Full Text Journal Articles by
Author Wendy Harris

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Transitions of Care After Critical Illness-Challenges to Recovery and Adaptive Problem Solving.

Kimberley J Haines, Elizabeth Hibbert, Nina Leggett, Leanne M Boehm, Tarli Hall, Rita N Bakhru, Anthony J Bastin, Brad W Butcher, Tammy L Eaton, Wendy Harris, Aluko A Hope, James Jackson, Annie Johnson, Janet A Kloos, Karen A Korzick, Pamela Mactavish, Joel Meyer, Ashley Montgomery-Yates, Tara Quasim, Andrew Slack, Dorothy Wade, Mary Still, Giora Netzer, Ramona O Hopkins, Theodore J Iwashyna, Mark E Mikkelsen, Joanne McPeake, Carla M Sevin, ,

<h4>Objectives</h4>Investigate the challenges experienced by survivors of critical illness and their caregivers across the transitions of care from intensive care to community, and the potential problem-solving strategies used to navigate these challenges.<h4>Design</h4>Qualitative design-data generation via interviews and data analysis via the framework analysis method.<h4>Setting</h4>Patients and caregivers from three continents, identified ... Read more >>

Crit Care Med (Critical care medicine)
[2021, 49(11):1923-1931]

Cited: 0 times

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Benefits of Peer Support for Intensive Care Unit Survivors: Sharing Experiences, Care Debriefing, and Altruism.

Joanne McPeake, Theodore J Iwashyna, Leanne M Boehm, Elizabeth Hibbert, Rita N Bakhru, Anthony J Bastin, Brad W Butcher, Tammy L Eaton, Wendy Harris, Aluko A Hope, James Jackson, Annie Johnson, Janet A Kloos, Karen A Korzick, Joel Meyer, Ashley Montgomery-Yates, Mark E Mikkelsen, Andrew Slack, Dorothy Wade, Mary Still, Giora Netzer, Ramona O Hopkins, Tara Quasim, Carla M Sevin, Kimberley J Haines,

<h4>Background</h4>After critical illness, patients are often left with impairments in physical, social, emotional, and cognitive functioning. Peer support interventions have been implemented internationally to ameliorate these issues.<h4>Objective</h4>To explore what patients believed to be the key mechanisms of effectiveness of peer support programs implemented during critical care recovery.<h4>Methods</h4>In a secondary analysis ... Read more >>

Am J Crit Care (American journal of critical care : an official publication, American Association of Critical-Care Nurses)
[2021, 30(2):145-149]

Cited: 2 times

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Higher Dose Volumes May Be Better for Evaluating Radiation Pneumonitis in Lung Proton Therapy Patients Compared With Traditional Photon-Based Dose Constraints.

Wendy B Harris, Wei Zou, Chingyun Cheng, Varsha Jain, Boon-Keng Kevin Teo, Lei Dong, Steven J Feigenberg, Abigail T Berman, William P Levin, Keith A Cengel, Shannon E O'Reilly,

<h4>Purpose</h4>The dosimetric parameters used clinically to reduce the likelihood of radiation pneumonitis (RP) for lung cancer radiation therapy have traditionally been V20Gy ≤ 30% to 35% and mean lung dose ≤ 20 to 23 Gy; however, these parameters are derived based on studies from photon therapy. The purpose of this ... Read more >>

Adv Radiat Oncol (Advances in radiation oncology)
[2020, 5(5):943-950]

Cited: 0 times

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Key Components of ICU Recovery Programs: What Did Patients Report Provided Benefit?

Joanne McPeake, Leanne M Boehm, Elizabeth Hibbert, Rita N Bakhru, Anthony J Bastin, Brad W Butcher, Tammy L Eaton, Wendy Harris, Aluko A Hope, James Jackson, Annie Johnson, Janet A Kloos, Karen A Korzick, Pamela MacTavish, Joel Meyer, Ashley Montgomery-Yates, Tara Quasim, Andrew Slack, Dorothy Wade, Mary Still, Giora Netzer, Ramona O Hopkins, Mark E Mikkelsen, Theodore J Iwashyna, Kimberley J Haines, Carla M Sevin,

To understand from the perspective of patients who did, and did not attend ICU recovery programs, what were the most important components of successful programs and how should they be organized. Design:International, qualitative study. Setting:Fourteen hospitals in the United States, United Kingdom, and Australia. Patients:We conducted 66 semi-structured interviews with ... Read more >>

Crit Care Explor (Critical care explorations)
[2020, 2(4):e0088]

Cited: 7 times

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Volumetric cine magnetic resonance imaging (VC-MRI) using motion modeling, free-form deformation and multi-slice undersampled 2D cine MRI reconstructed with spatio-temporal low-rank decomposition.

Wendy Harris, Fang-Fang Yin, Jing Cai, Lei Ren,

Background:The purpose of this study is to improve on-board volumetric cine magnetic resonance imaging (VC-MRI) using multi-slice undersampled cine images reconstructed using spatio-temporal k-space data, patient prior 4D-MRI, motion modeling (MM) and free-form deformation (FD) for real-time 3D target verification of liver and lung radiotherapy. Methods:A previous method was developed ... Read more >>

Quant Imaging Med Surg (Quantitative imaging in medicine and surgery)
[2020, 10(2):432-450]

Cited: 0 times

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Predicting real-time 3D deformation field maps (DFM) based on volumetric cine MRI (VC-MRI) and artificial neural networks for on-board 4D target tracking: a feasibility study.

Jonathan Pham, Wendy Harris, Wenzheng Sun, Zi Yang, Fang-Fang Yin, Lei Ren,

To predict real-time 3D deformation field maps (DFMs) using Volumetric Cine MRI (VC-MRI) and adaptive boosting and multi-layer perceptron neural network (ADMLP-NN) for 4D target tracking. One phase of a prior 4D-MRI is set as the prior phase, MRI<sub>prior</sub>. Principal component analysis (PCA) is used to extract three major respiratory ... Read more >>

Phys Med Biol (Physics in medicine and biology)
[2019, 64(16):165016]

Cited: 2 times

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Models of Peer Support to Remediate Post-Intensive Care Syndrome: A Report Developed by the Society of Critical Care Medicine Thrive International Peer Support Collaborative.

Joanne McPeake, Eliotte L Hirshberg, Leeann M Christie, Kelly Drumright, Kimberley Haines, Catherine L Hough, Joel Meyer, Dorothy Wade, Adair Andrews, Rita Bakhru, Samantha Bates, John A Barwise, Julie Bastarache, Sarah J Beesley, Leanne M Boehm, Sheryl Brown, Alison S Clay, Penelope Firshman, Steven Greenberg, Wendy Harris, Christopher Hill, Carol Hodgson, Clare Holdsworth, Aluko A Hope, Ramona O Hopkins, David C J Howell, Anna Janssen, James C Jackson, Annie Johnson, Erin K Kross, Daniela Lamas, Belinda MacLeod-Smith, Ruth Mandel, John Marshall, Mark E Mikkelsen, Megan Nackino, Tara Quasim, Carla M Sevin, Andrew Slack, Rachel Spurr, Mary Still, Carol Thompson, Gerald Weinhouse, M Elizabeth Wilcox, Theodore J Iwashyna,

<h4>Objectives</h4>Patients and caregivers can experience a range of physical, psychologic, and cognitive problems following critical care discharge. The use of peer support has been proposed as an innovative support mechanism.<h4>Design</h4>We sought to identify technical, safety, and procedural aspects of existing operational models of peer support, among the Society of Critical ... Read more >>

Crit Care Med (Critical care medicine)
[2019, 47(1):e21-e27]

Cited: 15 times

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Markerless Four-Dimensional-Cone Beam Computed Tomography Projection-Phase Sorting Using Prior Knowledge and Patient Motion Modeling: A Feasibility Study.

Lei Zhang, Yawei Zhang, You Zhang, Wendy B Harris, Fang-Fang Yin, Jing Cai, Lei Ren,

Aim:During cancer radiotherapy treatment, on-board four-dimensional-cone beam computed tomography (4D-CBCT) provides important patient 4D volumetric information for tumor target verification. Reconstruction of 4D-CBCT images requires sorting of acquired projections into different respiratory phases. Traditional phase sorting methods are either based on external surrogates, which might miscorrelate with internal structures; or ... Read more >>

Cancer Transl Med (Cancer translational medicine)
[2017, 3(6):185-193]

Cited: 0 times

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Accelerating volumetric cine MRI (VC-MRI) using undersampling for real-time 3D target localization/tracking in radiation therapy: a feasibility study.

Wendy Harris, Fang-Fang Yin, Chunhao Wang, You Zhang, Jing Cai, Lei Ren,

PURPOSE:To accelerate volumetric cine MRI (VC-MRI) using undersampled 2D-cine MRI to provide real-time 3D guidance for gating/target tracking in radiotherapy. METHODS:4D-MRI is acquired during patient simulation. One phase of the prior 4D-MRI is selected as the prior images, designated as MRIprior. The on-board VC-MRI at each time-step is considered a ... Read more >>

Phys Med Biol (Physics in medicine and biology)
[2017, 63(1):01NT01]

Cited: 5 times

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Estimating 4D-CBCT from prior information and extremely limited angle projections using structural PCA and weighted free-form deformation for lung radiotherapy.

Wendy Harris, You Zhang, Fang-Fang Yin, Lei Ren,

<h4>Purpose</h4>To investigate the feasibility of using structural-based principal component analysis (PCA) motion-modeling and weighted free-form deformation to estimate on-board 4D-CBCT using prior information and extremely limited angle projections for potential 4D target verification of lung radiotherapy.<h4>Methods</h4>A technique for lung 4D-CBCT reconstruction has been previously developed using a deformation field map ... Read more >>

Med Phys (Medical physics)
[2017, 44(3):1089-1104]

Cited: 10 times

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A Technique for Generating Volumetric Cine-Magnetic Resonance Imaging.

Wendy Harris, Lei Ren, Jing Cai, You Zhang, Zheng Chang, Fang-Fang Yin,

<h4>Purpose</h4>The purpose of this study was to develop a techique to generate on-board volumetric cine-magnetic resonance imaging (VC-MRI) using patient prior images, motion modeling, and on-board 2-dimensional cine MRI.<h4>Methods and materials</h4>One phase of a 4-dimensional MRI acquired during patient simulation is used as patient prior images. Three major respiratory deformation ... Read more >>

Int J Radiat Oncol Biol Phys (International journal of radiation oncology, biology, physics)
[2016, 95(2):844-853]

Cited: 22 times

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Taking care: practice and philosophy of communication in a critical care follow-up clinic.

Anthony Hazzard, Wendy Harris, David Howell,

Human consciousness is inextricable from communication. The conditions of communication in the clinical context are defined by the caring intention and the unequal relationship, which imply special responsibilities on the part of the clinician. The conventional hermeneutic model of communication proposes a close examination of the context of the other, ... Read more >>

Intensive Crit Care Nurs (Intensive & critical care nursing)
[2013, 29(3):158-165]

Cited: 2 times

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Does discordancy between the CD4 count and CD4 percentage in HIV-positive individuals influence outcomes on highly active antiretroviral therapy?

Mark Gompels, David T Dunn, Andrew Phillips, Debbie Dooley, Andrew De Burgh Thomas, Jane Anderson, Frank Post, Deenan Pillay, Brian Gazzard, Teresa Hill, Margaret Johnson, Richard Gilson, Loveleen Bansi, Philippa Easterbrook, Martin Fisher, John Walsh, Chloe Orkin, Jonathan Ainsworth, Clifford Leen, Caroline Sabin, ,

<h4>Introduction</h4>The CD4 count and CD4 percentage (CD4%) are both strong predictors of clinical disease progression in human immunodeficiency virus (HIV). Although individuals may show discordancy between their CD4 count and CD4%, the clinical relevance of this is unclear.<h4>Methods</h4>Discordancy was defined where the CD4% was ≤10th percentile for a selected CD4 ... Read more >>

J Infect Dis (The Journal of infectious diseases)
[2012, 205(4):540-547]

Cited: 3 times

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Data linkage reduces loss to follow-up in an observational HIV cohort study.

Teresa Hill, Loveleen Bansi, Caroline Sabin, Andrew Phillips, David Dunn, Jane Anderson, Philippa Easterbrook, Martin Fisher, Brian Gazzard, Richard Gilson, Margaret Johnson, Clifford Leen, Chloe Orkin, Achim Schwenk, John Walsh, Alan Winston, Abdel Babiker, Valerie Delpech, ,

<h4>Objective</h4>To ascertain the degree of loss to follow-up in a cohort and to identify its predictors.<h4>Study design and setting</h4>Human immunodeficiency virus (HIV)-infected individuals without CD4 cell counts for a year or more were defined as potentially lost to follow-up (LFU). Multivariable Poisson regression models identified the risk factors for potential ... Read more >>

J Clin Epidemiol (Journal of clinical epidemiology)
[2010, 63(10):1101-1109]

Cited: 15 times

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Factors influencing lopinavir and atazanavir plasma concentration.

Wolfgang Stöhr, David Back, David Dunn, Caroline Sabin, Alan Winston, Richard Gilson, Deenan Pillay, Teresa Hill, Jonathan Ainsworth, Brian Gazzard, Clifford Leen, Loveleen Bansi, Martin Fisher, Chloe Orkin, Jane Anderson, Margaret Johnson, Philippa Easterbrook, Sara Gibbons, Saye Khoo, ,

<h4>Background</h4>The protease inhibitors lopinavir and atazanavir are both recommended for treatment of HIV-infected patients. Considerable inter-individual variability in plasma concentration has been observed for both drugs. The aim of this study was to evaluate which demographic factors and concomitant drugs are associated with lopinavir and atazanavir plasma concentration.<h4>Methods</h4>Data from the ... Read more >>

J Antimicrob Chemother (The Journal of antimicrobial chemotherapy)
[2010, 65(1):129-137]

Cited: 10 times

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Discordant responses on starting highly active antiretroviral therapy: suboptimal CD4 increases despite early viral suppression in the UK Collaborative HIV Cohort (UK CHIC) Study.

R J C Gilson, S-L Man, A Copas, A Rider, S Forsyth, T Hill, L Bansi, K Porter, B Gazzard, C Orkin, D Pillay, A Schwenk, M Johnson, P Easterbook, J Walsh, M Fisher, C Leen, J Anderson, C A Sabin, ,

<h4>Objectives</h4>Patients starting highly active antiretroviral therapy (HAART) may have a suboptimal CD4 increase despite rapid virological suppression. The frequency and the significance for patient care of this discordant response are uncertain. This study was designed to determine the incidence of a discordant response at two time-points, soon after 6 months ... Read more >>

HIV Med (HIV medicine)
[2010, 11(2):152-160]

Cited: 26 times

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Risk factors for treatment-limiting toxicities in patients starting nevirapine-containing antiretroviral therapy.

Anouk M Kesselring, Ferdinand W Wit, Caroline A Sabin, Jens D Lundgren, M John Gill, Jose M Gatell, Andri Rauch, Julio S Montaner, Frank de Wolf, Peter Reiss, Amanda Mocroft, ,

<h4>Background</h4>This collaboration of seven observational clinical cohorts investigated risk factors for treatment-limiting toxicities in both antiretroviral-naive and experienced patients starting nevirapine-based combination antiretroviral therapy (NVPc).<h4>Methods</h4>Patients starting NVPc after 1 January 1998 were included. CD4 cell count at starting NVPc was classified as high (>400/microl/>250/microl for men/women, respectively) or low. Cox ... Read more >>

AIDS (AIDS (London, England))
[2009, 23(13):1689-1699]

Cited: 44 times

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The associations between age and the development of laboratory abnormalities and treatment discontinuation for reasons other than virological failure in the first year of highly active antiretroviral therapy.

C A Sabin, C J Smith, V Delpech, J Anderson, L Bansi, R Gilson, A Schwenk, C Leen, B Gazzard, K Porter, N Mackie, M Fisher, C Orkin, M Johnson, P Easterbrook, T Hill, A N Phillips, ,

<h4>Objective</h4>The aim of this study was to describe the relationship between age and the time to treatment discontinuation in the absence of virological failure as well as the development of specific laboratory abnormalities, in patients starting highly active antiretroviral therapy (HAART) for the first time.<h4>Methods</h4>Analyses included 8708 antiretroviral-naïve patients from ... Read more >>

HIV Med (HIV medicine)
[2009, 10(1):35-43]

Cited: 18 times

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Playing the game on the World Wide Web.

Linden Rhodes, Fiona Duignan, Wendy Harris,

<h4>Issue addressed</h4>'Celebrate - do it Safely' is a project aimed at reducing youth alcohol-related harm on the Central Coast, New South Wales (NSW). The primary focus for 2003 was to use the world wide web and the website www.celebratesafely.com.au to raise awareness and reinforce the message of how to party ... Read more >>

Health Promot J Austr (Health promotion journal of Australia : official journal of Australian Association of Health Promotion Professionals)
[2006, 17(1):27-31]

Cited: 0 times

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Bottleshops and 'ready-to-drink' alcoholic beverages.

Anthony Smith, Christine Edwards, Wendy Harris,

<h4>Issue addressed</h4>To assess whether the strategies used to sell the 'ready-to-drink' (RTD) category of alcoholic beverages is contributing to alcohol-related harm among adolescents.<h4>Methods</h4>An initial investigation of bottleshops, which included an observational study designed to analyse methods employed by the liquor industry to market RTDs in bottleshops, on the central coast ... Read more >>

Health Promot J Austr (Health promotion journal of Australia : official journal of Australian Association of Health Promotion Professionals)
[2005, 16(1):32-36]

Cited: 2 times

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Methotrexate-associated medication errors.

Wendy Harris,

Am J Health Syst Pharm (American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists)
[2004, 61(24):2635]

Cited: 3 times

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Characterization of a neurovirulent aciclovir-resistant variant of herpes simplex virus.

Finn Grey, Mike Sowa, Peter Collins, Rob J Fenton, Wendy Harris, Wendy Snowden, Stacey Efstathiou, Graham Darby,

A clinical isolate of herpes simplex virus type 1 that is aciclovir resistant but neurovirulent in mice was described previously. The mutation in this virus is a double G insertion in a run of seven G residues that has been shown previously to be a mutational hotspot. Using a sensitive ... Read more >>

J Gen Virol (The Journal of general virology)
[2003, 84(Pt 6):1403-1410]

Cited: 15 times

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Emergence of resistance to protease inhibitor amprenavir in human immunodeficiency virus type 1-infected patients: selection of four alternative viral protease genotypes and influence of viral susceptibility to coadministered reverse transcriptase nucleoside inhibitors.

Michael Maguire, Denise Shortino, Astrid Klein, Wendy Harris, Varsha Manohitharajah, Margaret Tisdale, Robert Elston, Jane Yeo, Sharon Randall, Fan Xu, Hayley Parker, Jackie May, Wendy Snowden,

Previous data have indicated that the development of resistance to amprenavir, an inhibitor of the human immunodeficiency virus type 1 protease, is associated with the substitution of valine for isoleucine at residue 50 (I50V) in the viral protease. We present further findings from retrospective genotypic and phenotypic analyses of plasma ... Read more >>

Antimicrob Agents Chemother (Antimicrobial agents and chemotherapy)
[2002, 46(3):731-738]

Cited: 51 times

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Phenotypic and genotypic characterization of clinical isolates of herpes simplex virus resistant to aciclovir.

Wendy Harris, Peter Collins, Rob J Fenton, Wendy Snowden, Mike Sowa, Graham Darby,

A panel of 10 clinical isolates of herpes simplex virus (HSV) deficient in the expression of thymidine kinase (TK) and phenotypically resistant to aciclovir was characterized. Sequence analysis revealed a variety of mutations in TK (nucleotide substitutions, insertions and deletions), most of which resulted in truncated TK polypeptides. In line ... Read more >>

J Gen Virol (The Journal of general virology)
[2003, 84(Pt 6):1393-1401]

Cited: 23 times

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