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Author Wei Li

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ctc-[Pt(NH3)2(cinnamate)(valproate)Cl2] is a highly potent and low-toxic triple action anticancer prodrug.

Yang Li, Shan Shi, Shurong Zhang, Zongjie Gan, Xin Wang, Xudong Zhao, Yijian Zhu, Meiting Cao, Xiaoyue Wang, Wei Li,

Pt(iv) prodrugs have gained tremendous attention due to their indisputable advantages compared to cisplatin. Herein, new Pt(iv) derivatives with cinnamic acid at the first axial position, and inhibitor of matrix metalloproteinases-2 and -9, histone deacetylase, cyclooxygenase or pyruvate dehydrogenase at the second axial position are constructed to develop multi-action prodrugs. ... Read more >>

Dalton Trans (Dalton transactions (Cambridge, England : 2003))
[2021, 50(32):11180-11188]

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Deoxyfluorination of alcohols with aryl fluorosulfonates.

Xiu Wang, Min Zhou, Qinghe Liu, Chuanfa Ni, Zhongbo Fei, Wei Li, Jinbo Hu,

Aryl fluorosulfonates are developed as a deoxyfluorinating reagent in the transformation of primary and secondary alcohols into the corresponding alkyl fluorides. These reagents feature easy availability, low-cost, high stability and high efficiency. Diverse functionalities including aldehyde, ketone, ester, halogen, nitro, alkene, and alkyne are well tolerated under mild reaction conditions. ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2021, 57(66):8170-8173]

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Ab initio nonadiabatic molecular dynamics of charge carriers in metal halide perovskites.

Wei Li, Yalan She, Andrey S Vasenko, Oleg V Prezhdo,

Photoinduced nonequilibrium processes in nanoscale materials play key roles in photovoltaic and photocatalytic applications. This review summarizes recent theoretical investigations of excited state dynamics in metal halide perovskites (MHPs), carried out using a state-of-the-art methodology combining nonadiabatic molecular dynamics with real-time time-dependent density functional theory. The simulations allow one to ... Read more >>

Nanoscale (Nanoscale)
[2021, 13(23):10239-10265]

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A near-infrared light-controlled, oxygen-independent radical generating nano-system toward cancer therapy.

Desheng Cao, Hua He, Wei Li, Jin Yan, Jianhua Wu, Mengyuan Yin, Yang Zhou, Zhuchao Zhou, Lichen Yin,

Anti-tumor treatment based on free radicals is often inefficient in hypoxic tumors, mainly because of the oxygen-dependent generation mechanism of reactive oxygen species (ROS). Herein, we report an NIR laser-controlled nano-system that is capable of generating alkyl radicals in situ in an oxygen-independent approach. Hollow mesoporous Prussian blue nanoparticles (HPB ... Read more >>

Biomater Sci (Biomaterials science)
[2021, 9(11):4054-4065]

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The effect of different covalent bond connections and doping on transport properties of planar graphene/MoS2/graphene heterojunctions.

Wei Li, Jinlei Wei, Baoan Bian, Bin Liao, Guoliang Wang,

The electronic transport properties of in-plane graphene/MoS<sub>2</sub>/graphene heterojunctions are studied using density functional theory and the nonequilibrium Green's function method. It is found that different covalent bond connections cause different electron distributions, such as accumulation or depletion, on the contact surface. The C-S structure exhibits more electron accumulation and depletion, ... Read more >>

Phys Chem Chem Phys (Physical chemistry chemical physics : PCCP)
[2021, 23(11):6871-6879]

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Distinct structure assembly driven by metal-ligand binding in Au23 nanoclusters and its relation to photocatalysis.

Shuohao Li, Yongnan Sun, Chenyang Wu, Weigang Hu, Wei Li, Xu Liu, Mingyang Chen, Yan Zhu,

Here, we introduce two Au<sub>23</sub> nanoclusters to unveil the significance of metal-ligand binding-induced assembly. The Au<sub>23</sub> cluster protected by the thiolate ligand is packed in the shell-by-shell arrangement, while the Au<sub>23</sub> cluster capped by dual ligands of thiolate and PPh<sub>3</sub> is constructed from the assembly of Au<sub>4</sub> tetrahedra. Furthermore Au<sub>23</sub> ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2021, 57(17):2176-2179]

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Non-stoichiometric molybdenum sulfide clusters and their reactions with the hydrogen molecule.

Yan Chen, Jia-Jun Deng, Wen-Wen Yao, Joseph Israel Gurti, Wei Li, Wen-Jie Wang, Jian-Xi Yao, Xun-Lei Ding,

Structures of non-stoichiometric MoxSy clusters (x = 2-4; y = 2-10) were studied by density functional calculations with global optimization. Besides 1T phase like structures, a novel regular grid structure in which Mo atoms are well separated by S atoms was found, which might be used as a building-block to ... Read more >>

Phys Chem Chem Phys (Physical chemistry chemical physics : PCCP)
[2021, 23(1):347-355]

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Direct monitoring of protease activity using an integrated microchip coated with multilayered fluorogenic nanofilms.

Dan Yu, Yuting Chen, Caroline C Ahrens, Yinggui Wang, Zhenya Ding, HyunTaek Lim, Cody Fell, Kendra P Rumbaugh, Jiangyu Wu, Wei Li,

Proteases play an essential role in the four sequential but overlapping phases of wound healing: hemostasis, inflammation, proliferation, and remodeling. In chronic wounds, excessive protease secretion damages the newly formed extracellular matrix, thereby delaying or preventing the normal healing process. Peptide-based fluorogenic sensors provide a visual platform to sense and ... Read more >>

Analyst (The Analyst)
[2021, 145(24):8050-8058]

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Machine-Based Hand Massage Ameliorates Preoperative Anxiety in Patients Awaiting Ambulatory Surgery.

Cheng-Hua Ni, Li Wei, Chia-Che Wu, Chueh-Ho Lin, Pao-Yu Chou, Yeu-Hui Chuang, Ching-Chiu Kao,

<h4>Background</h4>Hand massage therapies have been used to relieve anxiety and pain in various clinical situations. The effects of machine-based hand massage on preoperative anxiety in ambulatory surgery settings have not been evaluated.<h4>Purpose</h4>This prospective study was designed to investigate the effect of machine-based hand massage on preoperative anxiety and vital signs ... Read more >>

J Nurs Res (The journal of nursing research : JNR)
[2021, 29(3):e152]

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Assessment of the effect of lactic acid fermentation on the gastroduodenal digestibility and immunoglobulin E binding capacity of soy proteins via an in vitro dynamic gastrointestinal digestion model.

Jin Huang, Zhen Liu, Xin Rui, Lamia L'Hocine, Qiuqin Zhang, Wei Li, Mingsheng Dong,

Fermentation by lactic acid bacteria is helpful in reducing soy protein immunoreactivity. However, how lactic acid fermentation influences the gastroduodenal digestibility and immunoglobulin E (IgE) binding capacity of soy proteins remains unclear. In this study, the protein digestion of a fermented soybean protein isolate (FSPI) was investigated and compared with ... Read more >>

Food Funct (Food & function)
[2020, 11(12):10467-10479]

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Long intergenic non-protein coding RNA 02570 promotes nasopharyngeal carcinoma progression by adsorbing microRNA miR-4649-3p thereby upregulating both sterol regulatory element binding protein 1, and fatty acid synthase.

Fei Liu, Jiazhang Wei, Yanrong Hao, Jiao Lan, Wei Li, Jingjin Weng, Min Li, Cheng Su, Bing Li, Mingzheng Mo, Fengzhu Tang, Yongli Wang, Yong Yang, Wei Jiao, Shenhong Qu,

Our previous studies have elucidated a possible connection between long intergenic non-protein coding RNA 2570 (LINC02570) and nasopharyngeal carcinoma (NPC). However, the precise mechanism by which LINC02570 promotes NPC remains unknown. We used quantitative polymerase chain reaction (qPCR) to detect LINC02570 expression in nasopharyngeal cell lines, NPC tissues, and chronic ... Read more >>

Bioengineered (Bioengineered)
[2021, 12(1):7119-7130]

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Long coding RNA CCAT2 enhances the proliferation and epithelial-mesenchymal transition of cervical carcinoma cells via the microRNA-493-5p/CREB1 axis.

Jing Wang, Yan Liu, Hongbing Cai, Hong Jiang, Wei Li, Yuying Shi,

Cervical cancer (CC) is one of the most common malignancies among women. It has been demonstrated that long coding RNAs (lncRNAs) play a crucial role in CC. The purpose of this study was to investigate the role of the colon cancer associated transcript 2 (CCAT2) lncRNA in CC and elucidate ... Read more >>

Bioengineered (Bioengineered)
[2021, 12(1):6264-6274]

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Overexpression of ADAM9 decreases radiosensitivity of hepatocellular carcinoma cell by activating autophagy.

Lijin Zhu, Yuanyuan Zhao, Li Yu, Xinjia He, Yingju Wang, Peng Jiang, Rong Yu, Wei Li, Bin Dong, Xiang Wang, Yinying Dong,

A disintegrin and a metalloprotease (ADAM)9 upregulated within human hepatocellular carcinoma (HCC) cells, but its effect on HCC radiosensitivity remains unknown. The present work aimed to examine the effect of ADAM9 on HCC radiosensitivity and to reveal its possible mechanism, which may be helpful in identifying a potential therapeutic strategy. ... Read more >>

Bioengineered (Bioengineered)
[2021, 12(1):5516-5528]

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Curcumin induces apoptosis and autophagy inhuman renal cell carcinoma cells via Akt/mTOR suppression.

Xuelian Gong, Ling Jiang, Wei Li, Qingbin Liang, Zhen Li,

Renal cell carcinoma (RCC) is a highly aggressive cancer leading to high economic and social burden, and has increasing annual cases. Curcumin is a traditional Chinese medicine widely used as anti-inflammatory, anti-viral and anti-cancer agent, thus can be applicable in RCC therapy. The work assessed the effects of RCC treatment ... Read more >>

Bioengineered (Bioengineered)
[2021, 12(1):5017-5027]

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Bio-herbicidal potential of wheat rhizosphere bacteria on Avena fatua L. grass.

Wei Li, Shuo Shen, Hongyu Chen,

In order to isolated and identified the bacterial strains from wheat rhizosphere and evaluated the effect of different concentration of bacterial fermentation broth on the wild oats weed growth. This experiment carried out the separation and purification of dominant bacterial strains from the wheat rhizosphere soil, and performed the fermentation ... Read more >>

Bioengineered (Bioengineered)
[2021, 12(1):516-526]

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Hippocampal insulin resistance and the Sirtuin 1 signaling pathway in diabetes-induced cognitive dysfunction.

Hui Yang, Lin Tang, Zhan Qu, Shi-Hui Lei, Wei Li, Yu-Hong Wang,

In the peripheral nervous system, the activation of Sirtuin 1 can improve insulin resistance; however, the role played by Sirtuin 1 in the central nervous system remains unknown. In this study, rat models of diabetes mellitus were generated by a single injection of streptozotocin. At 8 weeks after streptozotocin injection, ... Read more >>

Neural Regen Res (Neural regeneration research)
[2021, 16(12):2465-2474]

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Anticancer potential of an exopolysaccharide from Lactobacillus helveticus MB2-1 on human colon cancer HT-29 cells via apoptosis induction.

Luyao Xiao, Xiaojia Ge, Lin Yang, Xiaohong Chen, Qian Xu, Xin Rui, Xia Fan, Li Feng, Qiuqin Zhang, Mingsheng Dong, Wei Li,

This study aimed at investigating the anticancer activity of an exopolysaccharide (EPS) isolated from Lactobacillus helveticus MB2-1. The crude EPS from L. helveticus MB2-1 (LHEPS) was fractionated into three fractions, namely LHEPS-1, LHEPS-2 and LHEPS-3. LHEPS-1 exhibited the most effective anti-proliferative activity, which was associated with a stronger inhibition rate ... Read more >>

Food Funct (Food & function)
[2020, 11(11):10170-10181]

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Tunable phase transitions and high photovoltaic performance of two-dimensional In2Ge2Te6 semiconductors.

Naihua Miao, Wei Li, Linggang Zhu, Bin Xu, Jian Zhou, Stephen R Elliott, Zhimei Sun,

Ultrathin semiconductors with great electrical and photovoltaic performance hold tremendous promise for fundamental research and applications in next-generation electronic devices. Here, we report new 2D direct-bandgap semiconductors, namely mono- and few-layer In<sub>2</sub>Ge<sub>2</sub>Te<sub>6</sub>, with a range of desired properties from ab initio simulations. We suggest that 2D In<sub>2</sub>Ge<sub>2</sub>Te<sub>6</sub> samples should be ... Read more >>

Nanoscale Horiz (Nanoscale horizons)
[2020, 5(12):1566-1573]

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Nanoscale Phase Separation in Ternary Organic Solar Cells Based on PTB7:PC70BM:IC70BA.

Chang Li, Wei Li, Xiaoxiang Sun, Jifei Wang, Jiayou Tao, Zhijun Zou, Gaohua Liao, Xinchang Zou, Jian Ni, Jianjun Zhang,

As a fullerene derivative, IC<sub>70</sub>BA is widely used in the ternary organic solar cells (TOSCs) to increase the open circuit voltage (V<sub>oc</sub>) of the devices. Unfortunately, most of the literature shows that IC<sub>70</sub>BA will lead to a reduction in the short-circuit current density (J<sub>sc</sub>) and fill factor (FF). In this ... Read more >>

J Nanosci Nanotechnol (Journal of nanoscience and nanotechnology)
[2021, 21(11):5749-5755]

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Correction: Efficient photocatalytic hydrogen evolution over hydrogenated ZnO nanorod arrays.

Xihong Lu, Gongming Wang, Shilei Xie, Jianying Shi, Wei Li, Yexiang Tong, Yat Li,

Correction for 'Efficient photocatalytic hydrogen evolution over hydrogenated ZnO nanorod arrays' by Xihong Lu et al., Chem. Commun., 2012, 48, 7717-7719, DOI: . ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2020, 56(71):10378]

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Rapid and simple detection of Bacillus cereus in milk by real-time competitive annealing mediated isothermal amplification.

Haiyan Bao, Wei Li, Xiqing Yue, Junrui Wu, Yu Qiao, Qing Peng, Bo Shi, Yuguang Du, Xu Chen, Rina Wu,

Bacillus cereus (B. cereus) is widespread in nature and considered an important foodborne pathogen, which can lead to emetic syndrome and diarrheal illness. Therefore, appropriate detection methods are needed to effectively monitor this pathogenic bacterium. Competitive annealing mediated isothermal amplification (CAMP) is a novel nucleic-acid-based detection technology that amplifies DNA ... Read more >>

Analyst (The Analyst)
[2020, 145(20):6677-6682]

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Introduction of octenylsuccinate and carboxymethyl onto starch for strong bonding to fiber and easy removal from sized yarn

Zhifeng Zhu, Yanzhi Song, Zhenzhen Xu, Wei Li, Chaohui Zhang,

Amphipathic starch (AS) with hydrophobic octenylsuccinate (OS) and hydrophilic carboxymethyl (CM) substituents was prepared by the carboxymethylation and octenylsuccinylation of starch for strong bonding to fiber and easy removal from sized yarn. Two series of AS derivatives with differential degrees of substitution (DS) and differential mole percentages of OS to ... Read more >>

(Carbohydrate polymers.)
[2021, 269:Not Available]

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Investigation of phytochemical composition and metabolite profiling in vivo of Beta vulgaris L.

Xiaoyong Zhang, Xuezhao Chen, Wei Li, Wei Zhu, Zhiwei Ge, Minghua Gong, Shouxin Li, Jingkui Tian,

<h4>Rationale</h4>Beta vulgaris L. has attracted increasing attention because of its broad application. The root of B. vulgaris L. (beetroot) possesses many excellent biological properties such as antianemic, anti-inflammatory, antihypertensive, antioxidant, anticarcinogenic, antipyretic, antibacterial, detoxicant, and diuretic. The chemical constituents of beetroot play a major role in the research on beetroot ... Read more >>

Rapid Commun Mass Spectrom (Rapid communications in mass spectrometry : RCM)
[2021, 35(19):e9172]

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High Hemoglobin glycation index is associated with telomere attrition independent of HbA1c, mediating by TNFα.

Lu Lyu, Jie Yu, Yiwen Liu, Shuli He, Yuan Zhao, Mengya Qi, Fan Ping, Lingling Xu, Wei Li, Huabing Zhang, Yuxiu Li,

<h4>Context</h4>The hemoglobin glycation index(HGI) is correlated with metabolic diseases and inflammations. Whether the HGI is associated with the ageing process and how inflammation and oxidative stress affect the relationship remain unclear.<h4>Objective</h4>We aim to analyze links between HGI and ageing biomarkers, and to explore a potential role of inflammation and oxidative ... Read more >>

J Clin Endocrinol Metab (The Journal of clinical endocrinology and metabolism)
[2021, :]

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Improved method to stratify lymphoma patients with risk of secondary central nervous system involvement: A multicenter retrospective analysis.

Mingxiao Lang, Youqin Feng, Xiangrui Meng, Jing Zhao, Zheng Song, Zhengzi Qian, Lihua Qiu, Shiyong Zhou, Xianming Liu, Lanfang Li, Haiyan Yang, Yuqin Song, Wei Li, Huilai Zhang,

Secondary central nervous system (SCNS) involvement is an infrequent but universally fatal event in diffused large B-cell lymphoma. The occurrence rate of SCNS involvement is approximately 5% but comes with a poor prognosis ever after. However, existing risk models to predict the incidence and prognosis of these patients with SCNS ... Read more >>

Hematol Oncol (Hematological oncology)
[2021, :]

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