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Multifunctional properties of a star-shaped triphenylamine-benzene-1,3,5-tricarbohydrazide fluorescent molecule containing multiple flexible chains.

Xin Feng, Yating Chen, Yunxiang Lei, Yunbing Zhou, Wenxia Gao, Miaochang Liu, Xiaobo Huang, Huayue Wu,

A star-shaped triphenylamine-benzene-1,3,5-tricarbohydrazide molecule with a twisted molecular conformation was found to display amazing multifunctional optical properties. The design of peripheral triphenylamine units and a central benzene connected with hydrazide groups leads to the formation of rare polymorphic properties in the presence of multiple flexible chains. Two polymorphs with different ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2020, 56(88):13638-13641]

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Evolution Over Time of Ventilatory Management and Outcome of Patients With Neurologic Disease.

Eva E Tejerina, Paolo Pelosi, Chiara Robba, Oscar Peñuelas, Alfonso Muriel, Deisy Barrios, Fernando Frutos-Vivar, Konstantinos Raymondos, Bin Du, Arnaud W Thille, Fernando Ríos, Marco González, Lorenzo Del-Sorbo, Maria Del Carmen Marín, Bruno Valle Pinheiro, Marco Antonio Soares, Nicolas Nin, Salvatore M Maggiore, Andrew Bersten, Pravin Amin, Nahit Cakar, Gee Young Suh, Fekri Abroug, Manuel Jibaja, Dimitros Matamis, Amine Ali Zeggwagh, Yuda Sutherasan, Antonio Anzueto, Andrés Esteban, ,

<h4>Objectives</h4>To describe the changes in ventilator management over time in patients with neurologic disease at ICU admission and to estimate factors associated with 28-day hospital mortality.<h4>Design</h4>Secondary analysis of three prospective, observational, multicenter studies.<h4>Setting</h4>Cohort studies conducted in 2004, 2010, and 2016.<h4>Patients</h4>Adult patients who received mechanical ventilation for more than 12 hours.<h4>Interventions</h4>None.<h4>Measurements ... Read more >>

Crit Care Med (Critical care medicine)
[2021, 49(7):1095-1106]

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One-axis Two-wing Guest-Host Strategy for Constructing Ultralong-lifetime Near-infrared Organic Phosphorescence Materials for Bioimaging

Fuming Xiao, Heqi Gao, Yunxiang Lei, Wenbo Dai, Miao-Chang Liu, Xiaoyan Zheng, Zhengxu Cai, Xiaobo Huang, Hua-yue wu, Dan Ding,

Organic near-infrared room temperature phosphorescence (RTP) materials have unparalleled advantages in bioimaging due to their excellent penetrability. However, limited by the energy gap law, organic matters with long wavelengths (> 700 nm) and long lifetimes (> 100 ms) have not been reported so far. In this work, we have obtained organic RTP ... Read more >>

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Early Detection of Legionella pneumophila and Aspergillus by mNGS in a Critically Ill Patient With Legionella Pneumonia After Extracorporeal Membrane Oxygenation Treatment: Case Report and Literature Review.

Ruiming Yue, Xiaoxiao Wu, Tianlong Li, Li Chang, Xiaobo Huang, Lingai Pan,

<i>Legionella pneumophila</i> can cause pneumonia, leading to severe acute respiratory distress syndrome (ARDS). Because of its harsh growth requirements, limited detection methods, and non-specific clinical manifestations, diagnosing <i>Legionella</i> pneumonia remains still challenging. Metagenomic next-generation sequencing (mNGS) technology has increased the rate of detection of <i>Legionella</i>. This study describes a patient ... Read more >>

Front Med (Lausanne) (Frontiers in medicine)
[2021, 8:686512]

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Impact of Pneumocystis Pneumonia on Non-HIV Immunocompromised Patient Outcomes

Ruiming Yue, Shengkun Peng, Yifu Hou, Fuxun Yang, Xiaoqin Zhang, Hongli He, Min cao, Xiaoxiu Luo, Tianlong Li, Xiaobo Huang, Lingai Pan,

<h4>Backgrounds: </h4> Pneumocystis pneumonia (PCP) remains an important cause of morbidity and mortality in non-HIV immunocompromised patients especially solid organ transplant(SOT)recipients. There is a lack of data on the effects of PCP on the outcomes of them. <h4>Method: </h4> We retrospectively analyzed the clinical data of 34 non-HIV immunocompromised patients ... Read more >>

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An electrographic AV optimization for the maximum integrative atrioventricular and ventricular resynchronization in CRT.

Jie Li, Yuegang Wang, Jingting Mai, Shilan Chen, Menghui Liu, Chen Su, Xumiao Chen, Huiling Huang, Yuedong Ma, Chong Feng, Jingzhou Jiang, Jun Liu, Jiangui He, Anli Tang, Yugang Dong, Xiaobo Huang, Yangxin Chen, Lichun Wang,

<h4>Background</h4>Atrioventricular (AV) delay could affect AV and ventricular synchrony in cardiac resynchronization therapy (CRT). Strategies to optimize AV delay according to optimal AV synchrony (AV<sub>opt-AV</sub>) or ventricular synchrony (AV<sub>opt-V</sub>) would potentially be discordant. This study aimed to explore a new AV delay optimization algorithm guided by electrograms to obtain the ... Read more >>

BMC Cardiovasc Disord (BMC cardiovascular disorders)
[2021, 21(1):288]

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Quantifying Radial Growth Response of Pinus Yunnanensis to Climate Change and Drought Event at Different Altitudes and Ages in the Jinsha River Basin

Jianrong Su, Jiayan Shen, Shuaifeng Li, Xiaobo Huang, Wande Liu, Xuedong Lang,

<h4>Background: </h4> The relative influence of climate change and drought events on tree growth at different altitude and tree ages remains insufficiently understood in the Jinsha River Basin, southwest China, limiting prediction of forest adaptability to high-frequency droughts and climate change. We conducted a dendroecological study to explore and quantify ... Read more >>

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Pregnancy Induces an Immunological Memory Characterized by Maternal Immune Alterations Through Specific Genes Methylation.

Xiaobo Huang, Liling Wang, Sijia Zhao, Hong Liu, Si Chen, Li Wu, Liping Liu, Jiahui Ding, Hengwen Yang, Anthony Maxwell, Zhinan Yin, Gil Mor, Aihua Liao,

During pregnancy, the maternal immune system undergoes major adaptive modifications that are necessary for the acceptance and protection of the fetus. It has been postulated that these modifications are temporary and limited to the time of pregnancy. Growing evidence suggests that pregnancy has a long-term impact on maternal health, especially ... Read more >>

Front Immunol (Frontiers in immunology)
[2021, 12:686676]

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Crossing vessels with suspension versus transposition in laparoscopic pyeloplasty of patients with ureteropelvic junction obstruction: a retrospective study.

Jun Liu, Jingjun Zhang, Weinan Chen, Liulin Xiong, Xiaobo Huang, Xiongjun Ye,

<h4>Purpose</h4>To compare the effects of two different methods of laparoscopic pyeloplasty for the treatment of crossing vessels.<h4>Methods</h4>From January 2016 to August 2019, 33 patients with ureteropelvic junction obstruction (UPJO) underwent laparoscopic pyeloplasty at our center, including 21 men and 12 women, ranging from 14 to 66 years of age. There were ... Read more >>

BMC Urol (BMC urology)
[2021, 21(1):77]

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Hybrid Ni3S2-MoS2 nanowire arrays as a pH-universal catalyst for accelerating the hydrogen evolution reaction.

Xundi Gu, Shuangjie Zheng, Xiaobo Huang, Hefeng Yuan, Jinping Li, Manab Kundu, Xiaoguang Wang,

Hybrid Ni3S2-MoS2 NWAs/NF, hybrid Ni3S2-MoS2 nanowire arrays in situ grown on Ni foam via a two-step hydrothermal method, can achieve cathodic current densities of 10 mA cm-2 and 100 mA cm-2 at overpotentials of 99 mV and 260 mV in 1.0 M KOH and 111 mV and 194 mV in ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2020, 56(16):2471-2474]

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Clinical features of imported cases of coronavirus disease 2019 in Tibetan patients in the Plateau area

Yu lei, xiaobo huang, silang bamu, yunping lan, jianli lu, fan zeng,

<h4>Background: </h4> Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, has rapidly spread throughout China, but the clinical characteristics of Tibetan patients living in the Qinghai-Tibetan plateau are unknown. We aimed to investigate the epidemiological, clinical, laboratory and radiological characteristics of these patients. <h4>Methods:</h4> We included 67 Tibetan patients with confirmed ... Read more >>

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Risk factors and prediction model of urosepsis in patients with diabetes after percutaneous nephrolithotomy.

Jun Liu, Qingya Yang, Jiayi Lan, Yang Hong, Xiaobo Huang, Bo Yang,

<h4>Objective</h4>To analyze the risk factors of patients with diabetes mellitus (DM) and urosepsis after percutaneous nephrolithotomy (PCNL) for upper urinary tract stones and to develop a nomogram to predict postoperative urosepsis according to the risk factors.<h4>Methods</h4>The data of patients with type 2 diabetes who underwent one-stage PCNL due to upper ... Read more >>

BMC Urol (BMC urology)
[2021, 21(1):74]

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Efficacy and safety of ultrasound-guided percutaneous nephrolithotomy for kidney calculi patients with ankylosing spondylitis: a retrospective single center analysis.

Mingrui Xia, Yang Hong, Lizhe An, Liulin Xiong, Xiaobo Huang, Qingquan Xu,

<h4>Background</h4>To investigate the efficacy and safety of ultrasound-guided percutaneous nephrolithotomy (PCNL) in kidney calculi patients with ankylosing spondylitis (AS).<h4>Methods</h4>The data of 22 renal stone patients (25 kidney units) with AS who underwent PCNL in our institute from January 2008 to December 2019 were analyzed retrospectively. General information of these patients, ... Read more >>

Ann Palliat Med (Annals of palliative medicine)
[2021, 10(5):5252-5259]

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Atrial myxoma with renal colic

Yang Guo, Min Cao, Xiaobo Huang, Lingai Pan,

<h4>Background: </h4> cardiac myxoma is a common benign tumor of the heart. It can have any presentation such as mitral stenosis, embolization. The best treatment is surgical resection. Case presentation A 30-year-old man presented with 2-days of right renal colic and chest tightness, dyspnea. He was diagnosed as renal infarction ... Read more >>

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Antihypertrophic Memory After Regression of Exercise-Induced Physiological Myocardial Hypertrophy Is Mediated by the Long Noncoding RNA Mhrt779.

Hairuo Lin, Yingqi Zhu, Cankun Zheng, Donghong Hu, Siyuan Ma, Lin Chen, Qiancheng Wang, Zhenhuan Chen, Jiahe Xie, Yi Yan, Xiaobo Huang, Wangjun Liao, Masafumi Kitakaze, Jianping Bin, Yulin Liao,

<h4>Background</h4>Exercise can induce physiological myocardial hypertrophy (PMH), and former athletes can live 5 to 6 years longer than nonathletic controls, suggesting a benefit after regression of PMH. We previously reported that regression of pathological myocardial hypertrophy has antihypertrophic effects. Accordingly, we hypothesized that antihypertrophic memory exists even after PMH has ... Read more >>

Circulation (Circulation)
[2021, 143(23):2277-2292]

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Core-Shell Poly(l-lactic acid)-Hyaluronic Acid Nanofibers for Cell Culture and Pelvic Ligament Tissue Engineering.

Xiaobo Huang, Huaiming Wang, Yingqi Wei, Zifeng Yang, Rongkang Huang, Weiwen Liang, Xiusen Qin, Wentai Guo, Donglin Ren, Lin Jin, Xianhan Jiang, Hui Wang,

Pelvic organ prolapse (POP) has become one of the most common serious diseases affecting parous women. Weakening of pelvic ligaments plays an essential role in the pathophysiology of POP. Currently, synthetic materials are widely applied for pelvic reconstructive surgery. However, synthetic nondegradable meshes for POP therapy cannot meet the clinical ... Read more >>

J Biomed Nanotechnol (Journal of biomedical nanotechnology)
[2021, 17(3):399-406]

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The impact of metabolic syndrome on the safety and efficacy of flexible ureterorenoscopy.

Jun Liu, Yang Hong, Bo Yang, Xiaobo Huang, Qingquan Xu, Liulin Xiong, Xiaofeng Wang,

<h4>Background</h4>To analyze the impact of metabolic syndrome on the safety and efficacy of flexible ureterorenoscopy (fURS) in managing kidney calculi.<h4>Methods</h4>We retrospectively analyzed the records of 151 patients who received fURS for the renal stones in our center between January 2014 and December 2016. The patients were divided into two groups ... Read more >>

Ann Palliat Med (Annals of palliative medicine)
[2021, 10(3):2776-2780]

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An electrographic AV optimization for the maximum integrative atrioventricular and ventricular resynchronization in CRT

JIE LI, Yuegang Wang, Jingting Mai, Shilan Chen, Menghui Liu, Chen Su, Xumiao Chen, Huiling Huang, Yuedong Ma, Chong Feng, Jingzhou Jiang, Jun Liu, Jiangui He, Anli Tang, Yugang Dong, Xiaobo Huang, Yangxin Chen, Lichun Wang,

<h4>Background: </h4> Atrioventricular (AV) delay could affect AV and ventricular synchrony in cardiac resynchronization therapy (CRT). Strategies to optimize AV delay according to optimal AV synchrony (AV opt-AV ) or ventricular synchrony (AV opt-V ) would potentially be in discordant. This study aimed to explore a new AV delay optimization ... Read more >>

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Red blood cell distribution width may be a new factor that influence the selection of invasive treatment in patients with renal abscess.

Mingrui Xia, Jun Liu, Yang Hong, Lizhe An, Liulin Xiong, Xiaobo Huang, Qingquan Xu,

<h4>Background</h4>Red blood cell distribution width (RDW) is associated with the severe morbidity and mortality of some Gram-negative associated chronic diseases. We designed this retrospective study to identify whether RDW can be used as a factor to provide reference for the treatment of renal abscess.<h4>Methods</h4>All patients with renal abscess in our ... Read more >>

Ann Palliat Med (Annals of palliative medicine)
[2021, 10(4):3916-3923]

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Excitation-Dependent Triplet-Singlet Intensity from Organic Host-Guest Materials: Tunable Color, White-Light Emission, and Room-Temperature Phosphorescence.

Dan Wang, Yufeng Xie, Xinghui Wu, Yunxiang Lei, Yunbing Zhou, Zhengxu Cai, Miaochang Liu, Huayue Wu, Xiaobo Huang, Yuping Dong,

A series of organic host-guest materials with multifunctional luminescence were constructed. Four isoquinoline derivatives were used as the guests, and benzophenone was used as the host. The doped system exhibited excellent dual emission with cyan fluorescence and orange-yellow room-temperature phosphorescence, and the dual emission could be combined into almost pure ... Read more >>

J Phys Chem Lett (The journal of physical chemistry letters)
[2021, 12(7):1814-1821]

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Excessive fibroblast growth factor 23 promotes renal fibrosis in mice with type 2 cardiorenal syndrome.

Huixin Hao, Siyuan Ma, Cankun Zheng, Qiancheng Wang, Hairuo Lin, Zhenhuan Chen, Jiahe Xie, Lin Chen, Kaitong Chen, Yuegang Wang, Xiaobo Huang, Shiping Cao, Wangjun Liao, Jianping Bin, Yulin Liao,

Cardiorenal syndrome (CRS) has a high mortality, but its pathogenesis remains elusive. Fibroblast growth factor 23 (FGF23) is increased in both renal dysfunction and cardiac dysfunction, and FGF receptor 4 (FGFR4) has been identified as a receptor for FGF23. Deficiency of FGF23 causes growth retardation and shortens the lifespan, but ... Read more >>

Aging (Albany NY) (Aging)
[2021, 13(2):2982-3009]

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Confluence of Artificial Intelligence and High Performance Computing for Accelerated, Scalable and Reproducible Gravitational Wave Detection

Eliu Huerta, Asad Khan, Xiaobo Huang, Minyang Tian, Maksim Levental, Ryan Chard, Wei Wei, Maeve Heflin, Daniel Katz, Volodymyr Kindratenko, Dawei Mu, Ben Blaiszik, Ian Foster,

<h4>Finding: </h4> new ways to use artificial intelligence (AI) to accelerate the analysis of gravitational wave data, and ensuring the developed models are easily reusable promises to unlock new opportunities in multi-messenger astrophysics (MMA), and to enable wider use, rigorous validation, and sharing of developed models by the community. In ... Read more >>

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Effects of coconut water on blood sugar and retina of rats with diabetes.

Yanan Dai, Li Peng, Xiaohua Zhang, Qingjing Wu, Jie Yao, Qiu Xing, Yunyan Zheng, Xiaobo Huang, Shaomei Chen, Qing Xie,

<h4>Background</h4>This study aimed to evaluate the effects of coconut water on the general condition (fasting blood sugar and body weight) and retina of diabetic rats.<h4>Methods</h4>Forty-eight Sprague-Dawley male rats were divided into normal controls (NC), diabetes mellitus (DM), diabetes+coconut water (DM+CW), and diabetes+glibenclamide (DM+Gli) groups. After 4 weeks of normal feeding, ... Read more >>

PeerJ (PeerJ)
[2021, 9:e10667]

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Concomitant Treatment of Ureteropelvic Junction Obstruction Complicated by Renal Calculi with Laparoscopic Pyeloplasty and Pyelolithotomy via 19.5F Rigid Nephroscope: A Report of 12 Cases.

Lizhe An, Liulin Xiong, Liang Chen, Xiongjun Ye, Xiaobo Huang,

<h4>Objective</h4>To introduce our experience of concomitant laparoscopic pyeloplasty (LP) and pyelolithotomy via 19.5 F rigid nephroscope to treat ureteropelvic junction obstruction (UPJO) complicated with renal calculi.<h4>Methods</h4>The data of 42 patients with UPJO who underwent LP from June 2016 to August 2019 were retrospectively reviewed. Twelve patients with ipsilateral renal calculi underwent ... Read more >>

J Invest Surg (Journal of investigative surgery : the official journal of the Academy of Surgical Research)
[2020, :1-6]

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IPPC: an interactive platform for prostate cancer multi-omics data integration and analysis.

Xiongjun Ye, Fujun Peng, Jun Liu, Haiyue Zhao, Weinan Chen, Huanrui Wang, Peng Zhang, Xiaobo Huang,

J Mol Cell Biol (Journal of molecular cell biology)
[2021, :]

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