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Author Weihua Sun

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Dexmedetomidine for prevention of propofol injection pain upon induction of anesthesia: a meta-analysis.

Liting Ji, Weihua Sun, Yunping Lan, Changxing Xia, Gongmin Yu, Qinghua Wu, Shufen Yang, Xiaofeng Xu,

PURPOSE:Propofol injection pain is a very common problem during the induction of general anesthesia. The purpose of this review is to evaluate the effectiveness of dexmedetomidine for the prevention of propofol injection pain so as to provide evidence for future clinical applications. METHODS:PubMed, Embase, Cochrane library, and Google Scholar databases ... Read more >>

Eur. J. Clin. Pharmacol. (European journal of clinical pharmacology)
[2020, :]

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Ubiquitin-Fold Modifier-1 Participates in the Diabetic Inflammatory Response by Regulating NF-κB p65 Nuclear Translocation and the Ubiquitination and Degradation of IκBα.

Xiaolei Hu, Hengyan Zhang, Langen Zhuang, Guoxi Jin, Qingqing Yang, Min Li, Weihua Sun, Fengling Chen,

Background:Ubiquitin-fold modifier-1 (Ufm1) is a recently identified ubiquitin-like protein. We previously confirmed that Ufm1 expression was increased in diabetic mice. However, its role in the development of diabetes remains undefined. Methods:Lentivirus-mediated gene knockdown and overexpression techniques were used to observe the effect of Ufm1 on the expression of inflammatory factors, ... Read more >>

Drug Des Devel Ther (Drug design, development and therapy)
[2020, 14:795-810]

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Soluble ST2 is associated with increased carotid intima-media thickness in patients with type 2 diabetes mellitus: A case-control study.

Xiaolei Hu, Hengyan Zhang, Yuan Song, Qingqing Yang, Langen Zhuang, Guoxi Jin, Shirong Zhang, Weihua Sun, Zhaoming Shi,

Soluble suppression of tumorigenicity 2 (sST2) is a free form of membrane-bound ST2, which is a member of the interleukin-1 receptor family. Previous research has shown that sST2 is associated with diabetes, but cardiovascular risk factors have not been established.To analyze the relationship between sST2 and carotid intima-media thickness (CIMT) ... Read more >>

Medicine (Baltimore) (Medicine)
[2020, 99(5):e18940]

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Correlation of TSHR and CTLA-4 Single Nucleotide Polymorphisms with Graves Disease.

Weihua Sun, Xiaomei Zhang, Jing Wu, Wendi Zhao, Shuangxia Zhao, Minglong Li,

This study was designed to explore the association between Graves disease (GD) and thyroid-stimulating hormone receptor (TSHR) and cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) single nucleotide polymorphisms (SNPs). We studied a total of 1217 subjects from a Han population in northern Anhui province in China. Six SNPs within TSHR (rs179247, rs12101261, ... Read more >>

Int J Genomics (International journal of genomics)
[2019, 2019:6982623]

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Horner syndrome as a postoperative complication after minimally invasive video-assisted thyroidectomy: A case report.

Xiaolei Hu, Xiaomei Zhang, Huaiyong Gan, Dajun Yu, Weihua Sun, Zhaoming Shi,

Horner syndrome is an unusual complication after thyroidectomy.We report a case of Horner syndrome in a 34-year-old female patient with Graves disease associated with papillary thyroid carcinoma who underwent left-side minimally invasive video-assisted thyroidectomy and neck dissection.Horner syndrome was diagnosed based on left myosis, eyelid ptosis, and mild enophthalmos, which ... Read more >>

Medicine (Baltimore) (Medicine)
[2017, 96(48):e8888]

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A New Chinese Medicine Intestine Formula Greatly Improves the Effect of Aminosalicylate on Ulcerative Colitis.

Baohai Liu, Xuehua Piao, Lianyi Guo, Guijun Wang, Weihua Sun, Leming Gao, Xuefeng Zheng, Yanli Fang,

Ulcerative colitis (UC) is a chronic lifelong inflammatory disorder of the colon. Current medical treatment of UC relies predominantly on the use of traditional drugs, including aminosalicylates, corticosteroids, and immunosuppressants, which failed to effectively control this disease's progression and produced various side effects. Here, we report a new Chinese medicine ... Read more >>

Evid Based Complement Alternat Med (Evidence-based complementary and alternative medicine : eCAM)
[2017, 2017:7323129]

Cited: 3 times

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Competition for electrons between pyridine and quinoline during their simultaneous biodegradation.

Hua Xu, Weihua Sun, Ning Yan, Danni Li, Xueqi Wang, Tingting Yu, Yongming Zhang, Bruce E Rittmann,

Biodegradation of pyridine and quinoline is initiated with mono-oxygenation reactions that require an intracellular electron donor. Simultaneous biodegradation of both substrates should set up competition for the intracellular electron donor that may inhibit one or more of the mono-oxygenation steps. An internal circulation baffled biofilm reactor (ICBBR) was used to ... Read more >>

Environ Sci Pollut Res Int (Environmental science and pollution research international)
[2017, 24(32):25082-25091]

Cited: 1 time

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Activation of phosphatidylinositol 3-kinase/AKT/snail signaling pathway contributes to epithelial-mesenchymal transition-induced multi-drug resistance to sorafenib in hepatocellular carcinoma cells.

Jiejie Dong, Bo Zhai, Weihua Sun, Fengli Hu, Hao Cheng, Jun Xu,

Sorafenib, an orally available kinase inhibitor, is the standard first-line systemic drug for advanced hepatocellular carcinoma (HCC), and it exerts potent inhibitory activity against epithelial-mesenchymal transition (EMT) and multidrug resistance (MDR) by inhibiting mitogen-activated protein kinase (MAPK) signaling in HCC. However, after long-term exposure to sorafenib, HCC cells exhibit EMT ... Read more >>

PLoS ONE (PloS one)
[2017, 12(9):e0185088]

Cited: 17 times

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Coupling-based Huygens' meta-atom utilizing bilayer complementary plasmonic structure for light manipulation.

Tongjun Liu, Lirong Huang, Wei Hong, Yonghong Ling, Jing Luan, Yali Sun, Weihua Sun,

Huygens' meta-atom is the basic building unit of Huygens' metasurfaces allowing for almost arbitrary wavefront shaping across a surface. We here present a kind of Huygens' meta-atom by coupling a nanodisk to its Babinet-complementary structure (nanohole), and develop an optical lumped nanocircuit model to analyze vertical and lateral coupling effects ... Read more >>

Opt Express (Optics express)
[2017, 25(14):16332-16346]

Cited: 3 times

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First reported Chinese case of guanidinoacetate methyltransferase deficiency in a 4-year-old child.

Weihua Sun, Yi Wang, Zhen Zu, Yi Jiang, Wei Lu, Huijun Wang, Bingbing Wu, Ping Zhang, Xiaomin Peng, Hao Zhou,

Guanidinoacetate methyltransferase (GAMT) deficiency is a rare inherited disorder characterized by creatine (Cr) depletion and guanidinoacetate (GAA) accumulation in body fluids. We report the first identified Chinese case, diagnosed in a 4-year-old girl with onset of global developmental. Low Cr and high GAA levels were detected in her serum and ... Read more >>

Clin. Chim. Acta (Clinica chimica acta; international journal of clinical chemistry)
[2017, 470:42-45]

Cited: 0 times

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Simultaneous di-oxygenation and denitrification in an internal circulation baffled bioreactor.

Ling Jiang, Yingxia Tang, Weihua Sun, Na Yi, Yongming Zhang, Hanchang Shi, Bruce E Rittmann,

An internal circulation baffled bioreactor was employed to realize simultaneous di-oxygenation of phthalic acid (PA) and denitrification of nitrate, which require aerobic and anoxic conditions, respectively. Adding a small concentration of succinate as an exogenous electron donor stimulated PA di-oxygenation, which produced readily oxidizable downstream products whose oxidation also enhanced ... Read more >>

Biodegradation (Biodegradation)
[2017, 28(2-3):195-203]

Cited: 1 time

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Accelerating biodegradation of a monoazo dye Acid Orange 7 by using its endogenous electron donors.

Weihua Sun, Chengji Zhang, Jun Chen, Bingbing Zhang, Hongzhuan Zhang, Yongming Zhang, Lujun Chen,

Biodegradation of a monoazo dye - Acid Orange 7 (AO7) was investigated by using an internal circulation baffled biofilm reactor. For accelerating AO7 biodegradation, endogenous electron donors produced from AO7 by UV photolysis were added into the reactor. The result shows that AO7 removal rate can be accelerated by using ... Read more >>

J. Hazard. Mater. (Journal of hazardous materials)
[2017, 324(Pt B):739-743]

Cited: 1 time

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Geniposide reduces development of streptozotocin-induced diabetic nephropathy via regulating nuclear factor-kappa B signaling pathways.

Xiaolei Hu, Xiaomei Zhang, Guoxi Jin, Zhaoming Shi, Weihua Sun, Fengling Chen,

Renal pathology was a commonly seen complication in patients with diabetes. Geniposide (GPO) was previously demonstrated to modulate glucose metabolism in diabetes. This study was to investigate effects of GPO in streptozotocin-induced diabetic rats and its underlying mechanism. Renal function in diabetic rats was evaluated by levels of serum creatinine ... Read more >>

Fundam Clin Pharmacol (Fundamental & clinical pharmacology)
[2017, 31(1):54-63]

Cited: 7 times

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Coupled electron beam radiation and MBR treatment of textile wastewater containing polyvinyl alcohol.

Weihua Sun, Jun Chen, Lujun Chen, Jianlong Wang, Yongming Zhang,

Advanced oxidation processes (AOP) can be combined with biological treatments for recalcitrant organic pollutant decomposition. However, there has been no thorough investigation on the coupling of AOPs and membrane bioreactors (MBR) to treat polymer organic pollutants. This study proposes a new AOP that couples electron beam (EB) radiation and MBR ... Read more >>

Chemosphere (Chemosphere)
[2016, 155:57-61]

Cited: 1 time

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Inactivation of the Progesterone Receptor in Mx1+ Cells Potentiates Osteogenesis in Calvaria but Not in Long Bone.

Zhendong A Zhong, Weihua Sun, Haiyan Chen, Hongliang Zhang, Nancy E Lane, Wei Yao,

The effect of progesterone on bone remains elusive. We previously reported that global progesterone receptor (PR) knockout mice displayed high bone mass phenotype, suggesting that PR influences bone growth and modeling. Recently, Mx1+ cells were characterized to be mesenchymal stem cell-like pluripotent Cells. The aim of this study was to ... Read more >>

PLoS ONE (PloS one)
[2015, 10(10):e0139490]

Cited: 4 times

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[Identification of ustiloxins in false smut balls of rice based on high performance liquid chromatography-high resolution mass spectrometry].

Yingfang Bian, Shasha Yu, Renxiang Mou, Zhaoyun Cao, Weihua Sun, Huan Yang, Xiaoyan Lin, Mingxue Chen,

A sensitive method was developed for the simultaneous identification of five ustiloxins in the false smut balls of rice by high performance liquid chromatography-linear ion trap/orbitrap high resolution mass spectrometry (HPLC-LTQ/Orbitrap MS). The samples were extracted with deionized water under ultrasonic condition for 10 min, then purified by a strong ... Read more >>

Se Pu (Se pu = Chinese journal of chromatography)
[2015, 33(10):1046-1050]

Cited: 1 time

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Optimizing tamoxifen-inducible Cre/loxp system to reduce tamoxifen effect on bone turnover in long bones of young mice.

Zhendong A Zhong, Weihua Sun, Haiyan Chen, Hongliang Zhang, Yu-An E Lay, Nancy E Lane, Wei Yao,

For tamoxifen-dependent Cre recombinase, also known as CreER recombinase, tamoxifen (TAM) is used to activate the Cre to generate time- and tissue-specific mouse mutants. TAM is a potent CreER system inducer; however, TAM is also an active selective estrogen receptor modulator (SERM) that can influence bone homeostasis. The purpose of ... Read more >>

Bone (Bone)
[2015, 81:614-619]

Cited: 13 times

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Synergistic effect of ozonation and ionizing radiation for PVA decomposition.

Weihua Sun, Lujun Chen, Yongming Zhang, Jianlong Wang,

Ozonation and ionizing radiation are both advanced oxidation processes (AOPs) without chemical addition and secondary pollution. Also, the two processes' efficiency is determined by different pH conditions, which creates more possibilities for their combination. Importantly, the combined process of ozonation and ionizing radiation could be suitable for treating wastewaters with ... Read more >>

J Environ Sci (China) (Journal of environmental sciences (China))
[2015, 34:63-67]

Cited: 3 times

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Factors associated with the age of natural menopause and menopausal symptoms in Chinese women.

Lin Li, Jie Wu, Danhua Pu, Yang Zhao, Chunhua Wan, Lihua Sun, Cai-e Shen, Weihua Sun, Zhimin Yuan, Qin Shen, Xiaoyan He, Jian Jiang, Naimei Luo, Ya He, Qiuju Qian, Peiqin Cai, Mei Zhang,

OBJECTIVE: To investigate the factors associated with the age of natural menopause and menopausal symptoms in a large population of Chinese middle-aged women. STUDY DESIGN: In this cross-sectional study, a total of 20,275 women (40-65 years) attending health screening in Jiangsu Province of China were enrolled. A structured questionnaire was ... Read more >>

Maturitas (Maturitas)
[2012, 73(4):354-360]

Cited: 41 times

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Improvement of biodegradability of PVA-containing wastewater by ionizing radiation pretreatment.

Weihua Sun, Jinping Tian, Lujun Chen, Shijun He, Jianlong Wang,

Polyvinyl alcohol (PVA) has been widely used as sizing agents in textile and manufacturing industry, and it is a refractory compound with low biodegradability.The objective of this paper was to treat the PVA-containing wastewater using gamma irradiation as a pretreatment strategy to improve its biodegradability and to determine the roles ... Read more >>

Environ Sci Pollut Res Int (Environmental science and pollution research international)
[2012, 19(8):3178-3184]

Cited: 5 times

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The screening of inborn errors of metabolism in sick Chinese infants by tandem mass spectrometry and gas chromatography/mass spectrometry.

Weihua Sun, Yi Wang, Yi Yang, Jianshe Wang, Yun Cao, Feihong Luo, Wei Lu, Yongmei Peng, Haili Yao, Penglin Qiu,

BACKGROUND: Analyses of amino acid/acylcarnitines in dried blood spots (DBS) and organic acids in urine are the primary tests for inborn errors of metabolism (IEMs). Automated tandem mass spectrometry (MS/MS) and gas chromatography/mass spectrometry (GC/MS) can rapidly and simultaneously detect numerous metabolic compounds with high precision and sensitivity. METHODS: Three ... Read more >>

Clin. Chim. Acta (Clinica chimica acta; international journal of clinical chemistry)
[2011, 412(13-14):1270-1274]

Cited: 12 times

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Intertill subsoiling-protecting device

CHUANYOU ZHOU, WEIHUA SUN, GUOJUN JIANG, KEMING CAI, HONGBO YU, JIAHONG WU,

An intertillage and deep loosening seeding protecting device belongs to a agricultural machinery a clockwise beam is fixedly provided with a seeding protecting tooth carrier, two sides of the seeding protecting tooth carrier are matched and provided with elastic seeding protecting rulers that are positioned at the left side and ... Read more >>

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Preparation method of CO selective methanation catalyst

GANG XIAO, WEIHUA SUN, SHUAILIN ZHOU,

The invention discloses a preparation method of a CO selective methanation catalyst, in particular to a preparation method of a CO selective methanation catalyst using nanometer cerium-zirconium composite oxide as a carrier, which comprises the following steps: dissolving the nitrates of Ce and Zr into water keeping the pH value ... Read more >>

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[Screening and analysis of early cardiopathology-related gene in type 2 diabetes mellitus].

Fanglin Zhang, Guo Li, Wei Ding, Youping Liu, Chao Xie, Di Zhang, Wenzhong Zhou, Weihua Sun, Jialin Yang, Min Luo,

OBJECTIVE: To screen and analyze early cardiopathology related gene in type 2 diabetes mellitus (DM). METHODS: (1) To develop a rat model of type 2 DM, SD rats were injected with streptozotocin (STZ, 15 mg/kg) after high caloric diet had been given for two months. (2) After establishment of the ... Read more >>

Zhonghua Nei Ke Za Zhi (Zhonghua nei ke za zhi)
[2002, 41(8):530-533]

Cited: 2 times

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