Full Text Journal Articles by
Author William Christopher Mathews

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Brief Report: Differences in Types of Myocardial Infarctions Among People Aging With HIV.

Heidi M Crane, Robin M Nance, Bridget M Whitney, Susan R Heckbert, Matthew Budoff, Kevin High, Alan Landay, Matthew Feinstein, Richard D Moore, William Christopher Mathews, Katerina Christopoulos, Michael S Saag, Amanda Willig, Joseph J Eron, Mari M Kitahata, Joseph A C Delaney, ,

<h4>Background</h4>Type 1 myocardial infarctions (T1MIs) result from atherosclerotic plaque instability, rupture, and/or erosion. Type 2 MIs (T2MIs) are secondary to causes such as sepsis and cocaine-induced vasospasm resulting in an oxygen demand-supply mismatch and are associated with higher mortality than T1MIs. T2MIs account for a higher proportion of MIs among ... Read more >>

J Acquir Immune Defic Syndr (Journal of acquired immune deficiency syndromes (1999))
[2021, 86(2):208-212]

Cited: 0 times

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Internalized HIV Stigma Is Associated With Concurrent Viremia and Poor Retention in a Cohort of US Patients in HIV Care.

Katerina A Christopoulos, Torsten B Neilands, Wendy Hartogensis, Elvin H Geng, John Sauceda, Michael J Mugavero, Heidi M Crane, Rob J Fredericksen, Richard D Moore, William Christopher Mathews, Kenneth H Mayer, Geetanjali Chander, Christopher B Hurt, Mallory O Johnson,

<h4>Background</h4>The relationship of internalized HIV stigma to key care cascade metrics in the United States is not well established using large-scale, geographically diverse data.<h4>Setting</h4>Center for AIDS Research Network of Integrated Clinical Systems (CNICS) cohort study.<h4>Methods</h4>Beginning in February 2016, we administered a yearly, validated 4-item internalized HIV stigma scale (response scale ... Read more >>

J Acquir Immune Defic Syndr (Journal of acquired immune deficiency syndromes (1999))
[2019, 82(2):116-123]

Cited: 4 times

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Virologic Failure Among People Living With HIV Initiating Dolutegravir-Based Versus Other Recommended Regimens in Real-World Clinical Care Settings.

Robin M Nance, Vani Vannappagari, Kimberly Smith, Catherine B Johannes, Brian Calingaert, Catherine W Saltus, Kenneth H Mayer, Bridget M Whitney, Benigno Rodriguez, Richard D Moore, Joseph J Eron, Elvin Geng, William Christopher Mathews, Michael J Mugavero, Michael S Saag, Mari M Kitahata, Joseph A C Delaney, Heidi M Crane,

<h4>Background</h4>Guidelines for initial antiretroviral treatment (ART) regimens have evolved, with integrase strand transfer inhibitors (INSTIs) increasingly prominent. Research on virologic failure (VF) with INSTI therapy is predominantly from clinical trials not care settings, especially for recently approved medications including dolutegravir. We compared outcomes among people living with HIV (PLWH) who ... Read more >>

J Acquir Immune Defic Syndr (Journal of acquired immune deficiency syndromes (1999))
[2019, 81(5):572-577]

Cited: 4 times

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Detecting Disengagement From HIV Care Before It Is Too Late: Development and Preliminary Validation of a Novel Index of Engagement in HIV Care.

Mallory O Johnson, Torsten B Neilands, Kimberly A Koester, Troy Wood, John A Sauceda, Samantha E Dilworth, Michael J Mugavero, Heidi M Crane, Rob J Fredericksen, Kenneth H Mayer, William C Mathews, Richard D Moore, Sonia Napravnik, Katerina A Christopoulos,

<h4>Background</h4>Engagement in care is critical to achieving and sustaining optimal benefits of efficacious antiretroviral therapies for HIV infection. Current metrics of engagement in care, including problematic patterns of retention in care, adherence to treatment, and viral suppression, are often detected late in the disengagement process. We sought to develop and ... Read more >>

J Acquir Immune Defic Syndr (Journal of acquired immune deficiency syndromes (1999))
[2019, 81(2):145-152]

Cited: 1 time

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Marijuana Use Is Not Associated With Changes in Opioid Prescriptions or Pain Severity Among People Living With HIV and Chronic Pain.

Jessica S Merlin, Dustin Long, William C Becker, Edward R Cachay, Katerina A Christopolous, Kasey R Claborn, Heidi M Crane, Eva Jennifer Edelman, Travis I Lovejoy, William Christopher Mathews, Benjamin J Morasco, Sonia Napravnik, Connall OʼCleirigh, Michael S Saag, Joanna L Starrels, Robert Gross, Jane M Liebschutz,

<h4>Background</h4>People living with HIV (PLWH) commonly report marijuana use for chronic pain, although there is limited empirical evidence to support its use. There is hope that marijuana may reduce prescription opioid use. Our objective was to investigate whether marijuana use among PLWH who have chronic pain is associated with changes ... Read more >>

J Acquir Immune Defic Syndr (Journal of acquired immune deficiency syndromes (1999))
[2019, 81(2):231-237]

Cited: 1 time

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Gonorrhoea and chlamydia in persons with HIV: number needed to screen.

Susan Tuddenham, Khalil G Ghanem, Kelly A Gebo, Richard D Moore, William Christopher Mathews, Allison Agwu, Kenneth Mayer, Christina Schumacher, Julia Raifman, Stephen A Berry,

<h4>Objectives</h4>Current guidelines recommend screening sexually active persons with HIV (PWH) for <i>Neisseria gonorrhoeae</i> (NG) and <i>Chlamydia trachomatis</i> (CT) at least annually. Yet, screening rates in many HIV clinics remain low. In this study, we estimated the number needed to screen (NNS) to detect a NG and/or CT infection at each ... Read more >>

Sex Transm Infect (Sexually transmitted infections)
[2019, 95(5):322-327]

Cited: 1 time

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HCV Screening and Treatment Uptake Among Patients in HIV Care During 2014-2015.

Daniel Radwan, Edward Cachay, Oluwaseun Falade-Nwulia, Richard D Moore, Ryan Westergaard, William Christopher Mathews, Judith Aberg, Laura Cheever, Kelly A Gebo, ,

<h4>Background</h4>Despite the high prevalence of hepatitis C virus (HCV) among persons living with HIV (PWH), the prevalence of HCV screening, treatment, and sustained virologic response (SVR) is unknown. This study aims to characterize the continuum of HCV screening and treatment among PWH in HIV care.<h4>Setting</h4>Adult patients enrolled at 12 sites ... Read more >>

J Acquir Immune Defic Syndr (Journal of acquired immune deficiency syndromes (1999))
[2019, 80(5):559-567]

Cited: 1 time

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Reduced Cancer Survival Among Adults With HIV and AIDS-Defining Illnesses Despite No Difference in Cancer Stage at Diagnosis.

Surbhi Grover, Fidel Desir, Yuezhou Jing, Rohini K Bhatia, Daniel M Trifiletti, Samuel Swisher-McClure, Julie Kobie, Richard D Moore, Charles S Rabkin, Michael J Silverberg, Kate Salters, William Christopher Mathews, Michael John Gill, Jennifer E Thorne, Jessica Castilho, Mari M Kitahata, Amy Justice, Michael A Horberg, Chad J Achenbach, Angel M Mayor, Keri N Althoff, ,

<h4>Background</h4>It is not known whether immune dysfunction is associated with increased risk of death after cancer diagnosis in persons with HIV (PWH). AIDS-defining illness (ADI) can signal significant immunosuppression. Our objective was to determine differences in cancer stage and mortality rates in PWH with and without history of ADI.<h4>Methods</h4>PWH with ... Read more >>

J Acquir Immune Defic Syndr (Journal of acquired immune deficiency syndromes (1999))
[2018, 79(4):421-429]

Cited: 3 times

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Gonorrhea and Chlamydia Case Detection Increased When Testing Increased in a Multisite US HIV Cohort, 2004-2014.

Julia R Raifman, Kelly A Gebo, William Christopher Mathews, Philip Todd Korthuis, Khalil G Ghanem, Judith A Aberg, Richard D Moore, Ank E Nijhawan, Anne K Monroe, Stephen A Berry, ,

<h4>Objectives</h4>Annual screening for gonorrhea [Neisseria gonorrhoeae (NG)] and chlamydia [Chlamydia trachomatis (CT)] is recommended for all sexually active persons living with HIV but is poorly implemented. Studies demonstrating no increases in NG and/or CT (NG/CT) case detection in clinics that successfully expanded NG/CT screening raise questions about this broad screening ... Read more >>

J Acquir Immune Defic Syndr (Journal of acquired immune deficiency syndromes (1999))
[2017, 76(4):409-416]

Cited: 6 times

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Relationship between ever reporting depressive symptoms and all-cause mortality in a cohort of HIV-infected adults in routine care.

Angela M Bengtson, Brian W Pence, Richard Moore, Matthew J Mimiaga, William Christopher Mathews, Amy Heine, Bradley N Gaynes, Sonia Napravnik, Katerina Christopoulos, Heidi M Crane, Michael J Mugavero,

<h4>Objective</h4>The aim of this study was to assess whether ever reporting depressive symptoms affects mortality in the modern HIV treatment era.<h4>Design</h4>A cohort study of HIV-infected adults in routine clinical care at seven sites in the USA.<h4>Methods</h4>We examined the effect of ever reporting depressive symptoms on all-cause mortality using data from ... Read more >>

AIDS (AIDS (London, England))
[2017, 31(7):1009-1016]

Cited: 4 times

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HIV primary care providers--Screening, knowledge, attitudes and behaviors related to alcohol interventions.

Geetanjali Chander, Anne K Monroe, Heidi M Crane, Heidi E Hutton, Michael S Saag, Karen Cropsey, Joseph J Eron, E Byrd Quinlivan, Elvin Geng, William Christopher Mathews, Stephen Boswell, Benigno Rodriquez, Megan Ellison, Mari M Kitahata, Richard D Moore, Mary E McCaul,

<h4>Background</h4>Alcohol has particularly harmful health effects in HIV-infected patients; therefore, HIV clinics are an important setting for integration of brief alcohol intervention and alcohol pharmacotherapy to improve patient outcomes. Current practices of alcohol screening, counseling, and prescription of pharmacotherapy by HIV providers are unknown.<h4>Methods</h4>We conducted a cross-sectional survey of HIV ... Read more >>

Drug Alcohol Depend (Drug and alcohol dependence)
[2016, 161:59-66]

Cited: 17 times

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Effects of Referral Bias on Estimates of Anal Intraepithelial Neoplasia Progression and Regression Rates in a 3-State Markov Model.

William Christopher Mathews, Edward Rafael Cachay, Wollelaw Agmas, Christopher Jackson,

The study aim is to compare anal intraepithelial neoplasia (AIN) progression and regression rates in a cytology inception cohort to estimates based on the subcohort referred for ≥1 high-resolution anoscopies (HRAs).A cytology-based retrospective cohort was assembled including the anal cytology histories and invasive anal cancer (IAC) outcomes of all HIV-infected ... Read more >>

Medicine (Baltimore) (Medicine)
[2015, 94(35):e1476]

Cited: 2 times

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Brief Report: Gonorrhea and Chlamydia Testing Increasing but Still Lagging in HIV Clinics in the United States.

Stephen A Berry, Khalil G Ghanem, William Christopher Mathews, Philip Todd Korthuis, Baligh R Yehia, Allison L Agwu, Christoph U Lehmann, Richard D Moore, Sara L Allen, Kelly A Gebo, ,

Screening persons living with HIV for gonorrhea and chlamydia has been recommended since 2003. We compared annual gonorrhea/chlamydia testing to syphilis and lipid testing among 19,368 adults (41% men who have sex with men, 30% heterosexual men, and 29% women) engaged in HIV care. In 2004, 22%, 62%, and 70% ... Read more >>

J Acquir Immune Defic Syndr (Journal of acquired immune deficiency syndromes (1999))
[2015, 70(3):275-279]

Cited: 9 times

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Human papillomavirus, anal cancer, and screening considerations among HIV-infected individuals.

Edward R Cachay, William Christopher Mathews,

Invasive anal cancer has become an important cause of non AIDS-related cancer among HIV-infected individuals. Human papillomavirus is the main etiological agent. This review explains the pathophysiologic role of human papillomavirus in the development of invasive anal cancer, summarizes recent epidemiological trends of invasive anal cancer, and reviews the evidence ... Read more >>

AIDS Rev (AIDS reviews)
[2013, 15(2):122-133]

Cited: 19 times

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Structures of care in the clinics of the HIV Research Network.

Baligh R Yehia, Kelly A Gebo, Perrin B Hicks, P Todd Korthuis, Richard D Moore, Michelande Ridore, William Christopher Mathews, ,

As the HIV epidemic has evolved to become a chronic, treatable condition the focus of HIV care has shifted from the inpatient to the outpatient arena. The optimal structure of HIV care in the outpatient setting is unknown. Using the HIV Research Network (HIVRN), a federally sponsored consortium of 21 ... Read more >>

AIDS Patient Care STDS (AIDS patient care and STDs)
[2008, 22(12):1007-1013]

Cited: 34 times

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Supporting Positive Living and Sexual Health (SPLASH): a clinician and behavioral counselor risk-reduction intervention in a university-based HIV clinic.

María Luisa Zúñiga, Heather Baldwin, Daniel Uhler, Jesse Brennan, Alisa María Olshefsky, Erin Oliver, William Christopher Mathews,

Effective HIV prevention interventions with HIV-positive persons are paramount to stemming the rate of new infections. This paper describes an HIV-clinic-based demonstration project aimed at decreasing patient HIV-transmission risk behaviors and sexually transmitted infections. Systematic, computer-assisted assessment of patient risk aided primary care providers in delivering prevention messages. Patients at ... Read more >>

AIDS Behav (AIDS and behavior)
[2007, 11(5 Suppl):S58-71]

Cited: 4 times

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Measurement characteristics of anal cytology, histopathology, and high-resolution anoscopic visual impression in an anal dysplasia screening program.

William Christopher Mathews, Amy Sitapati, Joseph C Caperna, R Edward Barber, Alyssa Tugend, Unyeong Go,

<h4>Background</h4>The study aims were (1) to estimate agreement between consecutive anal cytologic examinations, between concurrent cytologic examination and histopathology, and between high-resolution anoscopy (HRA) visual impression and histopathology and (2) to estimate the prevalence of severe dysplasia by concurrent cytologic category.<h4>Methods</h4>Prospective study of HIV-infected patients receiving anal dysplasia screening as ... Read more >>

J Acquir Immune Defic Syndr (Journal of acquired immune deficiency syndromes (1999))
[2004, 37(5):1610-1615]

Cited: 54 times

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