Full Text Journal Articles by
Author William A Knaus

Advertisement

Find full text journal articles








The authors reply.

Andrew A Kramer, Jack E Zimmerman, William A Knaus,

Crit Care Med (Critical care medicine)
[2021, 49(11):e1177]

Cited: 0 times

View full text PDF listing >>



Severity of Illness and Predictive Models in Society of Critical Care Medicine's First 50 Years: A Tale of Concord and Conflict.

Andrew A Kramer, Jack E Zimmerman, William A Knaus,

Crit Care Med (Critical care medicine)
[2021, 49(5):728-740]

Cited: 0 times

View full text PDF listing >>



Advertisement

A Case-Control Study to Add Volumetric or Clinical Mammographic Density into the Tyrer-Cuzick Breast Cancer Risk Model.

Adam R Brentnall, Wendy F Cohn, William A Knaus, Martin J Yaffe, Jack Cuzick, Jennifer A Harvey,

<h4>Background</h4>Accurate breast cancer risk assessment for women attending routine screening is needed to guide screening and preventive interventions. We evaluated the accuracy of risk predictions from both visual and volumetric mammographic density combined with the Tyrer-Cuzick breast cancer risk model.<h4>Methods</h4>A case-control study (474 patient participants and 2243 healthy control participants) ... Read more >>

J Breast Imaging (Journal of breast imaging)
[2019, 1(2):99-106]

Cited: 8 times

View full text PDF listing >>



New Phenotypes for Sepsis: The Promise and Problem of Applying Machine Learning and Artificial Intelligence in Clinical Research.

William A Knaus, Richard D Marks,

JAMA (JAMA)
[2019, 321(20):1981-1982]

Cited: 7 times

View full text PDF listing >>



What Do Women Know About Breast Density? Results From a Population Survey of Virginia Women.

Thomas M Guterbock, Wendy F Cohn, Deborah L Rexrode, Casey M Eggleston, Melissa Dean-McKinney, Wendy M Novicoff, Martin J Yaffe, William A Knaus, Jennifer A Harvey,

<h4>Purpose</h4>Breast density reduces the sensitivity of mammography and is a moderate independent risk factor for breast cancer. Virginia is one of 24 states that currently require notification of patients when they have dense breasts. However, little is known about what women in the general population know about breast density. This ... Read more >>

J Am Coll Radiol (Journal of the American College of Radiology : JACR)
[2017, 14(1):34-44]

Cited: 5 times

View full text PDF listing >>



Initial clinical validation of Health Heritage, a patient-facing tool for personal and family history collection and cancer risk assessment.

Leigh A Baumgart, Kristen J Vogel Postula, William A Knaus,

Personal and family health histories remain important independent risk factors for cancer; however they are currently not being well collected or used effectively. Health Heritage was designed to address this need. The purpose of this study was to validate the ability of Health Heritage to identify patients appropriate for further ... Read more >>

Fam Cancer (Familial cancer)
[2016, 15(2):331-339]

Cited: 5 times

View full text PDF listing >>



Comparative effectiveness research in cancer genomics and precision medicine: current landscape and future prospects.

Naoko I Simonds, Muin J Khoury, Sheri D Schully, Katrina Armstrong, Wendy F Cohn, David A Fenstermacher, Geoffrey S Ginsburg, Katrina A B Goddard, William A Knaus, Gary H Lyman, Scott D Ramsey, Jianfeng Xu, Andrew N Freedman,

A major promise of genomic research is information that can transform health care and public health through earlier diagnosis, more effective prevention and treatment of disease, and avoidance of drug side effects. Although there is interest in the early adoption of emerging genomic applications in cancer prevention and treatment, there ... Read more >>

J Natl Cancer Inst (Journal of the National Cancer Institute)
[2013, 105(13):929-936]

Cited: 20 times

View full text PDF listing >>



Changes in hospital mortality for United States intensive care unit admissions from 1988 to 2012.

Jack E Zimmerman, Andrew A Kramer, William A Knaus,

<h4>Introduction</h4>A decrease in disease-specific mortality over the last twenty years has been reported for patients admitted to United States (US) hospitals, but data for intensive care patients are lacking. The aim of this study was to describe changes in hospital mortality and case-mix using clinical data for patients admitted to ... Read more >>

Crit Care (Critical care (London, England))
[2013, 17(2):R81]

Cited: 137 times

View full text PDF listing >>



Building the evidence base for decision making in cancer genomic medicine using comparative effectiveness research.

Katrina A B Goddard, William A Knaus, Evelyn Whitlock, Gary H Lyman, Heather Spencer Feigelson, Sheri D Schully, Scott Ramsey, Sean Tunis, Andrew N Freedman, Muin J Khoury, David L Veenstra,

The clinical utility is uncertain for many cancer genomic applications. Comparative effectiveness research (CER) can provide evidence to clarify this uncertainty. The aim of this study was to identify approaches to help stakeholders make evidence-based decisions and to describe potential challenges and opportunities in using CER to produce evidence-based guidance. ... Read more >>

Genet Med (Genetics in medicine : official journal of the American College of Medical Genetics)
[2012, 14(7):633-642]

Cited: 23 times

View full text PDF listing >>



The Acute Physiology and Chronic Health Evaluation II. Article of Knaus et al with expert commentary by Dr Derek Angus.

Ali Al-Khafaji, Derek C Angus, William A Knaus,

J Crit Care (Journal of critical care)
[2007, 22(1):85-88]

Cited: 4 times

View full text PDF listing >>



Relemed: sentence-level search engine with relevance score for the MEDLINE database of biomedical articles.

Mir S Siadaty, Jianfen Shu, William A Knaus,

<h4>Background</h4>Receiving extraneous articles in response to a query submitted to MEDLINE/PubMed is common. When submitting a multi-word query (which is the majority of queries submitted), the presence of all query words within each article may be a necessary condition for retrieving relevant articles, but not sufficient. Ideally a relationship between ... Read more >>

BMC Med Inform Decis Mak (BMC medical informatics and decision making)
[2007, 7:1]

Cited: 42 times

View full text PDF listing >>



Locating previously unknown patterns in data-mining results: a dual data- and knowledge-mining method.

Mir S Siadaty, William A Knaus,

<h4>Background</h4>Data mining can be utilized to automate analysis of substantial amounts of data produced in many organizations. However, data mining produces large numbers of rules and patterns, many of which are not useful. Existing methods for pruning uninteresting patterns have only begun to automate the knowledge acquisition step (which is ... Read more >>

BMC Med Inform Decis Mak (BMC medical informatics and decision making)
[2006, 6:13]

Cited: 6 times

View full text PDF listing >>



Data mining and clinical data repositories: Insights from a 667,000 patient data set.

Irene M Mullins, Mir S Siadaty, Jason Lyman, Ken Scully, Carleton T Garrett, W Greg Miller, Rudy Muller, Barry Robson, Chid Apte, Sholom Weiss, Isidore Rigoutsos, Daniel Platt, Simona Cohen, William A Knaus,

Clinical repositories containing large amounts of biological, clinical, and administrative data are increasingly becoming available as health care systems integrate patient information for research and utilization objectives. To investigate the potential value of searching these databases for novel insights, we applied a new data mining approach, HealthMiner, to a large ... Read more >>

Comput Biol Med (Computers in biology and medicine)
[2006, 36(12):1351-1377]

Cited: 46 times

View full text PDF listing >>



Designing trials and deciding on therapy in complex diseases: what can we do to improve?

William A Knaus,

Med Decis Making (Medical decision making : an international journal of the Society for Medical Decision Making)
[2005, 25(4):366-369]

Cited: 0 times

View full text PDF listing >>



Impact of patient distance to radiation therapy on mastectomy use in early-stage breast cancer patients.

Anneke T Schroen, David R Brenin, Maria D Kelly, William A Knaus, Craig L Slingluff,

<h4>Purpose</h4>Treatment access underlies quality cancer care. We hypothesize that mastectomy rates in a rural state are independently influenced by distance to radiation therapy (XRT) and by changing XRT access through opening new facilities.<h4>Patients and methods</h4>Early-stage breast cancer patients diagnosed from 1996 to 2000 were identified in the Virginia state registry. ... Read more >>

J Clin Oncol (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)
[2005, 23(28):7074-7080]

Cited: 133 times

View full text PDF listing >>



Improving intensive care performance: complex paths to simple truths.

William A Knaus,

Mayo Clin Proc (Mayo Clinic proceedings)
[2005, 80(2):164-165]

Cited: 2 times

View full text PDF listing >>



Outcomes up to 5 years after severe, acute respiratory failure.

Allan Garland, Neal V Dawson, Irene Altmann, Charles L Thomas, Russell S Phillips, Joel Tsevat, Norman A Desbiens, Paul E Bellamy, William A Knaus, Alfred F Connors, ,

<h4>Study objective</h4>To use an existing database from a large cohort study with follow-up as long as 5.5 years to assess the extended prognosis of patients who survived their hospitalizations for severe acute respiratory failure (ARF).<h4>Design, setting, and patients</h4>Secondary analysis of an inception cohort of 1,722 patients with ARF requiring mechanical ... Read more >>

Chest (Chest)
[2004, 126(6):1897-1904]

Cited: 30 times

View full text PDF listing >>



CXC chemokine receptor 3 expression by activated CD8+ T cells is associated with survival in melanoma patients with stage III disease.

Irene M Mullins, Craig L Slingluff, Jae K Lee, Courtney F Garbee, Jianfen Shu, Sara G Anderson, Melanie E Mayer, William A Knaus, David W Mullins,

Despite the presence of tumor Ag-specific CD8(+) T cells in the peripheral blood, metastatic melanoma often evades immune-mediated destruction. Even after therapeutic efforts to expand Ag-specific T-cell populations, the correlation between magnitude of response and clinical efficacy has been weak. Because the migratory phenotype of tumor Ag-specific effector T cells ... Read more >>

Cancer Res (Cancer research)
[2004, 64(21):7697-7701]

Cited: 88 times

View full text PDF listing >>



GeneX Va: VBC open source microarray database and analysis software.

Jae K Lee, Tom Laudeman, Jodi Kanter, Teela James, Mir S Siadaty, William A Knaus, Alyson Prorok, Yongde Bao, Brad Freeman, Daniela Puiu, Li Min Wen, Gregory A Buck, Karen Schlauch, Jennifer Weller, Jay W Fox,

Developed by the Virginia Bioinformatics Consortium (VBC), GeneX Va is an open source, freeware database and bioinformatics analysis software for archiving and analyzing Affymetrix GeneChip data. It provides an integrated framework for management, documentation, and analysis of microarray experiments and data to support a range of users, from individual research ... Read more >>

Biotechniques (BioTechniques)
[2004, 36(4):634-8, 640, 642]

Cited: 5 times

View full text PDF listing >>



Probabilistic thinking and intensive care: a world view.

William A Knaus,

Crit Care Med (Critical care medicine)
[2004, 32(5):1231-1232]

Cited: 2 times

View full text PDF listing >>



A user-centered model for web site design: needs assessment, user interface design, and rapid prototyping.

Mable B Kinzie, Wendy F Cohn, Marti F Julian, William A Knaus,

As the Internet continues to grow as a delivery medium for health information, the design of effective Web sites becomes increasingly important. In this paper, the authors provide an overview of one effective model for Web site design, a user-centered process that includes techniques for needs assessment, goal/task analysis, user ... Read more >>

J Am Med Inform Assoc (Journal of the American Medical Informatics Association : JAMIA)
[2002, 9(4):320-330]

Cited: 43 times

View full text PDF listing >>



APACHE 1978-2001: the development of a quality assurance system based on prognosis: milestones and personal reflections.

William A Knaus,

Arch Surg (Archives of surgery (Chicago, Ill. : 1960))
[2002, 137(1):37-41]

Cited: 28 times

View full text PDF listing >>



Securing the HealthHeritage Web, A Family Health History Web Site

James R Barrett, William D. Woolfolk, Douglas P. Wagner, Anthony J. Wenzel, William A Knaus,

Proc AMIA Symp (Proceedings. AMIA Symposium)
[2000, :961-961]

Cited: 0 times

View full text PDF listing >>





Advertisement


Disclaimer

0.8273 s