Full Text Journal Articles by
Author Vivek Sharma

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Recent developments in social network disruption approaches to manage bacterial plant diseases

Shabnam Katoch, Nidhi Kumari, Richa Salwan, Vivek Sharma, P N Sharma,

Biotic stresses are one of the major constraints to enhance the agricultural production. Among various biotic stresses, bacterial plant pathogens are often difficult to manage. Further, development of antibiotics resistance in these pathogens led to the emergence of more virulent multidrug resistant strains and hence the management of bacterial pathogens ... Read more >>

Biol Control (Biological control.)
[2020, 150:Not Available]

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Tempering Macrophage Plasticity for Controlling SARS-CoV-2 Infection for Managing COVID-19 Disease.

Devinder Toor, Aklank Jain, Shivani Kalhan, Harmesh Manocha, Vivek Kumar Sharma, Payal Jain, Vishwas Tripathi, Hridayesh Prakash,

Front Pharmacol (Frontiers in pharmacology)
[2020, 11:570698]

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Cerebral venous sinus thrombosis in pediatric nephrotic syndrome.

Sidharth Kumar Sethi, Vivek Sharma, Ronith Chakraborty, Vijay Kher, Rupesh Raina,

Kidney Int (Kidney international)
[2020, 98(4):1056]

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Elevated plasma hemoglobin in COVID-19-related illnesses: a critical appraisal.

Nishant R Tiwari, Nagnath K Redewad, Apurva A Ketkar, Vivek R Sharma,

Ann Hematol (Annals of hematology)
[2020, :]

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Insulin resistance and bioenergetic manifestations: Targets and approaches in Alzheimer's disease.

Vivek Kumar Sharma, Thakur Gurjeet Singh,

<h4>Aim</h4>Insulin has a well-established role in cognition, neuronal detoxification and synaptic plasticity. Insulin transduction affect neurotransmitter functions, influence bioenergetics and regulate neuronal survival through regulating glucose energy metabolism and downward pathways.<h4>Methods</h4>A systematic literature review of PubMed, Medline, Bentham, Scopus and EMBASE (Elsevier) databases was carried out with the help of ... Read more >>

Life Sci (Life sciences)
[2020, 262:118401]

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C3 inhibition with pegcetacoplan in subjects with paroxysmal nocturnal hemoglobinuria treated with eculizumab

Carlos de Castro, Federico Grossi, Ilene Ceil Weitz, Jaroslaw Maciejewski, Vivek Sharma, Eloy Roman, Robert A. Brodsky, Lisa Tan, Carl Di Casoli, Delphine El Mehdi, Pascal Deschatelets, Cedric Francois,

Abstract Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired, life‐threatening hematologic disease characterized by chronic complement‐mediated hemolysis and thrombosis. Despite treatment with eculizumab, a C5 inhibitor, 72% of individuals remain anemic. Pegcetacoplan (APL‐2), a PEGylated C3 inhibitor, has the potential to provide more complete hemolysis control in patients with PNH. This ... Read more >>

Am J Hematol (American journal of hematology)
[2020, 95(11):1334-1343]

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Nuances in the management of acquired hemophilia A in an elderly patient with large granular lymphocytic leukemia.

Nishant R Tiwari, Kaustubh S Chaudhari, Vrushab Rao, Vivek R Sharma,

Blood Res (Blood research)
[2020, 55(3):180-181]

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Spontaneous Regression of Advanced Hepatocellular Carcinoma.

Dhiraj J Sonbare, Rupal Bandi, Vivek Sharma, Thomas Cacciarelli, Obaid S Shaikh,

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality. The tumor carries poor prognosis with curative therapeutic options limited to surgical resection, tumor ablation, and liver transplantation. Rarely, there is spontaneous regression of the tumor. We describe the case of a 74-year-old male with cirrhosis from non-alcoholic steatohepatitis who ... Read more >>

Case Rep Gastroenterol (Case reports in gastroenterology)
[2020, 14(3):491-496]

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Coupling of quinone dynamics to proton pumping in respiratory complex I.

Outi Haapanen, Marco Reidelbach, Vivek Sharma,

Respiratory complex I (NADH:quinone oxidoreductase) plays a central role in generating the proton electrochemical gradient in mitochondrial and bacterial membranes, which is needed to generate ATP. Several high-resolution structures of complex I have been determined, revealing its intricate architecture and complementing the biochemical and biophysical studies. However, the molecular mechanism ... Read more >>

Biochim Biophys Acta Bioenerg (Biochimica et biophysica acta. Bioenergetics)
[2020, 1861(12):148287]

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An Unusual Amino Acid Substitution Within Hummingbird Cytochrome c Oxidase Alters a Key Proton-Conducting Channel.

Cory D Dunn, Bala Anı Akpınar, Vivek Sharma,

Hummingbirds in flight exhibit the highest mass-specific metabolic rate of all vertebrates. The bioenergetic requirements associated with sustained hovering flight raise the possibility of unique amino acid substitutions that would enhance aerobic metabolism. Here, we have identified a non-conservative substitution within the mitochondria-encoded cytochrome <i>c</i> oxidase subunit I (COI) that ... Read more >>

G3 (Bethesda) (G3 (Bethesda, Md.))
[2020, 10(7):2477-2485]

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Antiplatelet Agents in Sepsis-Putting it all together: A Call to Action.

Nishant R Tiwari, Kaustubh S Chaudhari, Richa Sharma, Kevin P Haas, Vivek R Sharma,

<b>How to cite this article:</b> Tiwari NR, Chaudhari KS, Sharma R, Haas KP, Sharma VR. Antiplatelet Agents in Sepsis-Putting it all together: A Call to Action. Indian J Crit Care Med 2020;24(6):483-484. ... Read more >>

Indian J Crit Care Med (Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine)
[2020, 24(6):483-484]

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Implementation of Perioperative Point-of-Care Platelet Function Analyses Reduces Transfusion Requirements in Cardiac Surgery: A Retrospective Cohort Study.

Lihui Wang, Oswaldo Valencia, Simon Phillips, Vivek Sharma,

<h4>Background</h4> Platelet dysfunction is a common cause of bleeding, perioperative blood transfusion, and surgical re-exploration in cardiac surgical patients. We evaluated the effect of incorporating a platelet function analyzer utilizing impedance aggregometry (Multiplate, Roche, Munich, Germany) into our local transfusion algorithm on the rate of platelet transfusion and postoperative blood loss ... Read more >>

Thorac Cardiovasc Surg (The Thoracic and cardiovascular surgeon)
[2020, :]

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Heterologous expression of pepper mild mottle virus coat protein encoding region and its application in immuno-diagnostics.

Nidhi Kumari, Vivek Sharma, Priyankaben Patel, P N Sharma,

Pepper mild mottle virus (PMMoV), a tobamovirus of family <i>Virgaviridae</i> affects the quality and quantity of Capsicum. PMMoV is highly contagious, capable of transmitting through infected seeds and soil. Symptoms are more severe when crop is infected at young stage but remain unnoticed when infection takes place at maturity. Therefore, ... Read more >>

Virusdisease (Virusdisease)
[2020, 31(3):323-332]

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Whey protein-iron or zinc complexation decreases pro-oxidant activity of iron and increases iron and zinc bioavailability

B G Shilpashree, Sumit Arora, Suman Kapila, Vivek Sharma,

Iron and zinc are involved in various functions and their deficiency may lead to several health issues. Fortification of these micronutrients in food is considered as the most effective approach to control deficiencies. Due to high reactivity, iron fortification involves various challenges with respect to oxidative stability and bioaccessibility. Whey ... Read more >>

Lebensm Wiss Technol (Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire)
[2020, 126:Not Available]

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Effect of Yoga Therapy on Disease Activity, Inflammatory Markers, and Heart Rate Variability in Patients with Rheumatoid Arthritis.

Selvakumar Ganesan, Girwar Singh Gaur, Vir Singh Negi, Vivek Kumar Sharma, Gopal Krushna Pal,

<b><i>Background:</i></b> Rheumatoid arthritis (RA) is an immune-mediated inflammatory disease. Antirheumatoid treatment reduces disease activity and inflammation, but not all patients respond to treatment. Autonomic dysfunction is common in RA leading to frequent cardiovascular complications. Yoga therapy may be useful in these patients, but there are little data on the effect ... Read more >>

J Altern Complement Med (Journal of alternative and complementary medicine (New York, N.Y.))
[2020, 26(6):501-507]

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Genome wide underpinning of antagonistic and plant beneficial attributes of Bacillus sp. SBA12.

Richa Salwan, Vivek Sharma,

The plant beneficial microorganisms in rhizosphere are promising candidates to counter plant biotic and abiotic stresses. In the present study, Bacillus sp. SBA12 antagonistic to plant pathogenic fungi such as Phytophthora infestans and Sclerotinia sclerotiorum was explored. The complete genome of SBA12 comprises 5,297,566 bp size with GC content 49% and ... Read more >>

Genomics (Genomics)
[2020, 112(4):2894-2902]

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Presence of polyadenylated 3’ tail in RNA of Pepper mild mottle virus allows the Oligo(dT)18 in Priming cDNA Synthesis of its genomic RNA template

Nidhi Kumari, Vivek Sharma, Sneha Choudhary, P.N. Sharma,

The PCR amplification of majority of the ssRNA of both genomic and non-genomic mRNA is accomplished by RT-PCR. The mRNA is subjected to cDNA synthesis using reverse transcriptase and either Oligo(dT)18, or random or gene specific reverse primers based priming strategies. The choice of primer largely depends on the nature ... Read more >>

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Proton motive function of the terminal antiporter-like subunit in respiratory complex I.

Amina Djurabekova, Outi Haapanen, Vivek Sharma,

In the aerobic respiratory chains of many organisms, complex I functions as the first electron input. By reducing ubiquinone (Q) to ubiquinol, it catalyzes the translocation of protons across the membrane as far as ~200 Å from the site of redox reactions. Despite significant amount of structural and biochemical data, the ... Read more >>

Biochim Biophys Acta Bioenerg (Biochimica et biophysica acta. Bioenergetics)
[2020, 1861(7):148185]

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Awareness, attitude, and practice of dental practitioners toward management of endodontically treated teeth and factors associated with it: A questionnaire descriptive survey.

Deepak Sharma, Sneh Agrawal, Parag Gangurde, Sumeet Agarwal, Reema Srichand, Vivek Sharma,

<h4>Background</h4>Endodontically treated teeth should be prosthodontically managed properly to add life to the teeth, and hence the main aim of this study was to explore awareness, attitude, and practice of dental practitioners toward management of endodontically treated teeth and factors associated with it.<h4>Materials and methods</h4>It was a cross-sectional, descriptive questionnaire ... Read more >>

J Family Med Prim Care (Journal of family medicine and primary care)
[2020, 9(2):1113-1118]

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Spatiotemporal analysis of drug-resistant TB patients registered in selected districts of Karnataka, South India: a cross-sectional study.

Basavaraj Poojar, K Ashok Shenoy, Poonam R Naik, Ashwin Kamath, Jaya Prasad Tripathy, P Prasanna Mithra, Mukta N Chowta, M N Badarudeen, Narasimhaswamy Nagalakshmi, Vivek Sharma, Amrita N Shamanewadi, Pruthu Thekkur,

Background:Tuberculosis (TB) depicts heterogeneous spatial patterns with geographical aggregation of TB cases due to either ongoing person-to-person transmission or reactivation of latent infection in a community sharing risk factor. In this regard, we aimed to assess the spatiotemporal aggregation of drug-resistant TB (DR-TB) patients notified to the national TB program ... Read more >>

Trop Med Health (Tropical medicine and health)
[2020, 48:15]

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Molecular imprints of plant beneficial Streptomyces sp. AC30 and AC40 reveal differential capabilities and strategies to counter environmental stresses.

Richa Salwan, Vivek Sharma, Anu Sharma, Ankita Singh,

Streptomyces and their biomolecules are well explored for antibiotics production, bioremediation and alleviating the plant stresses due to their plant beneficial attributes. Therefore, due to plethora of biological attributes, the accurate portraying of molecular capabilities of these microorganisms at genomic level is of paramount importance. Here, we have evaluated biochemical ... Read more >>

Microbiol Res (Microbiological research)
[2020, 235:126449]

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Page Kidney Complicating Kidney Biopsy after Stopping Apixaban: A Physician's Dilemma.

Macaulay A C Onuigbo, Vivek Sharma, Omotola Balogun, Allina Ghimire,

Page kidney was described by Page, following very elaborate experiments with animal kidneys in 1939, with persistent arterial hypertension from "cellophane perinephritis." Subsequently, it was reported after trauma, from renal cysts and tumors, and from intrarenal hematoma complicating percutaneous kidney biopsy. We describe Page kidney associated with acute kidney injury ... Read more >>

Indian J Nephrol (Indian journal of nephrology)
[2020, 30(3):201-203]

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Post-Renal Biopsy Acute Kidney Injury and Page Kidney from Intra-Renal Hematoma Aggravated by Reversible Contrast-Induced Nephropathy Following Renal Arterial Embolization.

Macaulay A Chukwukadibia Onuigbo, Vivek Sharma, Omotola O Balogun, Allina Ghimire,

BACKGROUND Page kidney was described by Dr. Irving Page in animal kidneys in 1939 with renal failure and persistent arterial hypertension from "cellophane perinephritis". By 2009, about 100 cases of Page kidney had been reported. Bleeding complications after percutaneous kidney biopsy has, however, been well described. Moreover, the perioperative management ... Read more >>

Am J Case Rep (The American journal of case reports)
[2020, 21:e919701]

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Enablers and Challenges in the Implementation of Active Case Findings in a Selected District of Karnataka, South India: A Qualitative Study.

Amrita N Shamanewadi, Poonam R Naik, Pruthu Thekkur, Suwarna Madhukumar, Abhay Subhashrao Nirgude, M B Pavithra, Basavaraj Poojar, Vivek Sharma, Arnav Prashanth Urs, B V Nisarga, N Shakila, Sharath Burugina Nagaraja,

Background:Active case finding (ACF) for tuberculosis (TB) is a promising tool to enhance early case detection among marginalized populations. As opposed to passive case finding, it involves systematically searching for TB in individuals who would not spontaneously present for care. The National TB Program (NTP) of India has initiated ACF ... Read more >>

Tuberc Res Treat (Tuberculosis research and treatment)
[2020, 2020:9746329]

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Bioprospecting Psychrotrophic Bacteria for Serine-Type Proteases from the Cold Areas of Western Himalayas.

Richa Salwan, Vivek Sharma, Ramesh Chand Kasana, Arvind Gulati,

The aim of present study was to analyze the prevalence of protease diversity among psychrotrophic bacteria in Lahaul and Spiti of the Western Himalayas. A total of 459 bacteria were screened and protease activity was observed in 150 isolates at 5 °C. Furthermore, 55 isolates showed protease activity up to pH ... Read more >>

Curr Microbiol (Current microbiology)
[2020, 77(5):795-806]

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