Full Text Journal Articles by
Author William J Powers

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Strokelore: Angiographic Diagnosis of Primary Angiitis of the Central Nervous System.

William J Powers,

J Stroke Cerebrovasc Dis (Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association)
[2021, 30(11):106060]

Cited: 0 times

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ACR Appropriateness Criteria® Syncope.

, Seth J Kligerman, Julie Bykowski, Lynne M Hurwitz Koweek, Bruno Policeni, Brian B Ghoshhajra, Michael D Brown, Andrew M Davis, Elizabeth H Dibble, Thomas V Johnson, Faisal Khosa, Luke N Ledbetter, Steve W Leung, David S Liebeskind, Diana Litmanovich, Christopher D Maroules, Jeffrey S Pannell, William J Powers, Todd C Villines, Lily L Wang, Samuel Wann, Amanda S Corey, Suhny Abbara,

Syncope and presyncope lead to well over one million emergency room visits in the United States each year. Elucidating the cause of syncope or presyncope, which are grouped together given similar etiologies and outcomes, can be exceedingly difficult given the diverse etiologies. This becomes more challenging as some causes, such ... Read more >>

J Am Coll Radiol (Journal of the American College of Radiology : JACR)
[2021, 18(5S):S229-S238]

Cited: 0 times

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Clinical utility of echocardiography in secondary ischemic stroke prevention.

William J Powers,

Echocardiography employs ultrasound to evaluate cardiac function, structure and pathology. The clinical value in secondary ischemic stroke prevention depends on identification of associated conditions for which a change in treatment from antiplatelet agents and risk factor intervention leads to improved outcomes. Such therapeutically relevant findings include primarily intracardiac thrombus, valvular ... Read more >>

Handb Clin Neurol (Handbook of clinical neurology)
[2021, 177:359-375]

Cited: 0 times

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Recurrent Hemispheric Stroke Syndromes in Symptomatic Atherosclerotic Internal Carotid Artery Occlusions: The Carotid Occlusion Surgery Study Randomized Trial.

Fadi Nahab, Michael Liu, Haseeb A Rahman, Srikant Rangaraju, Daniel Barrow, C Michael Cawley, Robert L Grubb, Colin P Derdeyn, Harold P Adams, Tom O Videen, M Bridget Zimmerman, William J Powers,

<h4>Background</h4>There are limited data on outcomes of extracranial-intracranial (EC-IC) bypass in patients with recurrent hemispheric syndromes due to atherosclerotic internal carotid artery occlusion (AICAO).<h4>Objective</h4>To compare clinical outcomes and efficacy of EC-IC bypass surgery in patients with and without recurrent hemispheric syndromes associated with AICAO in the Carotid Occlusion Surgery Study ... Read more >>

Neurosurgery (Neurosurgery)
[2020, 87(1):137-141]

Cited: 1 time

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Acute Ischemic Stroke.

William J Powers,

N Engl J Med (The New England journal of medicine)
[2020, 383(3):252-260]

Cited: 9 times

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Diagnostic accuracy of acute infarcts in multiple cerebral circulations for cardioembolic stroke: Literature review and meta-analysis.

William J Powers, Candice H Kam, Victor S Ritter, Jason P Fine,

<h4>Objective</h4>To determine the diagnostic value of acute infarcts in multiple cerebral circulations (AIMCC) on MRI diffusion-weighted imaging (DWI) for cardioembolism (CE) stroke subtype in adult patients hospitalized with acute ischemic stroke, we conducted a systematic literature review and meta-analysis.<h4>Methods</h4>MEDLINE was searched via PubMed for articles reporting patients hospitalized with acute ... Read more >>

J Stroke Cerebrovasc Dis (Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association)
[2020, 29(7):104849]

Cited: 0 times

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ACR Appropriateness Criteria® Movement Disorders and Neurodegenerative Diseases.

, H Benjamin Harvey, Laura C Watson, Rathan M Subramaniam, Judah Burns, Julie Bykowski, Santanu Chakraborty, Luke N Ledbetter, Ryan K Lee, Jeffrey S Pannell, Jeffrey M Pollock, William J Powers, Joshua M Rosenow, Robert Y Shih, Konstantin Slavin, Pallavi S Utukuri, Amanda S Corey,

Movement disorders and neurodegenerative diseases are a variety of conditions that involve progressive neuronal degeneration, injury, or death. Establishing the correct diagnosis of a movement disorder or neurodegenerative process can be difficult due to the variable features of these conditions, unusual clinical presentations, and overlapping symptoms and characteristics. MRI has ... Read more >>

J Am Coll Radiol (Journal of the American College of Radiology : JACR)
[2020, 17(5S):S175-S187]

Cited: 0 times

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ACR Appropriateness Criteria® Dementia.

, Gul Moonis, Rathan M Subramaniam, Anna Trofimova, Judah Burns, Julie Bykowski, Santanu Chakraborty, Kathryn Holloway, Luke N Ledbetter, Ryan K Lee, Jeffrey S Pannell, Jeffrey M Pollock, William J Powers, Robert P Roca, Joshua M Rosenow, Robert Y Shih, Pallavi S Utukuri, Amanda S Corey,

Degenerative disease of the central nervous system is a growing public health concern. The primary role of neuroimaging in the workup of patients with probable or possible Alzheimer disease has typically been to exclude other significant intracranial abnormalities. In general, the imaging findings in structural studies, such as MRI, are ... Read more >>

J Am Coll Radiol (Journal of the American College of Radiology : JACR)
[2020, 17(5S):S100-S112]

Cited: 3 times

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ACR Appropriateness Criteria® Headache.

, Matthew T Whitehead, Agustin M Cardenas, Amanda S Corey, Bruno Policeni, Judah Burns, Santanu Chakraborty, R Webster Crowley, Pascal Jabbour, Luke N Ledbetter, Ryan K Lee, Jeffrey S Pannell, Jeffrey M Pollock, William J Powers, Gavin Setzen, Robert Y Shih, Rathan M Subramaniam, Pallavi S Utukuri, Julie Bykowski,

Headache is one of the most common human afflictions. In most cases, headaches are benign and idiopathic, and resolve spontaneously or with minor therapeutic measures. Imaging is not required for many types of headaches. However, patients presenting with headaches in the setting of "red flags" such as head trauma, cancer, ... Read more >>

J Am Coll Radiol (Journal of the American College of Radiology : JACR)
[2019, 16(11S):S364-S377]

Cited: 4 times

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Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association.

William J Powers, Alejandro A Rabinstein, Teri Ackerson, Opeolu M Adeoye, Nicholas C Bambakidis, Kyra Becker, José Biller, Michael Brown, Bart M Demaerschalk, Brian Hoh, Edward C Jauch, Chelsea S Kidwell, Thabele M Leslie-Mazwi, Bruce Ovbiagele, Phillip A Scott, Kevin N Sheth, Andrew M Southerland, Deborah V Summers, David L Tirschwell,

Background and Purpose- The purpose of these guidelines is to provide an up-to-date comprehensive set of recommendations in a single document for clinicians caring for adult patients with acute arterial ischemic stroke. The intended audiences are prehospital care providers, physicians, allied health professionals, and hospital administrators. These guidelines supersede the ... Read more >>

Stroke (Stroke)
[2019, 50(12):e344-e418]

Cited: 447 times

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Response by Powers and Rabinstein to Letter Regarding Article, "2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association".

William J Powers, Alejandro A Rabinstein,

Stroke (Stroke)
[2019, 50(9):e277-e278]

Cited: 0 times

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ACR Appropriateness Criteria® Neuroendocrine Imaging.

, Judah Burns, Bruno Policeni, Julie Bykowski, Prachi Dubey, Isabelle M Germano, Vikas Jain, Amy F Juliano, Gul Moonis, Matthew S Parsons, William J Powers, Tanya J Rath, Jason W Schroeder, Rathan M Subramaniam, M Reza Taheri, Matthew T Whitehead, David Zander, Amanda Corey,

Neuroendocrine dysfunction includes suspected hyper- and hypofunction of the pituitary gland. Causative lesions may include primary masses of the pituitary such as pituitary microadenomas and macroadenomas, as well as extrinsic masses, typically centered in the suprasellar cistern. Clinical syndromes related to hormonal dysfunction can be caused by excessive hormonal secretion ... Read more >>

J Am Coll Radiol (Journal of the American College of Radiology : JACR)
[2019, 16(5S):S161-S173]

Cited: 0 times

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ACR Appropriateness Criteria® Ataxia.

, Amy F Juliano, Bruno Policeni, Vikas Agarwal, Judah Burns, Julie Bykowski, H Benjamin Harvey, Jenny K Hoang, Christopher H Hunt, Tabassum A Kennedy, Gul Moonis, Jeffrey S Pannell, Matthew S Parsons, William J Powers, Joshua M Rosenow, Jason W Schroeder, Konstantin Slavin, Matthew T Whitehead, Amanda S Corey,

Ataxia can result from an abnormality in the cerebellum, spinal cord, peripheral nerves, and/or vestibular system. Pathology involving the brain, such as infarct or hydrocephalus, can also present with ataxia as part of the symptom constitution, or result in symptoms that mimic ataxia. Clinical evaluation by history and careful neurological ... Read more >>

J Am Coll Radiol (Journal of the American College of Radiology : JACR)
[2019, 16(5S):S44-S56]

Cited: 2 times

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Additional Factors in Considering Patent Foramen Ovale Closure to Prevent Recurrent Ischemic Stroke.

William J Powers,

JAMA Neurol (JAMA neurology)
[2018, 75(7):895]

Cited: 1 time

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Intravenous Alteplase for Mild Nondisabling Acute Ischemic Stroke: A Bridge Too Far?

William J Powers,

JAMA (JAMA)
[2018, 320(2):141-143]

Cited: 2 times

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ACR Appropriateness Criteria® Orbits Vision and Visual Loss.

, Tabassum A Kennedy, Amanda S Corey, Bruno Policeni, Vikas Agarwal, Judah Burns, H Benjamin Harvey, Jenny Hoang, Christopher H Hunt, Amy F Juliano, William Mack, Gul Moonis, Gregory J A Murad, Jeffrey S Pannell, Matthew S Parsons, William J Powers, Jason W Schroeder, Gavin Setzen, Matthew T Whitehead, Julie Bykowski,

Visual loss can be the result of an abnormality anywhere along the visual pathway including the globe, optic nerve, optic chiasm, optic tract, thalamus, optic radiations or primary visual cortex. Appropriate imaging analysis of visual loss is facilitated by a compartmental approach that establishes a differential diagnosis on the basis ... Read more >>

J Am Coll Radiol (Journal of the American College of Radiology : JACR)
[2018, 15(5S):S116-S131]

Cited: 1 time

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2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association.

William J Powers, Alejandro A Rabinstein, Teri Ackerson, Opeolu M Adeoye, Nicholas C Bambakidis, Kyra Becker, José Biller, Michael Brown, Bart M Demaerschalk, Brian Hoh, Edward C Jauch, Chelsea S Kidwell, Thabele M Leslie-Mazwi, Bruce Ovbiagele, Phillip A Scott, Kevin N Sheth, Andrew M Southerland, Deborah V Summers, David L Tirschwell, ,

BACKGROUND AND PURPOSE:The purpose of these guidelines is to provide an up-to-date comprehensive set of recommendations for clinicians caring for adult patients with acute arterial ischemic stroke in a single document. The intended audiences are prehospital care providers, physicians, allied health professionals, and hospital administrators. These guidelines supersede the 2013 ... Read more >>

Stroke (Stroke)
[2018, 49(3):e46-e110]

Cited: 1134 times

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Dissociation Between Hormonal Counterregulatory Responses and Cerebral Glucose Metabolism During Hypoglycemia.

John J Lee, Nadia Khoury, Angela M Shackleford, Suzanne Nelson, Hector Herrera, Jo Ann Antenor-Dorsey, Katherine Semenkovich, Joshua S Shimony, William J Powers, Philip E Cryer, Ana María Arbeláez,

Hypoglycemia is the most common complication of diabetes, causing morbidity and death. Recurrent hypoglycemia alters the cascade of physiological and behavioral responses that maintain euglycemia. The extent to which these responses are normally triggered by decreased whole-brain cerebral glucose metabolism (CMR<sub>glc</sub>) has not been resolved by previous studies. We measured ... Read more >>

Diabetes (Diabetes)
[2017, 66(12):2964-2972]

Cited: 2 times

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Nonstenotic carotid plaques: Stroke causation or guilt by association?

Ajay Gupta, William J Powers,

Neurology (Neurology)
[2016, 87(7):650-651]

Cited: 1 time

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Effect of High-Dose Simvastatin on Cerebral Blood Flow and Static Autoregulation in Subarachnoid Hemorrhage.

Michael N Diringer, Rajat Dhar, Michael Scalfani, Allyson R Zazulia, Michael Chicoine, William J Powers, Colin P Derdeyn,

<h4>Background</h4>Statins may promote vasodilation following subarachnoid hemorrhage (SAH) and improve the response to blood pressure elevation. We sought to determine whether simvastatin increases cerebral blood flow (CBF) and alters the response to induced hypertension after SAH.<h4>Methods</h4>Statin-naïve patients admitted <72 h after WFNS ≥2 aneurysmal SAH were randomly assigned to 80 mg simvastatin/day ... Read more >>

Neurocrit Care (Neurocritical care)
[2016, 25(1):56-63]

Cited: 15 times

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Pupil-sparing third nerve palsies and hemiataxia: Claude's and reverse Claude's syndrome.

James R Bateman, Pavan Murty, Michael Forbes, Kisha Young Collier, Danoushka Tememe, Octavio de Marchena, William J Powers,

We report two patients with midbrain infarction with pupil-sparing third nerve palsies and hemiataxia: one with contralateral ataxia (Claude's syndrome) and one with ipsilateral ataxia (which we refer to as reverse Claude's syndrome). We highlight the importance of a thorough neurologic evaluation with partial oculomotor palsies and describe, to our ... Read more >>

J Clin Neurosci (Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia)
[2016, 28:178-180]

Cited: 0 times

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Relative Mean Transit Time Predicts Subsequent Stroke in Symptomatic Carotid Occlusion.

Robert L Grubb, Colin P Derdeyn, Tom O Videen, David A Carpenter, William J Powers,

<h4>Background</h4>Mean transit time (MTT) measurements to assess cerebral hemodynamics are easily obtained by computed tomography and magnetic resonance imaging. We reviewed hemodynamic and clinical outcome data from the St. Louis Carotid Occlusion Study to determine if increased MTT was associated with an increased risk of stroke in patients with symptomatic ... Read more >>

J Stroke Cerebrovasc Dis (Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association)
[2016, 25(6):1421-1424]

Cited: 4 times

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Reperfusion Beyond 6 Hours Reduces Infarct Probability in Moderately Ischemic Brain Tissue.

Hongyu An, Andria L Ford, Cihat Eldeniz, Yasheng Chen, Katie D Vo, Hongtu Zhu, William J Powers, Weili Lin, Jin-Moo Lee,

<h4>Background and purpose</h4>We aimed to examine perfusion changes between 3 and 6 and 6 and 24 hours after stroke onset and their impact on tissue outcome.<h4>Methods</h4>Acute ischemic stroke patients underwent perfusion magnetic resonance imaging at 3, 6, and 24 hours after stroke onset and follow-up fluid-attenuated inversion recovery at 1 ... Read more >>

Stroke (Stroke)
[2016, 47(1):99-105]

Cited: 5 times

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Note on levels of clinical efficacy.

William J Powers,

Neurol Clin (Neurologic clinics)
[2015, 33(2):xv-xvii]

Cited: 0 times

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2015 American Heart Association/American Stroke Association Focused Update of the 2013 Guidelines for the Early Management of Patients With Acute Ischemic Stroke Regarding Endovascular Treatment: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association.

William J Powers, Colin P Derdeyn, José Biller, Christopher S Coffey, Brian L Hoh, Edward C Jauch, Karen C Johnston, S Claiborne Johnston, Alexander A Khalessi, Chelsea S Kidwell, James F Meschia, Bruce Ovbiagele, Dileep R Yavagal, ,

<h4>Purpose</h4>The aim of this guideline is to provide a focused update of the current recommendations for the endovascular treatment of acute ischemic stroke. When there is overlap, the recommendations made here supersede those of previous guidelines.<h4>Methods</h4>This focused update analyzes results from 8 randomized, clinical trials of endovascular treatment and other ... Read more >>

Stroke (Stroke)
[2015, 46(10):3020-3035]

Cited: 814 times

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