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Genotypic Distribution and Antimicrobial Susceptibilities of Carbapenemase-Producing Enterobacteriaceae Isolated From Rectal and Clinical Samples in Korean University Hospitals Between 2016 and 2019.

Seri Jeong, Nuri Lee, Min-Jeong Park, Kibum Jeon, Han-Sung Kim, Hyun Soo Kim, Jae-Seok Kim, Wonkeun Song,

<h4>Background</h4>The emergence of carbapenemase-producing <i>Enterobacteriaceae</i> (CPE) represents a major clinical problem. Recently, the occurrence of CPE has increased globally, but epidemiological patterns vary across region. We report the trends in the genotypic distribution and antimicrobial susceptibility of CPE isolated from rectal and clinical samples during a four-year period.<h4>Methods</h4>Between January 2016 ... Read more >>

Ann Lab Med (Annals of laboratory medicine)
[2022, 42(1):36-46]

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Long noncoding RNA PP7080 promotes hepatocellular carcinoma development by sponging mir-601 and targeting SIRT1.

Weifang Song, Zhang Wenhui, Yao Ruiqiang, Xinli Hu, Ting Shi, Meijiao Wang, Haijuan Zhang,

Hepatocellular carcinoma (HCC) is the most common primary liver malignancy in adults, ranking the second leading cause of cancer-related death. To date, the underlying mechanisms of HCC pathogenesis are still unclear. Recently, more and more studies have reported that long noncoding RNAs (lncRNAs) are involved in the occurrence and development ... Read more >>

Bioengineered (Bioengineered)
[2021, 12(1):1599-1610]

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Moisture-driven changes in the sensitivity of the radial growth of Picea crassifolia to temperature, northeastern Tibetan Plateau

Wenqi Song, Changcheng Mu, Yuandong Zhang, Xu Zhang, Zongshan Li, Huiying Zhao, Xiaochun Wang,

Precipitation is one of the most important climate factors controlling tree growth, yet it is not fully understood how changes in precipitation affect the relationship between growth and temperature. On the northeastern edge of the Tibetan Plateau, nine tree-ring chronologies of Picea crassifolia were developed along a precipitation gradient from ... Read more >>

(Dendrochronologia.)
[2021, 64:Not Available]

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Inhibition of micro RNA miR-122-5p prevents lipopolysaccharide-induced myocardial injury by inhibiting oxidative stress, inflammation and apoptosis via targeting GIT1.

Wenliang Song, Tiening Zhang, Ni Yang, Tao Zhang, Ri Wen, Chunfeng Liu,

Myocardial injury resulting from sepsis is the leading cause of death worldwide. Micro RNA miR-122-5p is involved in various physiological and pathological processes and is highly expressed in the heart of septic rats. However, its function in sepsis-caused myocardial injury remains elusive. Herein, a rat model of septic myocardial injury ... Read more >>

Bioengineered (Bioengineered)
[2021, 12(1):1902-1915]

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Flavonoid biosynthetic and starch and sucrose metabolic pathways are involved in the pigmentation of naturally brown-colored cotton fibers

Zhen Peng, Qiong Gao, Cheng Luo, Wenfang Gong, Shouwu Tang, Xiaomeng Zhang, Wu Song, Zhenzhen Wang, Hailiang Liu, Xiongming Du, Haifeng Liu,

The pigment of naturally brown-colored Upland cotton fibers is caused by condensed tannin formed by the oxidation of proanthocyanidins (PAs). However, the specific roles of PA biosynthesis and glucose metabolism in brown pigmentation during fiber development are unclear. Here, proteomes and metabolomes of ovules collected at 0 days post anthesis ... Read more >>

(Industrial crops and products.)
[2021, 158:Not Available]

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The miR-1906 mimic attenuates bone loss in osteoporosis by down-regulating the TLR4/MyD88/NF-κB pathway.

H Xie, L Cao, L Ye, G Shan, W Song,

In this study, the ability of microRNA-1906 (miR-1906) to attenuate bone loss in osteoporosis was evaluated by measuring the effects of a miR-1906 mimic and inhibitor on the cellular toxicity and cell viability of MC3T3-E1 cells. Bone marrow-derived macrophage (BMM) cells were isolated from female mice, and tartrate-resistant acid phosphatase ... Read more >>

Physiol Int (Physiology international)
[2021, 107(4):469-478]

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Effects of blood pressure and heart rate circadian rhythms on left atrial function.

Yixiao Zhao, Yan Liu, Qiaobing Sun, Jiayu Han, Yushan Wei, Yan Lu, Ying Zhang, Wei Song, Yunpeng Cheng, Tao Cong, Yinong Jiang,

<h4>Objective</h4>We examined the associations among the circadian rhythms of blood pressure (BP), heart rate (HR) and left atrial function in essential hypertensive patients.<h4>Methods</h4>The study included 237 essential hypertensive patients who completed 24-h ambulatory BP, HR monitoring and two-dimensional speckle tracking echocardiography (2DSTE). The strain and strain rate images were studied, ... Read more >>

J Hypertens (Journal of hypertension)
[2021, 39(11):2318-2324]

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Low-dose metformin treatment in the subacute phase improves the locomotor function of a mouse model of spinal cord injury.

Wen-Ye Song, Han Ding, Tiffany Dunn, Jun-Ling Gao, Javier Allende Labastida, Caitlin Schlagal, Guang-Zhi Ning, Shi-Qing Feng, Ping Wu,

Metformin, a first-line drug for type-2 diabetes, has been shown to improve locomotor recovery after spinal cord injury. However, there are studies reporting no beneficial effect. Recently, we found that high dose of metformin (200 mg/kg, intraperitoneal) and acute phase administration (immediately after injury) led to increased mortality and limited ... Read more >>

Neural Regen Res (Neural regeneration research)
[2021, 16(11):2234-2242]

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Factors Associated with Partner Notification, Testing, and Positivity in HIV Partner Services Programs in the United States, 2013-2017.

Wei Song, Mesfin S Mulatu, Shubha Rao, Maria C B Mendoza, Hui Zhang Kudon, Michele Rorie,

Human immunodeficiency virus (HIV) partner services (PS) are an essential component of comprehensive HIV prevention and care. We examined factors associated with partner notification, HIV testing, and HIV positivity among partners of HIV diagnosed persons (index persons) contacted by CDC-funded state and local health departments. We analyzed PS data submitted ... Read more >>

Sex Transm Dis (Sexually transmitted diseases)
[2021, :]

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High output achieved by sliding electrification of an electrospun nano-grating.

Li-Na Zhou, Jun-Peng Wu, Wei-Zhi Song, Xiao-Xiong Wang, Ning Wang, Miao Yu, Zhi-Yong Fan, Seeram Ramakrishna, Yun-Ze Long,

The rapid development of flexible and wearable electronics has proposed a trend towards miniaturization, mobility, versatility and artificial intelligence. Triboelectric nanogenerators (TENGs) can make use of micro/nano multi-functional materials to harvest and store energy from the surrounding environment efficiently, which can drive smart portable electronics operating continuously and steadily. The ... Read more >>

Nanoscale (Nanoscale)
[2021, :]

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CVP and echo Measurements are Associated with Improved Outcomes in Patients with Gastrointestinal (GI) Hemorrhage: A Retrospective Analysis of the MIMIC- IV Database.

Wenye Song, Keyan Mobli, Daniel C Jupiter, Ravi S Radhakrishnan,

<b>Purpose:</b> Mortality associated with acute Gastrointestinal (GI) hemorrhage in intensive care units (ICU) has remained high in patients suffering from hemodynamic instability. Prompt recognition and rapid assessment of bleeding severity are crucial to improve survival. Central venous pressure (CVP) monitoring is commonly used for early recognition of intravascular imbalances, but ... Read more >>

J Intensive Care Med (Journal of intensive care medicine)
[2021, :8850666211046175]

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Correction: A randomized, open-label, parallel, multi-center Phase IV study to compare the efficacy and safety of atorvastatin 10 and 20 mg in high-risk Asian patients with hypercholesterolemia.

Ji Bak Kim, Woo Hyuk Song, Jong Sung Park, Tae-Jin Youn, Yong Hyun Park, Shin-Jae Kim, Sung Gyun Ahn, Joon-Hyung Doh, Yun-Hyeong Cho, Jin Won Kim,

[This corrects the article DOI: 10.1371/journal.pone.0245481.]. ... Read more >>

PLoS One (PloS one)
[2021, 16(10):e0259072]

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Fatigue in Patients With Multiple System Atrophy: A Prospective Cohort Study.

Lingyu Zhang, Bei Cao, Yanbing Hou, Xiaojing Gu, Qian-Qian Wei, Ruwei Ou, Bi Zhao, Wei Song, Huifang Shang,

Non-motor symptoms are common in patients with multiple system atrophy (MSA), but there is limited knowledge regarding fatigue in MSA. This study aimed to investigate the frequency and evolution of fatigue and the factors related to fatigue and its progression in patients with MSA at an early stage. Patients with ... Read more >>

Neurology (Neurology)
[2021, :]

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The Burden of Coronary Heart Disease and Cancer From Dietary Exposure To Inorganic Arsenic in Adults in China, 2016

Jialin Liu, Wenjing Song, Yiling Li, Yibaina Wang, Yuan Cui, Jiao Huang, Qi Wang, Sheng Wei,

<h4>Objective: </h4> The inorganic arsenic (iAs) could cause a wide range of health damage, including coronary heart disease (CHD) and lung, bladder, and skin cancer. Although dietary iAs intake is the primary source of iAs, the burden of CHD and cancers from dietary iAs exposure in Chinese adults has not ... Read more >>

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Codelivery of High-Molecular-Weight Poly-porphyrins and HIF-1α Inhibitors for In Vivo Synergistic Anticancer Therapy.

Junnan He, Kangkai Xia, Binggong Zhao, Wangze Song, Yubin Zheng, Guishan Xiao, Huijian Wu, Nan Zheng,

Photodynamic therapy (PDT) is showing great potential in the treatment of cancer diseases, and photosensitizers play crucial roles in absorbing the energy of light and generating reactive oxygen species (ROS) during PDT. Most of the photosensitizers bearing macrocyclic structures have strong hydrophobicity and suffer from the π-π interaction and undesired ... Read more >>

Biomacromolecules (Biomacromolecules)
[2021, :]

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LncRNA-URHC Functions as ceRNA to Regulate DNAJB9 Expression by Competitively Binding to miR-5007-3p in Hepatocellular Carcinoma.

Kunwei Niu, Shibin Qu, Xuan Zhang, Jimin Dai, Jianlin Wang, Ye Nie, Hong Zhang, Kaishan Tao, Wenjie Song,

Hepatocellular carcinoma (HCC) is often diagnosed at a late stage, when the prognosis is poor. The regulation of long noncoding RNAs (lncRNAs) plays a crucial role in HCC. However, the precise regulatory mechanisms of lncRNA signaling in HCC remain largely unknown. Our study aims to investigate the underlying mechanisms of ... Read more >>

Evid Based Complement Alternat Med (Evidence-based complementary and alternative medicine : eCAM)
[2021, 2021:3031482]

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Echogenicity of Dupuytren's nodules is correlated to myofibroblast load and nodule hardness.

Sanne Molenkamp, Whangzao Song, Marjolein Bloembergen, Dieuwke C Broekstra, Paul M N Werker,

This study aimed to determine the association between the echogenicity of Dupuytren's disease nodules and myofibroblast load, and between echogenicity and nodule hardness. Thirty-eight nodules were assessed sonographically. The echogenicity of nodules was measured objectively with Image J (grey-value) and subjectively by visual inspection (hypo-, mixed and hyper-echogenicity). These findings ... Read more >>

J Hand Surg Eur Vol (The Journal of hand surgery, European volume)
[2021, :17531934211050214]

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Propranolol inhibits the angiogenic capacity of hemangioma endothelia via blocking β-adrenoceptor in mast cell.

Ying Ye, Huaqing Zhong, Limin Dou, Wei Song, Chenbin Dong, Wenmin Lu, Kuiran Dong, Kai Li, Jun Li, Lingfeng He, Wei Gao, Chunmei Xia, Liuhui Wang,

<h4>Background</h4>Propranolol, a non-selective blocker of the β-adrenoceptor (AR), is a first-line treatment for infantile hemangioma (IH). Mast cells have been implicated in the pathophysiology of propranolol-treated hemangioma. However, the function of mast cells remains unclear.<h4>Methods</h4>HMC-1s (Human mast cell line) having been treated with propranolol for 24 h were centrifuged, washed with ... Read more >>

Pediatr Res (Pediatric research)
[2021, :]

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N-glycosylation of a cargo protein C-terminal domain recognized by the type IX secretion system in Cytophaga hutchinsonii affects protein secretion and localization.

Shuaishuai Xie, Yahong Tan, Wenxia Song, Weican Zhang, Qingsheng Qi, Xuemei Lu,

<i>Cytophaga hutchinsonii</i> is a Gram-negative bacterium belonging to the phylum <i>Bacteroidetes</i>. It digests crystalline cellulose with an unknown mechanism, and possesses a type IX secretion system (T9SS) that can recognize the C-terminal domain (CTD) of the cargo protein as a signal. In this study, the functions of CTD in the ... Read more >>

Appl Environ Microbiol (Applied and environmental microbiology)
[2021, :AEM0160621]

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Subtype-WESLR: identifying cancer subtype with weighted ensemble sparse latent representation of multi-view data.

Wenjing Song, Weiwen Wang, Dao-Qing Dai,

The discovery of cancer subtypes has become much-researched topic in oncology. Dividing cancer patients into subtypes can provide personalized treatments for heterogeneous patients. High-throughput technologies provide multiple omics data for cancer subtyping. Integration of multi-view data is used to identify cancer subtypes in many computational methods, which obtain different subtypes ... Read more >>

Brief Bioinform (Briefings in bioinformatics)
[2021, :]

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Fluorescent paper strip immunoassay with carbon [email protected] for determination of human serum amyloid A1.

Mulya Supianto, Sang Hyuk Lee, Sung Hwa Jhung, Hazara Begum Mohammad, Hung M Vu, Min-Sik Kim, Woo-Young Song, Tae-Young Kim, Hye Jin Lee,

A fluorescent paper strip immunoassay in conjunction with carbon [email protected] ([email protected]) as a label was developed for the quantitative measurements of human serum amyloid A1 (hSAA1) in serum at clinically significant concentrations for lung cancer diagnosis. Monodispersed [email protected] was prepared by cohydrolysis between silane-crosslinked carbon nanodots and silica precursors via ... Read more >>

Mikrochim Acta (Mikrochimica acta)
[2021, 188(11):386]

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An invasive species erodes the performance of coastal wetland protected areas.

Junlin Ren, Jianshe Chen, Changlin Xu, Johan van de Koppel, Mads S Thomsen, Shiyun Qiu, Fangyan Cheng, Wanjuan Song, Quan-Xing Liu, Chi Xu, Junhong Bai, Yihui Zhang, Baoshan Cui, Mark D Bertness, Brian R Silliman, Bo Li, Qiang He,

[Figure: see text]. ... Read more >>

Sci Adv (Science advances)
[2021, 7(42):eabi8943]

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A single-cell interactome of human tooth germ from growing third molar elucidates signaling networks regulating dental development.

Yueqi Shi, Yejia Yu, Yuqiong Zhou, Jun Zhao, Wenjie Zhang, Duohong Zou, Weichen Song, Shaoyi Wang,

<h4>Background</h4>Development of dental tissue is regulated by extensive cell crosstalk based on various signaling molecules, such as bone morphogenetic protein (BMP) and fibroblast growth factor (FGF) pathways. However, an intact network of the intercellular regulation is still lacking.<h4>Result</h4>To gain an unbiased and comprehensive view of this dental cell interactome, we ... Read more >>

Cell Biosci (Cell & bioscience)
[2021, 11(1):178]

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Corrigendum: Short-Interval Sequential CAR-T Cell Infusion May Enhance Prior CAR-T Cell Expansion to Augment Anti-Lymphoma Response in B-NHL.

Yuan Meng, Biping Deng, Luan Rong, Chuo Li, Weiliang Song, Zhuojun Ling, Jinlong Xu, Jiajia Duan, Zelin Wang, Alex H Chang, Xiaoming Feng, Xiujuan Xiong, Xiaoli Chen, Jing Pan,

[This corrects the article DOI: 10.3389/fonc.2021.640166.]. ... Read more >>

Front Oncol (Frontiers in oncology)
[2021, 11:778039]

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Bioaugmentation with syntrophic volatile fatty acids-oxidizing consortia to alleviate the ammonia inhibition in continuously anaerobic digestion of municipal sludge.

Mao-Ting Li, Ling Rao, Lu Wang, Min Gou, Zhao-Yong Sun, Zi-Yuan Xia, Wen-Feng Song, Yue-Qin Tang,

Ammonia inhibition easily affects the performance of anaerobic digestion (AD) for municipal sludge and the oxidization of volatile fatty acids (VFAs) is the rate-limiting step of this process. Bioaugmentation is considered to be an effective method to alleviate ammonia inhibition of AD, but most study used the hydrogenotrophic methanogens as ... Read more >>

Chemosphere (Chemosphere)
[2021, 288(Pt 2):132389]

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