Full Text Journal Articles by
Author Vishnumurthy Shushrutha Hedna


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Benefits of an interdisciplinary stroke clinic: addressing a gap in physical therapy at post-stroke neurology follow-up.

Nandakumar Nagaraja, Alison R Kraus, Dorian K Rose, Esther B Olasoji, Anna Y Khanna, Alexis N Simpkins, Christina A Wilson, Rondalyn R Dickens, Vishnumurthy Shushrutha Hedna, Carolyn Geis, Teddy Youn, Michelle M Musalo,

<h4>Background and purpose</h4>An interdisciplinary stroke clinic (ISC) can improve communication and identify people post-stroke who have not reached their full recovery potential. We describe the characteristics of participants who underwent physical therapy (PT) evaluation in addition to their outpatient neurology evaluation and identify the association of assessment scales that predicted ... Read more >>

Disabil Rehabil (Disability and rehabilitation)
[2021, :1-6]

Cited: 0 times

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Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.

S Claiborne Johnston, J Donald Easton, Mary Farrant, William Barsan, Robin A Conwit, Jordan J Elm, Anthony S Kim, Anne S Lindblad, Yuko Y Palesch, ,

<h4>Background</h4>Combination antiplatelet therapy with clopidogrel and aspirin may reduce the rate of recurrent stroke during the first 3 months after a minor ischemic stroke or transient ischemic attack (TIA). A trial of combination antiplatelet therapy in a Chinese population has shown a reduction in the risk of recurrent stroke. We ... Read more >>

N Engl J Med (The New England journal of medicine)
[2018, 379(3):215-225]

Cited: 171 times

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Results of the ICTuS 2 Trial (Intravascular Cooling in the Treatment of Stroke 2).

Patrick Lyden, Thomas Hemmen, James Grotta, Karen Rapp, Karin Ernstrom, Teresa Rzesiewicz, Stephanie Parker, Mauricio Concha, Syed Hussain, Sachin Agarwal, Brett Meyer, Julie Jurf, Irfan Altafullah, Rema Raman, ,

<h4>Background and purpose</h4>Therapeutic hypothermia is a potent neuroprotectant approved for cerebral protection after neonatal hypoxia-ischemia and cardiac arrest. Therapeutic hypothermia for acute ischemic stroke is safe and feasible in pilot trials. We designed a study protocol to provide safer, faster therapeutic hypothermia in stroke patients.<h4>Methods</h4>Safety procedures and 4°C saline infusions ... Read more >>

Stroke (Stroke)
[2016, 47(12):2888-2895]

Cited: 55 times

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Intensive Blood-Pressure Lowering in Patients with Acute Cerebral Hemorrhage.

Adnan I Qureshi, Yuko Y Palesch, William G Barsan, Daniel F Hanley, Chung Y Hsu, Renee L Martin, Claudia S Moy, Robert Silbergleit, Thorsten Steiner, Jose I Suarez, Kazunori Toyoda, Yongjun Wang, Haruko Yamamoto, Byung-Woo Yoon, ,

<h4>Background</h4>Limited data are available to guide the choice of a target for the systolic blood-pressure level when treating acute hypertensive response in patients with intracerebral hemorrhage.<h4>Methods</h4>We randomly assigned eligible participants with intracerebral hemorrhage (volume, <60 cm(3)) and a Glasgow Coma Scale (GCS) score of 5 or more (on a scale ... Read more >>

N Engl J Med (The New England journal of medicine)
[2016, 375(11):1033-1043]

Cited: 264 times

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Thoracoscopic Ablation With Appendage Ligation Versus Medical Therapy for Stroke Prevention: A Proof-of-Concept Randomized Trial.

Thomas M Beaver, Vishnumurthy Shushrutha Hedna, Anna Y Khanna, William M Miles, Catherine C Price, Ilona M Schmalfuss, Seyed Hossein Aalaei-Andabili, Michael F Waters,

<h4>Objective</h4>Atrial fibrillation (AF) has a demonstrable effect on quality of life (QOL). Recurrent stroke occurs in 10% of patients with AF. The objective of this study was to demonstrate proof of concept that thoracoscopic pulmonary vein isolation and atrial appendage ligation (TPVIAL) could prevent recurrent stroke and could potentially improve ... Read more >>

Innovations (Phila) (Innovations (Philadelphia, Pa.))
[2016, 11(2):99-105]

Cited: 4 times

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Recurrence of Lobar Hemorrhage: A Red Flag for Cerebral Amyloid Angiopathy-related Inflammation?

Vaibhav Rastogi, Lauren L Donnangelo, Ganesh Asaithambi, Sharatchandra Bidari, Anna Y Khanna, Vishnumurthy Shushrutha Hedna,

Background. Recurrent lobar intracerebral hemorrhage is more commonly associated with cerebral amyloid angiopathy and less likely associated with hypertension. Cerebral amyloid angiopathy-related inflammation is a subgroup of cerebral amyloid angiopathy that can present with lobar intracerebral hemorrhage, encephalopathy, and seizures; wherein corticosteroids may facilitate favorable outcome. Whether recurrence of lobar ... Read more >>

Innov Clin Neurosci (Innovations in clinical neuroscience)
[2015, 12(5-6):20-26]

Cited: 3 times

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Symptomatic improvement of traumatic dysgeusia from an occipital nerve block.

Vaibhav Rastogi, Atish Patel, Abhishek D Lunagariya, Vishnumurthy Shushrutha Hedna,

Neurol India (Neurology India)
[2015, 63(2):259-260]

Cited: 0 times

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Validity of Laser Doppler Flowmetry in Predicting Outcome in Murine Intraluminal Middle Cerebral Artery Occlusion Stroke.

Vishnumurthy Shushrutha Hedna, Saeed Ansari, Shima Shahjouei, Peter Y Cai, Abdullah Shafique Ahmad, J Mocco, Adnan I Qureshi,

<h4>Background</h4>Laser Doppler flowmetry (LDF) can reliably reflect brain perfusion in experimental stroke by monitoring both the degree and the duration of relative regional cerebral blood flow (rCBF). Variation in rCBF was continuously monitored in 68 mice undergoing middle cerebral artery occlusion (MCAO) and 25 mice undergoing sham-operation and documented as ... Read more >>

J Vasc Interv Neurol (Journal of vascular and interventional neurology)
[2015, 8(3):74-82]

Cited: 11 times

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Taming glutamate excitotoxicity: strategic pathway modulation for neuroprotection.

Ming Jia, Steve A Noutong Njapo, Vaibhav Rastogi, Vishnumurthy Shushrutha Hedna,

Much work has been carried out in recent years showing that elevated glutamate levels in the extracellular environment of the central nervous system play a pivotal role in neurodegeneration in acute CNS injuries. With the elucidation of the mechanism governing glutamate excitotoxicity, researchers are devising therapeutic strategies to target different ... Read more >>

CNS Drugs (CNS drugs)
[2015, 29(2):153-162]

Cited: 17 times

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Treatment of stroke related refractory brain edema using mixed vasopressin antagonism: a case report and review of the literature.

Vishnumurthy Shushrutha Hedna, Sharathchandra Bidari, David Gubernick, Saeed Ansari, Irawan Satriotomo, Asif A Khan, Adnan I Qureshi,

<h4>Background</h4>Elevated intracranial pressure from cerebral edema is the major cause of early mortality in acute stroke. Current treatment strategies to limit cerebral edema are not particularly effective. Some novel anti-edema measures have shown promising early findings in experimental stroke models. Vasopressin antagonism in stroke is one such target which has ... Read more >>

BMC Neurol (BMC neurology)
[2014, 14:213]

Cited: 6 times

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Vagus nerve stimulation in ischemic stroke: old wine in a new bottle.

Peter Y Cai, Aakash Bodhit, Roselle Derequito, Saeed Ansari, Fawzi Abukhalil, Spandana Thenkabail, Sarah Ganji, Pradeepan Saravanapavan, Chandana C Shekar, Sharatchandra Bidari, Michael F Waters, Vishnumurthy Shushrutha Hedna,

Vagus nerve stimulation (VNS) is currently Food and Drug Administration-approved for treatment of both medically refractory partial-onset seizures and severe, recurrent refractory depression, which has failed to respond to medical interventions. Because of its ability to regulate mechanisms well-studied in neuroscience, such as norepinephrine and serotonin release, the vagus nerve ... Read more >>

Front Neurol (Frontiers in neurology)
[2014, 5:107]

Cited: 30 times

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Role of vasopressin and its antagonism in stroke related edema.

Pouya A Ameli, Neema J Ameli, David M Gubernick, Saeed Ansari, Shekher Mohan, Irawan Satriotomo, Alexis K Buckley, Christopher W Maxwell, Vignesh H Nayak, Vishnumurthy Shushrutha Hedna,

Although many approaches have been tried in the attempt to reduce the devastating impact of stroke, tissue plasminogen activator for thromboembolic stroke is the only proved, effective acute stroke treatment to date. Vasopressin, an acute-phase reactant, is released after brain injury and is partially responsible for the subsequent inflammatory response ... Read more >>

J Neurosci Res (Journal of neuroscience research)
[2014, 92(9):1091-1099]

Cited: 9 times

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Atrial Fibrillation - A Common Ground for Neurology and Cardiology.

Fawzi Abukhalil, Aakash Bodhit, Peter Y Cai, Saeed Ansari, Spandana Thenkabail, Sarah Ganji, Pradeepan Saravanapavan, Chandana Chandra Shekhar, Michael F Waters, Thomas M Beaver, Vishnumurthy Shushrutha Hedna,

Atrial fibrillation (AF) has a huge impact on clinical stroke because it is the primary cause of cardio-embolism, which constitutes ~20% of all strokes. As a result, there is a great need to explore safer and more effective primary and secondary prophylactic agents. In this article, we discuss the overlapping ... Read more >>

J Atr Fibrillation (Journal of atrial fibrillation)
[2013, 6(2):550]

Cited: 0 times

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A Non-Surgeon's Guide to Surgical Management of Atrial Fibrillation.

Peter Y Cai, Roselle Derequito, Monica Mishra, Spandana Tenkabail, Aakash Bodhit, Saeed Ansari, Sarah Ganji, Pradeepan Saravanapavan, Chandana Chandra Shekhar, Fawzi Abukhalil, Michael F Waters, Thomas M Beaver, Vishnumurthy Shushrutha Hedna,

Atrial fibrillation (AF) is the most common cardiac arrhythmia associated with substantial increases in death, heart failure, and stroke. It is important for healthcare providers in all fields to also gain an understanding of the novel techniques used in surgical treatment of AF. Clinicians must now decide between many different ... Read more >>

J Surg (Northborough) (Journal of surgery (Northborough, Mass.))
[2013, 1(2):]

Cited: 0 times

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Role of inflammatory markers in Takayasu arteritis disease monitoring.

Timothy E O'Connor, Haley E Carpenter, Sharatchandra Bidari, Michael F Waters, Vishnumurthy Shushrutha Hedna,

<h4>Background</h4>Takayasu arteritis (TA) is an idiopathic large-vessel vasculitis that can result in significant morbidity and mortality secondary to progressive stenosis and occlusion. Monitoring disease progression is crucial to preventing relapse, but is often complicated by the lack of clinical symptoms in the setting of active disease. Although acute phase reactants ... Read more >>

BMC Neurol (BMC neurology)
[2014, 14:62]

Cited: 10 times

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Visual-olfactory hallucinatory synesthesia: the Charles Bonnet Syndrome with olfactory hallucinations.

David Gubernick, Pouya Ameli, Qingshan Teng, Arnaldo Velez, Kenneth M Heilman, Vishnumurthy Shushrutha Hedna,

Cortex (Cortex; a journal devoted to the study of the nervous system and behavior)
[2014, 50:204-207]

Cited: 2 times

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Intracranial hypotension masquerading as nonconvulsive status epilepticus: report of 3 cases.

Vishnumurthy Shushrutha Hedna, Abhay Kumar, Bayard Miller, Sharathchandra Bidari, Arash Salardini, Michael F Waters, Maria Hella, Edward Valenstein, Stephan Eisenschenk,

Intracranial hypotension (IH) has been a known entity in neurocritical care since 1938. Even though many cases are spontaneous, the incidence of intracranial hypotension in the neurocritical care setting is increasing by virtue of the increased number of neurosurgical interventions. Whether spontaneous or secondary in etiology, diagnosis of IH usually ... Read more >>

J Neurosurg (Journal of neurosurgery)
[2014, 120(3):624-627]

Cited: 3 times

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Praxis and writing in a right-hander with crossed aphasia.

Adam D Falchook, D Brandon Burtis, Lealani M Acosta, Liliana Salazar, Vishnumurthy Shushrutha Hedna, Anna Y Khanna, Kenneth M Heilman,

Studies of patients with brain lesions have demonstrated that language and praxis are mediated by dissociable networks. However, language has the capacity to influence the selection of purposeful actions. The abilities to use language and to program purposeful movements are often mediated by networks that have anatomic proximity. With hemispheric ... Read more >>

Neurocase (Neurocase)
[2014, 20(3):317-327]

Cited: 0 times

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Hemispheric differences in ischemic stroke: is left-hemisphere stroke more common?

Vishnumurthy Shushrutha Hedna, Aakash N Bodhit, Saeed Ansari, Adam D Falchook, Latha Stead, Kenneth M Heilman, Michael F Waters,

<h4>Background and purpose</h4>Understanding the mechanisms underlying stroke can aid the development of therapies and improve the final outcome. The purposes of this study were to establish whether there are characteristic mechanistic differences in the frequency, severity, functional outcome, and mortality between left- and right-hemisphere ischemic stroke and, given the velocity ... Read more >>

J Clin Neurol (Journal of clinical neurology (Seoul, Korea))
[2013, 9(2):97-102]

Cited: 34 times

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Takayasu's arteritis: Is it a reversible disease? Case Report and Literature Review.

Vishnumurthy Shushrutha Hedna, Akhil Patel, Sharathchandra Bidari, Melissa Elder, Brian L Hoh, Anthony Yachnis, Michael F Waters,

<h4>Background</h4>Takayasu's arteritis (TA) is a rare and potentially devastating condition leading to prolonged morbidity and even death.<h4>Case description</h4>We report an 18-year-old female presenting with an acute ischemic stroke treated with intravenous thrombolysis and subsequent endovascular therapy (ET) with excellent results followed by chronic treatment with immunosuppressants after a formal diagnosis ... Read more >>

Surg Neurol Int (Surgical neurology international)
[2012, 3:132]

Cited: 3 times

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Trends in the management of atrial fibrillation: A neurologist's perspective.

Vishnumurthy Shushrutha Hedna, Christopher G Favilla, Waldo R Guerrero, Akhil Patel, Amareshwari Gottipati, Sharathchandra Bidari, Thomas Beaver, Michael F Waters,

Cardiac embolism, primarily from atrial fibrillation (AF), is implicated in a quarter of all ischemic strokes. In the setting of AF, contraindications to traditional therapies can create a clinical dilemma when choosing an agent for secondary stroke prophylaxis. Newer horizons in the medical and surgical management of AF have helped ... Read more >>

J Cardiovasc Dis Res (Journal of cardiovascular disease research)
[2012, 3(4):255-264]

Cited: 2 times

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Seizure Mimicking Stroke: Role of CT Perfusion.

Vishnumurthy Shushrutha Hedna, Prerak P Shukla, Michael F Waters,

Stroke mimics constitute 15--20% of all cases presenting to the emergency department, prominent among them being seizures, hypoglycemia, tumors, migraines, and posterior reversible leucoencephalopathy. They have also abnormal computerized tomography perfusion (CTP) findings. We report a case where CTP helped us to diagnose and treat a seizure when initial presentation ... Read more >>

J Clin Imaging Sci (Journal of clinical imaging science)
[2012, 2:32]

Cited: 4 times

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Posterior reversible encephalopathy syndrome (PRES) and CT perfusion changes.

Vishnumurthy Shushrutha Hedna, Latha Ganti Stead, Sharathchandra Bidari, Akhil Patel, Amareshwari Gottipati, Christopher G Favilla, Arash Salardini, Aunali Khaku, Diana Mora, Ajay Pandey, Het Patel, Michael F Waters,

Posterior reversible encephalopathy syndrome (PRES) can present with focal neurologic deficits, mimicking a stroke and can often represent a diagnostic challenge when presenting atypically. A high degree of suspicion is required in the clinical setting in order to yield the diagnosis. Cerebral CT perfusion (CTP) is utilized in many institutions ... Read more >>

Int J Emerg Med (International journal of emergency medicine)
[2012, 5:12]

Cited: 16 times

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