Full Text Journal Articles by
Author Xavier Muracciole

Advertisement

Find full text journal articles






The SIOP-Renal Tumour Study Group consensus statement on flank target volume delineation for highly conformal radiotherapy.

Geert O Janssens, Patrick Melchior, Joeri Mul, Daniel Saunders, Stephanie Bolle, Alison L Cameron, Line Claude, Kristin Gurtner, Kees P van de Ven, Martine van Grotel, Semi Harrabi, Yasmin Lassen-Ramshad, Naomi Lavan, Henriette Magelssen, Xavier Muracciole, Tom Boterberg, Henry Mandeville, Jan Godzinski, Norbert Graf, Marry M van den Heuvel-Eibrink, Christian Rübe,

For decades, radiotherapy with two opposing photon beams has been the standard technique used to cover the flank target volume in paediatric patients with renal tumours. Nowadays, many institutes are implementing advanced radiotherapy techniques that spare healthy tissue. To decrease the radiotherapy dose to healthy structures while preserving oncological efficacy, ... Read more >>

Lancet Child Adolesc Health (The Lancet. Child & adolescent health)
[2020, 4(11):846-852]

Cited: 0 times

View full text PDF listing >>



Stereotactic radiosurgery combined with anti-PD1 for the management of melanoma brain metastases: A retrospective study of safety and efficacy.

Romain Carron, Caroline Gaudy-Marqueste, Florent Amatore, Laetitia Padovani, Nausicaa Malissen, Anne Balossier, Anderson Loundou, Nathalie Bonnet, Xavier Muracciole, Jean-Marie Régis, Jean-Jacques Grob,

BACKGROUND:Brain metastases can be effectively treated with stereotactic radiosurgery (SRS). Immune checkpoint inhibitors are now pivotal in metastatic melanoma care, but some concerns have emerged regarding the safety of their combination with radiation therapy. METHODS:We present a retrospective analysis of a cohort of patients treated by anti-PD1 and SRS as ... Read more >>

Eur. J. Cancer (European journal of cancer (Oxford, England : 1990))
[2020, 135:52-61]

Cited: 0 times

View full text PDF listing >>



Advertisement

Exclusive Hyperfractionated Radiation Therapy and Reduced Boost Volume for Standard-Risk Medulloblastoma: Pooled Analysis of the 2 French Multicentric Studies MSFOP98 and MSFOP 2007 and Correlation With Molecular Subgroups.

Christian Carrie, Virginie Kieffer, Dominique Figarella-Branger, Julien Masliah-Planchon, Stéphanie Bolle, Valérie Bernier, Anne Laprie, Stéphane Supiot, Julie Leseur, Jean-Louis Habrand, Claire Alapetite, Christine Kerr, Christelle Dufour, Line Claude, Sophie Chapet, Aymeri Huchet, Pierre-Yves Bondiau, Alexandre Escande, Gilles Truc, Tan Dat Nguyen, Caroline Pasteuris, Céline Vigneron, Xavier Muracciole, Franck Bourdeaut, Romain Appay, Bernard Dubray, Carole Colin, Céline Ferlay, Sophie Dussart, Sylvie Chabaud, Laetitia Padovani, , ,

PURPOSE:Medulloblastoma has recently been characterized as a heterogeneous disease with 4 distinct molecular subgroups: wingless (WNT), sonic hedgehog (SHH), group 3, and group 4, with a new definition of risk stratification. We report progression-free survival, overall survival, and long-term cognitive effects in children with standard-risk medulloblastoma exclusively treated with hyperfractionated ... Read more >>

Int J Radiat Oncol Biol Phys (International journal of radiation oncology, biology, physics)
[2020, 108(5):1204-1217]

Cited: 0 times

View full text PDF listing >>



The outcomes of a second and third Gamma Knife radiosurgery for recurrent essential glossopharyngeal neuralgia.

Anne Balossier, Constantin Tuleasca, Xavier Muracciole, Anne Donnet, Marc Levivier, Jean Régis,

INTRODUCTION:Gamma Knife radiosurgery (GKR) is a minimally invasive surgical option for drug-resistant essential glossopharyngeal neuralgia (GPN). The authors reviewed pain outcomes and complications in GPN patients who underwent a second or a third GKR for recurrent or persistent pain. METHODS:A retrospective review of all patients treated in a single center ... Read more >>

Acta Neurochir (Wien) (Acta neurochirurgica)
[2020, 162(2):271-277]

Cited: 0 times

View full text PDF listing >>



Effect of Adding Docetaxel to Androgen-Deprivation Therapy in Patients With High-Risk Prostate Cancer With Rising Prostate-Specific Antigen Levels After Primary Local Therapy: A Randomized Clinical Trial.

Stéphane Oudard, Igor Latorzeff, Armelle Caty, Laurent Miglianico, Emmanuel Sevin, Anne Claire Hardy-Bessard, Remy Delva, Frédéric Rolland, Loic Mouret, Franck Priou, Philippe Beuzeboc, Gwenaelle Gravis, Claude Linassier, Philippe Gomez, Eric Voog, Xavier Muracciole, Christine Abraham, Eugeniu Banu, Jean-Marc Ferrero, Alain Ravaud, Ivan Krakowski, Jean-Léon Lagrange, Gaël Deplanque, David Zylberait, Laurence Bozec, Nadine Houede, Stéphane Culine, Reza Elaidi,

Importance:Androgen-deprivation therapy (ADT) plus docetaxel is the standard of care in hormone-naive metastatic prostate cancer but is of uncertain benefit in a nonmetastatic, high-risk prostate cancer setting. Objective:To assess the benefit of ADT plus docetaxel in patients presenting with rising prostate-specific antigen (PSA) levels after primary local therapy and high-risk ... Read more >>

JAMA Oncol (JAMA oncology)
[2019, 5(5):623-632]

Cited: 2 times

View full text PDF listing >>



Re-irradiation of locally recurrent pediatric intracranial ependymoma: Experience of the French society of children's cancer.

Elise Régnier, Anne Laprie, Anne Ducassou, Stéphanie Bolle, Stéphane Supiot, Xavier Muracciole, Line Claude, Sophie Chapet, Bernard Coche-Dequéant, Céline Vigneron, Julie Leseur, Pierre Y Bondiau, Jean L Habrand, Valérie Bernier,

PURPOSE:This study aimed to evaluate retrospectively the clinical results of re-irradiation for children with a locally recurrent brain ependymoma. METHODS:33 full-dose re-irradiations were delivered to 31 children with a recurrent brain ependymoma after a standard treatment. Each child was followed up with clinical and MRI examinations. We evaluated overall survival, ... Read more >>

Radiother Oncol (Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology)
[2019, 132:1-7]

Cited: 2 times

View full text PDF listing >>



Negative Survival Impact of High Radiation Doses to Neural Stem Cells Niches in an IDH-Wild-Type Glioblastoma Population.

Xavier Muracciole, Wassim El-Amine, Emmeline Tabouret, Mohamed Boucekine, Anne Barlier, Gregorio Petrirena, Tovo Harivony, Laetitia Solignac, Olivier L Chinot, Nicolas Macagno, Dominique Figarella-Branger, Laetitia Padovani,

Aims: Assess the impact of radiation doses to neural stem cell (NSC) niches in patients with IDH-wild-type glioblastoma. Materials and Methods: Fifty patients were included in the study. NSC niches [SubVentricular Zone (SVZ) and Sub Granular Zone (SGZ)] were contoured by fusing CT scans and pre-therapy MRI, Tumor location defined ... Read more >>

Front Oncol (Frontiers in oncology)
[2018, 8:426]

Cited: 0 times

View full text PDF listing >>



Isolated ipsilateral local recurrence of breast cancer: predictive factors and prognostic impact.

Gilles Houvenaeghel, Alexandre de Nonneville, Monique Cohen, Jean-Marc Classe, Fabien Reyal, Chafika Mazouni, Nicolas Chopin, Alejandra Martinez, Emile Daraï, Charles Coutant, Pierre-Emmanuel Colombo, Pierre Gimbergues, Marie-Pierre Chauvet, Anne-Sophie Azuar, Roman Rouzier, Christine Tunon de Lara, Xavier Muracciole, Aubert Agostini, Anthony Gonçalves, Eric Lambaudie,

BACKGROUND:Tumour features associated with isolated invasive breast cancer (BC) ipsilateral local recurrence (ILR) after breast conservative treatment (BCT) and consequences on overall survival (OS) are still debated. Our objective was to investigate these points. METHODS:Patients were retrospectively identified from a cohort of patients who underwent BCT for invasive BC in ... Read more >>

Breast Cancer Res Treat (Breast cancer research and treatment)
[2019, 173(1):111-122]

Cited: 0 times

View full text PDF listing >>



Immunologically effective dose: a practical model for immuno-radiotherapy.

Raphaël Serre, Fabrice Barlesi, Xavier Muracciole, Dominique Barbolosi,

Concomitant radiotherapy with immune checkpoint blockade could be synergistic. Out-of-field effects could improve survival by slowing or blocking metastatic spreading. However, not much is known about the optimal size per fraction and inter-fraction time in that new context.The new concept of Immunologically Effective Dose (IED) is proposed: it models an ... Read more >>

Oncotarget (Oncotarget)
[2018, 9(61):31812-31819]

Cited: 4 times

View full text PDF listing >>



Daily Versus Weekly Prostate Cancer Image Guided Radiation Therapy: Phase 3 Multicenter Randomized Trial.

Renaud de Crevoisier, Mohamed Amine Bayar, Pascal Pommier, Xavier Muracciole, Françoise Pêne, Philippe Dudouet, Igor Latorzeff, Véronique Beckendorf, Jean-Marc Bachaud, Agnès Laplanche, Stéphane Supiot, Bruno Chauvet, Tan-Dat Nguyen, Alberto Bossi, Gilles Créhange, Jean Léon Lagrange,

PURPOSE:The optimal frequency of prostate cancer image guided radiation therapy (IGRT) has not yet been clearly identified. This study sought to compare the safety and efficacy of daily versus weekly IGRT. MATERIALS AND METHODS:This phase 3 randomized trial recruited patients with N0 localized prostate cancer. The total IGRT doses in ... Read more >>

Int. J. Radiat. Oncol. Biol. Phys. (International journal of radiation oncology, biology, physics)
[2018, 102(5):1420-1429]

Cited: 8 times

View full text PDF listing >>



Pediatric Localized Intracranial Ependymomas: A Multicenter Analysis of the Société Française de lutte contre les Cancers de l'Enfant (SFCE) from 2000 to 2013.

Anne Ducassou, Laetitia Padovani, Leonor Chaltiel, Stéphanie Bolle, Jean-Louis Habrand, Line Claude, Christian Carrie, Xavier Muracciole, Bernard Coche-Dequeant, Claire Alapetite, Stéphane Supiot, Charlotte Demoor-Goldschmidt, Valerie Bernier-Chastagner, Aymeri Huchet, Julie Leseur, Elisabeth Le Prise, Christine Kerr, Gilles Truc, Tan Dat Nguyen, Anne-Isabelle Bertozzi, Didier Frappaz, Sergio Boetto, Annick Sevely, Fatima Tensaouti, Anne Laprie, ,

PURPOSE:The objective of this study was to analyze survival and prognostic factors for children, adolescents, and young adults treated with postoperative radiation therapy (RT) for intracranial ependymoma. METHODS AND MATERIALS:Between 2000 and 2013, 202 patients aged ≤25 years were treated in the 13 main French pediatric RT reference centers. Their ... Read more >>

Int. J. Radiat. Oncol. Biol. Phys. (International journal of radiation oncology, biology, physics)
[2018, 102(1):166-173]

Cited: 4 times

View full text PDF listing >>



Coxiella burnetii Lipopolysaccharide: What Do We Know?

Prasad Abnave, Xavier Muracciole, Eric Ghigo,

A small gram-negative bacterium, Coxiella burnetii (C. burnetii), is responsible for a zoonosis called Q fever. C. burnetii is an intracellular bacterium that can survive inside microbicidal cells like monocytes and macrophages by hijacking several functions of the immune system. Among several virulence factors, the lipopolysaccharide (LPS) of C. burnetii ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2017, 18(12):]

Cited: 1 time

View full text PDF listing >>



Hippocampal Sparing During Craniospinal Irradiation: What Did We Learn About the Incidence of Perihippocampus Metastases?

Laetitia Padovani, Frédérique Chapon, Nicolas André, Mohamed Boucekine, Anne Geoffray, Franck Bourdeau, Julien Masliah-Planchon, Line Claude, Aymeri Huchet, Anne Laprie, Stephane Supiot, Bernard Coche-Dequéant, Christine Kerr, Claire Alapetite, Julie Leseur, Tandat Nguyen, Sophie Chapet, Valerie Bernier, Pierre-Yves Bondiau, Georges Noel, Jean Louis Habrand, Stephanie Bolle, François Doz, Christelle Dufour, Xavier Muracciole, Christian Carrie,

PURPOSE:To identify the incidence of patients with perihippocampal metastases to assess the risk of brain relapse when sparing the hippocampal area. Medulloblastoma (MB) represents 20% of pediatric brain tumors. For high-risk MB patients, the 3- to 5-year event-free survival rate has recently improved from 50% to >76%. Many survivors, however, ... Read more >>

Int J Radiat Oncol Biol Phys (International journal of radiation oncology, biology, physics)
[2018, 100(4):980-986]

Cited: 0 times

View full text PDF listing >>



Patterns of failure after radiotherapy for pediatric patients with intracranial ependymoma.

Fatima Tensaouti, Anne Ducassou, Léonor Chaltiel, Stéphanie Bolle, Xavier Muracciole, Bernard Coche-Dequeant, Claire Alapetite, Valérie Bernier, Line Claude, Stéphane Supiot, Aymeri Huchet, Christine Kerr, Elisabeth le Prisé, Anne Laprie, ,

To investigate the patterns of failure after radiotherapy for pediatric intracranial ependymoma and their correlation with dose parameters.Between 2000 and 2013, 206 patients were treated in France. MRI scans at relapse were registered to the original planning CTs for topographic analysis of failure patterns. To compare relapse patients (RP) with ... Read more >>

Radiother Oncol (Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology)
[2017, 122(3):362-367]

Cited: 7 times

View full text PDF listing >>



Benefit of adjuvant chemotherapy with or without trastuzumab in pT1ab node-negative human epidermal growth factor receptor 2-positive breast carcinomas: results of a national multi-institutional study.

Alexandre de Nonneville, Anthony Gonçalves, Christophe Zemmour, Jean M Classe, Monique Cohen, Eric Lambaudie, Fabien Reyal, Christophe Scherer, Xavier Muracciole, Pierre E Colombo, Sylvia Giard, Roman Rouzier, Richard Villet, Nicolas Chopin, Emile Darai, Jean R Garbay, Pierre Gimbergues, Laura Sabiani, Charles Coutant, Renaud Sabatier, François Bertucci, Jean M Boher, Gilles Houvenaeghel,

Benefit of adjuvant trastuzumab-based chemotherapy for node-positive and/or >1 cm human epidermal growth factor receptor 2-positive (HER2+) breast carcinomas has been clearly demonstrated in randomized clinical trials. Yet, evidence that adjuvant chemotherapy with or without trastuzumab is effective in pT1abN0 HER2+ tumors is still limited. The primary objective of this study ... Read more >>

Breast Cancer Res Treat (Breast cancer research and treatment)
[2017, 162(2):307-316]

Cited: 2 times

View full text PDF listing >>



Macrophages in Invertebrates: From Insects and Crustaceans to Marine Bivalves.

Prasad Abnave, Xavier Muracciole, Eric Ghigo,

Macrophages are critical components of the antimicrobial response. The recent explosion of knowledge on the evolutionary, genetic, and biochemical aspects of the interaction between macrophages and microbes has renewed scientific interest in macrophages. The conservation of immune components or mechanisms between organisms during the evolutionary process allows us to elucidate ... Read more >>

Results Probl Cell Differ (Results and problems in cell differentiation)
[2017, 62:147-158]

Cited: 2 times

View full text PDF listing >>



Mathematical Modeling of Cancer Immunotherapy and Its Synergy with Radiotherapy.

Raphael Serre, Sebastien Benzekry, Laetitia Padovani, Christophe Meille, Nicolas André, Joseph Ciccolini, Fabrice Barlesi, Xavier Muracciole, Dominique Barbolosi,

Combining radiotherapy with immune checkpoint blockade may offer considerable therapeutic impact if the immunosuppressive nature of the tumor microenvironment (TME) can be relieved. In this study, we used mathematical models, which can illustrate the potential synergism between immune checkpoint inhibitors and radiotherapy. A discrete-time pharmacodynamic model of the combination of ... Read more >>

Cancer Res (Cancer research)
[2016, 76(17):4931-4940]

Cited: 36 times

View full text PDF listing >>



Prognostic and predictive values of diffusion and perfusion MRI in paediatric intracranial ependymomas in a large national study.

Fatima Tensaouti, Anne Ducassou, Léonor Chaltiel, Annick Sevely, Stéphanie Bolle, Xavier Muracciole, Bernard Coche-Dequant, Claire Alapetite, Stéphane Supiot, Aymeri Huchet, Valérie Bernier, Line Claude, Anne-Isabelle Bertozzi-Salamon, Samuel Liceaga, Jean Albert Lotterie, Patrice Péran, Pierre Payoux, Anne Laprie, ,

To assess the relative cerebral blood volume (rCBV) and apparent diffusion coefficient (ADC) derived, respectively, from perfusion and diffusion pre-operative MRI of intracranial ependymomas and their predictive and prognostic values.Pre-operative MRI and clinical data for intracranial ependymomas diagnosed between January 2000 and December 2013 were retrospectively retrieved from a web-based ... Read more >>

Br J Radiol (The British journal of radiology)
[2016, 89(1066):20160537]

Cited: 4 times

View full text PDF listing >>



MB-47RISK OF HIPPOCAMPAL REGION METASTASIS IN HIGH RISK MEDULLOBLASTOMA: SUFFICIENT RATIONAL FOR HIPPOCAMPAL SPARING DURING CRANIOSPINAL IRRADIATION?

Laetitia Padovani, Frederique Chapon, Anne Geoffray, Line Claude, Aymeri Huchet, Anne Laprie, Bernard Coche Dequeant, Chrisitne Kerr, Claire Alapetite, Julie Leseur, Sophie Chapet, Valerie Bernier, Pierre Yves Bondiau, Georges Noel, Nicolas Andre, François Doz, Christian Carrie, Christelle Dufour, Xavier Muracciole,

Neuro Oncol (Neuro-oncology)
[2016, 18(Suppl 3):iii107-iii107]

Cited: 0 times

View full text PDF listing >>



An alternative parameter for early forecasting clinical response in NSCLC patients during radiotherapy: proof of concept study.

Laetitia Padovani, Aurelie Baret, Joseph Ciccolini, David Taieb, Farman Bardia, Laetitia Teissonnier, Xavier Muracciole, Fabrice Barlesi, Dominique Barbolosi,

Positron emission tomography with (18)F fludeoxyglucose integrated with CT ((18)F-FDG PET/CT) is a recommended imaging procedure in the evaluation of non-small-cell lung cancers (NSCLCs). Radiochemotherapy (RCT) is a mainstay for treatment of locally advanced NSCLC, for which overall survival still remains poor. Early evaluation of treatment response may help in ... Read more >>

Br J Radiol (The British journal of radiology)
[2016, 89(1062):20160061]

Cited: 2 times

View full text PDF listing >>



Mortality in Children with Optic Pathway Glioma Treated with Up-Front BB-SFOP Chemotherapy.

Josué Rakotonjanahary, Emilie De Carli, Matthieu Delion, Chantal Kalifa, Jacques Grill, François Doz, Pierre Leblond, Anne-Isabelle Bertozzi, Xavier Rialland, ,

BACKGROUND:In terms of overall survival (OS), limited data are available for the very long-term outcomes of children treated for optic pathway glioma (OPG) with up-front chemotherapy. Therefore, we undertook this study with the aim of clarifying long-term OS and causes of death in these patients. METHODS:We initiated and analyzed a ... Read more >>

PLoS One (PloS one)
[2015, 10(6):e0127676]

Cited: 9 times

View full text PDF listing >>



Multicentre randomised phase II trial of gemcitabine+platinum, with or without trastuzumab, in advanced or metastatic urothelial carcinoma overexpressing Her2.

Stéphane Oudard, Stéphane Culine, Yann Vano, François Goldwasser, Christine Théodore, Thierry Nguyen, Eric Voog, Eugeniu Banu, Annick Vieillefond, Franck Priou, Gaël Deplanque, Gwenaëlle Gravis, Alain Ravaud, Jean Michel Vannetzel, Jean-Pascal Machiels, Xavier Muracciole, Marie-France Pichon, Jacques-Olivier Bay, Reza Elaidi, Corine Teghom, François Radvanyi, Philippe Beuzeboc,

AIM: To investigate the efficacy and safety of gemcitabine and platinum salt, with or without trastuzumab, in patients with locally advanced or metastatic urothelial carcinoma overexpressing Her2. METHODS: The main eligibility criterion was Her2 overexpression on immunohistochemistry (IHC 2+ or 3+) of primary tumour tissue confirmed by fluorescence in situ ... Read more >>

Eur. J. Cancer (European journal of cancer (Oxford, England : 1990))
[2015, 51(1):45-54]

Cited: 35 times

View full text PDF listing >>



Cost of prostate image-guided radiation therapy: results of a randomized trial.

Lionel Perrier, Magali Morelle, Pascal Pommier, Jean-Léon Lagrange, Agnès Laplanche, Philippe Dudouet, Stéphane Supiot, Bruno Chauvet, Tan-Dat Nguyen, Gilles Crehange, Véronique Beckendorf, Françoise Pene, Xavier Muracciole, Jean-Marc Bachaud, Elisabeth Le Prisé, Renaud de Crevoisier,

PURPOSE: This cost analysis aimed to quantify the cost of IGRT in relation to IGRT frequency and modality with Cone Beam Computed Tomography (CBCT) or orthogonal electronic portal imaging with fiducial markers (EPI-FM). MATERIAL AND METHODS: Patients undergoing IGRT for localized prostate cancer were randomized into two prostate control frequencies ... Read more >>

Radiother Oncol (Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology)
[2013, 106(1):50-58]

Cited: 16 times

View full text PDF listing >>



Neurocognitive function after radiotherapy for paediatric brain tumours.

Laetitia Padovani, Nicolas André, Louis S Constine, Xavier Muracciole,

The brain is highly vulnerable to neurotoxic agents during the prime learning period of a child's life. Paediatric patients with brain tumours who are treated with cranial radiation therapy (CRT) often go on to develop neurocognitive deficits, which are reflected in poor academic achievement and impaired memory, attention and processing ... Read more >>

Nat Rev Neurol (Nature reviews. Neurology)
[2012, 8(10):578-588]

Cited: 46 times

View full text PDF listing >>



γ knife radiosurgery of brain metastasis from breast cancer.

Laetitia Padovani, Xavier Muracciole, Jean Régis,

The incidence of brain metastasis in patients with metastatic breast cancer ranges from 14 to 16%.Age, number of metastatic sites, short disease-free survival and molecular subtypes are associated with the occurrence of brain metastasis. Patients classified in the triple-negative group more frequently presented brain metastasis as the first site (26%) ... Read more >>

Prog Neurol Surg (Progress in neurological surgery)
[2012, 25:156-162]

Cited: 6 times

View full text PDF listing >>



Advertisement

Disclaimer
1.1387 s