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Author Wei Ying Lu


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The gut microbiota confers the glucose-and lipid-lowering effect of Laurolitsine in db/db mice

Rui-qi Wang, Fang Zhang, Ya-nan Yang, Yin-feng Tan, Yong Zhang, Lin Dong, Ning Ma, Wei-ying Lu, Chong-ming Wu, Xiao-po Zhang,

<h4>Background: </h4> Modulations on gut microbiota by traditional Chinese medicines (TCMs) and their active components are emerging as potential therapeutic agents on diabetes. Litsea glutinosa is a TCM used in clinic to treat diabetes with alkaloids as the active constituents, and the Laurolitsine is the richest one. Purpose Based ... Read more >>

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Successful surgical sperm retrieval from a patient with 45,X/46,XY mosaicism followed by in vitro fertilization pregnancy: A case report.

Yu Zhang, Zheng Liu, Jian Ou, Ling-Xiao Zhang, Wei-Ying Lu, Qi Li, Yanlin Ma,

<h4>Rationale</h4>Mixed gonadal dysgenesis is a rare disorder of sex development, and typically contains a mosaic 45,X/46,XY karyotype.<h4>Patient concerns</h4>We reported here a case of a 42-year-old man with infertility for 6 years and inability to ejaculate during intercourse.<h4>Diagnosis</h4>Physical examination confirmed that the external genitalia was male. The right testis of this ... Read more >>

Medicine (Baltimore) (Medicine)
[2020, 99(40):e22223]

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LAPTM5 is transactivated by RUNX2 and involved in RANKL trafficking in osteoblastic cells.

Yuan-Ming Geng, Cheng-Xia Liu, Wei-Ying Lu, Ping Liu, Pei-Yan Yuan, Wei-Long Liu, Ping-Ping Xu, Xiao-Qing Shen,

The present study aimed to investigate the role of lysosomal‑associated transmembrane protein 5 (LAPTM5) in osteoclast differentiation induced by osteoblasts. The results demonstrated that the expression levels of LAPTM5 were downregulated following runt‑related transcription factor 2 (RUNX2) silencing and upregulated following RUNX2 overexpression in ST2 cells. Chromatin immunoprecipitation analysis identified the binding ... Read more >>

Mol Med Rep (Molecular medicine reports)
[2019, 20(5):4193-4201]

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Effects of high glucose on expression of OPG and RANKL in rat aortic vascular smooth muscle cells.

Hong-Juan Chang, Tian-Fa Li, Jun-Li Guo, You-Ling Lan, Yue-Qiong Kong, Xin Meng, Xian-Ji Ma, Xiao-Ling Lu, Wei-Ying Lu, Shao-Jiang Zheng,

<h4>Objective</h4>To explore effect of high glucose on expression of osteoprotegerin (OPG) and receptor activator of NF- κ B ligand (RANKE) in rat aortic vascular smooth muscle cells.<h4>Methods</h4>SD rats were intraperitoneally injected with streptozotocin, OPG and RANKL expression in rat thoracic aortas were detected by immunohistochemical staining. In cultured vascular smooth ... Read more >>

Asian Pac J Trop Med (Asian Pacific journal of tropical medicine)
[2015, 8(3):209-213]

Cited: 3 times

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A whole-mechanical method to establish human embryonic stem cell line HN4 from discarded embryos.

Bin Li, Lan Xu, Wei-Ying Lu, Wen Xu, Mei-Hong Wang, Ke Yang, Juan Dong, Xiao-Yan Ding, Yuan-Hua Huang,

Since the first human embryonic stem cell (hESC) line was generated by Thomson et al. (in Science 282:1145-1147, 1998), hundreds of hESC lines have been reported by different labs, providing resources for basic research and regenerative medicine as well. However it has been widely recognized that hESC lines varied on ... Read more >>

Cytotechnology (Cytotechnology)
[2010, 62(6):509-518]

Cited: 8 times

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