Full Text Journal Articles by
Author Viqar Uddin Ahmad

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Chemical composition, antioxidant and antimicrobial potential of essential oils from different parts of Daphne mucronata Royle.

Iqra Ashraf, Muhammad Zubair, Komal Rizwan, Nasir Rasool, Muhammad Jamil, Shakeel Ahmad Khan, Rasool Bakhsh Tareen, Viqar Uddin Ahmad, Abid Mahmood, Muhammad Riaz, M Zia-Ul-Haq, Hawa Ze Jaafar,

This research work was executed to determine chemical composition, anti-oxidant and anti-microbial potential of the essential oils extracted from the leaves and stem of Daphne mucronata Royle. From leaves and stem oils fifty-one different constituents were identified through GC/MS examination. The antioxidant potential evaluated through DPPH free radical scavenging activity ... Read more >>

Chem Cent J (Chemistry Central journal)
[2018, 12(1):135]

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Palladium(0) catalyzed Suzuki cross-coupling reaction of 2,5-dibromo-3-methylthiophene: selectivity, characterization, DFT studies and their biological evaluations.

Komal Rizwan, Muhammad Zubair, Nasir Rasool, Tariq Mahmood, Khurshid Ayub, Noorjahan Banu Alitheen, Muhammad Nazirul Mubin Aziz, Muhammad Nadeem Akhtar, Faiz-Ul-Hassan Nasim, Snober Mona Bukhary, Viqar Uddin Ahmad, Mubeen Rani,

Thiophene derivatives have shown versatile pharmacological activities. The Suzuki reaction proved a convenient method for C-C bond formations in organic molecules. In the present research work novel derivatives of 2,5-dibromo-3-methylthiophene (3a-k and 3l-p) has been synthesized, via Suzuki coupling reaction in low to moderate yields. A wide range of functional ... Read more >>

(Chemistry Central journal)
[2018, 12(1):49]

Cited: 2 times

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Laceioside, a new cycloartane saponin from Astragalus tephrosioides Boiss. var. lacei (Ali) Kirchoff.

Viqar Uddin Ahmad, Faryal Vali Mohammad, Rasool Bakhsh Tareen,

Phytochemical investigation of the aerial parts of Astragalus tephrosioides Boiss. var. lacei (Ali) Kirchoff. (Family Fabaceae) resulted in the isolation of a new cycloartane glycoside laceioside (1). The structure of the previously undescribed compound 1 was established as 16β-acetyloxy-3- O-β-d-glucopyranosyloxy-cycloartan-11α,24ξ, 25-triol. The structure elucidation of compound 1 was based primarily ... Read more >>

Nat Prod Res (Natural product research)
[2019, 33(3):393-399]

Cited: 1 time

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Isolation, purification, structural elucidation and antimicrobial activities of kocumarin, a novel antibiotic isolated from actinobacterium Kocuria marina CMG S2 associated with the brown seaweed Pelvetia canaliculata.

Bushra Uzair, Farid Menaa, Barkat Ali Khan, Faryal Vali Mohammad, Viqar Uddin Ahmad, Ryad Djeribi, Bouzid Menaa,

Screening of seaweed-associated bacteria capable of producing antimicrobials.Fifteen microbial strains, associated to the brown seaweed Pelvetia canaliculata (Linnaeus) attached to the rocks of Sonmiani Beach (Karachi, Pakistan), were screened. Crude extract filtrates of CMG S2 strain grew on Zobell marine agar (ZMA) had the most remarkable antimicrobial activity. Based on ... Read more >>

Microbiol. Res. (Microbiological research)
[2018, 206:186-197]

Cited: 6 times

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Antitumor evaluation of two selected Pakistani plant extracts on human bone and breast cancer cell lines.

Nadja Engel, Iftikhar Ali, Anna Adamus, Marcus Frank, Akber Dad, Sajjad Ali, Barbara Nebe, Muhammad Atif, Muhammad Ismail, Peter Langer, Viqar Uddin Ahmad,

The medicinal plants Vincetoxicum arnottianum (VSM), Berberis orthobotrys (BORM), Onosma hispida (OHRM and OHAM) and Caccinia macranthera (CMM) are used traditionally in Pakistan and around the world for the treatment of various diseases including cancer, dermal infections, uterine tumor, wounds etc. The present study focuses on the investigation of the ... Read more >>

BMC Complement Altern Med (BMC complementary and alternative medicine)
[2016, 16:244]

Cited: 4 times

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Biotransformation of monoterpenoids and their antimicrobial activities.

Haq Nawaz Bhatti, Saleha Suleman Khan, Ajmal Khan, Mubeen Rani, Viqar Uddin Ahmad, Muhammad Iqbal Choudhary,

Biotransformation is an economically and ecologically viable technology which has been used extensively to modify the structures of many classes of biologically active products. The discovery of novel antimicrobial metabolites from biotransformation is an important alternative to overcome the increasing levels of drug resistance by plant and human pathogens. Monoterpenes, ... Read more >>

Phytomedicine (Phytomedicine : international journal of phytotherapy and phytopharmacology)
[2014, 21(12):1597-1626]

Cited: 14 times

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A new secoiridoid glycosidic lignan ester from the leaves of Olea ferruginea.

Muhammad Ali Hashmi, Afsar Khan, Umar Farooq, Mubeen Rani, Viqar Uddin Ahmad, Abdur Rahman Khan,

Magn Reson Chem (Magnetic resonance in chemistry : MRC)
[2015, 53(2):163-166]

Cited: 0 times

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Chemical analysis and calcium channel blocking activity of the essential oil of Perovskia abrotanoides.

Abdul Jabbar Shah, Munawwer Rasheed, Qaiser Jabeen, Amir Ahmed, Rasool Bakhsh Tareen, Anwarul Hassan Gilani, Muhammad Nadir, Viqar Uddin Ahmad,

The aim of this study was to investigate the chemical composition and provide a pharmacological base for the medicinal use of the essential oil of Perovskia abrotanoides (Pa.Oil) in gastrointestinal disorders, such as colic. The chemical investigation resulted in the identification of 26 compounds, of which tricyclene, beta-trans-ocimene, terpinene-4-acetate, terpinen-4-ol, ... Read more >>

Nat Prod Commun (Natural product communications)
[2013, 8(11):1633-1636]

Cited: 5 times

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A new glucuronolactone glycoside phoenixoside B from the seeds of Phoenix dactylifera.

Sumbul Azmat, Rehana Ifzal, Faryal Vali Mohammad, Viqar Uddin Ahmad, Aqib Zahoor,

A new glucuronolactone glycoside, phoenixoside B (1), has been isolated from the n-butanol soluble fraction of seeds of Phoenix dactylifera. The structure was characterized as 1-(1'-ethyl-beta-D-glucosyl)-4,5-diethyl-[alpha-D-glucofuranourono-6,3-lactone] on the basis of 1D and 2D-NMR spectroscopy and high-resolution mass spectrometry. ... Read more >>

Nat Prod Commun (Natural product communications)
[2013, 8(9):1289-1290]

Cited: 0 times

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Urease inhibitory activity of ursane type sulfated saponins from the aerial parts of Zygophyllum fabago Linn.

Saleha Suleman Khan, Ajmal Khan, Afsar Khan, Abdul Wadood, Umar Farooq, Amir Ahmed, Aqib Zahoor, Viqar Uddin Ahmad, Bilge Sener, Nurgun Erdemoglu,

Five ursane type sulfated saponins have been isolated from the aerial parts of Zygophyllum fabago Linn. (locally called Chashum). The urease inhibitory effects of these compounds have been investigated for the first time as well as their molecular docking studies have also been carried out to check the structure-activity relationship. ... Read more >>

Phytomedicine (Phytomedicine : international journal of phytotherapy and phytopharmacology)
[2014, 21(3):379-382]

Cited: 4 times

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A new monodesmosidic triterpenoid saponin from the leaves of Pometia pinnata.

Faryal Vali Mohammad, Mushtaq Noorwala, Viqar Uddin Ahmad, Aqib Zahoor, Nordin H J Lajis,

Phytochemical investigation of the leaves of Pometia pinnata resulted in the isolation of a new triterpenoid saponin (1), together with a known compound, kaemferol 3-O-alpha-L-rhamnopyranoside (2). The structure of 1 was established as 3-O-[alpha-L-arabinofuranosyl-(1-->4)-alpha-L-rhamnopyranosyl-(1-->2)-alpha-L-arabinopyranosyl]-hederagenin. The structure elucidation of the isolated compounds was based primarily on 1D- and 2D-NMR techniques, including ... Read more >>

Nat Prod Commun (Natural product communications)
[2012, 7(11):1423-1426]

Cited: 1 time

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Chemical and antimicrobial studies on the essential oil from Salvia santolinifolia Boiss.

Muhammad Nadir, Munawwer Rasheed, Sikandar Khan Sherwani, Shahana Urooj Kazmi, Viqar Uddin Ahmad,

In view of the reputation of genus Salvia in folklore medicine and its abundance in our region, the chemical composition and antimicrobial activity of essential oil from S. santolinifolia Boiss. was analyzed. Chemical analysis, using gas chromatography and gas chromatography mass spectrometry, retention indices and C-13 nuclear magnetic resonance spectroscopy ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2013, 26(1):39-52]

Cited: 1 time

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Meliloester, a new melilotic ester from Melilotus alba.

Rasheeda Khatoon, Nikhat Saba, Aqib Zahoor, Shazia Summer, Viqar Uddin Ahmad,

A new melilotic ester, meliloester [2-ethyl-hexyl-3-(2-hydroxyphenyl) propionate], was isolated from the whole plant of Melilotus alba. Its structure was elucidated on the basis of spectroscopic and mass spectrometric analyses, including EI-MS, HR-MS, and UV, IR, 1D and 2D-NMR spectroscopic studies. ... Read more >>

Nat Prod Commun (Natural product communications)
[2012, 7(1):61-62]

Cited: 0 times

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2,4,6-Trichlorophenylhydrazine Schiff bases as DPPH radical and super oxide anion scavengers.

Khalid Mohammed Khan, Zarbad Shah, Viqar Uddin Ahmad, Momin Khan, Muhammad Taha, Fazal Rahim, Sajjad Ali, Nida Ambreen, Shahnaz Perveen, M Iqbal Choudhary, Wolfgang Voelter,

Syntheses of thirty 2,4,6-trichlorophenylhydrazine Schiff bases 1-30 were carried out and evaluated for their in vitro DPPH radical and super oxide anion scavenging activities. Compounds 1-30 have shown a varying degree of DPPH radical scavenging activity and their IC50 values range between 4.05-369.30 µM. The compounds 17, 28, 18, 14, ... Read more >>

Med Chem (Medicinal chemistry (Shariqah (United Arab Emirates)))
[2012, 8(3):452-461]

Cited: 14 times

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Investigation of antitussive and toxicological activity of Ballota limbata in mice.

Rizwan ul Haq, Umar Farooq, Abdul Wahab, Mohsin Raza, Viqar Uddin Ahmad, Rafeeq Alam Khan,

CONTEXT: Ballota limbata Benth. (Lamiaceae) (syn, Otostegia limbata Hook.f.) is a species grown in the North West Frontier Province and the lower hills of West Punjab, Pakistan. Ballota species are renowned for their antispasmodic, antiulcer, diuretic, vermifuge, and especially sedative effects. However, little is known about the biological activity of ... Read more >>

Pharm Biol (Pharmaceutical biology)
[2011, 49(6):627-632]

Cited: 1 time

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Antioxidant, antimicrobial and phytochemical analysis of cichoriumintybus seeds extract and various organic fractions.

Nasir Mehmood, Muhammad Zubaır, Komal Rızwan, Nasır Rasool, Muhammad Shahid, Viqar Uddin Ahmad,

This study was carried out to evaluate the antimicrobial and antioxidant effectiveness of methanolic extract and different fractions (n-butanol, ethyl acetate, chloroform and n-hexane) of C.intybus seeds. The antimicrobial activity was determined by the disc diffusion method and minimum inhibitory concentration (MIC) against a panel of microorganisms (four bacterial strains, ... Read more >>

(Iranian journal of pharmaceutical research : IJPR)
[2012, 11(4):1145-1151]

Cited: 10 times

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Two new ballonigrin-type diterpenoids from the roots of Ballota limbata.

Umar Farooq, Afsar Khan, Ather Farooq Khan, Saleha Suleman Khan, Rizwana Sarwar, Viqar Uddin Ahmad, Amir Waseem,

Two new ballonigrin type lactone diterpenoids, named ballonigrin lactone A and B, have been isolated from the roots of Ballota limbata. Structure elucidation of the isolated compounds was based on spectroscopic {IR, 1H- and 3C-NMR, and 2D-NMR (HMQC, HMBC, COSY and NOESY} and EI-MS data. ... Read more >>

Nat Prod Commun (Natural product communications)
[2012, 7(2):149-150]

Cited: 1 time

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Two new triterpenoids from Zygophyllum eurypterum.

Shazia Iqbal, Afsar Khan, Viqar Uddin Ahmad, Murad Ali Khan, Sadia Bader, Umar Farooq, Saleha Suleman Khan, Aqib Zahoor, Rasool Bakhsh Tareen,

Two new triterpenoids trivially named as atriplicoide A and B were isolated from the n-BuOH extract of the whole plant of Zygophyllum eurypterum. Based on EI-MS, IR, 1H- and 13C-NMR, and 2D-NMR (HMQC, HMBC, COSY and NOESY) data, the structures of the new compounds were determined as 30-carboxy-3beta,24-dihydroxy-urs-28,13beta-lactam-N-acetate (1) and ... Read more >>

Nat Prod Commun (Natural product communications)
[2011, 6(2):179-182]

Cited: 1 time

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Structure elucidation of two new unusual monoterpene glycosides from Euphorbia decipiens, by 1D and 2D NMR experiments.

Ozlem Demirkiran, Gulacti Topcu, Javid Hussain, Viqar Uddin Ahmad, M Iqbal Choudhary,

Two new unusual monoterpene glycosides, (Z)-3,6-dimethyl-3-(β-D-O-glucosylmethylene)cyclohept-4-ene-1-one (1) and 3,6-dimethyl-3-(β-D-O-glucosylmethylene)cycloheptanone (2) have been isolated along with five known compounds, 3-hydroxy-4-methoxybenzoic acid, 6,7-dihydroxycoumarin, luteolin, apigenin 5-O-αl-L-rhamnoside, and pinocembrin-7-O-rutinoside from ethyl acetate extract of Euphorbia decipiens. The structures of the isolated compounds were elucidated by extensive 1D- and 2D-NMR, and mass spectroscopic analyses. ... Read more >>

Magn Reson Chem (Magnetic resonance in chemistry : MRC)
[2011, 49(10):673-677]

Cited: 0 times

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A new megastigmane glycoside, phoenixoside A, from Phoenix dactylifera.

Sumbul Azmat, Aqib Zahoor, Rehana Ifzal, Viqar Uddin Ahmad, Faryal Vali Mohammed,

A new megastigmane glycoside, phoenixoside A (1), has been isolated from the n-butanol--soluble fraction of seeds of Phoenix dactylifera. The structure was characterized as (6S,7Z,9R)-hydroxy-3-oxo-ionol-9-O-beta-D-glucopyranosyl-(1" --> 6')-beta-D-glucopyranoside on the basis of 1D and 2D NMR spectroscopy, high-resolution mass spectrometry, and CD spectroscopy. ... Read more >>

Nat Prod Commun (Natural product communications)
[2012, 7(1):3-4]

Cited: 2 times

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Synthesis of 2,4,6-trichlorophenyl hydrazones and their inhibitory potential against glycation of protein.

Khalid Mohammed Khan, Zarbad Shah, Viqar Uddin Ahmad, Momin Khan, Muhammad Taha, Fazal Rahim, Humera Jahan, Shahnaz Perveen, M Iqbal Choudhary,

2,4,6-Trichlorophenyl hydrazones 1-35 were synthesized and their in vitro antiglycation potential was evaluated. Compounds 14 (IC50 = 27.2 ± 0.00 μM), and 18 (IC50 = 55.7 ± 0.00 μM) showed an excellent activity against glycation of protein, better than the standard (rutin, IC50 = 70 ± 0.50 μM). This study ... Read more >>

Med Chem (Medicinal chemistry (Shariqah (United Arab Emirates)))
[2011, 7(6):572-580]

Cited: 12 times

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A new eudesmane sesquiterpene from Pluchea arguta.

Nikhat Saba, Rasheeda Khatoon, Viqar Uddin Ahmad, Saleha Suleman Khan,

A new eudesmane sesquiterpene, pluchargen A (3-beta-[3'-chloro-2'-hydroxy-2'-methyl butyroyl]-cuauhtemone), was isolated from the whole plant of Pluchea arguta, and the structure was elucidated on the basis of 1- and 2-D NMR spectroscopic studies. ... Read more >>

Nat Prod Commun (Natural product communications)
[2011, 6(1):1-2]

Cited: 9 times

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Studies on the chemical composition and possible mechanisms underlying the antispasmodic and bronchodilatory activities of the essential oil of Artemisia maritima L.

Abdul Jabbar Shah, Anwarul-Hassan Gilani, Kanza Abbas, Munawwer Rasheed, Amir Ahmed, Viqar Uddin Ahmad,

This study describes the chemical composition of the essential oil of Artemisia maritima (Am.Oil) and the pharmacological basis for its medicinal use in gut and airways disorders. Twenty five compounds, composing 93.7% of the oil, were identified; among these, chrysanthenyl propionate and elixene were identified for the first time from ... Read more >>

Arch. Pharm. Res. (Archives of pharmacal research)
[2011, 34(8):1227-1238]

Cited: 10 times

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Two new antioxidant bergenin derivatives from the stem of Rivea hypocrateriformis.

Zamarrud, Iftikhar Ali, Hidayat Hussain, Hidayat Hussain, Viqar Uddin Ahmad, Muhammad Qaiser, Afroze Amyn, Faryal Vali Mohammad,

Two new bergenin derivatives, named rivebergenin A and B (1, and 2), together with two known compounds, bergenin (3) and norbergenin (4) were isolated from the stem of Rivea hypocrateriformis (Desr.) Choisy. The structures of the new compound have been assigned from (1)H and (13)C NMR spectra, DEPT, and by ... Read more >>

Fitoterapia (Fitoterapia)
[2011, 82(4):722-725]

Cited: 4 times

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A new triterpenoid saponin from the stem bark of Pometia pinnata.

Faryal Vali Mohammad, Viqar Uddin Ahmad, Mushtaq Noorwala, Nordin H J Lajis,

Phytochemical investigation of the stem bark of Pometia pinnata resulted in the isolation of a new triterpenoidal saponin. The structure of the new compound, pometin (1), was established as 3-O-[beta-D-glucopyranosyl-(1 --> 2)-beta-D-glucopyranosyl-(1 --> 3)-beta-D-glucopyranosyl]-oleanolic acid based on 1D and 2D-NMR analysis including COSY, 2D J-resolved, HMQC, HMBC correlations and chemical ... Read more >>

Nat Prod Commun (Natural product communications)
[2010, 5(2):191-195]

Cited: 2 times

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