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Sensitivity of Puccinia graminis f. sp. tritici Isolates From China to Triadimefon and Cross-Resistance Against Diverse Fungicides.

Xianxin Wu, Qiang Bian, Qiujun Lin, Qian Sun, Xinyu Ni, Xiaofeng Xu, Yongchun Qiu, Yuanhu Xuan, Yuanyin Cao, Tianya Li,

Wheat stem rust caused by Puccinia graminis f. sp. tritici is an important wheat disease with sudden and devastating characteristics. The appearance and spread of new P. graminis f. sp. tritici races (Ug99, TKTTF, and TTTTF) have once again renewed the interest in the prevention and control of wheat stem ... Read more >>

Plant Dis. (Plant disease)
[2020, :PDIS01200009RE]

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Chromosomal aberration arises during somatic reprogramming to pluripotent stem cells

Xinyu Liu, Kang Zheng, Xiaofeng Zhao, Xiaofeng Xu, Aifeng Yang, Min Yi, Huaping Tao, Binghua Xie, Mengsheng Qiu, Junlin Yang,

Abstract Background: Reprogramming somatic cells to induced pluripotent stem cells (iPSCs) has opened new therapeutic possibilities. However, karyotypic abnormalities detected in iPSCs compromised their utility, especially chromosomal aberrations found at early passages raised serious safety concerns. The mechanism underlying the chromosomal abnormality in early-passage iPSCs is not known. Methods: Human ... Read more >>

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[Application of Raman Spectroscopy in the Diagnosis of Oral Cancer].

Zhihui Zhu, Fanhao Meng, Jiabin Xia, Xiaofeng Xu, Yang Hu, Aijin Zhang, Tao Zhang,

Oral cancer is a common and deadly malignancy.While multidisciplinary treatment(mainly surgery)has been applied in the treatment of cancer treatment,early diagnosis and complete removal of the primary lesion are essential for a better prognosis.Raman spectroscopy is an optical technique that detects inelastic scattered light generated by the interaction of light and ... Read more >>

Zhongguo Yi Xue Ke Xue Yuan Xue Bao (Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae)
[2020, 42(3):399-404]

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microRNA-216a-5p inhibits the development of gastric cancer through target combination with TCTN1.

Xiaofeng Xu, Feng Gao, Jianjiang Wang, Cong Long, Lan Tao, Li Ding, Yong Ji,

BACKGROUND:We aimed at investigating microRNA-216a-5p expression in gastric cancer (GC) tissues and further exploring whether microRNA-216a-5p suppresses GC progression through interacting with TCTN1. METHODS:microRNA-216a-5p expression in 60 pairs of GC tissues and adjacent ones was studied by quantitative real-time polymerase chain reaction (qRT-PCR) analysis, and the relationship between microRNA-216a-5p and ... Read more >>

Minerva Med. (Minerva medica)
[2020, :]

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Rising vegetation activity dominates growing water use efficiency in the Asian permafrost region from 1900 to 2100.

Fenghui Yuan, Jianzhao Liu, Yunjiang Zuo, Ziyu Guo, Nannan Wang, Changchun Song, Zongming Wang, Li Sun, Yuedong Guo, Yanyu Song, Dehua Mao, Feifan Xu, Xiaofeng Xu,

Permafrost play an important role in regulating global climate system. We analyzed the gross primary productivity (GPP), net primary productivity (NPP), and evapotranspiration (ET) derived from MODIS and three earth system models participated in the Coupled Model Inter-comparison Project Phase 6 (CMIP6) in the Asian permafrost region. The water use ... Read more >>

Sci. Total Environ. (The Science of the total environment)
[2020, 736:139587]

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Dexmedetomidine for prevention of propofol injection pain upon induction of anesthesia: a meta-analysis.

Liting Ji, Weihua Sun, Yunping Lan, Changxing Xia, Gongmin Yu, Qinghua Wu, Shufen Yang, Xiaofeng Xu,

PURPOSE:Propofol injection pain is a very common problem during the induction of general anesthesia. The purpose of this review is to evaluate the effectiveness of dexmedetomidine for the prevention of propofol injection pain so as to provide evidence for future clinical applications. METHODS:PubMed, Embase, Cochrane library, and Google Scholar databases ... Read more >>

Eur. J. Clin. Pharmacol. (European journal of clinical pharmacology)
[2020, :]

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Clinical characteristics of imported and second-generation COVID-19 cases outside Wuhan, China: A multicenter retrospective study

Puyu Shi, Guoxia Ren, Jun Yang, Zhiqiang Li, Shujiao Deng, Miao Li, Shasha Wang, Xiaofeng Xu, Fuping Chen, Yuanjun Li, Chunyan Li, Xiaohua Yang, Zhaofeng Xie, Zhengxia Wu, Chen Mingwei,

Abstract Background: The mortality of COVID-19 differs between countries and regions. By now, reports on COVID-19 are largely focused on first-generation cases. This study aimed to clarify the clinical characteristics of imported and second-generation cases. Methods : This retrospective, multicenter cohort study included 134 confirmed COVID-19 cases from 9 cities ... Read more >>

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Triple therapy combined with ventriculoperitoneal shunts can improve neurological function and shorten hospitalization time in non-HIV cryptococcal meningitis patients with increased intracranial pressure

Min Li, Jia Liu, Xuhui Deng, Qingzhou Gan, Yijie Wang, Xiaofeng Xu, Ying Jiang, Fuhua Peng,

Abstract Background Raised intracranial pressure (ICP) and insufficient antifungal regimens, are the two main factors result to unsatisfactory outcomes in non-HIV cryptococcal meningitis (CM) patients. In this study, we try to discuss that whether triple therapy of amphotericin B (AmB), fluconazole (Flu), 5-flucytosine (5-FC) plus ventriculoperitoneal shunts (VPS) ... Read more >>

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A novel hemizygous loss-of-function mutation in ADGRG2 causes male infertility with congenital bilateral absence of the vas deferens.

Huan Wu, Yang Gao, Cong Ma, Qunshan Shen, Jiajia Wang, Mingrong Lv, Chunyu Liu, Huiru Cheng, Fuxi Zhu, Shixiong Tian, Nagwa Elshewy, Xiaoqing Ni, Qing Tan, Xiaofeng Xu, Ping Zhou, Zhaolian Wei, Feng Zhang, Xiaojin He, Yunxia Cao,

PURPOSE:Cystic fibrosis transmembrane conductance regulator (CFTR) and adhesion G protein-coupled receptor G2 (ADGRG2) have been identified as the main pathogenic genes in congenital bilateral absence of the vas deferens (CBAVD), which is an important cause of obstructive azoospermia. This study aimed to identify the disease-causing gene in two brothers with ... Read more >>

J. Assist. Reprod. Genet. (Journal of Assisted Reproduction and Genetics)
[2020, 37(6):1421-1429]

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Triple therapy combined with ventriculoperitoneal shunts can improve neurological function and shorten hospitalization time in non-HIV cryptococcal meningitis patients with increased intracranial pressure

Min Li, Jia Liu, Xuhui Deng, Qingzhou Gan, Yijie Wang, Xiaofeng Xu, Ying Jiang, Fuhua Peng,

Abstract Background: Raised intracranial pressure (ICP) and insufficient antifungal regimens, are the two main factors result to unsatisfactory outcomes in non-HIV cryptococcal meningitis (CM) patients. In this study, we try to discuss that whether triple therapy of amphotericin B (AmB), fluconazole (Flu), 5-flucytosine (5-FC) plus ventriculoperitoneal shunts (VPS) is superior ... Read more >>

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Highly Conductive PDMS Composite Mechanically Enhanced with 3D-Graphene Network for High-Performance EMI Shielding Application.

Dongyi Ao, Yongliang Tang, Xiaofeng Xu, Xia Xiang, Jingxia Yu, Sean Li, Xiaotao Zu,

A highly conductive three-dimensional (3D) graphene network (GN) was fabricated by chemical vapor deposition on a 3D nickel fiber network and subsequent etching process. Then a lightweight and flexible polydimethylsiloxane (PDMS)/GN composite was prepared by a vacuum infiltration method by using the graphene network as a template. The composite showed ... Read more >>

Nanomaterials (Basel) (Nanomaterials (Basel, Switzerland))
[2020, 10(4):]

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Clinical characteristics of imported and second-generation COVID-19 cases outside Wuhan, China: A multicenter retrospective study

Puyu Shi, Guoxia Ren, Jun Yang, Zhiqiang Li, Shujiao Deng, Miao Li, Shasha Wang, Xiaofeng Xu, Fuping Chen, Yuanjun Li, Chunyan Li, Xiaohua Yang, Zhaofeng Xie, Zhengxia Wu, Mingwei Chen,

Background The mortality of COVID-19 differs between countries and regions. By now, reports on COVID-19 are largely focused on first-generation cases. This study aimed to clarify the clinical characteristics of imported and second-generation cases. Methods This retrospective, multicenter cohort study included 134 confirmed COVID-19 cases from 9 cities outside Wuhan. ... Read more >>

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Mapping the Architecture of Ferret Brains at Single-Cell Resolution.

Ben Long, Tao Jiang, Jianmin Zhang, Siqi Chen, Xueyan Jia, Xiaofeng Xu, Qingming Luo, Hui Gong, Anan Li, Xiangning Li,

Mapping the cytoarchitecture of the whole brain can reveal the organizational logic of neural systems. However, this remains a significant challenge, especially for gyrencephalic brains with a large volume. Here we propose an integrated pipeline for generating a cytoarchitectonic atlas with single-cell resolution of the whole brain. To analyze a ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2020, 14:322]

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Analysis of microRNA expression profiles dynamic in different life stages of Haemaphysalis longicornis ticks by deep sequencing of small RNA libraries.

Wenge Liu, Junhui Guo, Jin Luo, Qiaoyun Ren, Ze Chen, Zhiqiang Qu, Zegong Wu, Jun Ni, Xiaofeng Xu, Muhammad Rashid, Jianxun Luo, Hong Yin, Zengqi Yang, Guangyuan Liu,

The three-host tick Haemaphysalis longicornis is an obligate blood-sucking ectoparasite. In life-stage transitions, microRNAs (miRNAs) show a variety of expression changes. To investigate these changes, deep sequencing technology was applied to identify the conserved and potentially novel miRNAs expressed during the different life stages of H. longicornis. Total RNA from ... Read more >>

Ticks Tick Borne Dis (Ticks and tick-borne diseases)
[2020, 11(4):101427]

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Profiles of narcissism and self-esteem associated with comprehensive mental health in adolescents.

Xiaofeng Xu, E Scott Huebner, Lili Tian,

INTRODUCTION:This study firstly aimed to identify different profiles of narcissism and self-esteem in adolescents using latent profile analysis (LPA). A secondary aim was to examine associations between the identified profiles and subsequent measures of comprehensive mental health. METHODS:Chinese adolescents (N = 1009, 50.8%girls, Mage = 12.99, SD = 0.66) completed a packet of measures on two ... Read more >>

J Adolesc (Journal of adolescence)
[2020, 80:275-287]

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Superconductivity enhancement in FeSe/SrTiO3: a review from the perspective of electron-phonon coupling.

Xiaofeng Xu, Shuyuan Zhang, Xuetao Zhu, Jiandong Guo,

Single-layer FeSe films grown on SrTiO3, with the highest superconducting transition temperature (T C) among all the iron-based superconductors, serves as an ideal platform for studying the microscopic mechanisms of high-T C superconductivity. The significant role of interfacial coupling has been widely recognized, while the precise nature of the T ... Read more >>

J Phys Condens Matter (Journal of physics. Condensed matter : an Institute of Physics journal)
[2020, 32(34):343003]

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Full-length genome sequence of segmented RNA virus from ticks was obtained using small RNA sequencing data

Xiaofeng Xu, Jinlong Bei, Yibo Xuan, Jianyuan Chen, Defu Chen, Stephen Barker, Samuel Kelava, Bingjun He, Shan Gao, Ze Chen,

Abstract In 2014, A novel tick-borne virus of the genus Flavivirus was first reported from the Mogiana region in Brazil. This virus was named the Mogiana tick virus (MGTV). Later, MGTV was also named as Jingmen tick virus (JMTV), Kindia tick virus (KDTV), Guangxi tick virus (GXTV) etc. In the ... Read more >>

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Automated Brain Region Segmentation for Single Cell Resolution Histological Images Based on Markov Random Field.

Xiaofeng Xu, Yue Guan, Hui Gong, Zhao Feng, Wenjuan Shi, Anan Li, Miao Ren, Jing Yuan, Qingming Luo,

The brain consists of massive regions with different functions and the precise delineation of brain region boundaries is important for brain region identification and atlas illustration. In this paper we propose a hierarchical Markov random field (MRF) model for brain region segmentation, where a MRF is applied to the downsampled ... Read more >>

Neuroinformatics (Neuroinformatics)
[2020, 18(2):181-197]

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Destruction in maternal-fetal interface of URSA patients via the increase of the HMGB1-RAGE/TLR2/TLR4-NF-κB signaling pathway.

Huijuan Zou, Jiaqian Yin, Zhiguo Zhang, Huifen Xiang, Jing Wang, Damin Zhu, Xiaofeng Xu, Yunxia Cao,

AIMS:HMGB1 has been reported to play a crucial role in the physiological and pathophysiological responses during pregnancy. However, it is still unknown whether excessively expressed HMGB1 at the maternal-fetal interface related to Unexplained Recurrent Spontaneous Abortion (URSA). This study was designed to investigate the local capability of HMGB1 in the ... Read more >>

Life Sci. (Life sciences)
[2020, 250:117543]

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Novel conjugates of endoperoxide and 4-anilinoquinazoline induce myeloma cell apoptosis by inhibiting the IGF1-R/AKT/mTOR signaling pathway.

Yujia Xu, Kun Zeng, Xiaoge Wang, Jieyu Zhang, Biyin Cao, Zubin Zhang, Chunhua Qiao, Xiaofeng Xu, Qi Wang, Yuanying Zeng, Xinliang Mao,

4-anilinoquinazoline-containing inhibitors of the epidermal growth factor receptor (EGFR) are widely used in non-small cell lung cancer patients with mutated EGFR, but they are less effective in multiple myeloma (MM), a fatal malignancy derived from plasma cells. The present study designed a series of novel compounds by conjugating a peroxide ... Read more >>

Biosci Trends (Bioscience trends)
[2020, 14(2):96-103]

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The alterations of mitochondrial DNA in coronary heart disease.

Haochang Hu, Ying Lin, Xiaofeng Xu, Shaoyi Lin, Xiaomin Chen, Shuangshuang Wang,

Coronary heart disease (CHD) is the major cause of death in modern society. CHD is characterized by atherosclerosis, which could lead to vascular cavity stenosis or obstruction, resulting in ischemic cardiac conditions such as angina and myocardial infarction. In terms of the mitochondrion, the main function is to produce adenosine ... Read more >>

Exp. Mol. Pathol. (Experimental and molecular pathology)
[2020, 114:104412]

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Phosphorus alleviation of nitrogen-suppressed methane sink in global grasslands.

Lihua Zhang, Fenghui Yuan, Junhong Bai, Hongtao Duan, Xueying Gu, Longyu Hou, Yao Huang, Mingan Yang, Jin-Sheng He, Zhenhua Zhang, Lijun Yu, Changchun Song, David A Lipson, Donatella Zona, Walter Oechel, Ivan A Janssens, Xiaofeng Xu,

Grassland ecosystems account for more than 10% of the global CH4 sink in soils. A 4-year field experiment found that addition of P alone did not affect CH4 uptake and experimental addition of N alone significantly suppressed CH4 uptake, whereas concurrent N and P additions suppressed CH4 uptake to a ... Read more >>

Ecol. Lett. (Ecology letters)
[2020, 23(5):821-830]

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ADAMTS13 ameliorates inflammatory responses in experimental autoimmune encephalomyelitis.

Kaili Lu, Lan Liu, Xiaofeng Xu, Fei Zhao, Jiangshan Deng, Xin Tang, Xiuzhe Wang, Bing-Qiao Zhao, Xiaojie Zhang, Yuwu Zhao,

BACKGROUND:ADAMTS13 (a disintegrin and metalloprotease with a thrombospondin type 1 motif, member 13) plays a vital role in preventing microvascular thrombosis and inflammation. Reduced ADAMTS13 levels in plasma have been detected in multiple sclerosis (MS) patients. In the present study, we have determined the role of ADAMTS13 in the disease ... Read more >>

J Neuroinflammation (Journal of Neuroinflammation)
[2020, 17(1):67]

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Effects of domestic sewage from different sources on greenhouse gas emission and related microorganisms in straw-returning paddy fields.

Mengyao Li, Lihong Xue, Beibei Zhou, Jingjing Duan, Zhu He, Xugang Wang, Xiaofeng Xu, Linzhang Yang,

Reusing domestic sewage for crop irrigation is a promising practice, particularly in developing countries, since it is a substitute for chemical fertilizer and reduces water contamination. More attention was paid to the effect of sewage irrigation on crop yield and soil nutrients, but little attention was paid to greenhouse gas ... Read more >>

Sci. Total Environ. (The Science of the total environment)
[2020, 718:137407]

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Pressure engineering of the Dirac fermions in quasi-one-dimensional Tl2Mo6Se6.

Ziwan Song, Bin Li, Chunqiang Xu, Sixuan Wu, Bin Qian, Tong Chen, Pabitra K Biswas, Xiaofeng Xu, Jian Sun,

Topological band dispersions other than the standard Dirac or Weyl fermions have garnered the increasing interest in materials science. Among them, the cubic Dirac fermions were recently proposed in the family of quasi-one-dimensional (q-1D) conductors A2Mo6X6 (A  =  Na, K, In, Tl; X  =  S, Se, Te), where the band crossing is characterized by ... Read more >>

J Phys Condens Matter (Journal of physics. Condensed matter : an Institute of Physics journal)
[2020, 32(21):215402]

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