Full Text Journal Articles by
Author Wenxia Zhang

Advertisement

Find full text journal articles






Resistance phenotype and molecular epidemiology of Carbapenem-resistant Klebsiella pneumoniae isolates in Shanghai

Jue Zhang, Wenxia Zhang, Hongyou Chen, Chen Chen, Junhao Chen, Lingxia Li, Min Chen,

Abstract Background: The emergence and wide global spread of carbapenem-resistant Klebsiella pneumoniae (CRKP) isolates are of great concern, and the aim of this study was to investigate drug resistance, molecular epidemiology, and genetic relationship of CRKP isolates from patients in Shanghai, China. Methods: A retrospective study was conducted from April ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



miR-30a-5p Inhibits Proliferation and Migration of Lung Squamous Cell Carcinoma Cells by Targeting FOXD1.

Chunhua Chen, Junhua Tang, Shan Xu, Wenxia Zhang, Hanliang Jiang,

Objective:To investigate the mechanism of miR-30a-5p inhibiting proliferation and migration of lung squamous cell carcinoma (LSCC) cells by targeting FOXD1. Methods:Bioinformatics was used to analyze differentially expressed genes in the TCGA_LUSC database. qRT-PCR was used to detect the expression levels of miR-30a-5p and FOXD1 in human normal lung epithelial cell ... Read more >>

Biomed Res Int (BioMed research international)
[2020, 2020:2547902]

Cited: 0 times

View full text PDF listing >>



Advertisement

Pyruvate Kinase M2 Promotes the Activation of Dendritic Cells by Enhancing IL-12p35 Expression.

Xin Jin, Wenxia Zhang, Yang Wang, Jia Liu, Fengqi Hao, Yunlong Li, Miaomiao Tian, Hengyao Shu, Jiaxin Dong, Yunpeng Feng, Min Wei,

Dendritic cells (DCs) play a central role in both innate and adaptive immunity. Emerging evidence has demonstrated metabolic reprogramming during DC activation. However, how DC activation is linked with metabolic reprogramming remains unclear. Here we show that pyruvate kinase M2 (PKM2), the rate-limiting enzyme in the last step of glycolysis, ... Read more >>

Cell Rep (Cell Reports)
[2020, 31(8):107690]

Cited: 0 times

View full text PDF listing >>



Validation of novel automatic ultra-wideband radar for sleep apnea detection.

Yong Zhou, Degui Shu, Hangdi Xu, Yuanhua Qiu, Pan Zhou, Wenjing Ruan, Guangyue Qin, Joy Jin, Hao Zhu, Kejing Ying, Wenxia Zhang, Enguo Chen,

Background:To validate the accuracy of ultra-wideband (UWB) wireless radar for the screening diagnosis of sleep apnea. Methods:One hundred and seventy-six qualified participants were successfully recruited. Apnea-hypopnea index (AHI) results from polysomnography (PSG) were reviewed by physicians, while the radar device automatically calculated AHI values with an embedded chip. All results ... Read more >>

J Thorac Dis (Journal of thoracic disease)
[2020, 12(4):1286-1295]

Cited: 0 times

View full text PDF listing >>



LRP6 is involved in the proliferation, migration and invasion of trophoblast cells via miR‑346.

Lu Zhang, Huihui Li, Mingbao Li, Wenxia Zhang, Zhou Yang, Shuquan Zhang,

Low‑density lipoprotein receptor‑related protein 6 (LRP6) promotes metastasis in numerous types of cancer; however, its role in trophoblast cells has been less frequently reported. In the present study, the effects of up‑ and downregulation of LRP6 on trophoblast cells were investigated accordingly. The study aimed to develop a therapeutic target for ... Read more >>

Int. J. Mol. Med. (International journal of molecular medicine)
[2020, :]

Cited: 0 times

View full text PDF listing >>



RNA based mNGS approach identifies a novel human coronavirus from two individual pneumonia cases in 2019 Wuhan outbreak.

Liangjun Chen, Weiyong Liu, Qi Zhang, Ke Xu, Guangming Ye, Weichen Wu, Ziyong Sun, Fang Liu, Kailang Wu, Bo Zhong, Yi Mei, Wenxia Zhang, Yu Chen, Yirong Li, Mang Shi, Ke Lan, Yingle Liu,

From December 2019, an outbreak of unusual pneumonia was reported in Wuhan with many cases linked to Huanan Seafood Market that sells seafood as well as live exotic animals. We investigated two patients who developed acute respiratory syndromes after independent contact history with this market. The two patients shared common ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2020, 9(1):313-319]

Cited: 0 times

View full text PDF listing >>



13.34 % Efficiency Non-Fullerene All-Small-Molecule Organic Solar Cells Enabled by Modulating the Crystallinity of Donors via a Fluorination Strategy.

Jinfeng Ge, Lingchao Xie, Ruixiang Peng, Billy Fanady, Jiaming Huang, Wei Song, Tingting Yan, Wenxia Zhang, Ziyi Ge,

Non-fullerene all-small-molecule organic solar cells (NFSM-OSCs) have shown potential as OSCs, owing to their high purity, easy synthesis and good reproducibility. However, challenges in the modulation of phase separation morphology have limited their development. Herein, two novel small molecular donors, BTEC-1F and BTEC-2F, derived from the small molecule DCAO3TBDTT, are ... Read more >>

Angew. Chem. Int. Ed. Engl. (Angewandte Chemie (International ed. in English))
[2020, 59(7):2808-2815]

Cited: 0 times

View full text PDF listing >>



Improved Efficiency in All-Small-Molecule Organic Solar Cells with Ternary Blend of Nonfullerene Acceptor and Chlorinated and Nonchlorinated Donors.

Jinfeng Ge, Qiang Wei, Ruixiang Peng, Erjun Zhou, Tingting Yan, Wei Song, Wenxia Zhang, Xiaoa Zhang, Shengling Jiang, Ziyi Ge,

Ternary nonfullerene all-small-molecule organic solar cells (NFSM-OSCs) were developed by incorporating a nonfullerene acceptor (IDIC) and two structurally similar small molecular donors (SM and SM-Cl), where SM-Cl is a novel small molecular donor derived from the reported molecular donor SM. When doping 10% SM-Cl in the SM:IDIC binary system, the ... Read more >>

ACS Appl Mater Interfaces (ACS applied materials & interfaces)
[2019, 11(47):44528-44535]

Cited: 0 times

View full text PDF listing >>



Systematic comparison of hUC-MSCs at various passages reveals the variations of signatures and therapeutic effect on acute graft-versus-host disease.

Qinjun Zhao, Leisheng Zhang, Yimeng Wei, Hao Yu, Linglin Zou, Jiali Huo, Hongju Yang, Baoquan Song, Teng Wei, Dan Wu, Wenxia Zhang, Lei Zhang, Dengke Liu, Zongjin Li, Ying Chi, Zhibo Han, Zhongchao Han,

BACKGROUND:Mesenchymal stem cells are heterogenous populations with hematopoietic supporting and immunomodulating capacities. Enormous studies have focused on their preclinical or clinical therapeutic effects, yet the systematic study of continuous in vitro passages on signatures and functions of UC-MSCs at both the cellular and molecular levels is still lacking. METHODS:In this ... Read more >>

Stem Cell Res Ther (Stem Cell Research & Therapy)
[2019, 10(1):354]

Cited: 0 times

View full text PDF listing >>



Novel role of sex-determining region Y-box 7 (SOX7) in tumor biology and cardiovascular developmental biology.

Wei Hu, Yuehu Han, Wenwen Yang, Baoping Xu, Wenxia Zhang, Zhenxiao Jin, Fulin Chen,

The sex-determining region Y-box 7 (Sox7) is an important member of the SOX F family, which is characterized by a high-mobility-group DNA-binding domain. Previous studies have demonstrated the role of SOX7 in cardiovascular development. SOX7 expression could be detected in normal adult tissues. Furthermore, the expression levels of SOX7 were ... Read more >>

Semin. Cancer Biol. (Seminars in cancer biology)
[2019, :]

Cited: 0 times

View full text PDF listing >>



JNKi- and DAC-programmed mesenchymal stem/stromal cells from hESCs facilitate hematopoiesis and alleviate hind limb ischemia.

Yimeng Wei, Huixing Hou, Leisheng Zhang, Nianhuan Zhao, Chengwen Li, Jiali Huo, Ying Liu, Wenxia Zhang, Zongjin Li, Dengke Liu, Zhibo Han, Lei Zhang, Baoquan Song, Ying Chi, Zhongchao Han,

BACKGROUND:Mesenchymal stem/stromal cells (MSCs) derived from human embryonic stem cells (hESCs) are attractive for their hematopoietic-supporting or potential therapeutic effects. However, procedures for high-effective and scalable generation of MSCs from hESCs within 2 weeks are still unestablished, which also hinder the development and mechanism study of mesengenesis. METHODS:In this study, we ... Read more >>

Stem Cell Res Ther (Stem cell research & therapy)
[2019, 10(1):186]

Cited: 1 time

View full text PDF listing >>



Corrigendum: A long-term demasculinization of X-linked intergenic noncoding RNAs in.

Ge Gao, Maria D. Vibranovski, Li Zhang, Zheng Li, Min Liu, Yong E. Zhang, Xinmin Li, Wenxia Zhang, Qichang Fan, Nicholas W. VanKuren, Manyuan Long, Liping Wei,

Genome Res. (Genome research)
[2019, 29(9):15661-15661]

Cited: 0 times

View full text PDF listing >>



Current status of oxacillin-susceptible mecA-positive Staphylococcus aureus infection in Shanghai, China: A multicenter study

Junlan Liu, Tianming Li, Ni Zhong, Xing Wang, Jie Jiang, Wenxia Zhang, Rong Tang, Yinjuan Guo, Yun Liu, Jiang Hu, Lihua He, Jin Tang, Wenjuan Wu, Min Li,

Abstract The worldwide reported oxacillin-susceptible mecA -positive Staphylococcus aureus (OS-MRSA) represents a distinctly important challenge to detection and treatment of MRSA, but finite data on current status of OS-MRSA infection in Chinese hospitals are available. The present multicenter study carried out a battery of phenotypic susceptibility tests as well as ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Study of In Vitro Synergistic Bactericidal Activity of Dual β-Lactam Antibiotics Against KPC-2-Producing Klebsiella pneumoniae.

Wenxia Zhang, Yan Guo, Yang Yang, Dong Dong, Yonggui Zheng, Demei Zhu, Fupin Hu,

Objectives: To study the in vitro synergistic bactericidal activity of dual β-lactam antibiotics against KPC-2-producing Klebsiella pneumoniae and to explore the new therapeutic regimens for infections caused by carbapenem-resistant strains. Materials and Methods: The antimicrobial susceptibility testing of imipenem, meropenem, ceftazidime, and clavulanic acid on 40 clinically isolated strains of ... Read more >>

Microb. Drug Resist. (Microbial drug resistance (Larchmont, N.Y.))
[2020, 26(3):204-210]

Cited: 0 times

View full text PDF listing >>



Heritability of human visual contour integration-an integrated genomic study.

Zijian Zhu, Biqing Chen, Ren Na, Wan Fang, Wenxia Zhang, Qin Zhou, Shanbi Zhou, Han Lei, Ailong Huang, Tingmei Chen, Dongsheng Ni, Yuping Gu, Jianing Liu, Yi Rao, Fang Fang,

Contour integration, a key visual function to deal with occlusion and discontinuity in natural scenes, is essential to human survival. However, individuals are not equally well equipped with this ability. In particular, contour integration deficiencies are commonly detected in patients with mental disorders, especially schizophrenia. To understand the underlying sources ... Read more >>

Eur. J. Hum. Genet. (European Journal of Human Genetics)
[2019, 27(12):1867-1875]

Cited: 0 times

View full text PDF listing >>



Dietary Supplementation with Sea Bass (Lateolabrax maculatus) Ameliorates Ulcerative Colitis and Inflammation in Macrophages through Inhibiting Toll-Like Receptor 4-Linked Pathways.

Jiali Chen, Muthukumaran Jayachandran, Wenxia Zhang, Lingyuqing Chen, Bin Du, Zhiling Yu, Baojun Xu,

Sea bass (Lateolabrax maculatus) is a kind of food material commonly consumed in daily life. In traditional Chinese medicinal books, it has been indicated that sea bass can be applied for managing many inflammation-associated conditions. However, the studies on the pharmacological mechanisms of inflammation of sea bass remain scarce. Hence, ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2019, 20(12):]

Cited: 0 times

View full text PDF listing >>



Chemoconnectomics: Mapping Chemical Transmission in Drosophila.

Bowen Deng, Qi Li, Xinxing Liu, Yue Cao, Bingfeng Li, Yongjun Qian, Rui Xu, Renbo Mao, Enxing Zhou, Wenxia Zhang, Juan Huang, Yi Rao,

We define the chemoconnectome (CCT) as the entire set of neurotransmitters, neuromodulators, neuropeptides, and their receptors underlying chemotransmission in an animal. We have generated knockout lines of Drosophila CCT genes for functional investigations and knockin lines containing Gal4 and other tools for examining gene expression and manipulating neuronal activities, with ... Read more >>

Neuron (Neuron)
[2019, 101(5):876-893.e4]

Cited: 2 times

View full text PDF listing >>



D-Serine made by serine racemase in Drosophila intestine plays a physiological role in sleep.

Xihuimin Dai, Enxing Zhou, Wei Yang, Xiaohui Zhang, Wenxia Zhang, Yi Rao,

Natural D-serine (D-Ser) has been detected in animals more than two decades ago, but little is known about the physiological functions of D-Ser. Here we reveal sleep regulation by endogenous D-Ser. Sleep was decreased in mutants defective in D-Ser synthesis or its receptor the N-methyl-D-aspartic receptor 1 (NMDAR1), but increased in ... Read more >>

Nat Commun (Nature communications)
[2019, 10(1):1986]

Cited: 2 times

View full text PDF listing >>



Decitabine improves platelet recovery by down-regulating IL-8 level in MDS/AML patients with thrombocytopenia.

Wenxia Zhang, Cuicui Liu, Dan Wu, Chen Liang, Leisheng Zhang, Qiuqiu Zhang, Yiying Liu, Meijuan Xia, Hongtao Wang, Pei Su, Sizhou Feng, Mingzhe Han, Jiaxi Zhou, Fuxu Wang, Erlie Jiang,

Blood Cells Mol. Dis. (Blood cells, molecules & diseases)
[2019, 76:66-71]

Cited: 2 times

View full text PDF listing >>



In vitro and in vivo bactericidal activity of ceftazidime-avibactam against Carbapenemase-producing Klebsiella pneumoniae.

Wenxia Zhang, Yan Guo, Jiayin Li, Yiyuan Zhang, Yang Yang, Dong Dong, Demei Zhu, Ping He, Fupin Hu,

Background:In recent years, the incidence of carbapenem-resistant Enterobacteriaceae (CRE) infections has increased rapidly. Since the CRE strain is usually resistant to most of antimicrobial agents, patients with this infection are often accompanied by a high mortality. Therefore, it instigates a severe challenge the clinical management of infection. In this study, ... Read more >>

Antimicrob Resist Infect Control (Antimicrobial resistance and infection control)
[2018, 7:142]

Cited: 1 time

View full text PDF listing >>



Cognitive Impairment and Personality Traits in Epilepsy: Characterization and Risk Factor Analysis.

Xue Wang, Yudan Lv, Wenxia Zhang, Hongmei Meng,

Cognitive impairment and personality disorders are severe comorbidities commonly observed in patients with epilepsy, and together they decrease the quality of patients' life. This study aimed to evaluate cognitive function and personality traits in patients with epilepsy with the Wechsler Adult Intelligence Scale-Chinese revised and Eysenck Personality Questionnaire and investigate ... Read more >>

J. Nerv. Ment. Dis. (The Journal of nervous and mental disease)
[2018, 206(10):794-799]

Cited: 0 times

View full text PDF listing >>



Genomic Analyses of Visual Cognition: Perceptual Rivalry and Top-Down Control.

Biqing Chen, Zijian Zhu, Ren Na, Wan Fang, Wenxia Zhang, Qin Zhou, Shanbi Zhou, Han Lei, Ailong Huang, Tingmei Chen, Dongsheng Ni, Yuping Gu, Jianing Liu, Fang Fang, Yi Rao,

Visual cognition in humans has traditionally been studied with cognitive behavioral methods and brain imaging, but much less with genetic methods. Perceptual rivalry, an important phenomenon in visual cognition, is the spontaneous perceptual alternation that occurs between two distinct interpretations of a physically constant visual stimulus (e.g., binocular rivalry stimuli) ... Read more >>

J. Neurosci. (The Journal of neuroscience : the official journal of the Society for Neuroscience)
[2018, 38(45):9668-9678]

Cited: 2 times

View full text PDF listing >>



Reduced exposure to extreme precipitation from 0.5 °C less warming in global land monsoon regions.

Wenxia Zhang, Tianjun Zhou, Liwei Zou, Lixia Zhang, Xiaolong Chen,

The Paris Agreement set a goal to keep global warming well below 2 °C and pursue efforts to limit it to 1.5 °C. Understanding how 0.5 °C less warming reduces impacts and risks is key for climate policies. Here, we show that both areal and population exposures to dangerous extreme precipitation events (e.g., ... Read more >>

Nat Commun (Nature communications)
[2018, 9(1):3153]

Cited: 0 times

View full text PDF listing >>



Multi-level genomic analyses suggest new genetic variants involved in human memory.

Zijian Zhu, Biqing Chen, Hongming Yan, Wan Fang, Qin Zhou, Shanbi Zhou, Han Lei, Ailong Huang, Tingmei Chen, Tianming Gao, Liang Chen, Jieyu Chen, Dongsheng Ni, Yuping Gu, Jianing Liu, Wenxia Zhang, Yi Rao,

Development of high-throughput genotyping platforms provides an opportunity to identify new genetic elements related to complex cognitive functions. Taking advantage of multi-level genomic analysis, here we studied the genetic basis of human short-term (STM, n = 1623) and long-term (LTM, n = 1522) memory functions. Heritability estimation based on single nucleotide polymorphism showed moderate ... Read more >>

Eur. J. Hum. Genet. (European journal of human genetics : EJHG)
[2018, 26(11):1668-1678]

Cited: 1 time

View full text PDF listing >>



Transient ischemic attack characterized by external strabismus of the left eye: A case report.

Xue Wang, Yang Yu, Wenxia Zhang, Hongmei Meng,

Patients rarely display eye movement dysfunctions as the primary symptom in transient ischemic attack.A 58-year-old patient with a history of hypertension and smoking presented with a 1-month history of paroxysmal exotropia of the left eye and double vision. No obvious abnormality was found in imaging examination and the patient ignored ... Read more >>

Medicine (Baltimore) (Medicine)
[2018, 97(24):e11150]

Cited: 0 times

View full text PDF listing >>



Advertisement

Disclaimer
1.1903 s