Full Text Journal Articles by
Author Wei Ni

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Magnesium oxide anchored into a hollow carbon sphere realizes synergistic adsorption and activation of CO2 for electrochemical reduction.

Congxin Li, Wei Ni, Xiaogang Zang, Huaizhi Wang, Yixiang Zhou, Zhiyu Yang, Yi-Ming Yan,

We report the synergistic adsorption and activation of CO2 by using magnesium oxide anchored into a hollow carbon sphere (MgO/HCS) as an efficient catalyst for electrochemical reduction of CO2 (ERC). The MgO/HCS catalyst exhibits a high selectivity for CO production with a faradaic efficiency of 81.7% at -1.0 V vs. ... Read more >>

Chem. Commun. (Camb.) (Chemical communications (Cambridge, England))
[2020, 56(45):6062-6065]

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Neural Stem Cell-Conditioned Medium Inhibits Inflammation in Macrophages via Sirt-1 Signaling Pathway in Vitro and Promotes Sciatic Nerve Injury Recovery.

Tianyan Chen, Yilei Li, Wei Ni, Bin Tang, Yusheng Wei, Jing Li, Jiahong Yu, Lei Zhang, Jianyi Gao, Jiqin Zhou, Weining Zhang, Hong Xu, Jiabo Hu,

Chronic persistent inflammation is thought to impede axon regeneration and cause demyelinating disease also with neuropathic pain, leading to more severe dysfunction following peripheral nerve injury. Increasing evidences indicate that neural stem cells have immunomodulatory effects, and previous studies have shown that many of the beneficial effects attributed to stem ... Read more >>

Stem Cells Dev. (Stem cells and development)
[2020, :]

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Association between ceramides and coronary artery stenosis in patients with coronary artery disease.

Chenchen Tu, Lan Xie, Zhenjie Wang, Lili Zhang, Hongmei Wu, Wei Ni, Caixia Li, Lin Li, Yong Zeng,

BACKGROUND:Coronary artery stenosis induces heart diseases including acute coronary syndrome (ACS). Some studies reported the ceramide species are associated with the ACS and major adverse cardia and cerebrovascular events (MACE). However, few studies investigated the association between plasma ceramide levels and the severity of stenosis, together with the onset of ... Read more >>

Lipids Health Dis (Lipids in Health and Disease)
[2020, 19(1):151]

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Paris Saponin VII Induces Apoptosis and Cell Cycle Arrest in Erythroleukemia Cells by a Mitochondrial Membrane Signaling Pathway.

Xin Lin, Babu Gajendran, Krishnapriya M Varier, Wuling Liu, Jingrui Song, Qing Rao, Chunlin Wang, Jianfei Qiu, Wei Ni, XuJie Qin, Min Wen, Haiyang Liu, Yanmei Li,

BACKGROUND AND PURPOSE:Leukemia considered a top-listed ailment, according to WHO, which contributes to the death of a major population of the world every year. Paris Saponin VII (PS), a saponin which was isolated from the roots of Trillium kamtschaticum, from our group, was reported to provide hemostatic, cytotoxic and antimicrobial ... Read more >>

Anticancer Agents Med Chem (Anti-cancer agents in medicinal chemistry)
[2020, :]

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HSPA1A Protects Cells from Thermal Stress by Impeding ESCRT-0-Mediated Autophagic Flux in Epidermal Thermoresistance.

Shan Wu, Qing Pei, Wei Ni, Xiujun Fu, Wen Zhang, Chenlu Song, Yinbo Peng, Qige Guo, Jiying Dong, Min Yao,

Thermoresistance is a physiological phenomenon relevant to noninvasive laser treatments for skin esthetics and tumor removal, although the underlying mechanism remains elusive. We hypothesized that HSPA1A may regulate autophagy by reducing ESCRT-0/STAM2 levels, which could lead to thermal protection from cell death. In this study, we showed that thermoresistance was ... Read more >>

J. Invest. Dermatol. (The Journal of investigative dermatology)
[2020, :]

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Molecular networking uncovers steroidal saponins of Paris tengchongensis.

Jie Wang, Dan Li, Wei Ni, Xu-Jie Qin, Hui Liu, Ling-Ling Yu, Xue Qiao, Yun-Heng Ji, Li He, Si-Hui Nian, Hai-Yang Liu,

Based on a method combining the LC-MS/MS molecular networking strategy with the conventional means of phytochemical research, the chemical constituents and the availability of Paris tengchongensis, a new species found in 2017 from Yunnan Province, were investigated for the first time. The molecular networking showed that this species contained the ... Read more >>

Fitoterapia (Fitoterapia)
[2020, 145:104629]

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Silicone Oil-Associated Extensive Intraocular Ossification: A case report.

Yinhao Wang, Wei Cui, Rongjun Liu, Yanjie Tian, Wei Ni, Changlei Zhou,

BACKGROUND:Intraocular ossification is an uncommon calcium deposition process associated with trauma, chronic inflammation, tumor, and long-standing retinal detachment. This is the first reported extensive intraocular bone formation associated with silicone oil. CASE PRESENTATION:A 30-year-old Han Chinese man came to us with complaint of red, painful blind right eye. He had ... Read more >>

Eur J Ophthalmol (European journal of ophthalmology)
[2020, :1120672120925785]

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Factors associated with negative conversion of viral RNA in patients hospitalized with COVID-19.

Xiaowen Hu, Yuhan Xing, Jing Jia, Wei Ni, Jiwei Liang, Dan Zhao, Xin Song, Ruqin Gao, Fachun Jiang,

Factors associated with negative conversion of SARS-CoV-2 RNA in hospitalized patients have not yet been systematically determined. We conducted a retrospective cohort study of COVID-19 patients in Qingdao, China. Both univariate and multivariate analysis were performed to identify independent factors for time to viral RNA negative conversion. Data on patients ... Read more >>

Sci. Total Environ. (The Science of the total environment)
[2020, 728:138812]

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The association between ambient air pollution and scarlet fever in Qingdao, China, 2014-2018: a quantitative analysis

Xiaowen Hu, Tao Wei, Yalin Han, Jing Jia, Bei Pan, Fachun Jiang, Wei Ni,

Abstract Background: We conducted a distributed lag non-linear time series analysis to quantify the association between air pollution and scarlet fever in Qingdao city during 2014-2018. Methods: A generalized additive Mixed Model (GAMM) combined with a distributed lag non-linear model (DLNM) was applied to quantify the distributed lag effects of ... Read more >>

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Dynamics of faecal SARS-CoV-2 in infected children during the convalescent phase.

Yuhan Xing, Wei Ni, Qin Wu, Wenjie Li, Guoju Li, Wendi Wang, Jianning Tong, Xiufeng Song, Gary Wing Kin Wong, Quansheng Xing,

J. Infect. (The Journal of infection)
[2020, :]

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Polyphyllosides A-F, six new spirostanol saponins from the stems and leaves of Paris polyphylla var. chinensis.

Xu-Jie Qin, Lan-Jun Zhang, Yu Zhang, Wei Ni, Xing-Zhi Yang, Qian Yu, Huan Yan, Lin-Kun An, Hai-Yang Liu,

The first phytochemical investigation on the steroidal saponins from the stems and leaves of Paris polyohylla var. chinensis led to the discovery and characterization of six new spirostanol saponins, named polyphyllosides A-F (1-6), along with four known analogues (7-10). Their structures were unambiguously established via extensive spectroscopic data and chemical ... Read more >>

Bioorg. Chem. (Bioorganic chemistry)
[2020, 99:103788]

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Prolonged viral shedding in feces of pediatric patients with coronavirus disease 2019.

Yu-Han Xing, Wei Ni, Qin Wu, Wen-Jie Li, Guo-Ju Li, Wen-Di Wang, Jian-Ning Tong, Xiu-Feng Song, Gary Wing-Kin Wong, Quan-Sheng Xing,

OBJECTIVE:To determine the dynamic changes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in respiratory and fecal specimens in children with coronavirus disease 2019 (COVID-19). METHODS:From January 17, 2020 to February 23, 2020, three paediatric cases of COVID-19 were reported in Qingdao, Shandong Province, China. Epidemiological, clinical, laboratory, and ... Read more >>

J Microbiol Immunol Infect (Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi)
[2020, 53(3):473-480]

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Analysis of pituitary transcriptomics indicates that lncRNAs are involved in the regulation of sheep estrus.

Xiaoyue Li, Cunyuan Li, Yueren Xu, Rui Yao, Huixiang Li, Wei Ni, Renzhe Quan, Mengdan Zhang, Li Liu, Shuting Yu, Yaseen Ullah, Ruirui Hu, Yaxin Li, Tao Guo, Xiaokui Wang, Shengwei Hu,

Seasonal estrus is a key factor limiting animal fertility, and understanding the molecular mechanisms that regulate animal estrus is important for improving animal fertility. The pituitary gland, which is the most important endocrine gland in mammals, plays an important role in regulating the physiological processes such as growth, development, and ... Read more >>

Funct. Integr. Genomics (Functional & integrative genomics)
[2020, 20(4):563-573]

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Prolonged presence of SARS-CoV-2 in feces of pediatric patients during the convalescent phase

Yuhan Xing, Wei Ni, Qin Wu, Wenjie Li, Guoju Li, Jianning Tong, Xiufeng Song, Quansheng Xing,

Background: Severe acute respiratory coronavirus 2 (SARS-CoV-2) is a newly identified virus which mainly spreads from person-to-person. Fecal shedding of SARS-CoV-2 has been constantly reported in patients with coronavirus disease 2019 (COVID-19). Most published studies focus on adult populations, whereas data concerning pediatric patients is relatively scarce. Methods: From January ... Read more >>

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Precautions are Needed for COVID-19 Patients with Coinfection of Common Respiratory Pathogens

Quansheng Xing, Guoju Li, Yuhan Xing, Ting Chen, Wenjie Li, Wei Ni, Kai Deng, Ruqin Gao, Changzheng Chen, Yang Gao, Qiang Li, Guiling Yu, Jianning Tong, Wei Li, Guiliang Hao, Yue Sun, Ai Zhang, Qin Wu, Zipu Li, Silin Pan,

Background: With the ongoing outbreak of Coronavirus Disease 2019 (COVID-19), infected patients within and beyond the epidemic area, Wuhan, China, showed different epidemiological and clinical characteristics. There is a paucity of data concerning coinfection with other common respiratory pathogens in COVID-19 patients outside of Wuhan. Methods: We conducted a double-centre ... Read more >>

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Identification and Profiling of Pituitary microRNAs of Sheep during Anestrus and Estrus Stages.

Yaseen Ullah, Cunyuan Li, Xiaoyue Li, Wei Ni, Rui Yao, Yueren Xu, Renzhe Quan, Huixiang Li, Mengdan Zhang, Li Liu, Ruirui Hu, Tao Guo, Yaxin Li, Xiaokui Wang, Shengwei Hu,

MicroRNAs (miRNAs) are a class of small non-coding RNAs, molecules of 21 to 25 nucleotides in length, that regulate gene expression by binding to their target mRNA and play a significant role in animal development. The expression and role of miRNAs in regulating sheep estrus, however, remain elusive. Transcriptome analysis ... Read more >>

Animals (Basel) (Animals : an open access journal from MDPI)
[2020, 10(3):]

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Fluorine Doped Cagelike Carbon Electrocatalyst: An Insight into the Structure-Enhanced CO Selectivity for CO2 Reduction at High Overpotential.

Wei Ni, Yifei Xue, Xiaogang Zang, Congxin Li, Huaizhi Wang, Zhiyu Yang, Yi-Ming Yan,

The critical bottleneck of electrocatalytic CO2 reduction reaction (CO2RR) lies in its low efficiency at high overpotential caused by competitive hydrogen evolution. It is challenging to develop an efficient catalyst achieving both high current density and high Faradaic efficiency (FE) for CO2RR. Herein, we synthesized fluorine-doped cagelike porous carbon (F-CPC) ... Read more >>

ACS Nano (ACS nano)
[2020, 14(2):2014-2023]

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TPGS-1000 exhibits potent anticancer activity for hepatocellular carcinoma in vitro and in vivo.

Yidan Chen, Liqin Mo, Xuan Wang, Bi Chen, Yunfen Hua, Linyan Gong, Fei Yang, Yongqiang Li, Fangfang Chen, Guiting Zhu, Wei Ni, Cheng Zhang, Yuming Cheng, Yan Luo, Junping Shi, Mengsheng Qiu, Shixiu Wu, Zhou Tan, Kaifeng Wang,

D-alpha-tocopheryl polyethylene glycol 1000 succinate (TPGS1000) is the most active water-soluble derivative of vitamin E and has been widely used as a carrier of solvents, plasticizers, emulsifiers, absorbent agents and refractory drug delivery systems. However, its anti-hepatocellular carcinoma (HCC) properties have not been explored. HCC cells were treated with different ... Read more >>

Aging (Albany NY) (Aging)
[2020, 12(2):1624-1642]

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Spirostanol and sesquiterpenoid glycosides from the rhizomes of Trillium tschonoskii.

Dan Li, Huan Yan, Jie Wang, Qian Yu, Wei Ni, Lin-Kun An, Xu-Jie Qin, Hai-Yang Liu,

Three new spirostanol glycosides, trilliumosides K-M (1-3), one new sesquiterpenoid glycoside, tritschsesuquiside A (4), along with three known analogues (5-7) were obtained from the rhizomes of Trillium tschonoskii. The structures of new glycosides were elucidated by spectroscopic analyses (HRMS and NMR) and chemical methods. Glycosides 5-7 displayed cytotoxicities against five ... Read more >>

Steroids (Steroids)
[2020, 155:108569]

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Pharmacokinetics and Acute Toxicity of a Histone Deacetylase Inhibitor, Scriptaid, and its Neuroprotective Effects in Mice After Intracranial Hemorrhage.

Heng Yang, Xinjie Gao, Jiabin Su, Hanqiang Jiang, Yu Lei, Wei Ni, Yuxiang Gu,

BACKGROUND & OBJECTIVE:The pharmacokinetics and acute toxicity of a histone deacetylase inhibitor, Scriptaid, was unknown in the mouse. The aim of this study was to determine the pharmacokinetics, acute toxicity, and tissue distribution of Scriptaid, a new histone deacetylase inhibitor, in mice, and its neuroprotective efficacy in a mouse intracranial ... Read more >>

CNS Neurol Disord Drug Targets (CNS & neurological disorders drug targets)
[2020, 19(1):55-65]

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Enhanced Electrosorption Ability of Carbon Nanocages as an Advanced Electrode Material for Capacitive Deionization.

Xiaogang Zang, Yifei Xue, Wei Ni, Congxin Li, Lingyuan Hu, Anqi Zhang, Zhiyu Yang, Yi-Ming Yan,

The structure of an electrode material has an important impact on the performance of a capacitive deionization (CDI) device. However, it is still a challenge to design and synthesize electrode materials with a rational structure based on deep understanding of their structure-dependent CDI performance. Herein, we report the preparation of ... Read more >>

ACS Appl Mater Interfaces (ACS applied materials & interfaces)
[2020, 12(2):2180-2190]

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Chinese Stroke Association guidelines for clinical management of cerebrovascular disorders: executive summary and 2019 update of clinical management of spontaneous subarachnoid haemorrhage.

Yi Dong, Zhen-Ni Guo, Qi Li, Wei Ni, Hongqiu Gu, Yu-Xiang Gu, Qiang Dong, ,

Aim:Spontaneous subarachnoid haemorrhage (SAH) caused by ruptured cerebral aneurysm is a severe subtype of haemorrhagic stroke. Although the incidence of SAH is relatively low among all cerebrovascular diseases, the mortality is the highest. The critical management of SAH is challenging. We provide this evidence-based guideline to present current and comprehensive ... Read more >>

Stroke Vasc Neurol (Stroke and vascular neurology)
[2019, 4(4):176-181]

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Establishing an animal model to investigate depression with coronary heart disease.

Chun-Xia Guo, Fei Zheng, Yi-Ran Feng, Yu-Dong Rao, Ying Zhang, Zong-Ren Ma, Yan-Fang Zeng, Hao Zhou, Kun-Rong Yang, Wei Ni, Xue-Ya Zhang,

Chin. Med. J. (Chinese medical journal)
[2019, 132(24):3021-3023]

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Circ-HIPK3 plays an active role in regulating myoblast differentiation.

Rui Yao, Yang Yao, Cunyuan Li, Xiaoyue Li, Wei Ni, Renzhe Quan, Li Liu, Huixiang Li, Yueren Xu, Mengdan Zhang, Yaseen Ullah, Shengwei Hu,

The development of skeletal muscle is a complex biological process involving a variety of regulatory pathways. A deeper understanding of the developmental mechanisms of skeletal muscle is of great significance for the treatment of muscular lesions. In recent years, studies have shown that circRNAs, as a new class of post-transcriptional ... Read more >>

Int. J. Biol. Macromol. (International journal of biological macromolecules)
[2020, 155:1432-1439]

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Portable and Field-Ready Detection of Circulating MicroRNAs with Paper-Based Bioluminescent Sensing and Isothermal Amplification.

Yong Li, Lanlan Zhou, Wei Ni, Qingying Luo, Chunnan Zhu, Yunhua Wu,

We present a paper-based system that integrates bioluminescence resonance energy transfer (BRET) and isothermal amplification for the analysis of tumor-associated circulating microRNAs (miRNAs) in clinical serum samples. The analysis procedure could be easily accomplished with two pieces of functionalized paper and a low-cost smartphone-based device, which enables sequence-specific quantification of ... Read more >>

Anal. Chem. (Analytical chemistry)
[2019, 91(23):14838-14841]

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