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Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021.

Laura Evans, Andrew Rhodes, Waleed Alhazzani, Massimo Antonelli, Craig M Coopersmith, Craig French, Flávia R Machado, Lauralyn Mcintyre, Marlies Ostermann, Hallie C Prescott, Christa Schorr, Steven Simpson, W Joost Wiersinga, Fayez Alshamsi, Derek C Angus, Yaseen Arabi, Luciano Azevedo, Richard Beale, Gregory Beilman, Emilie Belley-Cote, Lisa Burry, Maurizio Cecconi, John Centofanti, Angel Coz Yataco, Jan De Waele, R Phillip Dellinger, Kent Doi, Bin Du, Elisa Estenssoro, Ricard Ferrer, Charles Gomersall, Carol Hodgson, Morten Hylander Møller, Theodore Iwashyna, Shevin Jacob, Ruth Kleinpell, Michael Klompas, Younsuck Koh, Anand Kumar, Arthur Kwizera, Suzana Lobo, Henry Masur, Steven McGloughlin, Sangeeta Mehta, Yatin Mehta, Mervyn Mer, Mark Nunnally, Simon Oczkowski, Tiffany Osborn, Elizabeth Papathanassoglou, Anders Perner, Michael Puskarich, Jason Roberts, William Schweickert, Maureen Seckel, Jonathan Sevransky, Charles L Sprung, Tobias Welte, Janice Zimmerman, Mitchell Levy,

Crit Care Med (Critical care medicine)
[2021, 49(11):e1063-e1143]

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Executive Summary: Surviving Sepsis Campaign: International Guidelines for the Management of Sepsis and Septic Shock 2021.

Laura Evans, Andrew Rhodes, Waleed Alhazzani, Massimo Antonelli, Craig M Coopersmith, Craig French, Flávia R Machado, Lauralyn Mcintyre, Marlies Ostermann, Hallie C Prescott, Christa Schorr, Steven Simpson, W Joost Wiersinga, Fayez Alshamsi, Derek C Angus, Yaseen Arabi, Luciano Azevedo, Richard Beale, Gregory Beilman, Emilie Belley-Cote, Lisa Burry, Maurizio Cecconi, John Centofanti, Angel Coz Yataco, Jan De Waele, R Phillip Dellinger, Kent Doi, Bin Du, Elisa Estenssoro, Ricard Ferrer, Charles Gomersall, Carol Hodgson, Morten Hylander Møller, Theodore Iwashyna, Shevin Jacob, Ruth Kleinpell, Michael Klompas, Younsuck Koh, Anand Kumar, Arthur Kwizera, Suzana Lobo, Henry Masur, Steven McGloughlin, Sangeeta Mehta, Yatin Mehta, Mervyn Mer, Mark Nunnally, Simon Oczkowski, Tiffany Osborn, Elizabeth Papathanassoglou, Anders Perner, Michael Puskarich, Jason Roberts, William Schweickert, Maureen Seckel, Jonathan Sevransky, Charles L Sprung, Tobias Welte, Janice Zimmerman, Mitchell Levy,

Crit Care Med (Critical care medicine)
[2021, 49(11):1974-1982]

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Prognostic Factors Associated With Development of Venous Thromboembolism in Critically Ill Patients-A Systematic Review and Meta-Analysis.

Alexandre Tran, Shannon M Fernando, Bram Rochwerg, Deborah J Cook, Mark A Crowther, Robert A Fowler, Waleed Alhazzani, Deborah M Siegal, Lana A Castellucci, Ryan Zarychanski, Shane W English, Kwadwo Kyeremanteng, Marc Carrier,

<h4>Objective</h4>To identify prognostic factors for the development of venous thromboembolism in the ICU.<h4>Data sources</h4>We searched MEDLINE, EMBASE, and Cochrane CENTRAL from inception to March 1, 2021.<h4>Study selection</h4>We included English-language studies describing prognostic factors associated with the development of venous thromboembolism among critically ill patients.<h4>Data extraction</h4>Two authors performed data extraction and ... Read more >>

Crit Care Med (Critical care medicine)
[2021, :]

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Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021.

Laura Evans, Andrew Rhodes, Waleed Alhazzani, Massimo Antonelli, Craig M Coopersmith, Craig French, Flávia R Machado, Lauralyn Mcintyre, Marlies Ostermann, Hallie C Prescott, Christa Schorr, Steven Simpson, W Joost Wiersinga, Fayez Alshamsi, Derek C Angus, Yaseen Arabi, Luciano Azevedo, Richard Beale, Gregory Beilman, Emilie Belley-Cote, Lisa Burry, Maurizio Cecconi, John Centofanti, Angel Coz Yataco, Jan De Waele, R Phillip Dellinger, Kent Doi, Bin Du, Elisa Estenssoro, Ricard Ferrer, Charles Gomersall, Carol Hodgson, Morten Hylander Møller, Theodore Iwashyna, Shevin Jacob, Ruth Kleinpell, Michael Klompas, Younsuck Koh, Anand Kumar, Arthur Kwizera, Suzana Lobo, Henry Masur, Steven McGloughlin, Sangeeta Mehta, Yatin Mehta, Mervyn Mer, Mark Nunnally, Simon Oczkowski, Tiffany Osborn, Elizabeth Papathanassoglou, Anders Perner, Michael Puskarich, Jason Roberts, William Schweickert, Maureen Seckel, Jonathan Sevransky, Charles L Sprung, Tobias Welte, Janice Zimmerman, Mitchell Levy,

Intensive Care Med (Intensive care medicine)
[2021, :]

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Outcomes of sutureless aortic valve replacement versus conventional aortic valve replacement and transcatheter aortic valve replacement, updated systematic review, and meta-analysis.

Kevin S Kim, Ahmad Makhdoum, Alex Koziarz, Saurabh Gupta, Ali Alsagheir, Arjun Pandey, Seleman Reza, Kevin Um, Kevin Teoh, Waleed Alhazzani, André Lamy, Bobby Yanagawa, Emilie P Belley-Côté, Richard P Whitlock,

<h4>Background</h4>Sutureless aortic valve replacement (SuAVR) is an alternative to surgical aortic valve replacement (SAVR) and transcatheter aortic valve replacement (TAVR). This study compares the effectiveness of SuAVR to SAVR and TAVR.<h4>Methods</h4>We searched MEDLINE and EMBASE from inception to July 2021 for studies evaluating SuAVR, SAVR, and TAVR in adults with ... Read more >>

J Card Surg (Journal of cardiac surgery)
[2021, :]

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Ketamine administration for acute painful sickle cell crisis: A randomized controlled trial.

Mohammed S Alshahrani, Amal H AlSulaibikh, Mohamed R ElTahan, Sukayna Z AlFaraj, Laila P Asonto, Abdullah A AlMulhim, Murad F AlAbbad, Nisreen Almaghraby, Mohammed A AlJumaan, Thamir O AlJunaid, Moath N Darweesh, Faisal M AlHawaj, Alaa M Mahmoud, Bader K Alossaimi, Shaikhah K Alotaibi, Talal M AlMutairi, Duaa A AlSulaiman PharmD, Dunya Alfaraj, Reem Alhawwas, Lawrence Mbuagbaw, Kim Lewis, Madeleine Verhovsek, Mark Crowther, Gordon Guyatt, Waleed Alhazzani, ,

<h4>Objective</h4>The objective was to evaluate the efficacy and safety of single-dose ketamine infusion in adults with sickle cell disease (SCD) who presented with acute sickle vasoocclusive crisis (VOC).<h4>Methods</h4>This study was a parallel-group, prospective, randomized, double-blind, pragmatic trial. Participants were randomized to receive a single dose of either ketamine or morphine, ... Read more >>

Acad Emerg Med (Academic emergency medicine : official journal of the Society for Academic Emergency Medicine)
[2021, :]

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Awake Prone Position in Hypoxemic Patients with Coronavirus Disease 19 (COVI-PRONE): A Study protocol and Statistical Analysis Plan for Randomized Clinical Trial

Zainab Al Duhailib, Yaseen Arabi, Sarah Culgin, Jason Weatherald, Ken Kuljit Parhar, Kate Nelson, Hani Tamim, Waleed Alhazzani, ,

<h4>Background</h4> Coronavirus disease 2019 (COVID-19), may progress to respiratory failure requiring invasive mechanical ventilation. Due to ventilator shortage and healthcare systems strain, affordable interventions such as awake prone positioning has been used to improve oxygenation, however, the effect of this intervention on patient-important outcomes is uncertain. The COVI-PRONE trial aims ... Read more >>

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Single-dose oral anti-arrhythmic drugs for cardioversion of recent-onset atrial fibrillation: a systematic review and network meta-analysis of randomized controlled trials.

Omar A Ibrahim, Emilie P Belley-Côté, Kevin J Um, Adrian Baranchuk, Alexander P Benz, Shreyash Dalmia, Chang N Wang, Waleed Alhazzani, David Conen, P J Devereaux, Richard P Whitlock, Jeff S Healey, William F McIntyre,

<h4>Aims</h4>Single oral dose anti-arrhythmic drugs (AADs) are used to cardiovert recent-onset atrial fibrillation (AF); however, the optimal agent is uncertain.<h4>Methods</h4>We performed a systematic review and network meta-analysis of randomized trials testing single oral dose AADs vs. any comparator to cardiovert AF <7 days duration. We searched MEDLINE, Embase, and CENTRAL to ... Read more >>

Europace (Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology)
[2021, 23(8):1200-1210]

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Use of COVID-19 vaccines in patients with liver disease and post-liver transplantation: Position statement of the Saudi association for the study of liver diseases and transplantation.

Saleh A Alqahtani, Mazin Barry, Ziad Memish, Almoutaz Hashim, Mona A Alfares, Saad A Alghamdi, Waleed K Al-Hamoudi, Bandar Al-Judaibi, Waleed Alhazzani, Jaffar A Al-Tawfiq, Faisal Abaalkhail,

Patients with chronic liver disease (CLD) and liver transplant recipients are at increased risk of morbidity and mortality from coronavirus disease 2019 (COVID-19). Although several studies demonstrated the safety and efficacy of COVID-19 vaccines in the general population, data in CLD patients and liver transplant recipients are lacking. Two COVID-19 ... Read more >>

Saudi J Gastroenterol (Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association)
[2021, 27(4):201-207]

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Cuff Leak Test and Airway Obstruction in Mechanically Ventilated ICU Patients: A Pilot Randomised Controlled Trial.

Kimberley Lewis, Sarah Culgin, Roman Jaeschke, Dan Perri, Corry Marchildon, Kelly Hassall, Yousef Almubarak, Wojciech Szczeklik, Thomas Piraino, Lehana Thabane, Khaled M Alqahtani, Abdulazez Alghamdi, Mohammed Alshahrani, Waleed Alhazzani, ,

<h4>Rationale</h4>Laryngeal edema is a known complication of endotracheal intubation that may cause airway obstruction upon extubation. The only test available to predict this complication is the cuff leak test (CLT).<h4>Objective</h4>Given the uncertainty of the CLT's clinical utility, we conducted the Cuff Leak Test and Airway Obstruction in Mechanically Ventilated ICU ... Read more >>

Ann Am Thorac Soc (Annals of the American Thoracic Society)
[2021, :]

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The Saudi Critical Care Society Practice Guidelines on the Management of COVID-19 in the ICU: Therapy Section

Waleed Alhazzani, Mohammed Alshahrani, Fayez Alshamsi, Ohoud Aljuhani, Khalid Eljaaly, Samaher Hashim, Rakan Alqahtani, Doaa Alsaleh, Zainab Al Duhailib, Haifa Algethamy, Tariq Al-Musawi, Thamir Alshammari, Abdullah Alqarni, Danya Khoujah, Wail Tashkandi, Talal Dahhan, Najla Almutairi, Haleema Alserehi, Maytha Al-Yahya, Bandar Al-Judaibi, Yaseen Arabi, Jameel Abualenain, Jawaher Alotaibi, Ali Albshabshe, Reham Alharbi, Fahad Al-Hameed, Alyaa Elhazmi, Reem Almaghrabi, Fatma Almaghlouth, Malak Abedalthagafi, Noor Al Khathlan, Faisal Al-Suwaidan, Reem Bunyan, Bandar Baw, Ghassan Alghamdi, Manal Al Hazmi, Yasser Mandourah, Abdullah Assiri, Mushira Enani, Maha Alawi, Reem Aljindan, Ahmed Aljabbary, Abdullah Alrbiaan, Fahd Algurashi, Abdulmohsen Alsaawi, Thamer Alenazi, Mohammed Alsultan, Saleh Alqahtani, Ziad Memish, Jaffar Al-Tawfiq, Ahmed Al-Jedai,

<h4>Background: </h4> The rapid increase in coronavirus disease 2019 (COVID-19) cases during the subsequent waves in Saudi Arabia and other countries prompted the Saudi Critical Care Society (SCCS) to put together a panel of experts to issue evidence-based recommendations for the management of COVID-19 in the intensive care unit (ICU). ... Read more >>

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Comparing Renal Replacement Therapy Modalities in Critically Ill Patients With Acute Kidney Injury: A Systematic Review and Network Meta-Analysis.

Zhikang Ye, Ying Wang, Long Ge, Gordon H Guyatt, David Collister, Waleed Alhazzani, Sean M Bagshaw, Emilie P Belley-Cote, Fang Fang, Liangying Hou, Philipp Kolb, Francois Lamontagne, Simon Oczkowski, Lonnie Pyne, Christian Rabbat, Matt Scaum, Borna Tadayon Najafabadi, Wimonchat Tangamornsuksan, Ron Wald, Qi Wang, Michael Walsh, Liang Yao, Linan Zeng, Abdullah Mohammed Algarni, Rachel J Couban, Paul Elias Alexander, Bram Rochwerg,

<h4>Objectives</h4>To compare different modalities of renal replacement therapy in critically ill adults with acute kidney injury.<h4>Data sources</h4>We searched Medline, PubMed, Embase, Cochrane Central Register of Controlled Trials, and ClinicalTrials.gov from inception to 25 May, 2020. We included randomized controlled trials comparing the efficacy and safety of different renal replacement therapy ... Read more >>

Crit Care Explor (Critical care explorations)
[2021, 3(5):e0399]

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Promoting Evidence-Based Practice in Acute Respiratory Distress Syndrome: A Systematic Review.

Shewit P Giovanni, Ann L Jennerich, Tessa L Steel, Sharukh Lokhandwala, Waleed Alhazzani, Curtis H Weiss, Catherine L Hough,

Low tidal volume ventilation and prone positioning are recommended therapies yet underused in acute respiratory distress syndrome. We aimed to assess the role of interventions focused on implementation of low tidal volume ventilation and prone positioning in mechanically ventilated adult patients with acute respiratory distress syndrome.<h4>Data sources</h4>PubMed, Excerpta Medica Database, ... Read more >>

Crit Care Explor (Critical care explorations)
[2021, 3(4):e0391]

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Corticosteroids in COVID-19 and non-COVID-19 ARDS: a systematic review and meta-analysis.

Dipayan Chaudhuri, Kiyoka Sasaki, Aram Karkar, Sameer Sharif, Kimberly Lewis, Manoj J Mammen, Paul Alexander, Zhikang Ye, Luis Enrique Colunga Lozano, Marie Warrer Munch, Anders Perner, Bin Du, Lawrence Mbuagbaw, Waleed Alhazzani, Stephen M Pastores, John Marshall, François Lamontagne, Djillali Annane, Gianfranco Umberto Meduri, Bram Rochwerg,

<h4>Purpose</h4>Corticosteroids are now recommended for patients with severe COVID-19 including those with COVID-related ARDS. This has generated renewed interest regarding whether corticosteroids should be used in non-COVID ARDS as well. The objective of this study was to summarize all RCTs examining the use of corticosteroids in ARDS.<h4>Methods</h4>The protocol of this ... Read more >>

Intensive Care Med (Intensive care medicine)
[2021, 47(5):521-537]

Cited: 5 times

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Scale-up and sustainability of a personalized end-of-life care intervention: a longitudinal mixed-methods study.

Alyson Takaoka, Benjamin Tam, Meredith Vanstone, France J Clarke, Neala Hoad, Marilyn Swinton, Feli Toledo, Anne Boyle, Anne Woods, Erick H Duan, Diane Heels-Ansdell, Lily Waugh, Mark Soth, Jill Rudkowski, Waleed Alhazzani, Dan Perri, Tania Ligori, Roman Jaeschke, Nicole Zytaruk, Deborah J Cook,

<h4>Background</h4>Scaling-up and sustaining healthcare interventions can be challenging. Our objective was to describe how the 3 Wishes Project (3WP), a personalized end-of-life intervention, was scaled-up and sustained in an intensive care unit (ICU).<h4>Methods</h4>In a longitudinal mixed-methods study from January 12,013 - December 31, 2018, dying patients and families were invited ... Read more >>

BMC Health Serv Res (BMC health services research)
[2021, 21(1):218]

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Surviving Sepsis Campaign Guidelines on the Management of Adults With Coronavirus Disease 2019 (COVID-19) in the ICU: First Update.

Waleed Alhazzani, Laura Evans, Fayez Alshamsi, Morten Hylander Møller, Marlies Ostermann, Hallie C Prescott, Yaseen M Arabi, Mark Loeb, Michelle Ng Gong, Eddy Fan, Simon Oczkowski, Mitchell M Levy, Lennie Derde, Amy Dzierba, Bin Du, Flavia Machado, Hannah Wunsch, Mark Crowther, Maurizio Cecconi, Younsuck Koh, Lisa Burry, Daniel S Chertow, Wojciech Szczeklik, Emilie Belley-Cote, Massimiliano Greco, Malgorzata Bala, Ryan Zarychanski, Jozef Kesecioglu, Allison McGeer, Leonard Mermel, Manoj J Mammen, Sheila Nainan Myatra, Amy Arrington, Ruth Kleinpell, Giuseppe Citerio, Kimberley Lewis, Elizabeth Bridges, Ziad A Memish, Naomi Hammond, Frederick G Hayden, Muhammed Alshahrani, Zainab Al Duhailib, Greg S Martin, Lewis J Kaplan, Craig M Coopersmith, Massimo Antonelli, Andrew Rhodes,

<h4>Background</h4>The coronavirus disease 2019 pandemic continues to affect millions worldwide. Given the rapidly growing evidence base, we implemented a living guideline model to provide guidance on the management of patients with severe or critical coronavirus disease 2019 in the ICU.<h4>Methods</h4>The Surviving Sepsis Campaign Coronavirus Disease 2019 panel has expanded to ... Read more >>

Crit Care Med (Critical care medicine)
[2021, 49(3):e219-e234]

Cited: 37 times

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Expert consensus statements for the management of COVID-19-related acute respiratory failure using a Delphi method.

Prashant Nasa, Elie Azoulay, Ashish K Khanna, Ravi Jain, Sachin Gupta, Yash Javeri, Deven Juneja, Pradeep Rangappa, Krishnaswamy Sundararajan, Waleed Alhazzani, Massimo Antonelli, Yaseen M Arabi, Jan Bakker, Laurent J Brochard, Adam M Deane, Bin Du, Sharon Einav, Andrés Esteban, Ognjen Gajic, Samuel M Galvagno, Claude Guérin, Samir Jaber, Gopi C Khilnani, Younsuck Koh, Jean-Baptiste Lascarrou, Flavia R Machado, Manu L N G Malbrain, Jordi Mancebo, Michael T McCurdy, Brendan A McGrath, Sangeeta Mehta, Armand Mekontso-Dessap, Mervyn Mer, Michael Nurok, Pauline K Park, Paolo Pelosi, John V Peter, Jason Phua, David V Pilcher, Lise Piquilloud, Peter Schellongowski, Marcus J Schultz, Manu Shankar-Hari, Suveer Singh, Massimiliano Sorbello, Ravindranath Tiruvoipati, Andrew A Udy, Tobias Welte, Sheila N Myatra,

<h4>Background</h4>Coronavirus disease 2019 (COVID-19) pandemic has caused unprecedented pressure on healthcare system globally. Lack of high-quality evidence on the respiratory management of COVID-19-related acute respiratory failure (C-ARF) has resulted in wide variation in clinical practice.<h4>Methods</h4>Using a Delphi process, an international panel of 39 experts developed clinical practice statements on the ... Read more >>

Crit Care (Critical care (London, England))
[2021, 25(1):106]

Cited: 6 times

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Predictors of gastrointestinal bleeding in adult ICU patients in the SUP-ICU trial.

Anders Granholm, Mette Krag, Søren Marker, Waleed Alhazzani, Anders Perner, Morten Hylander Møller,

<h4>Background</h4>In previous studies of predictors of gastrointestinal (GI) bleeding in the intensive care unit (ICU), most patients received pharmacological stress ulcer prophylaxis (SUP). We aimed to assess associations between potential predictors of clinically important GI bleeding (CIB) and overt GI bleeding in adult ICU patients, while considering the effect and ... Read more >>

Acta Anaesthesiol Scand (Acta anaesthesiologica Scandinavica)
[2021, 65(6):792-800]

Cited: 0 times

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The role of eosinophils in sepsis and acute respiratory distress syndrome: a scoping review.

Zainab Al Duhailib, Malik Farooqi, Joshua Piticaru, Waleed Alhazzani, Parameswaran Nair,

<h4>Purpose</h4>Septic shock and acute respiratory distress syndrome (ARDS) are characterized by a dysregulated immune host response that may respond to steroid therapy. Eosinophils contribute to type 2 inflammation that often responds to steroid therapy; their role in immune dysregulation and outcomes in sepsis and ARDS is unclear.<h4>Source</h4>A systematic search of ... Read more >>

Can J Anaesth (Canadian journal of anaesthesia = Journal canadien d'anesthesie)
[2021, 68(5):715-726]

Cited: 1 time

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Safety and Efficacy of Dexmedetomidine in Acutely Ill Adults Requiring Noninvasive Ventilation: A Systematic Review and Meta-analysis of Randomized Trials.

Kimberley Lewis, Joshua Piticaru, Dipayan Chaudhuri, John Basmaji, Eddy Fan, Morten Hylander Møller, John W Devlin, Waleed Alhazzani,

<h4>Background</h4>Although clinical studies have evaluated dexmedetomidine as a strategy to improve noninvasive ventilation (NIV) comfort and tolerance in patients with acute respiratory failure (ARF), their results have not been summarized.<h4>Research question</h4>Does dexmedetomidine, when compared with another sedative or placebo, reduce the risk of delirium, mortality, need for intubation and mechanical ... Read more >>

Chest (Chest)
[2021, 159(6):2274-2288]

Cited: 2 times

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Convalescent Plasma in COVID-19: To what Degree should Clinicians Rely on Currently Available Data?

Waleed Alhazzani, Roman Jaeschke,

Saudi J Med Med Sci (Saudi journal of medicine & medical sciences)
[2021, 9(1):1-2]

Cited: 0 times

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The efficacy and safety of hydroxychloroquine for COVID-19 prophylaxis: A systematic review and meta-analysis of randomized trials.

Kimberley Lewis, Dipayan Chaudhuri, Fayez Alshamsi, Laiya Carayannopoulos, Karin Dearness, Zain Chagla, Waleed Alhazzani, ,

<h4>Background</h4>Populations such as healthcare workers (HCW) that are unable to practice physical distancing are at high risk of acquiring Coronavirus disease-2019 (COVID-19). In these cases pharmacological prophylaxis would be a solution to reduce severe acute respiratory syndrome coronavirus-2 (SARS CoV-2) transmission. Hydroxychloroquine has in vitro antiviral properties against SARS CoV-2. ... Read more >>

PLoS One (PloS one)
[2021, 16(1):e0244778]

Cited: 11 times

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Perspective of the Surviving Sepsis Campaign on the Management of Pediatric Sepsis in the Era of Coronavirus Disease 2019.

Scott L Weiss, Mark J Peters, Michael S D Agus, Waleed Alhazzani, Karen Choong, Heidi R Flori, David P Inwald, Simon Nadel, Mark E Nunnally, Luregn J Schlapbach, Robert C Tasker, Pierre Tissieres, Niranjan Kissoon, ,

Severe acute respiratory syndrome coronavirus 2 is a novel cause of organ dysfunction in children, presenting as either coronavirus disease 2019 with sepsis and/or respiratory failure or a hyperinflammatory shock syndrome. Clinicians must now consider these diagnoses when evaluating children for septic shock and sepsis-associated organ dysfunction. The Surviving Sepsis ... Read more >>

Pediatr Crit Care Med (Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies)
[2020, 21(11):e1031-e1037]

Cited: 7 times

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Neuromuscular blockade in patients with ARDS: a rapid practice guideline.

Waleed Alhazzani, E Belley-Cote, M H Møller, D C Angus, L Papazian, Y M Arabi, G Citerio, B Connolly, L Denehy, A Fox-Robichaud, C L Hough, J H Laake, F R Machado, M Ostermann, T Piraino, S Sharif, W Szczeklik, P J Young, A Gouskos, K Kiedrowski, K E A Burns,

The aim of this Intensive Care Medicine Rapid Practice Guideline (ICM-RPG) is to formulate an evidence-based guidance for the use of neuromuscular blocking agents (NMBA) in adults with acute respiratory distress syndrome (ARDS). The panel comprised 20 international clinical experts from 12 countries, and 2 patient representatives. We adhered to ... Read more >>

Intensive Care Med (Intensive care medicine)
[2020, 46(11):1977-1986]

Cited: 11 times

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High-Flow Nasal Cannula Treatment in Patients with COVID-19 Acute Hypoxemic Respiratory Failure

Mohammed Alshahrani, Hassan Alshaqaq, Jehan Alhumaid, Ammar Binammar, Khalid AlSalem, Abdulazez Alghamdi, Ahmed Abdulhady, Moamen Yehia, Amal AlSulaibikh, Mohammed Al Jumaan, Waleed Albuli, Talal Ibrahim, Abdullah Yousef, Yousef Almubarak, Waleed Alhazzani,

<h4>Background: </h4> The increasing burden of coronavirus disease 2019 (COVID-19)-related acute hypoxemic respiratory failure (AHRF) is straining intensive care unit (ICU) resources globally. Early use of high-flow nasal cannula (HFNC) decreases the need for endotracheal intubation (EI) in different causes of respiratory failure. While HFNC is used in COVID-19-related AHRF, ... Read more >>

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