Full Text Journal Articles by
Author Wiparat Manuyakorn

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Diagnosis of Hyper IgM syndrome in a Previously Healthy Adolescent Boy Presented with Cutaneous and Cerebral Cryptococcosis.

Athipat Athipongarporn, Chupong Ittiwut, Wiparat Manuyakorn, Surapat Assawawiroonhakarn, Noppadol Larbcharoensub, Vorasuk Shotelersuk,

X-linked hyper IgM (X-HIGM) syndrome is a combined immunodeficiency disease caused by mutations in the CD40LG gene, leading to a defect in immunoglobulin (Ig) class switching recombination and effector T-cell responses. X-HIGM patients usually present in early life with pyogenic bacterial and opportunistic infections. Herein, we report a previously healthy ... Read more >>

Pediatr Infect Dis J (The Pediatric infectious disease journal)
[2021, 40(1):e18-e20]

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Favorable Response to Interferon-α in Infantile-onset Idiopathic Hypereosinophilic Syndrome Complicated by Status Epilepticus During Treatment.

Watcharoot Kanchongkittiphon, Kornvipa Kittinon, Anyarat Wanitchakorn, Suwat Benjaponpitak, Wiparat Manuyakorn,

J Pediatr Hematol Oncol (Journal of pediatric hematology/oncology)
[2021, :]

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Zinc and vitamin C deficiencies associate with poor pulmonary function in children with persistent asthma.

Siriporn Siripornpanich, Nalinee Chongviriyaphan, Wiparat Manuyakorn, Ponpan Matangkasombut,

<h4>Background</h4>One of the pathophysiologic mechanisms involved in asthma is the increase in oxidative stress. Zinc (Zn), vitamin C (VC), and vitamin E (VE) have antioxidant functions. However, the status of oxidative stress, Zn, VC, and VE in Thai asthmatic children have not been reported.<h4>Objective</h4>We aimed to evaluate the status of ... Read more >>

Asian Pac J Allergy Immunol (Asian Pacific journal of allergy and immunology)
[2020, :]

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Proteomic analysis reveals plasma haptoglobin, interferon-γ, and interleukin-1β as potential biomarkers of pediatric refractory epilepsy.

Vitchayaporn Emarach Saengow, Wararat Chiangjong, Chaiyos Khongkhatithum, Channarong Changtong, Daranee Chokchaichamnankit, Churat Weeraphan, Patcharin Kaewboonruang, Lunliya Thampratankul, Wiparat Manuyakorn, Suradej Hongeng, Chantragan Srisomsap, Jisnuson Svasti, Somchai Chutipongtanate, Anannit Visudtibhan,

<h4>Background</h4>Children with refractory epilepsy (RE) are associated with increased mortality rate, nonfatal injuries, disability, and diminished quality of life. Biomarkers for the early prediction of RE is still an unmet need.<h4>Methods</h4>Eighteen children with RE and six age-matched unrelated controls were included in this study. Plasma samples were prefractionated by the ... Read more >>

Brain Dev (Brain & development)
[2020, :]

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Regulatory T cell and cytokine changes in children undergoing 3 days rush venom immunotherapy.

Tipyapa Rattanamanee, Putthapoom Lumjiaktase, Nanthisa Kemawichanura, Potjanee Kiewgnam, Wanlapa Jotikasthira, Wiparat Manuyakorn,

<h4>Background</h4>Rush venom immunotherapy (VIT) is the recommended treatment for patients with Hymenoptera anaphylaxis. Specific data regarding regulatory T cell and cytokine changes in children receiving rush VIT are sparse.<h4>Objective</h4>To study the changing of CD4+CD25+FOXP3+ regulatory T cells (Treg) and serum cytokines in children undergoing 3 days rush VIT.<h4>Methods</h4>Children younger than ... Read more >>

Asian Pac J Allergy Immunol (Asian Pacific journal of allergy and immunology)
[2020, :]

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Skin Prick Test Versus Phadiatop as a Tool for Diagnosis of Allergic Rhinitis in Children.

Sasiwimon Traiyan, Wiparat Manuyakorn, Watcharoot Kanchongkittiphon, Cherapat Sasisakulporn, Wanlapa Jotikasthira, Potjanee Kiewngam, Wasu Kamchaisatian, Suwat Benjaponpitak,

<h4>Background</h4>Skin prick test (SPT) or Phadiatop, a multi-allergen IgE screening test, was used as a tool for detecting aeroallergen sensitization.<h4>Objective</h4>To compare SPT and Phadiatop as a tool for diagnosis allergic rhinitis (AR) using the nasal provocation test (NPT) as a comparative standard.<h4>Methods</h4>Children aged 5-18 years with rhinitis symptoms more than ... Read more >>

Am J Rhinol Allergy (American journal of rhinology & allergy)
[2021, 35(1):98-106]

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Association of HLA genotypes with phenytoin induced severe cutaneous adverse drug reactions in Thai children.

Wiparat Manuyakorn, Plernpit Likkasittipan, Sukanya Wattanapokayakit, Supharat Suvichapanich, Wimala Inunchot, Nuanjun Wichukchinda, Chaiyos Khongkhatithuml, Lunliya Thampratankul, Wasu Kamchaisatian, Suwat Benjaponpitak, Surakameth Mahasirimongkol,

PURPOSE:Phenytoin (PHT) is a common causative drug for severe cutaneous adverse drug reactions (SCARs) in children. SCARs, including drug reaction with eosinophilia and systemic symptoms (DRESS), Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), are associated with a variation in HLA genotypes. Blood screening for specific HLA allele before PHT ... Read more >>

Epilepsy Res (Epilepsy research)
[2020, 162:106321]

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Novel salivary gland allergens from tropical mosquito species and IgE reactivity in allergic patients.

Anunya Opasawatchai, Watchareewan Yolwong, Walairat Thuncharoen, Nanthicha Inrueangsri, Sulak Itsaradisaikul, Cherapat Sasisakulporn, Wanlapa Jotikasthira, Oranart Matangkasombut, Onrapak Reamtong, Wiparat Manuyakorn, Wisuwat Songnuan, Ponpan Matangkasombut,

Background:Mosquito allergy is common in tropical countries but remains under-diagnosed. This may be due to the lack of knowledge and diagnostic tools for tropical mosquito allergens. Objective:We aimed to characterize allergens from tropical mosquito species and investigate IgE reactivity in mosquito-allergic patients to the salivary gland proteins from these mosquitoes. ... Read more >>

World Allergy Organ J (The World Allergy Organization journal)
[2020, 13(2):100099]

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Forced oscillation technique as a predictor for loss of control in asthmatic children.

Piyawut Kreetapirom, Potjanee Kiewngam, Wanlapa Jotikasthira, Wasu Kamchaisatian, Suwat Benjaponpitak, Wiparat Manuyakorn,

Background:A reliable objective tool using as a predictor of asthma control status could assist asthma management. Objective:To find the parameters of forced oscillation technique (FOT) as predictors for the future loss of asthma symptom control. Methods:Children with well-controlled asthma symptom, aged 6-12 years, were recruited for a 12-week prospective study. ... Read more >>

Asia Pac Allergy (Asia Pacific allergy)
[2020, 10(1):e3]

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Efficacy of a newly developed cartoon video on dry powder inhaler technique: a multicenter study.

Thitima Sirimontakan, Wiparat Manuyakorn, Harutai Kamalaporn, Pornchai Wattanarungsun, Kuntalee Chonpaisan, Korakot Thongkum, Prapasiri Singvijarn, Sintra Phumethum,

BACKGROUND:One of the factors associated with uncontrolled pediatric asthma is inadequate delivery of inhaled medication to the lungs. Incorrect inhaler technique has been reported. We developed a 2-minute cartoon video instruction aiming to improve dry powder inhaler (DPI) technique. OBJECTIVE:To assess the efficacy of video instruction in improvement of DPI ... Read more >>

Asian Pac J Allergy Immunol (Asian Pacific journal of allergy and immunology)
[2019, :]

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Effect of vitamin D on lung function assessed by forced oscillation technique in asthmatic children with vitamin D deficiency: A randomized double-blind placebo-controlled trial.

Napatsayod Swangtrakul, Wiparat Manuyakorn, Pat Mahachoklertwattana, Potjanee Kiewngam, Cherapat Sasisakulporn, Wanlapa Jotikasthirapa, Wasu Kamchaisatian, Suwat Benjaponpitak,

BACKGROUND:The role of vitamin D and asthma in pulmonary function changes showed conflicting result. OBJECTIVE:To evaluate if vitamin D treatment would improve lung function assessed by forced oscillation technique (FOT) in vitamin D deficient asthmatic children. METHODS:A randomized double-blind placebo-controlled trial was performed in children, aged 3-18 years with well ... Read more >>

Asian Pac J Allergy Immunol (Asian Pacific journal of allergy and immunology)
[2019, :]

Cited: 1 time

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Compound Heterozygous PGM3 Mutations in a Thai Patient with a Specific Antibody Deficiency Requiring Monthly IVIG Infusions.

Chupong Ittiwut, Wiparat Manuyakorn, Siraprapa Tongkobpetch, Suwat Benjaponpitak, Megan R Fisher, Joshua D Milner, Jonathan J Lyons, Kanya Suphapeetiporn, Vorasuk Shotelersuk,

J Clin Immunol (Journal of clinical immunology)
[2020, 40(1):227-231]

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Successful haploidentical hematopoietic stem cell transplantation with post-transplant cyclophosphamide in a child with X-linked chronic granulomatous disease: A first report in Asia.

Chawisa Janjindamai, Wiparat Manuyakorn, Usanarat Anurathapan, Samart Pakakasama, Duangrurdee Wattanasirichaigoon, Wasu Kamchaisatian, Suwat Benjaponpitak, Suradej Hongeng,

<h4>Backgound</h4>HLA-matched hematopoietic stem cell transplantation (HSCT) is the curative treatment for chronic granulomatous disease (CGD).<h4>Objective</h4>To report a case of X-linked CGD with active infection successfully treated by haploidentical HSCT with post-transplant high dose cyclophosphamide (PTCY).<h4>Methods</h4>A 5-year-old Thai boy with CGD was undergone for haploidentical HSCT using PTCY with correction of ... Read more >>

Asian Pac J Allergy Immunol (Asian Pacific journal of allergy and immunology)
[2019, :]

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Association of HLA genotypes with Beta-lactam antibiotic hypersensitivity in children.

Prapasiri Singvijarn, Wiparat Manuyakorn, Surakameth Mahasirimongkol, Sukanya Wattanapokayakit, Wimala Inunchot, Nuanjun Wichukchinda, Supharat Suvichapanich, Wasu Kamchaisatian, Suwat Benjaponpitak,

<h4>Background</h4>Beta-lactam (BL) antibiotics hypersensitivity is common in children. Clinical manifestation of BL hypersensitivity varies from mild to severe cutaneous adverse drug reactions (SCARs).<h4>Objective</h4>To determine the association of HLA genotype and BL hypersensitivity and the prevalence of true drug allergy in patients with history of BL hypersensitivity.<h4>Methods</h4>A case-control study was performed ... Read more >>

Asian Pac J Allergy Immunol (Asian Pacific journal of allergy and immunology)
[2019, :]

Cited: 1 time

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Reference value of Forced Oscillation Technique for healthy preschool children.

Pinyapa Mukdjindapa, Wiparat Manuyakorn, Potjanee Kiewngam, Cherapat Sasisakulporn, Pisut Pongchaikul, Wasu Kamchaisatian, Suwat Benjaponpitak,

<h4>Background</h4>The reference values of Forced Oscillation Technique (FOT) parameters of the inspiratory and expiratory phase for preschool children have not yet been established.<h4>Objective</h4>To evaluate FOT measures in Thai healthy preschool children.<h4>Methods</h4>Preschool children, aged 3-6 years, were screened. Children who were positive for the International Study of Asthma and Allergies in ... Read more >>

Asian Pac J Allergy Immunol (Asian Pacific journal of allergy and immunology)
[2018, :]

Cited: 0 times

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De novo food allergy in pediatric liver transplantation recipients.

Ratchaneewan Sinitkul, Wiparat Manuyakorn, Wasu Kamchaisatian, Soamarat Vilaiyuk, Suwat Benjaponpitak, Chatmanee Lertudompholwanit, Suporn Treepongkaruna,

BACKGROUND:Food allergy (FA) prevalence is increasing in pediatric liver transplantation (LT). However, the clinical course is still limited. OBJECTIVE:This retrospective cohort study aimed to identify the prevalence, risk factors, and the natural history of de novo FA in children post LT. METHODS:Medical records of pediatric LT recipients from Jan 2001 ... Read more >>

Asian Pac J Allergy Immunol (Asian Pacific journal of allergy and immunology)
[2018, 36(3):166-174]

Cited: 1 time

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Cow milk protein allergy and other common food allergies and intolerances.

Wiparat Manuyakorn, Pornthep Tanpowpong,

The prevalence of food allergy and food intolerance is increasing and it is an important public health problem affecting children. Food allergy results from an immunological reaction to certain food(s) and affects numerous organs in the body. Food intolerances are non-immunological reactions including metabolic, toxic, pharmacological and undefined mechanisms. Cow ... Read more >>

Paediatr Int Child Health (Paediatrics and international child health)
[2019, 39(1):32-40]

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Solenopsis geminata (tropical fire ant) anaphylaxis among Thai patients: its allergens and specific IgE-reactivity.

Rutcharin Potiwat, Sasipa Tanyaratsrisakul, Santi Maneewatchararangsri, Wiparat Manuyakorn, Ticha Rerkpattanapipat, Yudthana Samung, Chukiat Sirivichayakul, Wanpen Chaicumpa, Raweerat Sitcharungsi,

<h4>Background</h4>Specific IgE against Solenopsis invicta (imported fire ant) remains the current diagnostic tool for allergy to ants worldwide. However, S. invicta may not be the only cause of ant anaphylaxis in Thai patients.<h4>Objective</h4>To characterize ant species causing anaphylaxis in Thai patients and to test allergenic reactivity to whole body extracts ... Read more >>

Asian Pac J Allergy Immunol (Asian Pacific journal of allergy and immunology)
[2018, 36(2):101-108]

Cited: 3 times

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Needle length for epinephrine prefilled syringes in children and adolescents: Is one inch needle appropriate?

Wiparat Manuyakorn, Buntita Bamrungchaowkasem, Nichanan Ruangwattanapaisarn, Wasu Kamchaisatian, Suwat Benjaponpitak,

<h4>Background</h4>Intramuscular epinephrine is the first line drug in the treatment of anaphylaxis. This study was to identify the appropriateness of 1 inch needle length for epinephrine prefilled syringes in children.<h4>Methods</h4>Children aged 1 month to 18 years were enrolled. Skin to muscle depth (STMD) and skin to bone depth (STBD) were ... Read more >>

Asian Pac J Allergy Immunol (Asian Pacific journal of allergy and immunology)
[2018, 36(2):113-119]

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The effectiveness of newly developed written asthma action plan in improvement of asthma outcome in children.

Kingthong Lakupoch, Wiparat Manuyakorn, Aroonwan Preutthipan, Harutai Kamalaporn,

<h4>Background</h4>Providing asthma education about controller medication use and appropriate management of asthma exacerbation are the keys to improving the disease outcome. Many asthma guidelines recommend that physicians provide written asthma action plan (WAAP) to all of their asthmatic patients. However, the benefit of WAAP is unclear. Thus, we have created ... Read more >>

Asian Pac J Allergy Immunol (Asian Pacific journal of allergy and immunology)
[2018, 36(2):88-92]

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Mosquito allergy in children: Clinical features and limitation of commercially-available diagnostic tests.

Wiparat Manuyakorn, Sulak Itsaradisaikul, Suwat Benjaponpitak, Wasu Kamchaisatian, Cherapat Sasisakulporn, Wanlapa Jotikasthira, Ponpan Matangkasombut,

<h4>Objective</h4>To determine the clinical features of mosquito allergy in children and the ability of commercially available mosquito allergy tests to detect children with mosquito allergy in Thailand.<h4>Methods</h4>Patients with mosquito allergy aged 1 month to 18 years were recruited. Demographic data, history of mosquito allergy (onset of the reaction, reaction type) ... Read more >>

Asian Pac J Allergy Immunol (Asian Pacific journal of allergy and immunology)
[2017, 35(4):186-190]

Cited: 2 times

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Safety and efficacy of ant rush immunotherapy in children.

Wiparat Manuyakorn, Suwat Benjaponpitak, Wasu Kamchaisatian, Cherapat Sasisakulporn, Wanlapa Jotikasthira,

<h4>Background</h4>The Rush Immunotherapy (RIT) protocol is a valid alternative in order to reach the maintenance phase early. However, there are scarce studies in the literature that have evaluated the safety and the efficacy of an ant RIT process in children.<h4>Objective</h4>To evaluate the safety and the efficacy of an ant RIT ... Read more >>

Asian Pac J Allergy Immunol (Asian Pacific journal of allergy and immunology)
[2017, 35(3):156-160]

Cited: 0 times

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Association of indoor air quality and preschool children's respiratory symptoms.

Sirinapa Siwarom, Pongtong Puranitee, Adisak Plitponkarnpim, Wiparat Manuyakorn, Ratchaneewan Sinitkul, Sakda Arj-Ong Vallipakorn,

<h4>Background</h4>This study aimed to assess the association between exposure to indoor air pollution in DCCs (Child Day Care Centers) and the respiratory symptoms of children under 6 years old.<h4>Methods</h4>Air quality data were collected three times regarding to seasonal variation. Pollutants measured in 11 DCCs included PM₁₀, CO, NO₂, SO₂, O₃, ... Read more >>

Asian Pac J Allergy Immunol (Asian Pacific journal of allergy and immunology)
[2017, 35(3):119-126]

Cited: 1 time

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Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Standard Reporting and Evaluation Guidelines: Results of a National Institutes of Health Working Group.

Emanual Maverakis, Elizabeth A Wang, Kanade Shinkai, Surakameth Mahasirimongkol, David J Margolis, Mark Avigan, Wen-Hung Chung, Jennifer Goldman, Lois La Grenade, Munir Pirmohamed, Neil H Shear, Wichittra Tassaeeyakul, Wolfram Hoetzenecker, Jettanong Klaewsongkram, Ticha Rerkpattanapipat, Wiparat Manuyakorn, Sally Usdin Yasuda, Victoria R Sharon, Andrea Sukhov, Robert Micheletti, Jeff Struewing, Lars E French, Michelle Y Cheng,

<h4>Importance</h4>Toxic epidermal necrolysis (TEN) and Stevens-Johnson Syndrome (SJS) are rare, acute, life-threatening dermatologic disorders involving the skin and mucous membranes. Research into these conditions is hampered by a lack of standardization of case reporting and data collection.<h4>Objective</h4>To establish a standardized case report form to facilitate comparisons and maintain data quality ... Read more >>

JAMA Dermatol (JAMA dermatology)
[2017, 153(6):587-592]

Cited: 9 times

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Optimal needle length for epinephrine prefilled syringe in children.

Wiparat Manuyakorn, Buntita Bamrungchaowkasem, Nichanan Ruangwattanapaisarn, Wasu Kamchaisatian, Suwat Benjaponpitak,

Ann Allergy Asthma Immunol (Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology)
[2017, 118(6):740-741.e1]

Cited: 0 times

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