Wulf Rössler, Dean Salisbury, Daiki Sasabayashi, Ulrich Schall, Jason Schiffman, Florian Schlagenhauf, Andre Schmidt, Mikkel Sørensen, Michio Suzuki, Anastasia Theodoridou, Alexander Tomyshev, Jordina Tor, Tor Vaernes, Dennis Velakoulis, Gloria Venegoni, Sophia Vinogradov, Christina Wenneberg, Lars Westlye, Hidenori Yamasue, Liu Yuan, Alison Yung, Thérèse A.M.J. van Amelsvoort, Jessica Turner, Theo G.M. van Erp, Paul Thompson, Dennis Hernaus, Koppel, Borgwardt,

<h4>Importance</h4> The ENIGMA clinical high risk for psychosis (CHR) initiative, the largest pooled CHR-neuroimaging sample to date, aims to discover robust neurobiological markers of psychosis risk in a sample with known heterogeneous outcomes. <h4>Objective</h4> We investigated baseline structural neuroimaging differences between CHR subjects and healthy controls (HC), and between CHR ... Read more >>

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Utility of radium quartet for evaluating porewater-derived carbon to a saltmarsh nearshore water: Implications for blue carbon export.

Jianan Liu, Xueqing Yu, Xiaogang Chen, Jinzhou Du, Fenfen Zhang,

Saltmarshes are global hotspots of carbon sequestration and storage and are known as effective blue carbon ecosystems. However, the role of porewater exchange in saltmarshes as a source of carbon to the nearshore waters is still poorly constrained. Herein, we examined the radium quartet, dissolved inorganic (DIC) and organic (DOC) ... Read more >>

Sci Total Environ (The Science of the total environment)
[2020, 764:144238]

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Novel Risk Loci Associated With Genetic Risk for Bipolar Disorder Among Han Chinese Individuals: A Genome-Wide Association Study and Meta-analysis.

Hui-Juan Li, Chen Zhang, Li Hui, Dong-Sheng Zhou, Yi Li, Chu-Yi Zhang, Chuang Wang, Lu Wang, Wenqiang Li, Yongfeng Yang, Na Qu, Jinsong Tang, Ying He, Jun Zhou, Zihao Yang, Xingxing Li, Jun Cai, Lu Yang, Jun Chen, Weixing Fan, Wei Tang, Wenxin Tang, Qiu-Fang Jia, Weiqing Liu, Chuanjun Zhuo, Xueqin Song, Fang Liu, Yan Bai, Bao-Liang Zhong, Shu-Fang Zhang, Jing Chen, Bin Xia, Luxian Lv, Zhongchun Liu, Shaohua Hu, Xiao-Yan Li, Jie-Wei Liu, Xin Cai, Yong-Gang Yao, Yuyanan Zhang, Hao Yan, Suhua Chang, Jing-Ping Zhao, Wei-Hua Yue, Xiong-Jian Luo, Xiaogang Chen, Xiao Xiao, Yiru Fang, Ming Li, ,

<h4>Importance</h4>The genetic basis of bipolar disorder (BD) in Han Chinese individuals is not fully understood.<h4>Objective</h4>To explore the genetic basis of BD in the Han Chinese population.<h4>Design, setting, and participants</h4>A genome-wide association study (GWAS), followed by independent replication, was conducted to identify BD risk loci in Han Chinese individuals. Individuals with ... Read more >>

JAMA Psychiatry (JAMA psychiatry)
[2020, :]

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Land use and episodic rainfall as drivers of nitrogen exports in subtropical rivers: Insights from δ15N-NO3-, δ18O-NO3- and 222Rn.

Praktan D Wadnerkar, Luke Andrews, Wei Wen Wong, Xiaogang Chen, Rogger E Correa, Shane White, Perran L M Cook, Christian J Sanders, Isaac R Santos,

Ongoing land-use intensification in subtropical catchments is expected to release more inorganic nitrogen to downstream coastal waters similar to historical changes in temperate ecosystems. Here, we examined spatial and temporal drivers of stream nitrogen loads across a subtropical land-use gradient using the isotopic compositions of nitrate (NO<sub>3</sub><sup>-</sup>-N) and radon (<sup>222</sup>Rn), ... Read more >>

Sci Total Environ (The Science of the total environment)
[2021, 758:143669]

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Combination of Augmented Reality Based Brain-Computer Interface and Computer Vision for High-Level Control of A Robotic Arm.

Xiaogang Chen, Xiaoshan Huang, Yijun Wang, Xiaorong Gao,

Recent advances in robotics, neuroscience, and signal processing make it possible to operate a robot through electroencephalography (EEG)-based brain-computer interface (BCI). Although some successful attempts have been made in recent years, the practicality of the entire system still has much room for improvement. The present study designed and realized a ... Read more >>

IEEE Trans Neural Syst Rehabil Eng (IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society)
[2020, PP:]

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Anterior Cingulate Cortex Glutamate Levels Are Related to Response to Initial Antipsychotic Treatment in Drug-Naive First-Episode Schizophrenia Patients.

Jinguang Li, Honghong Ren, Ying He, ZongChang Li, Xiaoqian Ma, Liu Yuan, Lijun Ouyang, Jun Zhou, Dong Wang, Chunwang Li, Xiaogang Chen, Hongying Han, Jinsong Tang,

The glutamatergic system has previously been shown to be involved in the pathophysiology of schizophrenia and the mechanisms of action of antipsychotic treatment. The present study aimed to investigate the relationship between the levels of glutamate (Glu) or Glu/total creatine (Glu/Cr+PCr) in the anterior cingulate cortex (ACC) and psychiatric symptoms ... Read more >>

Front Psychiatry (Frontiers in psychiatry)
[2020, 11:553269]

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Effect of Food on the Pharmacokinetic and Pharmacodynamic Profiles of Hetrombopag in Healthy Volunteers.

Zhenlei Wang, Xiaogang Chen, Aiwei Li, Li Chen, Yongsheng Wang, Li Zheng,

<h4>Purpose</h4>Hetrombopag, a novel, oral small molecule thrombopoietin receptor agonist, exhibits an obvious thrombocytopoietic effect with good safety. Hetrombopag is currently under clinical development for the treatment of chronic idiopathic thrombocytopenic purpura (ITP). The objectives of this study were to assess the effect of high-fat and high-calorie food on the pharmacokinetic ... Read more >>

Clin Ther (Clinical therapeutics)
[2020, 42(12):2280-2288]

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Bacterial-derived nutrient and carbon source-sink behaviors in a sandy beach subterranean estuary.

Xiaogang Chen, Qi Ye, Christian J Sanders, Jinzhou Du, Jing Zhang,

Microbial communities in subterranean estuaries play important roles in the biogeochemical cycle. However, the microorganisms associated with biogeochemical behaviors in subterranean estuaries have received little attention. Here, the bacterial communities were compared between the fresh and saline groundwater in a subterranean estuary. Correlation analysis between bacterial groups and salinity indicated ... Read more >>

Mar Pollut Bull (Marine pollution bulletin)
[2020, 160:111570]

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Acupoint application for rotavirus diarrhea in infants and children: A protocol for systematic review and meta analysis.

Shaodan Sun, Xiaojie Lin, Yang Yang, Jingtu Cen, Fei Luo, Xiaogang Chen,

<h4>Background</h4>Diarrheal disease currently claims the lives of approximately 500,000 children each year. Rotaviruses are the pathogens primarily responsible for more severe cases and more than one-third of diarrhea-associated deaths in children under 5 years old globally. At present, commonly used drug therapies for rotavirus diarrhea in Western medicine, such as ... Read more >>

Medicine (Baltimore) (Medicine)
[2020, 99(38):e22227]

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Circulating Brain-Derived Neurotrophic Factor, Antioxidant Enzymes Activities, and Mitochondrial DNA in Bipolar Disorder: An Exploratory Report.

Dong Wang, Hong Li, Xiangdong Du, Jun Zhou, Liu Yuan, Honghong Ren, Xiaonan Yang, Guangya Zhang, Xiaogang Chen,

<h4>Aim</h4>Accumulated evidence indicates that neurotrophin deregulations, oxidative stress injury, and mitochondrial dysfunction have been involved in bipolar disorder (BD); however, their real roles in BD are unclear. Investing the possible interaction between three systems is worthwhile understanding this complex process.<h4>Methods</h4>We measured plasma brain-derived neurotrophic factor (BDNF) level, leukocytes mitochondrial DNA ... Read more >>

Front Psychiatry (Frontiers in psychiatry)
[2020, 11:514658]

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Comparative study between follicular unit transplantation with intact and non-intact hair bulb in treatment for stable vitiligo.

Yuchong Chen, Jianna Yan, Xuewen Chen, Leimeng Gan, Min Song, Jue Wang, Hongxia Shen, Hao Luo, Long Jiang, Xi Luo, Xiaogang Chen, Yichen Tang,

<h4>Objective</h4>To compare the cosmetic efficacy of the transplantation of follicles with intact and non-intact hair bulbs in the treatment for vitiligo.<h4>Methods</h4>The single-hair follicle units with intact hair bulbs and un-intact hair bulbs were transplanted into the skin of vitiligo. The diameters of regrowing hair shafts and repigmentation of implanted follicles ... Read more >>

J Dermatolog Treat (The Journal of dermatological treatment)
[2020, :1-4]

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Independent replications and integrative analyses confirm TRANK1 as a susceptibility gene for bipolar disorder.

Wenqiang Li, Xin Cai, Hui-Juan Li, Meng Song, Chu-Yi Zhang, Yongfeng Yang, Luwen Zhang, Lijuan Zhao, Weipeng Liu, Lu Wang, Minglong Shao, Yan Zhang, Chen Zhang, Jun Cai, Dong-Sheng Zhou, Xingxing Li, Li Hui, Qiu-Fang Jia, Na Qu, Bao-Liang Zhong, Shu-Fang Zhang, Jing Chen, Bin Xia, Yi Li, Xueqin Song, Weixing Fan, Wei Tang, Wenxin Tang, Jinsong Tang, Xiaogang Chen, Weihua Yue, Dai Zhang, Yiru Fang, Xiao Xiao, Ming Li, Luxian Lv, Hong Chang,

Genetic analyses for bipolar disorder (BD) have achieved prominent success in Europeans in recent years, whereas its genetic basis in other populations remains relatively less understood. We herein report that the leading risk locus for BD in European genome-wide association studies (GWAS), the single-nucleotide polymorphism (SNP) rs9834970 near TRANK1 at ... Read more >>

Neuropsychopharmacology (Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology)
[2020, :]

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Optimizing a dual-frequency and phase modulation method for SSVEP-based BCIs.

Liyan Liang, Jiajun Lin, Chen Yang, Yijun Wang, Xiaogang Chen, Shangkai Gao, Xiaorong Gao,

<h4>Objective</h4>The design of the stimulation paradigm plays an important role in steady-state visual evoked potential (SSVEP)-based brain-computer interface (BCI) studies. Among various stimulation designs, the dual-frequency paradigm in which two frequencies are used to encode one target is of importance and interest. However, because the number of possible frequency combinations ... Read more >>

J Neural Eng (Journal of neural engineering)
[2020, 17(4):046026]

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Cricumscribed and Multiple Hidroacanthoma Simplex.

Hao Luo, Wei Zhao, Fei Wu, Long Jiang, Jianna Yan, Yuchong Chen, Xiaogang Chen, Liang Li, Xiaojing Liu, Yichen Tang, Yeqiang Liu,

Indian J Dermatol (Indian journal of dermatology)
[2020, 65(4):318-319]

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BETA: A Large Benchmark Database Toward SSVEP-BCI Application.

Bingchuan Liu, Xiaoshan Huang, Yijun Wang, Xiaogang Chen, Xiaorong Gao,

The brain-computer interface (BCI) provides an alternative means to communicate and it has sparked growing interest in the past two decades. Specifically, for Steady-State Visual Evoked Potential (SSVEP) based BCI, marked improvement has been made in the frequency recognition method and data sharing. However, the number of pubic databases is ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2020, 14:627]

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[Indoor simulation training system for brain-controlled wheelchair based on steady-state visual evoked potentials].

Jinhai Wang, Kangning Wang, Xiaogang Chen, Huiquan Wang, Shengpu Xu, Ming Liu,

Brain-controlled wheelchair (BCW) is one of the important applications of brain-computer interface (BCI) technology. The present research shows that simulation control training is of great significance for the application of BCW. In order to improve the BCW control ability of users and promote the application of BCW under the condition ... Read more >>

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi (Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi)
[2020, 37(3):502-511]

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Synergistic antifibrotic effects of miR-451 with miR-185 partly by co-targeting EphB2 on hepatic stellate cells.

Xiaogang Chen, Dan Zhang, Yi Wang, Ke Chen, Limeng Zhao, Yating Xu, Hulin Jiang, Shuzhen Wang,

Liver fibrosis is a global health problem currently without clinically approved drugs. It is characterized by the excessive accumulation of extracellular matrix (ECM) mainly produced by activated hepatic stellate cells (HSCs). Uncovering the mechanisms underlying the fibrogenic responses in HSCs may have profound translational implications. Erythropoietin-producing hepatocellular receptor B2 (EphB2) ... Read more >>

Cell Death Dis (Cell death & disease)
[2020, 11(5):402]

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Exposure time determines the protective effect of Trichinella spiralis on experimental colitis.

Wenxiao Zheng, Zhenrong Ma, Xi Sun, Yehong Huang, Bin Lu, Xiaogang Chen, Xiang Xue, Xuexian Yang, Xiang Wu,

Several studies demonstrate the protective effect of Trichinella spiralis (T. spiralis) on autoimmune diseases, however the optimal exposure time remains unexplored. This study aimed to determine whether pre-exposure of mice to T. spiralis conferred greater protection than introduction of the parasite in the acute phase of experimental colitis. We compared ... Read more >>

Microb Pathog (Microbial pathogenesis)
[2020, 147:104263]

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A functional missense variant in ITIH3 affects protein expression and neurodevelopment and confers schizophrenia risk in the Han Chinese population.

Kaiqin Li, Yifan Li, Junyang Wang, Yongxia Huo, Di Huang, Shiwu Li, Jiewei Liu, Xiaoyan Li, Rong Liu, Xiaogang Chen, Yong-Gang Yao, Ceshi Chen, Xiao Xiao, Ming Li, Xiong-Jian Luo,

The Psychiatric Genomics Consortium (PGC) has recently identified 10 potential functional coding variants for schizophrenia. However, how these coding variants confer schizophrenia risk remains largely unknown. Here, we investigate the associations between eight potential functional coding variants identified by PGC and schizophrenia in a large Han Chinese sample (n = 4022 cases ... Read more >>

J Genet Genomics (Journal of genetics and genomics = Yi chuan xue bao)
[2020, 47(5):233-248]

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Methylation-mediated miR-214 regulates proliferation and drug sensitivity of renal cell carcinoma cells through targeting LIVIN.

Hao Xu, Shangjun Wu, Xin Shen, Zhan Shi, Ding Wu, Yuan Yuan, Wei Jiang, Qianliang Wang, Qin Ke, Qing Mao, Xianlong Li, Yong Liu, Pingcheng Yuan, Qinghan Zhang, Enying Huang, Xiaogang Chen,

LIVIN, a member of the inhibitor of apoptosis proteins (IAPs), is reported playing important roles in the development and progression of multiple human cancers. However, its underlined mechanisms in human renal cell carcinoma (RCC) are still needed to be clarified. In the present study, we reported that inhibition of miR-214 ... Read more >>

J Cell Mol Med (Journal of cellular and molecular medicine)
[2020, 24(11):6410-6425]

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A simple modified surgical technique combined with tissue adhesive for steatocystoma multiplex.

Long Jiang, Jianna Yan, Xiaogang Chen, Yuchong Chen, Yichen Tang,

<h4>Background</h4>Steatocystoma multiplex (SM) is a disorder of the pilosebaceous unit characterized by multiple sebum-containing dermal cysts. Psychological distress of patients is always derived from these undesirable lesions. Although various treatments have been attempted to improve cosmetic outcomes, no optimal treatment strategy has been established to date..<h4>Aims</h4>To provide a facile and ... Read more >>

J Cosmet Dermatol (Journal of cosmetic dermatology)
[2021, 20(1):218-221]

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A novel training-free recognition method for SSVEP-based BCIs using dynamic window strategy.

Yonghao Chen, Chen Yang, Xiaogang Chen, Yijun Wang, Xiaorong Gao,

OBJECTIVE:Filter bank canonical correlation analysis (FBCCA) is a widely-used classification approach implemented in steady-state visual evoked potential (SSVEP)-based brain-computer interfaces (BCIs). However, conventional detection algorithms for SSVEP recognition problems, including the FBCCA, were usually based on 'fixed window' strategy. That's to say, these algorithms always analyze data with fixed length. ... Read more >>

J Neural Eng (Journal of neural engineering)
[2020, :]

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Optofluidic microbubble Fabry-Pérot cavity.

Xiaogang Chen, Xuyang Zhao, Zhihe Guo, Liang Fu, Qijing Lu, Shusen Xie, Xiang Wu,

An optofluidic microbubble Fabry-Pérot (OMBFP) cavity was investigated. In contrast to plane-plane FP (PPFP) cavities, the optical mode confinement and stability in an OMBFP were significantly enhanced. The optical properties of the OMBFP cavity, including the quality (Q) factor, effective mode area, mode distribution as a function of the core ... Read more >>

Opt Express (Optics express)
[2020, 28(10):15161-15172]

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