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Author W M Monique Verschuren

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Pain over the adult life course: 15-year pain trajectories-The Doetinchem Cohort Study.

H Susan J Picavet, W M Monique Verschuren, Lichelle Groot, Laura Schaap, Sandra H van Oostrom,

BACKGROUND:Pain at any age is related to pain experienced at younger ages, but not much is known on how pain develops over the adult life course. We studied long-term individual trajectories of pain over 15 years of the life course and evaluated the role of baseline sociodemographic factors, lifestyle factors and ... Read more >>

Eur J Pain (European journal of pain (London, England))
[2019, :]

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Frailty is associated with elevated CRP trajectories and higher numbers of neutrophils and monocytes.

Leonard Daniël Samson, A Mieke H Boots, W M Monique Verschuren, H Susan J Picavet, Peter Engelfriet, Anne-Marie Buisman,

BACKGROUND:With aging, the human immune system undergoes several changes. The clinical relevance of these changes, however, is relatively unknown. We investigated immunological aspects of human aging in relation to frailty in the Doetinchem Cohort Study (DCS). METHODS:We calculated a frailty index score based on 36 health parameters for each individual ... Read more >>

Exp. Gerontol. (Experimental gerontology)
[2019, 125:110674]

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Trajectories of (Bio)markers During the Development of Cognitive Frailty in the Doetinchem Cohort Study.

M Liset Rietman, Gerben Hulsegge, Astrid C J Nooyens, Martijn E T Dollé, H Susan J Picavet, Stephan J L Bakker, Ron T Gansevoort, Annemieke M W Spijkerman, W M Monique Verschuren,

Background: Long-term changes in (bio)markers for cognitive frailty are not well characterized. Therefore, our aim is to explore (bio)marker trajectories in adults who became cognitively frail compared to age- and sex-matched controls who did not become cognitively frail over a 15 year follow-up. We hypothesize that those who become cognitively ... Read more >>

Front Neurol (Frontiers in neurology)
[2019, 10:497]

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Risk for Heart Failure: The Opportunity for Prevention With the American Heart Association's Life's Simple 7.

Alicia Uijl, Stefan Koudstaal, Ilonca Vaartjes, Jolanda M A Boer, W M Monique Verschuren, Yvonne T van der Schouw, Folkert W Asselbergs, Arno W Hoes, Ivonne Sluijs,

OBJECTIVES:The aim of this study is to determine whether combinations of specific Life's Simple 7 (LS7) components are associated with reduced risk for heart failure (HF). BACKGROUND:The American Heart Association recommends the concept of LS7: healthy behaviors that have been shown to reduce cardiovascular disease. METHODS:A total of 37,803 participants ... Read more >>

JACC Heart Fail (JACC. Heart failure)
[2019, 7(8):637-647]

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Top 10 Research Priorities in Spatial Lifecourse Epidemiology.

Peng Jia, Jeroen Lakerveld, Jianguo Wu, Alfred Stein, Elisabeth D Root, Clive E Sabel, Roel Vermeulen, Justin V Remais, Xi Chen, Ross C Brownson, Sherif Amer, Qian Xiao, Limin Wang, W M Monique Verschuren, Tong Wu, Youfa Wang, Peter James,

The International Initiative on Spatial Lifecourse Epidemiology (ISLE) convened its first International Symposium on Lifecourse Epidemiology and Spatial Science at the Lorentz Center in Leiden, Netherlands, 16–20 July 2018. Its aim was to further an emerging transdisciplinary field: Spatial Lifecourse Epidemiology. This field draws from a broad perspective of scientific ... Read more >>

Environ. Health Perspect. (Environmental health perspectives)
[2019, 127(7):74501]

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Prediction of individualized lifetime benefit from cholesterol lowering, blood pressure lowering, antithrombotic therapy, and smoking cessation in apparently healthy people.

Nicole E M Jaspers, Michael J Blaha, Kunihiro Matsushita, Yvonne T van der Schouw, Nicholas J Wareham, Kay-Tee Khaw, Marie H Geisel, Nils Lehmann, Raimund Erbel, Karl-Heinz Jöckel, Yolanda van der Graaf, W M Monique Verschuren, Jolanda M A Boer, Vijay Nambi, Frank L J Visseren, Jannick A N Dorresteijn,

AIMS:The benefit an individual can expect from preventive therapy varies based on risk-factor burden, competing risks, and treatment duration. We developed and validated the LIFEtime-perspective CardioVascular Disease (LIFE-CVD) model for the estimation of individual-level 10 years and lifetime treatment-effects of cholesterol lowering, blood pressure lowering, antithrombotic therapy, and smoking cessation ... Read more >>

Eur. Heart J. (European heart journal)
[2019, :]

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Consumption of Meat, Fish, Dairy Products, and Eggs and Risk of Ischemic Heart Disease.

Timothy J Key, Paul N Appleby, Kathryn E Bradbury, Michael Sweeting, Angela Wood, Ingegerd Johansson, Tilman Kühn, Marinka Steur, Elisabete Weiderpass, Maria Wennberg, Anne Mette Lund Würtz, Antonio Agudo, Jonas Andersson, Larraitz Arriola, Heiner Boeing, Jolanda M A Boer, Fabrice Bonnet, Marie-Christine Boutron-Ruault, Amanda J Cross, Ulrika Ericson, Guy Fagherazzi, Pietro Ferrari, Marc Gunter, José María Huerta, Verena Katzke, Kay-Tee Khaw, Vittorio Krogh, Carlo La Vecchia, Giuseppe Matullo, Conchi Moreno-Iribas, Androniki Naska, Lena Maria Nilsson, Anja Olsen, Kim Overvad, Domenico Palli, Salvatore Panico, Elena Molina-Portillo, J Ramón Quirós, Guri Skeie, Ivonne Sluijs, Emily Sonestedt, Magdalena Stepien, Anne Tjønneland, Antonia Trichopoulou, Rosario Tumino, Ioanna Tzoulaki, Yvonne T van der Schouw, W M Monique Verschuren, Emanuele di Angelantonio, Claudia Langenberg, Nita Forouhi, Nick Wareham, Adam Butterworth, Elio Riboli, John Danesh,

BACKGROUND:There is uncertainty about the relevance of animal foods to the pathogenesis of ischemic heart disease (IHD). We examined meat, fish, dairy products, and eggs and risk for IHD in the pan-European EPIC cohort (European Prospective Investigation Into Cancer and Nutrition). METHODS:In this prospective study of 409 885 men and women ... Read more >>

Circulation (Circulation)
[2019, 139(25):2835-2845]

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Do generations differ in sports participation and physical activity over the life course? Evidence from multiple datasets.

Sandra H van Oostrom, Lany C J Slobbe, Saskia W van den Berg, W M Monique Verschuren, H Susan J Picavet,

Generational differences in health-related factors will affect forecasts of future disease patterns and health care needs. We studied whether participation in sports activity and being physically active are different between 10-year generations over a part of their life course. We used three different datasets on Dutch adults: a cohort study ... Read more >>

Eur J Sport Sci (European journal of sport science)
[2019, :1-9]

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Rising rural body-mass index is the main driver of the global obesity epidemic in adults.

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Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities1,2. This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity3-6. Here we use ... Read more >>

Nature (Nature)
[2019, 569(7755):260-264]

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Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality.

Matti Marklund, Jason H Y Wu, Fumiaki Imamura, Liana C Del Gobbo, Amanda Fretts, Janette de Goede, Peilin Shi, Nathan Tintle, Maria Wennberg, Stella Aslibekyan, Tzu-An Chen, Marcia C de Oliveira Otto, Yoichiro Hirakawa, Helle Højmark Eriksen, Janine Kröger, Federica Laguzzi, Maria Lankinen, Rachel A Murphy, Kiesha Prem, Cécilia Samieri, Jyrki Virtanen, Alexis C Wood, Kerry Wong, Wei-Sin Yang, Xia Zhou, Ana Baylin, Jolanda M A Boer, Ingeborg A Brouwer, Hannia Campos, Paulo H M Chaves, Kuo-Liong Chien, Ulf de Faire, Luc Djoussé, Gudny Eiriksdottir, Naglaa El-Abbadi, Nita G Forouhi, J Michael Gaziano, Johanna M Geleijnse, Bruna Gigante, Graham Giles, Eliseo Guallar, Vilmundur Gudnason, Tamara Harris, William S Harris, Catherine Helmer, Mai-Lis Hellenius, Allison Hodge, Frank B Hu, Paul F Jacques, Jan-Håkan Jansson, Anya Kalsbeek, Kay-Tee Khaw, Woon-Puay Koh, Markku Laakso, Karin Leander, Hung-Ju Lin, Lars Lind, Robert Luben, Juhua Luo, Barbara McKnight, Jaakko Mursu, Toshiharu Ninomiya, Kim Overvad, Bruce M Psaty, Eric Rimm, Matthias B Schulze, David Siscovick, Michael Skjelbo Nielsen, Albert V Smith, Brian T Steffen, Lyn Steffen, Qi Sun, Johan Sundström, Michael Y Tsai, Hugh Tunstall-Pedoe, Matti I J Uusitupa, Rob M van Dam, Jenna Veenstra, W M Monique Verschuren, Nick Wareham, Walter Willett, Mark Woodward, Jian-Min Yuan, Renata Micha, Rozenn N Lemaitre, Dariush Mozaffarian, Ulf Risérus, ,

BACKGROUND:Global dietary recommendations for and cardiovascular effects of linoleic acid, the major dietary omega-6 fatty acid, and its major metabolite, arachidonic acid, remain controversial. To address this uncertainty and inform international recommendations, we evaluated how in vivo circulating and tissue levels of linoleic acid (LA) and arachidonic acid (AA) relate ... Read more >>

Circulation (Circulation)
[2019, 139(21):2422-2436]

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Association of menopausal characteristics and risk of coronary heart disease: a pan-European case-cohort analysis.

Veerle Dam, Yvonne T van der Schouw, N Charlotte Onland-Moret, Rolf H H Groenwold, Sanne A E Peters, Stephen Burgess, Angela M Wood, Maria-Dolores Chirlaque, Karel G M Moons, Clare Oliver-Williams, Ewoud Schuit, Kaja Tikk, Elisabete Weiderpass, Marianne Holm, Anne Tjønneland, Tilman Kühn, Renée T Fortner, Antonia Trichopoulou, Anna Karakatsani, Carlo La Vecchia, Pietro Ferrari, Marc Gunter, Giovanna Masala, Sabina Sieri, Rosario Tumino, Salvatore Panico, Jolanda M A Boer, W M Monique Verschuren, Elena Salamanca-Fernández, Larraitz Arriola, Conchi Moreno-Iribas, Gunnar Engström, Olle Melander, Maria Nordendahl, Patrik Wennberg, Timothy J Key, Sandra Colorado-Yohar, Giuseppe Matullo, Kim Overvad, Francoise Clavel-Chapelon, Heiner Boeing, J Ramon Quiros, Emanuele di Angelantonio, Claudia Langenberg, Michael J Sweeting, Elio Riboli, Nicholas J Wareham, John Danesh, Adam Butterworth,

BACKGROUND:Earlier age at menopause has been associated with increased risk of coronary heart disease (CHD), but the shape of association and role of established cardiovascular risk factors remain unclear. Therefore, we examined the associations between menopausal characteristics and CHD risk; the shape of the association between age at menopause and ... Read more >>

Int J Epidemiol (International journal of epidemiology)
[2019, :]

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Substitutions between dairy products and risk of stroke: results from the European Investigation into Cancer and Nutrition-Netherlands (EPIC-NL) cohort.

Anne Sofie D Laursen, Ivonne Sluijs, Jolanda M A Boer, W M Monique Verschuren, Yvonne T van der Schouw, Marianne U Jakobsen,

The association between intake of different dairy products and the risk of stroke remains unclear. We therefore investigated substitutions between dairy product subgroups and risk of stroke. We included 36 886 Dutch men and women. Information about dairy product intake was collected through a FFQ. Dairy products were grouped as ... Read more >>

Br. J. Nutr. (The British journal of nutrition)
[2019, 121(12):1398-1404]

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Equalization of four cardiovascular risk algorithms after systematic recalibration: individual-participant meta-analysis of 86 prospective studies.

Lisa Pennells, Stephen Kaptoge, Angela Wood, Mike Sweeting, Xiaohui Zhao, Ian White, Stephen Burgess, Peter Willeit, Thomas Bolton, Karel G M Moons, Yvonne T van der Schouw, Randi Selmer, Kay-Tee Khaw, Vilmundur Gudnason, Gerd Assmann, Philippe Amouyel, Veikko Salomaa, Mika Kivimaki, Børge G Nordestgaard, Michael J Blaha, Lewis H Kuller, Hermann Brenner, Richard F Gillum, Christa Meisinger, Ian Ford, Matthew W Knuiman, Annika Rosengren, Debbie A Lawlor, Henry Völzke, Cyrus Cooper, Alejandro Marín Ibañez, Edoardo Casiglia, Jussi Kauhanen, Jackie A Cooper, Beatriz Rodriguez, Johan Sundström, Elizabeth Barrett-Connor, Rachel Dankner, Paul J Nietert, Karina W Davidson, Robert B Wallace, Dan G Blazer, Cecilia Björkelund, Chiara Donfrancesco, Harlan M Krumholz, Aulikki Nissinen, Barry R Davis, Sean Coady, Peter H Whincup, Torben Jørgensen, Pierre Ducimetiere, Maurizio Trevisan, Gunnar Engström, Carlos J Crespo, Tom W Meade, Marjolein Visser, Daan Kromhout, Stefan Kiechl, Makoto Daimon, Jackie F Price, Agustin Gómez de la Cámara, J Wouter Jukema, Benoît Lamarche, Altan Onat, Leon A Simons, Maryam Kavousi, Yoav Ben-Shlomo, John Gallacher, Jacqueline M Dekker, Hisatomi Arima, Nawar Shara, Robert W Tipping, Ronan Roussel, Eric J Brunner, Wolfgang Koenig, Masaru Sakurai, Jelena Pavlovic, Ron T Gansevoort, Dorothea Nagel, Uri Goldbourt, Elizabeth L M Barr, Luigi Palmieri, Inger Njølstad, Shinichi Sato, W M Monique Verschuren, Cherian V Varghese, Ian Graham, Oyere Onuma, Philip Greenland, Mark Woodward, Majid Ezzati, Bruce M Psaty, Naveed Sattar, Rod Jackson, Paul M Ridker, Nancy R Cook, Ralph B D'Agostino, Simon G Thompson, John Danesh, Emanuele Di Angelantonio, ,

AIMS:There is debate about the optimum algorithm for cardiovascular disease (CVD) risk estimation. We conducted head-to-head comparisons of four algorithms recommended by primary prevention guidelines, before and after 'recalibration', a method that adapts risk algorithms to take account of differences in the risk characteristics of the populations being studied. METHODS ... Read more >>

Eur. Heart J. (European heart journal)
[2019, 40(7):621-631]

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Cardiovascular Risk Factors Associated With Venous Thromboembolism.

John Gregson, Stephen Kaptoge, Thomas Bolton, Lisa Pennells, Peter Willeit, Stephen Burgess, Steven Bell, Michael Sweeting, Eric B Rimm, Christopher Kabrhel, Bengt Zöller, Gerd Assmann, Vilmundur Gudnason, Aaron R Folsom, Volker Arndt, Astrid Fletcher, Paul E Norman, Børge G Nordestgaard, Akihiko Kitamura, Bakhtawar K Mahmoodi, Peter H Whincup, Matthew Knuiman, Veikko Salomaa, Christa Meisinger, Wolfgang Koenig, Maryam Kavousi, Henry Völzke, Jackie A Cooper, Toshiharu Ninomiya, Edoardo Casiglia, Beatriz Rodriguez, Yoav Ben-Shlomo, Jean-Pierre Després, Leon Simons, Elizabeth Barrett-Connor, Cecilia Björkelund, Marlene Notdurfter, Daan Kromhout, Jackie Price, Susan E Sutherland, Johan Sundström, Jussi Kauhanen, John Gallacher, Joline W J Beulens, Rachel Dankner, Cyrus Cooper, Simona Giampaoli, Jason F Deen, Agustín Gómez de la Cámara, Lewis H Kuller, Annika Rosengren, Peter J Svensson, Dorothea Nagel, Carlos J Crespo, Hermann Brenner, Juan R Albertorio-Diaz, Robert Atkins, Eric J Brunner, Martin Shipley, Inger Njølstad, Deborah A Lawlor, Yvonne T van der Schouw, Randi Marie Selmer, Maurizio Trevisan, W M Monique Verschuren, Philip Greenland, Sylvia Wassertheil-Smoller, Gordon D O Lowe, Angela M Wood, Adam S Butterworth, Simon G Thompson, John Danesh, Emanuele Di Angelantonio, Tom Meade, ,

Importance:It is uncertain to what extent established cardiovascular risk factors are associated with venous thromboembolism (VTE). Objective:To estimate the associations of major cardiovascular risk factors with VTE, ie, deep vein thrombosis and pulmonary embolism. Design, Setting, and Participants:This study included individual participant data mostly from essentially population-based cohort studies from ... Read more >>

JAMA Cardiol (JAMA cardiology)
[2019, 4(2):163-173]

Cited: 1 time

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Separate and combined associations of obesity and metabolic health with coronary heart disease: a pan-European case-cohort analysis.

Camille Lassale, Ioanna Tzoulaki, Karel G M Moons, Michael Sweeting, Jolanda Boer, Laura Johnson, José María Huerta, Claudia Agnoli, Heinz Freisling, Elisabete Weiderpass, Patrik Wennberg, Daphne L van der A, Larraitz Arriola, Vassiliki Benetou, Heiner Boeing, Fabrice Bonnet, Sandra M Colorado-Yohar, Gunnar Engström, Anne K Eriksen, Pietro Ferrari, Sara Grioni, Matthias Johansson, Rudolf Kaaks, Michail Katsoulis, Verena Katzke, Timothy J Key, Giuseppe Matullo, Olle Melander, Elena Molina-Portillo, Concepción Moreno-Iribas, Margareta Norberg, Kim Overvad, Salvatore Panico, J Ramón Quirós, Calogero Saieva, Guri Skeie, Annika Steffen, Magdalena Stepien, Anne Tjønneland, Antonia Trichopoulou, Rosario Tumino, Yvonne T van der Schouw, W M Monique Verschuren, Claudia Langenberg, Emanuele Di Angelantonio, Elio Riboli, Nicholas J Wareham, John Danesh, Adam S Butterworth,

Aims:The hypothesis of 'metabolically healthy obesity' implies that, in the absence of metabolic dysfunction, individuals with excess adiposity are not at greater cardiovascular risk. We tested this hypothesis in a large pan-European prospective study. Methods and results:We conducted a case-cohort analysis in the 520 000-person European Prospective Investigation into Cancer and ... Read more >>

Eur. Heart J. (European heart journal)
[2018, 39(5):397-406]

Cited: 23 times

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Shift work, chronotype and the risk of cardiometabolic risk factors.

Gerben Hulsegge, H Susan J Picavet, Allard J van der Beek, W M Monique Verschuren, Jos W Twisk, Karin I Proper,

Background:The relation between shift work and a large variety of cardiometabolic risk factors is unclear. Also, the role of chronotype is understudied. We examined relations between shift work and cardiometabolic risk factors, and explored these relations in different chronotypes. Methods:Cardiometabolic risk factors (anthropometry, blood pressure, lipids, diabetes, γ-glutamyltransferase, C-reactive protein, ... Read more >>

Eur J Public Health (European journal of public health)
[2019, 29(1):128-134]

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Pure fruit juice and fruit consumption and the risk of CVD: the European Prospective Investigation into Cancer and Nutrition-Netherlands (EPIC-NL) study.

Floor R Scheffers, Jolanda M A Boer, W M Monique Verschuren, Martijn Verheus, Yvonne T van der Schouw, Ivonne Sluijs, Henriëtte A Smit, Alet H Wijga,

Dietary guidelines for pure fruit juice consumption differ between countries, regarding the question whether pure fruit juice is an acceptable alternative for fruit. Currently, little is known about pure fruit juice consumption and the risk of CVD. In this prospective cohort study, we studied the association of pure fruit juice ... Read more >>

Br. J. Nutr. (The British journal of nutrition)
[2019, 121(3):351-359]

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Fatty acids from dairy and meat and their association with risk of coronary heart disease.

Linda E T Vissers, Jonna Rijksen, Jolanda M A Boer, W M Monique Verschuren, Yvonne T van der Schouw, Ivonne Sluijs,

The relationship of total, saturated, mono-unsaturated and poly-unsaturated fatty acids (SFA, MUFA, PUFA) with coronary heart disease (CHD) is debated. We hypothesized that the association of dairy-derived FA with CHD may be different than the association of meat-derived FA with CHD. We therefore aimed to directly compare association of FA ... Read more >>

Eur J Nutr (European journal of nutrition)
[2018, :]

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Cardiovascular risk model performance in women with and without hypertensive disorders of pregnancy.

Veerle Dam, N Charlotte Onland-Moret, W M Monique Verschuren, Jolanda M A Boer, Laura Benschop, Arie Franx, Karel G M Moons, Eric Boersma, Yvonne T van der Schouw, ,

Compare the predictive performance of Framingham Risk Score (FRS), Pooled Cohort Equations (PCEs) and Systematic COronary Risk Evaluation (SCORE) model between women with and without a history of hypertensive disorders of pregnancy (hHDP) and determine the effects of recalibration and refitting on predictive performance.We included 29 751 women, 6302 with hHDP ... Read more >>

Heart (Heart (British Cardiac Society))
[2018, :]

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Alcohol intake in relation to non-fatal and fatal coronary heart disease and stroke: EPIC-CVD case-cohort study.

Cristian Ricci, Angela Wood, David Muller, Marc J Gunter, Antonio Agudo, Heiner Boeing, Yvonne T van der Schouw, Samantha Warnakula, Calogero Saieva, Annemieke Spijkerman, Ivonne Sluijs, Anne Tjønneland, Cecilie Kyrø, Elisabete Weiderpass, Tilman Kühn, Rudolf Kaaks, Maria-Jose Sánchez, Salvatore Panico, Claudia Agnoli, Domenico Palli, Rosario Tumino, Gunnar Engström, Olle Melander, Fabrice Bonnet, Jolanda M A Boer, Timothy J Key, Ruth C Travis, Kim Overvad, W M Monique Verschuren, J Ramón Quirós, Antonia Trichopoulou, Eleni-Maria Papatesta, Eleni Peppa, Conchi Moreno Iribas, Diana Gavrila, Ann-Sofie Forslund, Jan-Håkan Jansson, Giuseppe Matullo, Larraitz Arriola, Heinz Freisling, Camille Lassale, Ioanna Tzoulaki, Stephen J Sharp, Nita G Forouhi, Claudia Langenberg, Rodolfo Saracci, Michael Sweeting, Paul Brennan, Adam S Butterworth, Elio Riboli, Nick J Wareham, John Danesh, Pietro Ferrari,

OBJECTIVE:To investigate the association between alcohol consumption (at baseline and over lifetime) and non-fatal and fatal coronary heart disease (CHD) and stroke. DESIGN:Multicentre case-cohort study. SETTING:A study of cardiovascular disease (CVD) determinants within the European Prospective Investigation into Cancer and nutrition cohort (EPIC-CVD) from eight European countries. PARTICIPANTS:32 549 participants without ... Read more >>

BMJ (BMJ (Clinical research ed.))
[2018, 361:k934]

Cited: 4 times

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Aging-related trajectories of lung function in the general population-The Doetinchem Cohort Study.

Sandra H van Oostrom, Peter M Engelfriet, W M Monique Verschuren, Maarten Schipper, Inge M Wouters, Marike Boezen, Henriëtte A Smit, Huib A M Kerstjens, H Susan J Picavet,

The objective of this study was to explore trajectories of lung function decline with age in the general population, and to study the effect of sociodemographic and life style related risk factors, in particular smoking and BMI. For this purpose, we used data from the Doetinchem Cohort Study (DCS) of ... Read more >>

PLoS ONE (PloS one)
[2018, 13(5):e0197250]

Cited: 1 time

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Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: a pooled analysis of 1018 population-based measurement studies with 88.6 million participants.

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Background:Change in the prevalence of raised blood pressure could be due to both shifts in the entire distribution of blood pressure (representing the combined effects of public health interventions and secular trends) and changes in its high-blood-pressure tail (representing successful clinical interventions to control blood pressure in the hypertensive population). ... Read more >>

Int J Epidemiol (International journal of epidemiology)
[2018, :]

Cited: 2 times

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Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies.

Angela M Wood, Stephen Kaptoge, Adam S Butterworth, Peter Willeit, Samantha Warnakula, Thomas Bolton, Ellie Paige, Dirk S Paul, Michael Sweeting, Stephen Burgess, Steven Bell, William Astle, David Stevens, Albert Koulman, Randi M Selmer, W M Monique Verschuren, Shinichi Sato, Inger Njølstad, Mark Woodward, Veikko Salomaa, Børge G Nordestgaard, Bu B Yeap, Astrid Fletcher, Olle Melander, Lewis H Kuller, Beverley Balkau, Michael Marmot, Wolfgang Koenig, Edoardo Casiglia, Cyrus Cooper, Volker Arndt, Oscar H Franco, Patrik Wennberg, John Gallacher, Agustín Gómez de la Cámara, Henry Völzke, Christina C Dahm, Caroline E Dale, Manuela M Bergmann, Carlos J Crespo, Yvonne T van der Schouw, Rudolf Kaaks, Leon A Simons, Pagona Lagiou, Josje D Schoufour, Jolanda M A Boer, Timothy J Key, Beatriz Rodriguez, Conchi Moreno-Iribas, Karina W Davidson, James O Taylor, Carlotta Sacerdote, Robert B Wallace, J Ramon Quiros, Rosario Tumino, Dan G Blazer, Allan Linneberg, Makoto Daimon, Salvatore Panico, Barbara Howard, Guri Skeie, Timo Strandberg, Elisabete Weiderpass, Paul J Nietert, Bruce M Psaty, Daan Kromhout, Elena Salamanca-Fernandez, Stefan Kiechl, Harlan M Krumholz, Sara Grioni, Domenico Palli, José M Huerta, Jackie Price, Johan Sundström, Larraitz Arriola, Hisatomi Arima, Ruth C Travis, Demosthenes B Panagiotakos, Anna Karakatsani, Antonia Trichopoulou, Tilman Kühn, Diederick E Grobbee, Elizabeth Barrett-Connor, Natasja van Schoor, Heiner Boeing, Kim Overvad, Jussi Kauhanen, Nick Wareham, Claudia Langenberg, Nita Forouhi, Maria Wennberg, Jean-Pierre Després, Mary Cushman, Jackie A Cooper, Carlos J Rodriguez, Masaru Sakurai, Jonathan E Shaw, Matthew Knuiman, Trudy Voortman, Christa Meisinger, Anne Tjønneland, Hermann Brenner, Luigi Palmieri, Jean Dallongeville, Eric J Brunner, Gerd Assmann, Maurizio Trevisan, Richard F Gillum, Ian Ford, Naveed Sattar, Mariana Lazo, Simon G Thompson, Pietro Ferrari, David A Leon, George Davey Smith, Richard Peto, Rod Jackson, Emily Banks, Emanuele Di Angelantonio, John Danesh, ,

BACKGROUND:Low-risk limits recommended for alcohol consumption vary substantially across different national guidelines. To define thresholds associated with lowest risk for all-cause mortality and cardiovascular disease, we studied individual-participant data from 599 912 current drinkers without previous cardiovascular disease. METHODS:We did a combined analysis of individual-participant data from three large-scale data sources ... Read more >>

Lancet (Lancet (London, England))
[2018, 391(10129):1513-1523]

Cited: 50 times

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Antioxidants linked with physical, cognitive and psychological frailty: Analysis of candidate biomarkers and markers derived from the MARK-AGE study.

M Liset Rietman, Annemieke M W Spijkerman, Albert Wong, Harry van Steeg, Alexander Bürkle, María Moreno-Villanueva, Thilo Sindlinger, Claudio Franceschi, Beatrix Grubeck-Loebenstein, Jürgen Bernhardt, P Eline Slagboom, Olivier Toussaint, Florence Debacq-Chainiaux, Ewa Sikora, Efstathios S Gonos, Nicolle Breusing, Wolfgang Stuetz, Daniela Weber, Tilman Grune, Andrea Basso, Francesco Piacenza, Marco Malavolta, Sebastiano Collino, Eugene H J M Jansen, W M Monique Verschuren, Martijn E T Dollé,

Frailty among elderly people leads to an increased risk for negative health outcomes. To prevent frailty, we need a better understanding of the underlying mechanisms and early detection of individuals at risk. Both may be served by identifying candidate (bio)markers, i.e. biomarkers and markers, for the physical, cognitive, and psychological ... Read more >>

Mech. Ageing Dev. (Mechanisms of ageing and development)
[2019, 177:135-143]

Cited: 2 times

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Health literacy among older adults is associated with their 10-years' cognitive functioning and decline - the Doetinchem Cohort Study.

Bas Geboers, Ellen Uiters, Sijmen A Reijneveld, Carel J M Jansen, Josué Almansa, Astrid C J Nooyens, W M Monique Verschuren, Andrea F de Winter, H Susan J Picavet,

Many older adults have low levels of health literacy which affects their ability to participate optimally in healthcare. It is unclear how cognitive decline contributes to health literacy. To study this, longitudinal data are needed. The aim of this study was therefore to assess the associations of cognitive functioning and ... Read more >>

BMC Geriatr (BMC geriatrics)
[2018, 18(1):77]

Cited: 2 times

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